Tannerella forsythia

Dra. Bioq. Laura Gliosca

Laboratorio de Diagnóstico Microbiológico y Molecular

Directora: Dra. Laura Gliosca
Cátedra de Microbiología y Parasitología. Facultad de Odontología –UBA
Prof. Titular: Dra. Susana Molgatini
Tannerella forsythia y factores de patogenicidad
Transmission electron microscope images (A–D) and atomic force microscopy
image (E) of Tannerella forsythia ATCC 43037 wild-type cells and outer
membrane vesicles (OMVs). (A) Ultrathin-sectioned preparation of a cell showing
the biogenesis of an OMV (white triangle) from the outer membrane and coverage
of the nascent OMV with the S-layer.

Friedrich, V., Gruber, C., Nimeth, I., Pabinger, S., Sekot, G., Posch, G., Altmann, F., Messner, P., Andrukhov, O.,
& Schäffer, C. (2015). Outer membrane vesicles of Tannerella forsythia: biogenesis, composition, and
virulence. Molecular oral microbiology, 30(6), 451–473. https://doi.org/10.1111/omi.12104
Tannerella forsythia y factores de patogenicidad

PROTEASA CAPA S
LPS LPS Tripsino (superficial) Glicosidasa
Like

N acetil beta
T forsythia SIALIDASA glucosaminidasa Lipoproteinas

Microvesículas ALFA D
GLUCOSIDASA
 Tannerella forsythia y factores de patogenicidad

Ksiazek, M., Mizgalska, D., Eick, S., Thøgersen, I. B., Enghild, J. J., & Potempa, J. (2015). KLIKK proteases of Tannerella forsythia:
putative virulence factors with a unique domain structure. Frontiers in microbiology, 6, 312. https://doi.org/10.3389/fmicb.2015.00312
 Tannerella forsythia y resorción ósea
GroEL is a molecular
chaperone homologous to
human heat-shock protein 60

Jung, Y. J., Choi, Y. J., An, S. J., Lee, H. R., Jun, H. K., & Choi, B. K. (2017). Tannerella forsythia GroEL induces inflammatory bone
resorption and synergizes with interleukin-17. Molecular oral microbiology, 32(4), 301–313. https://doi.org/10.1111/omi.12172
 bibliografía

Jung, Y. J., Choi, Y. J., An, S. J., Lee, H. R., Jun, H. K., & Choi, B. K. (2017). Tannerella forsythia GroEL induces
inflammatory bone resorption and synergizes with interleukin-17. Molecular oral microbiology, 32(4), 301–313.
https://doi.org/10.1111/omi.12172

Ksiazek, M., Mizgalska, D., Eick, S., Thøgersen, I. B., Enghild, J. J., & Potempa, J. (2015). KLIKK proteases of Tannerella
forsythia: putative virulence factors with a unique domain structure. Frontiers in microbiology, 6, 312.
https://doi.org/10.3389/fmicb.2015.00312

Friedrich, V., Gruber, C., Nimeth, I., Pabinger, S., Sekot, G., Posch, G., Altmann, F., Messner, P., Andrukhov, O., & Schäffer,
C. (2015). Outer membrane vesicles of Tannerella forsythia: biogenesis, composition, and virulence. Molecular oral
microbiology, 30(6), 451–473. https://doi.org/10.1111/omi.12104

Denis Bourgeois et al. Periodontal Pathogens as Risk Factors of Cardiovascular Diseases, Diabetes, Rheumatoid Arthritis,
Cancer, and Chronic Obstructive Pulmonary Disease—Is There Cause for Consideration? Microorganisms 2019, 7, 424;
doi:10.3390/microorganisms7100424