Professional Documents
Culture Documents
Version #: 14
Issue date: 20-Jul-2018
Revision date: 22-Jun-2023
Supersedes date: 08-Mar-2023
Endocrine disrupting properties (Toxicity/Ecotoxicity): This mixture does not contain known
components considered to have endocrine disrupting properties according to REACH Article 57(f)
or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at
levels above possible trace contaminate levels.
Acute toxicity Based on available data, the classification criteria are not met.
Components Species Test Results
1,2-Benzisothiazolin-3-one (Benzisothiazolinone) (CAS 2634-33-5)
Acute
Dermal
LD50 Rat > 2000 mg/kg (OECD 402)
Oral
LD50 Mouse 1150 mg/kg
Rat 1020 mg/kg
670 mg/kg (OECD 401)
2,4,7,9-Tetramethyl-5-decyne-4,7-diol, ethoxylated (CAS 9014-85-1)
Acute
Inhalation
LC50 Rat 20 mg/l, 1 h Dusts, mists and fumes. The
data are derived from the evaluations or
test results achieved with similar products
(conclusion by analogy).
Oral
LD50 Rat 6300 mg/kg
2-Methyl-2h-isothiazol-3-one (Methylisothiazolinone) (CAS 2682-20-4)
Acute
Dermal
LD50 Rat 242 mg/kg (OECD 402)
Inhalation
LC50 Rat 0.11 mg/l, 4 h (OECD 403)
Oral
LD50 Rat 120 mg/kg
Skin corrosion/irritation Based on available data, the classification criteria are not met.
Irritation Corrosion - Skin
2-Methyl-2h-isothiazol-3-one (Methylisothiazolinone) Corrosive, rabbit (OECD 404)
1,2-Benzisothiazolin-3-one (Benzisothiazolinone) Irritating (4 h, rabbit)
2,4,7,9-Tetramethyl-5-decyne-4,7-diol, ethoxylated Not irritating, The data are derived from the evaluations or
test results achieved with similar products (conclusion by
analogy).
Test Duration: 24 h
Serious eye damage/eye Based on available data, the classification criteria are not met.
irritation
Eye
1,2-Benzisothiazolin-3-one (Benzisothiazolinone) Causes serious eye damage (rabbit)
2-Methyl-2h-isothiazol-3-one (Methylisothiazolinone) Corrosive, based on OECD 404 results
2,4,7,9-Tetramethyl-5-decyne-4,7-diol, ethoxylated Risk of serious damage to eyes, The data are derived from
the evaluations or test results achieved with similar products
(conclusion by analogy).
Species: Rabbit
Respiratory sensitization Based on available data, the classification criteria are not met.
Skin sensitization Non-sensitizer- Local Lymph Node Assay (OECD 429).
Sensitization
2,4,7,9-Tetramethyl-5-decyne-4,7-diol, ethoxylated May cause sensitization by skin contact.
Skin sensitization
1,2-Benzisothiazolin-3-one (Benzisothiazolinone) Causes sensitization (Guinea pig, OECD 406)
2-Methyl-2h-isothiazol-3-one (Methylisothiazolinone) Sensitzing, mice (OECD 429), Sensitzing, guinea pigs
(OECD 406)
Germ cell mutagenicity Based on available data, the classification criteria are not met.
Carcinogenicity Based on available data, the classification criteria are not met.
2,4,7,9-Tetramethyl-5-decyne-4,7-diol, ethoxylated Ames (OECD 471), Chromosomal aberration (OECD 473),
gene mutation (OECD 476), negative. The data are derived
from the evaluations or test results achieved with similar
products (conclusion by analogy).
Reproductive toxicity Based on available data, the classification criteria are not met.
Material name: 1CP98Series SDS SWITZERLAND
14208 Version #: 14 Revision date: 22-Jun-2023 Issue date: 20-Jul-2018 5 / 11
Specific target organ toxicity - Based on available data, the classification criteria are not met.
single exposure
Specific target organ toxicity - Based on available data, the classification criteria are not met.
repeated exposure
Aspiration hazard Based on available data, the classification criteria are not met.
Mixture versus substance Not available.
information
11.2. Information on other hazards
Endocrine disrupting (Toxicity): This mixture does not contain known components considered to have endocrine
properties disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU)
2017/2100 or Commission Regulation (EU) 2018/605 at levels above possible trace contaminate
levels.
Other information Complete toxicity data are not available for this specific formulation
Transport in bulk according to Annex II of MARPOL73/78 and the IBC code: Not applicable.
Other information This Safety Data Sheet complies with the requirements of Regulation (EU) 2015/830.
Classification according to Regulation (EC) No 1272/2008 as amended.
Specific Provisions: Regulation (EC) No 1907/2006 of the European Parliament and of the Council
concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH),
establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing
Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as
Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC
and 2000/21/EC (in the amended version OJ L 396 from 29.05.2007 page 3 with further
rectifications and amendments).
.
Switzerland VOC incentive tax - Contains >3% total VOCs but does not contain VOCs which are
subject for taxation.
National regulations Not available.
Switzerland. Schedules 1A-3B on Substances Subject to ChKV, Regulation on the Control of Chemicals with Civilian and
Military Use (ChKV)
Not listed.
15.2. Chemical safety See attached SUMI or GEIS document, if applicable.
assessment
Regulation (EC) No. 1272/2008 of December 16, 2008 on classification, labeling and packaging of
substances and mixtures, and amendments (CLP).
The information in this document is based on the present state of our knowledge, including but not
limited to the data present in the registrations of the ingredients, it does not purport to be
all-inclusive and shall be used only as a guide.
This Safety Data Sheet is in compliance with Commission Regulation (EU) 2020/878 of 18 June
2020 amending REACH Annex II.
Information on evaluation The classification for health and environmental hazards is derived by a combination of calculation
method leading to the methods and test data, if available.
classification of mixture
Full text of any statements,
which are not written out in full
under sections 2 to 15 H301 Toxic if swallowed.
H302 Harmful if swallowed.
H311 Toxic in contact with skin.
H314 Causes severe skin burns and eye damage.
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H330 Fatal if inhaled.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.
H411 Toxic to aquatic life with long lasting effects.
H412 Harmful to aquatic life with long lasting effects.
Revision information None.
Training information Follow training instructions when handling this material.
This safety data sheet is meant to convey information about HP inks (toners) provided in HP
Original ink (toner) supplies. If our Safety Data Sheet has been provided to you with a refilled,
remanufactured, compatible or other non-HP Original supply please be aware that the information
contained herein was not meant to convey information about such products and there could be
considerable differences from information in this document and the safety information for the
product you purchased. Please contact the seller of the refilled, remanufactured or compatible
supplies for applicable information, including information on personal protective equipment,
exposure risks and safe handling guidance. HP does not accept refilled, remanufactured or
compatible supplies in our recycling programs.