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    Frank Cordero
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    This document provides definitions and abbreviations for many terms related to multiple myeloma and epigenetic regulation. It defines abbreviations for things like types of leukemia, genes, cell lines, reagents, techniques, and epigenetic modifiers like histone modifiers and DNA methyltransferases. It also defines media components, buffers, antibodies, and other laboratory reagents commonly used in multiple myeloma and epigenetics research.

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    This document provides definitions and abbreviations for many terms related to multiple myeloma and epigenetic regulation. It defines abbreviations for things like types of leukemia, genes, cell lines, reagents, techniques, and epigenetic modifiers like histone modifiers and DNA methyltransferases. It also defines media components, buffers, antibodies, and other laboratory reagents commonly used in multiple myeloma and epigenetics research.

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    © All Rights Reserved
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    7 views3 pages

    Siglas

    Uploaded by

    Frank Cordero
    This document provides definitions and abbreviations for many terms related to multiple myeloma and epigenetic regulation. It defines abbreviations for things like types of leukemia, genes, cell lines, reagents, techniques, and epigenetic modifiers like histone modifiers and DNA methyltransferases. It also defines media components, buffers, antibodies, and other laboratory reagents commonly used in multiple myeloma and epigenetics research.

    Copyright:

    © All Rights Reserved
    Download as TXT, PDF, TXT or read online from Scribd
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    of 3

    AML - Acute myeloid leukemia

    E1A - Adenovirus early gene 1A


    BM - Bone marrow
    15q26 - Chromosome 15, location q26
    CLL - Chronic lymphocytic leukemia
    CML - Chronic myelogenous leukemia
    PC - Clonal plasma cells
    CpG - Cytosine-phosphodiester bound-guanine
    DNMTs - DNA methyltransferases enzymes
    FBS - Fetal Bovine Serum
    gDNA - Genomic DNA
    GLOBOCAN - Global Cancer Observatory
    H4 - Histone 4
    ALL - Acute lymphoblastic leukemia
    BFP - Lentiviral plasmid containing the reporter gene blue fluorescent protein
    MGUS - Monoclonal gammopathy of undetermined significance
    M protein - Monoclonal immunoglobulin
    MM - Multiple myeloma
    MDS - Myelodysplastic syndrome
    PCs - Normal plasma cells
    H3 - Histone 3
    sgRNA - Single guide RNA
    SMM - Smoldering myeloma
    US - United States
    CNVs - Various copy number variations
    CRISPR-Cas9 -clustered regularly interspaced short palindromic repeats and CRISPR-
    associated protein 9.
    RANK: receptor activator of NF-?B
    IgH- Inmunoglobulin heavy chain
    BSA- bovine serum albumin
    DMEM - Dulbecco�s modified Eagle�s medium DNA: deoxyribonucleic acid
    PBS- (Dulbecco's) phosphate-buffered saline
    PCR- polymerase chain reaction
    HATs-Histone acetyltransferases enzymes
    HDACs-histone deacetylases enzymes
    KMTs-Histone lysine methyltransferases
    H3K4me3-??trimethylation of H3 lysine 4
    H3K9me-trimethylation of histone H3 Lys9
    H3K27me2/3 - trimethylation of histone H3 Lys27
    gRNA-RNA guide
    BSA-Bicinchoninic acid
    SDS-PAGE-Sodium Dodecyl Sulphate-Polyacrylamide Gel Electrophoresis
    IgG-Inmunoglobulin G
    TRIzol-TRI Reagent)
    CRISPR
    CHD2
    PHF8
    CHD4
    ZMYND11
    RNA- ribonucleic acid
    CRISPR-Cas9
    CRAB- calcium elevation, renal insufficiency, anemia and bone abnormalities.
    IgH
    RAS
    KRAS
    NRAS BRAF
    TRAF3
    CYLD
    LTB
    DNA- deoxyribonucleic acid
    TP53
    ATMs
    ATR
    KDMs
    KMTs
    HDACs- histone deacerylases
    HATs-histone acetyltransferade
    UTX
    MLL
    MLL2
    ML3
    WHSC1
    HOXA9
    WHSC1
    IRF4
    PRDM1
    MYC
    BCL6
    PAX5
    IRF8
    gRNAs
    MM.1R-Cas9
    KMS-11-Cas9
    RPMI-1640
    HEPES
    HEK293T
    DMEM
    STR- short tadem repeat
    pHKO9-BFP
    PCR
    SOC
    RT
    BFP
    PBS
    cDNA
    GUSB
    MBTD1
    KMT2E
    MTRR
    PHF8
    PRMT2
    CHD2
    NSD2
    KAT2A
    KMT2D
    IKZF1
    EHMT2
    ASH1L
    CREBBP
    EZH2
    KMT2A
    ARID2
    CARM1
    ARID1A
    SETDB1
    BRPF1
    PRMT1
    SETD2
    PRMT5
    EP300
    IKZF3
    DNMT1
    DOT1L
    CHD4
    PHD
    ZNF422
    KIAA1111
    JHDMI
    ATP
    BS69
    PRKCBP1L1
    BRAM1
    MGC111056
    RP11-486H9
    EBNA
    BROMO
    NuRD- nucleosome remodeling and deacetylase
    ChAHP
    PAM- protospacer adjacent motif
    Bsmb
    HEK293T
    pHKO9-BFO
    KMS-11
    Cas9-2A-Blasticidin
    qPCR
    WB-western blot
    TET

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