Calculations-2 (Dilutions) 1, 400 mL of alcohol (95%) viv is added to 12% v/v solution of volume 1 L. What is the percentage of aleohol present in final solution? Answer: CIV] = C2V2 (400 mL) (0.95) + 1000 mL (0.12) = (1400) (X%) 380 + 120 = (1400 mL) (X%) 500 mL 400 mL x= 35.7% x 100 2, How many milliliters of water should be added to a pint (473 ml) of a 5% w/v solution to make a 2% w/v solution? Answer: QiCi = Q2C: 1 pin 73 ml 5% x 473 mL a= sR 2% This is total solution i.e. st + dilute solution, ml of water = 1182.5 ml ~ 473ml = 709.5 ml. = 1182 mL of total sol solution 3. How much water should be added to 150 mL of 95% ethanol to make 50% v/v ethanol? 4. How many mL of water should be added to 300 mL of 1:750 w/v solution of benzalkonium chloride to make 1:2500 w/v solution? 300 TAL 0 00 mL x 1+ 75 Sw = 1000 mL of total sol solution Answer = 1000 ml — 300 ml = 700 mL of water 5. You have alcohol 95% and an order requires preparation of 60 mL of alcohol 12%, How much of 95% alcohol should be used to make final solution. Dr Jaggi’s Aacdemy Page 1Calculations-2 (Dilutions) How much distilled water you take to prepare above prep? 60 mL — 7.57 mL = 52.5 mL water is added 6. A hospital requests 2 Ib of 2% hydrocortisone ointment. How many grams of 5% hydrocortisone ointment would be diluted with white petroleum to prepare this order? Ans: QC = QCe 1b = 454 g 2b = 908 g (908 g) (2%) = (x g) (5 %) p— 89x 2%) ~ 5% x= 363.2 7. How many mL of 0.9% (w/v) NaCl solution can be prepared from 250 mL of 25% (w/v) solution? Answer: QiC1 = Q2C> (x mL) 0.9% = (250 mL) (25 %) p — 250 mb x (25%) = 09% x = 6944.4 mL, 8. How many grams of 10% ammonia solution can be made from 1800 g of 28% strong ammonia solution? Answer: QACi= Cr (10%) X = (1800 g) (28 %) __ 1800 g x (28%) - 10 % x= 5040 g Dr Jaggi’s Aacdemy Page 2Calculations-2 (Dilutions) 9. 1f500 mL of a 15% v/v solution is diluted to 1500 mL, what is the resulting percentage strength? Ans: CX Vi C= ViCV V2 Cy = 200_mb x 15 % : 1,500 mE. X= 5% viv V2 10. What is the w/v concentration of a 1000 mL stock solution needed to prepare 4 L of 1:2000 solution? Ans 4.1L = 4000 mL 1:2000 = 0.05% CiV)=C2V2 (x) (1000 mL) = 0.05% (4000 mL) (0.2 %)(4000 mL) 1000 mL 11, One gallon (3785 ml) of a 30% w/v solution is concentrated by boiling to make a final solution of 50 % wiv. What is the final volume in milliliters (mL)? Tips: QC: = QC 3,785 (mL) x 30 (%) = x (mL) x 50(%) x 30% % 271 mL, Dr Jaggi’s Aacdemy Page 3