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  • Calon Descriptor Senyawa 48

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    Teguh Hidayat Panjaitan
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    5 views2 pages

    Calon Descriptor Senyawa 48

    Uploaded by

    Teguh Hidayat Panjaitan

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 2

    Calon descriptor

    1. SA
    2. Logp
    3. Massa
    4. Lumo
    5. DM

    Kombinasi

    kombinasi R
    SA , logp, massa 0.668
    SA, massa, lumo 0.662
    Massa, lumo, dm 0.723
    SA, lumo, dm 0.574
    LOGP, lumo, dm 0.564
    Lumo, logp, SA 0.563

    Persamaan

    Logc50 = -0.398 + (0.005*massa) + (-0.084*Lumo) – (-0.140*DM)

    = -0.398 + (0.005*229.25) + (-0.084*1.994569) – (-0.140*2.363)

    =0.911526204

    R = 0.975

    Fhit = 0.731

    Ftable = 19.1643

    Fhitung/Ftabel =6.367/19.164 = 0.0381438404

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