MULTIPLE SCLEROSIS MYASTHENIA GRAVIS GUILLIAN BARRE SYNDROME

DEMYELNATION DISORDER NEUROTRANSMITTER DISORDER: AUTOIMMUNE DISORDER

ACETYLCHOLINE (ACTH), DEMYELNATION DISORDER
AUTOIMMUNE DISORDER HX OF GI INFECTION (CAMPYLOBACTER
JEJUNI)
AFFECT CNS (BRAIN AND SPINAL CORD) AFFECT MUSCLE (EYES, THROAT LIMBS) AND AFFECT PERIPHERAL NERVES AFFECTS THE
MUSCLE STRENGTH FEET, HANDS AND LIMBS
DESCENDING PARALYSIS DOWN DESCENDING PARALYSIS DOWN ASCENDING PARALYSIS UP
EARLY SIGNS: DIPLOPIA SCOTOMA
VISUAL DISTURBANCE DIPLOPIA EARLY SIGNS: PTOSIS (DROOPING EYELID) EARLY SIGNS: LEG WEAKNESS, DYSKINESIA
SCHTOMA DYSPHAGIA RESPIRATORY DEPRESSION RESPIRATORY DEPRESSION
RESPIRATORY DEPRESSION OLIGURIA DYSPHAGIA CONSTIPATION DYSPHAGIA PALPITATION
OLIGURIA LOWER EXTM URINARY RETENSION CONSTIPATION
HALLMARK SIGN: SIN WEAKNESS
CHARCOTS TRIAD
SCANNING SPEECH HALLMARK SIGN: LATE SIGN: FACIAL PARALYSIS
INTENTIONAL TREMORS MUSCLE WEAKNESS BECOMES WORSE WITH
NYSTAGMUS ACTIVITY

LATE SIGN: ATAXIA (UNSTABLE GAIT)

MANAGEMENT: COMEPAN MANAGEMENT: MANAGEMENT:
CORTICOSTERIODS MECHVENT SAME WITH MS
O2 O2 ANTIBIOTICS
MECHVENT ASSIST ADL’S BETA BLOCKERS -olol
ENCOURAGE MUSCLE RELAXANT (BACLOFEN) NO TO MUSCLE RELAXANTS
PLASMEPHERESIS GIVE TIGMINE IN MORNING
ASSISTIVE DEVICE
NO TO HOT SPRING/HOT BATH/ HEATING PAD
DIAGNOSTIS TEST: DIAGNOSTIS TEST: DIAGNOSTIS TEST:
MRI, SPINAL TAP EDROPHONIUM TEST (TENSILON) CEREBROSPINAL FLUID ANALYSIS

MEDICATION: MEDICATION: ANTI-CHOLINESTERASE MEDICATION:

CORTICOSTERIODS NEOSTIGMINE PYRIDOSTIGMINE INTRAVENOUS IMMUNOGLOBULIN