CNS

1 Status epilepticus treatment

Benzodiazepines are the first-line treatment for convulsive status epilepticus because they
control seizures rapidly
For IV therapy, lorazepam is preferred in adults [6]; midazolam is preferred for
intramuscular (IM), intranasal or buccal therapy; and diazepam is preferred for rectal
administration.
Lorazepam – Use of lorazepam as a first-line agent

2 Amantadine MOA
Anti-Parkinson Agent inhibiting the N-methyl-D- aspartate (NMDA) type of glutamate receptors.

3 The dose of levodopa /carbidopa depend on which one of them?

Carbidopa

4 Mechanism of Action of chlorpromazine? N

Blockade of dopamine 2 receptors (D2) is responsible for reducing the positive signs of pyschosis
& improving other behaviors.
The combined effect to block D2, histamine H1 & muscarinic M1 receptors in the vomiting center is
postulated to reduce nausea & vomiting.
Blocks α-1 & 5-HT2 > D2 >D1.

5 Isoniazid is given with pyridoxine?

10 to 50 mg daily, to reduce the incidence of central nervous system (CNS) effects or
peripheral neuropathies.

6 Mechanism of donepezil in Alzheimer

reversible acetylcholinesterase (ache) inhibitor

7 Syncope from first dose ?

Prazosin

8 Lamotrigine side effect ?

Rash

9 Which one of antiepileptic drugs need renal adjustment ?

Topiramate

10 New drug for Alzheimer will be released so MOA will be?

inhibit B amyloid peptide

11
f
Patient obese has depression which antidepressant is best?
Buprobion

12 First line in status epileptic?

Lorazepam

13 Drug for severe Parkinson

14 Fastest anesthetic onset and recovery

Halothane
15 In which part of the brain dose Parkinson drugs make its effect
Therapy is aimed at restoring dopamine in the basal ganglia and antagonizing the
excitatory effect of cholinergic neurons, thus reestablishing the correct
dopamine/acetylcholine
Balance.

16 What is the medication to treat neuropathic pain and depression

The ADA guidelines recommend duloxetine and pregabalin first-line. Other drugs
That can be considered include tricyclic antidepressants (TCAs), gabapentin, venlafaxine,
carbamazepine, tramadol and topical capsaicin.

17 Pro drug primidone of ?

18
Phenobarbital
y
Phenytoin sodium equivalent to phenytoin base?
Each 100 mg of phenytoin sodium (salt) contain 92 mg of phenytoin base

19 Doctor prescribe phenytoin 100 mg TID and then change dose after how many days need
monitoring

0
30 days

20 Antidepressant should be avoided in seizures patient

Bupropion

21 Anxiolytic with least sedation and withdrawal symptoms

Buspirone
e
22 Analgesic considered as narcotic but dispensed normally
Methadone

23 Medications are common causes of both acute and chronic cognitive impairment
anticholinergic drug

24 Case of a female patient who is hypertensive and has a history of epileptic attacks and
recently she had depression? What is the best anti-depressant for her case
Paroxitine

25
as
Elder patient and fat and have depression what to give
Bupropion ( cause weight loss ) .

26
E
Hypertension and epileptic seizures have recently had a depression what is the best antidepressant
in its case
Paroxetine

27 old patient with seizure the physician prescribes diazepam what would you choose
Alprazolam

28 Drug of antiepileptic need to adjustment

Topromycine

To Biram Le
29 Treatment of eclampsia in seizures in woman
Magnesium sulfate
a
30 Side effect of benzodiazepines
Drowsiness and confusion are the most common side effects of the benzodiazepines.
Ataxia occurs at high doses Cognitive impairment

31 Antipsychotic treat the symptoms of schizophrenia

32 levodopa/carbidopa absorption affected by

empty stomach
Natalie pyridoxine
33 psychiatric patient use olanzapine - lab result high glucose Which alternative

Mr Ari piPra Zo l e
Haloperidol

34 What are the catecholamine

Epinephrine norepinephrine and dopamine

35 Smoking with olanzapine

This drug may cause somnolence and dizziness, if affected, avoid driving and operating
machinery. Avoid cigarette smoking

36 Clozapine monitoring
White blood cells

37 DOC absence seizures?

Ethosuximide.

38 Naloxone dose in children

As naloxone hydrochloride: 100-200 mcg, may give additional 100 mcg if necessary
at 2-3 minute intervals until adequate response is obtained
As naloxone hydrochloride: 10-20 mcg/kg at 2-3 minute intervals until adequate
response is obtained

39 Most effective medication in treating positive symptoms in schizophrenia

1st
2nd generation
X
40
g.e
tyramine when taken with MAOIs (monoamine oxidase inhibitor) cause severe crysis of.?
Hypertension

41 tertiary amine of TCA (tricyclic antidepressant) is ?

2udryiNostiptillihe dysPranihe
Amitriptylline and imipramine
42 Benzodiazepine is used in treatment of ?
( Anxiolytic and anticonvulsant ) anxiolytic

43 Child on oxcarbazepine for epilepsy and suffers from rash ?

Change to ethosuximide
a
45 ethosuximide ?
anti epileptic used in absence (petit mal) seizure

46 Drug of choice in absence seizures ?

Ethosuximide

47 Antidepressant helps in stop smoking ?

Bubropion

48 thiopental is ?
short acting barbiturates

49 Which of the following side effects is associated with the use of norepinephrine ?
Ischemic damage due to vasoconstriction and tissue hypoxia.

50 Ultra-short acting barbiturates are used primarily as ?

Preanesthetic agents

51 Which of the following drugs is not a Tricyclic Antidepressant?

Maprotiline (tetracyclic)

52 which one used to trigeminal neuralgia ?

tegretol(Carbamazepine)

53 used for alzehimer ?

Donepzil

54 which of these have interinsc sympathomemtices effect ?

Pindolol

55 antipsychotic cause agranulocytosis ?

clozapine atypical

56 amantadine(antiviral) used for ?

treatment of parkinsonism

57 fluoxetine is ?
SSRI(selective serotonin reuptake inhibitors)antidepressant

58 antibiotic which cause yellow teeth tetracycline ?

59 lorazepam is ?
hypnotic at dose of 4mg
60 anti cholinergic cause ?
Constipation

61 Which of the following drugs lead to addiction ?

Benzodiazepine

62 prodrug of phenobarbitone and Used as anti epileptic

Primidone

63 14years-obese girl comes to the clinic with severe rash. She was
initiated on oxcarbazepine about 3 weeks ago for management of partial
seizures.
Her medical history is significant only for seizures. She has recently
Become sexually active and admits to inconsistent contraceptive use.
Which one of the following interventions is best for her?
Change to topiramate

64 Carpidopa act anti-parkinsonism by .

inc. dopamine

65 Benzodiazipine indication ?
Anxiolytic

67 Which antidepressant drug that used with obese patient ?

Bupropion

68 Which antidepressant drug that used with seizure?

Sertraline

69 Patient with DM had ossessive depressive disorder what use

Paroxetine
Flu Vukan he
70 What is the drug of choice of obessive compulsive disorder ?
SSRI
Clomipramine or fluoxe3ne or fluvaxamaine

71 elderly using antidepressant and have high risk for fall this could linked to ?
Orthostatic hypotension