Ners Halimuddin, SKp.,M.Kep.,Sp.

KMB
Medical Surgical Nursing Spesialis
 Therapi Titrasi
 Penggunaan Syring Pump dan Infus Pump
 Tujuan
 Memberikan obat atau cairan secara
bertahap, step by step, menyesuaikan dengan
respon yang dikehendaki.
 Dapat berubah dalam
hitungan jam, menit, detik.
mcg/kgBB/menit mcg/kgBB/jam mcg/menit

mg/jam mg/menit
Golongan Inotropik Positif
Sediaan Ampul 200 mg (5 cc)
Dosis 1 – 20 mcg/kgBB/menit (intravena)
Renal dos : < 5 mcg (Vasodilator)
Inotropic : 5 – 10 mcg
Pressor : > 10 mcg (vasokonstrictor)
Pengenceran 200 mg/50 cc (1 cc = 4 mg = 4000
mikrogram)
Rumus Dosis x BB x menit
Pengenceran
Respon CO, MAP, SVR meningkat
 Dosis 5 microgram/kgBB/menit
 Berat Badan 47 kg.
 Berapa cc pengaturan syring Pump/jam

5 micro x 47 kg x 60 menit
= 4000

= 3,5 cc/jam
CONTOH PEMBERIAN DOPAMIN
BERAT BDAN/KG
DOSIS
40 kg 45 kg 50kg 55kg 60kg
2 mcg 1.2 cc 1.35 cc
3 mcg 1.6 cc 2.03 cc
4 mcg 2.4 cc 2.7 cc
5 mcg 3.0 cc 3.38 cc
6 mcg 3.6 cc 4.05 cc
7 mcg 4.2 cc 4.73 cc
8 mcg 4.8 cc 5.4 cc
9 mcg 5.4 cc 6.07 cc
Golongan Inotropik Positif
Sediaan Ampul 250 mg (5 cc)
Dosis 1 – 20 microgram/kgBB/menit
Pengenceran 250 mg/50 cc (1 cc = 5 mg = 5000
mikrogram)
Rumus Dosis x BB x menit
Pengenceran
 Dosis 5 microgram/kgBB/menit
 Berat Badan 67 kg.
 Berapa cc pengaturan syring Pump

5 micro x 67 kg x 60 menit
= 5000

= 4,02 cc/jam
Dobutamin
Pengenceran 500 mg/250 cc
 Dosis 5 mcg/kgBB/menit.
 Berat Badan: 70 kg
 Berapa cc pengaturan infus Pump/jam

Pengenceran 500 mg/250 cc (1 cc = 2 mg =

2000 mikrogram)
Rumus Dosis x BB x menit
Pengenceran
5 mcg x 70 kg x 60 menit
2000
Sumber: American Association of Critical-care Nurse, 2006
Silakan Hitung Pemberian
Dobutamin..........
 10 mcg/kgBB/menit
 Berat Badan 55 kg
 Berapa Seting Syring Pump..........????????
Golongan Anti angina (Vasodilator)
Sediaan Ampul 10 mg (10 cc)
Dosis Microgram/menit
Pengenceran 10 mg/50 cc ( 1cc = 0.2 mg = 200
microgram
50 mg/50 cc (1 cc = 1 mg = 1000
microgram)
Rumus Dosis x menit
pengenceran
 DOSIS PENGENCERAN
(Microgram) 10 mg/50 cc 50 mg/50 cc
5 1.5 cc 0.3 cc
10
15
20 6 cc 1.2 cc
25 7.5 cc
30 12 cc 1.8 cc
35
40 15 cc 2.4 cc
Pengenceran 10 mg/50 cc = 0.2 mg/1 cc

Dosis CC/jam Dosis CC/jam

0.2 mg 1 cc 2.2 mg 11 cc
0.4 mg 2 cc 2.4 mg 12 cc
0.6 mg 3 cc 2.6 mg 13 cc
0.8 mg 4 cc 2.8 mg 14 cc
1 mg 5 cc 3 mg 15 cc
1.2 mg 6 cc 3.2 mg 16 cc
1.4 mg 7 cc 3.4 mg 17 cc
1.6 mg 8 cc 3.6 mg 18 cc
1.8 mg 9 cc 3.8 mg 19 cc
2 mg 10 cc 4 mg 20 cc
Golongan Anti angina (Vasodilator)
Sediaan Ampul 10 mg (10 cc)
Dosis Microgram/menit
Pengenceran 10 mg/50 cc (1 cc = 0.2 mg = 200
microgram/cc)
Rumus Dosis x menit
pengenceran
Golongan Brochodilator
Sediaan Ampul 240 mg
Dosis 0.1 – 0.5 mg/kgBB/jam
Pengenceran 240 mg/50 cc ( 1 cc = 4.8 mg )

Rumus Dosis x BB x jam

pengenceran
Golongan Analgetik Narkotik
Sediaan Ampul 10 mg (1 mililiter)
Dosis 2 – 5 mg/jam
Pengenceran 10 mg/50 cc = 0.2 mg/cc
50 mg/50 cc = 1 mg/cc

Pemberian Morfin dengan pengenceran 10 mg/50 cc

Dosis (miligram) CC/jam Dosis (miligram) CC/jam
0,2 mg 1 cc 1,2 mg 6 cc
0.4 mg 2 cc 1.4 mg 7 cc
0.6 mg 3 cc 1.6 mg 8 cc
0.8 mg 4 cc 1.8 mg 9 cc
1 mg 5 cc 2 mg 10 cc

Pedoman American Association of Critical-care Nurse, 2006

Golongan Analgetik Narkotik
Sediaan Ampul 10 mg (1 mililiter)
Dosis 2 – 5 mg/jam
Pengenceran (NaCl 0.9%) 10 mg/50 cc = 0.2 mg/cc
50 mg/50 cc = 1 mg/cc

Pemberian Morfin dengan pengenceran 50 mg/50 cc

Dosis (miligram) CC/jam Dosis (miligram) CC/jam
1 mg 1 cc 6 mg 6 cc
2 mg 2 cc 7 mg 7 cc
3 mg 3 cc 8 mg 8 cc
4 mg 4 cc 9 mg 9 cc
5 mg 5 cc 10 mg 10 cc

Pedoman American Association of Critical-care Nurse, 2006

Dosis morfin (Latihan)
Dosis CC/jam Dosis CC/jam
(miligram) (miligram)
2,2 mg cc 3.8 mg
2.4 mg cc 4 mg
2.6 mg cc 4,2 mg
2.8 mg cc 4.4 mg
3 mg 15 cc 4.6 mg
3.2 mg 4.8 mg
3.4 mg 5 mg 25 cc
3,6 mg
Golongan inotropik
Sediaan Ampul 50 mg
Dosis Loding Dose 50 mcg/kgBB (infus > 10
menit)
Maintenence 0.375 – 0.75
mcg/kgBB/menit
Pengenceran 50 mg/250 cc = 0,2 mg/cc x 1000 =
(dextrose 5%) 200 mcg/cc
50 mg/ 50 cc = 1 mg/cc x 1000 = 1000
mcg/cc
Rumus Dosis x BB x menit
pengenceran

Pedoman American Association of Critical-care Nurse, 2006

Golongan Anti Aritmia
Sediaan Ampul 150 mg
Dosis Awal 150 - 300 mg
Pengenceran NaCL 300 mg/20 – 30 cc (Bolus Intra
atau Dex5% vena)

Dosis Ulangan 150 mg setelah 3-5 menit

(maksimal 2.2 gram/24 jam)
Golongan Beta adrenergik
Sediaan Ampul 4 mg Standar dilution:
Dextrose 5%.
Ampul 8 mg
Dosis Mulai 0.05 – 1 microgram
Pengenceran 4 mg/50 cc = 1 cc = 0.08 mg x
1000 = 80 microgram
8 mg/50 cc = 1 cc = 0.16 mg x
1000 mcg = 160 microgram
Rumus Dosis x BB x menit
pengenceran
Pedoman American Association of Critical-care Nurse, 2006

Sediaan Ampul 4 mg Standar dilution:

Dextrose 5%.
Ampul 8 mg
Dosis Mulai 2– 20 microgram/menit
Pengenceran 4 mg/50 cc = 1 cc = 0.08 mg x
1000 = 80 microgram
8 mg/50 cc = 1 cc = 0.16 mg x
1000 mcg = 160 microgram
Rumus Dosis x menit
pengenceran
Golongan Anti Hipertensi
Sediaan Ampul 10 mg
Dosis Mulai 0.05 microgram
Pengenceran/dilusi
NaCL 0.9% atau 10 mg/50 cc = 1 cc = 0.2 mg x
Dextrose 5%. 1000 = 200 microgram

Rumus Dosis x BB x menit

Pengenceran
Silakan hitung perdipine
 Dosis 0.05 mcg/kgBB/menit
 Berat Badan 40 kg
 Berapa seting syring pump.......
Golongan Diuretik
Sediaan Ampul 20 mg (2 cc)
Dosis 10 - 100 miligram/jam
Dosis contiyu: 1 mg/kg BB/jam
Tanpa • 25 ampul x 20 mg = 500
Pengenceran mg/50 cc
• 10 mg /1 cc
• 100 mg /10 cc
Dosis 100 mg/jam = 10 cc/jam