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Endocrine Diagnostic Tests
Endocrine Diagnostic Tests
THYROID DISORDERS
Thyroid Function Tests HIGH
Thyroid – Stimulating Hormone Assay Hypofunction of Thyroid Gland –
HYPOTHYROIDISM
LOW
Pituitary disorders -
HYPERTHYROIDISM
Radioactive Iodine Uptake (RAIU) HIGH Radioactive dose is small and harmless
Hyperthyroidism ; Urine: Contraindicated in pregnancy
Hypothyroidism Seasfoods my elevate the results
LOW Drugs can elevates the results: Barbiturates,
Hypothyroidism ; Urine; Estrogen, Phenothiazines
Hyperthyoidism
Dec. results: Lugol’s sl’n, SSKI, antithyroid,
cortisone, antihistamine
Collect 24 hr urine
Thyroid scanned after 24 hrs.
PARATHYROID DISORDERS
Total Serum Calcium Venous blood is collection
HIGH - Hyperparathyroidism
LOW- Hypoparathyroidism
ADRENOCORTICAL DISORDERS HIGH - Pituitary Tumor, CUSHING Give Dexamethasone before phlebotomy to suppress
Cortisol level with dexamethasone SYNDROME or DISEASE diurnal formation of ACTH.
suppression test LOW - ADDISON’S DISEASE
Cortisol Plasma Level HIGH- CUSHING DISEASE Fasting is required. the pt. should be on bed rest for 2
LOW- ADDISON’S DISEASE hrs. before the test bec. activity increases cortisol
level.
ADRENAL MEDULLARY
DISORDERS
TOTAL PLASMA The ct. should lie supine and rest for 30 mins
CATECHOLAMINE Butterfly needle is inserted 30 mins before blood
CONCENTRATION specimen collected.
NORMAL VALUES:
Epinephrine : 100 pg/ml (590 pmol/L)
Norepinephrine: 100 to 550 pg/ml (590-3240 pmol/L)
PANCREATIC DISORDERS
FBS (Fasting Blood Sugar); FBG DM - Inc. 140 mg/dL for 2 readings NORMAL VALUES :
(Fasting Blood Glucose) 70-110 mg/dL
Glycosylated Hgb Most accurate indicator of DM