Symptom to Diagnosis: An Evidence-Based Guide, 4e >Approach to the Patient with Sore Throat - Case 1

Scott D.C. Stern, Adam S. Cifu, Diane Altkorn+

Table 30-1.Frequency and clinical syndrome for infectious causes of sore throat.

Class Infection Frequency1 Clinical Syndrome

Viruses Rhinovirus 20% Common cold

Coronavirus 5% Common cold

Adenovirus 5% Acute respiratory disease

HSV1 and 2 4% Stomatitis, pharyngitis

Influenza A and B 2% Influenza

Parainfluenza virus 2% Common cold, croup

EBV < 1% Infectious mononucleosis

CMV < 1% Infectious mononucleosis

HIV < 1% Primary HIV infection

Bacteria Group A beta-hemolytic streptococci 15–30% Pharyngitis, tonsillitis

Pharyngitis, peritonsillar abscess, Lemierre

Fusobacterium necrophorum 10%
syndrome (rare)

Group C beta-hemolytic streptococci 5% Pharyngitis, tonsillitis

Neisseria gonorrhoeae < 1% Pharyngitis

Corynebacterium diphtheriae < 1% Diphtheria

Mycoplasma pneumoniae < 1% Pneumonia, bronchitis

Chlamydophila pneumoniae Unknown Pneumonia, bronchitis

1Estimated percentage of cases in all ages, prevalence estimates are sensitive to the population studied.
CMV, cytomegalovirus; EBV, Epstein-Barr virus; HSV, herpes simplex virus.

Date of download: 06/21/23 from AccessMedicine: accessmedicine.mhmedical.com, Copyright © McGraw Hill. All rights reserved.