Page 1 of 10 Pharmacognosy Department-College of Pharmacy “TANTA UNIVERSITY FACULTY OF PHARMACY DEPARTMENT OF PHARMACOGNOSY ‘The exam consists of 2 Parts in 10 pages Part I. ‘0 MCQs (0.5 x 70 = 35 marks, 85 minutes). Part I ‘orrection and matehing (15 marks, 35 minutes). Answers outside specified places will be neglected. Use blue pen. Answers using pencilsPage 2 of 10 Pharmacognosy Department-College of Pharmacy PartI (35 marks, 85 minutes). You are provided with 70 MCQs. Select only one answer and mark your choice in answer sheet I in page 1 1- From Q. No. 1-48...... Essential oils (24 marks, 59 minutes) 2- From Q. No, 49-70.... Bitter principles, tannins and resins (11 marks, 26 minutes) 1-....... is perfumed fat obtained from flowers by cold or hot enfleurage. a- Conerete b- Absolute ¢- Spice d- Resinoid - Pomade 2- Essential oils of family Lauraceae are synthesized and accumulated in oil c a-True b- False 3. Rose Otto is prepared by ... method a Steam distillation b- Hydro diffusion ¢- Cohobation d- Ecuelle a piquer e- Sponge Match each sentence (Q 4-6) with only one suitable structure in List 1, +...4).... inhibits gastric and duodenal ulcers, )...i8 used for preparation of synthetic camphor. ~+-(6)....i8 colorless to white solid with camphor like odor. 7- a-Santalene is an example of .... Sesquiterpenes. a Monoeyelic b- Bicyclic © Tricy d- Acyclic e- Tetracyelic 8- Which of the following is the A!) p-menthadiene? a- Terpinolene b- Limonene &- ot terpinene d- Sylvestrene e- Myrcene 9 Azulenes are colored hydrocarbons included under monoterpenes. a-True b- False ion of volatile oils 10- Which of the following is the most suitable method for prepar: from fruits of family Rutaceae? a-Water distillation b-Water and steam distillation c- Expression -Direct steam distillation © Enflurage 11- Which of the following methods ean use wooden frames having glass plates covered with a layer of fat. The petals are spread across and pressed in? a-Ecuelle a piquer b- Pneumatic xpression d+ Maceration e- Enflurage 12 The most commonly used liquefied gas for supercritical fluid extraction is... aN: b-O2 ech d-CO2 eCOPage 3 of 10 Pharmacognosy Department-College of Pharmacy 13- Benzaldehyde can be obtained by hydrolysis of.. a-Sinigrin b- Amygdalin wae ‘od o- " Ce ». (12) ow by wD SS on 1d on an no on Comp. (11) os ee ‘eo Pa we We ° +0. Wo, wo We. Comp. (13) cu Q62) Q (53)Page 6 of 10 Pharmacognosy Department-College of Pharmacy 54-Tannins are classified into two groups depending on: a-The type of the phenolic nuclei b-The way the nuclei are linked The type of the sugar part d-Both a & b eBothb & ¢ 55-Phobaphenes are formed by heating ...... in strong a- Catechin type of condensed tannin b- Leucocyani c- Ellagitannin d- Gallitannin e-Botha&b type of condensed tannin Compounds 15-19 represent questions 56-60, choose the best answer from: a- A furanocoumarin ple and reduces Tollen’s reagent. bb Stimulant but carcinogenic and reduces Tollen’s reagent. ¢- Presents in equimolecular proportion with another compound and reacts with cone. H2SOz and vanillin/HC1. d- Used as sedative and as flavoring agent in brewing industry and reduces Tollen’s reagent. e- An insecticide that is extracted with CCly and decomposes in air and light into inactive acids. L 7 0“So. xt o ‘Comp. (15) 2 5 ‘OCs Comp. (17) ; Comp. (16) Ochs F Q 66) Q658) Q67) OCH; OCH o on Comp. (18) ‘Comp. (19) 69) R-OH (60) 61- Jalapin in Jalap resin is an example of: a- Resin acids b- Resin alcohols c- Resinotannols d- Resenes e- Glycoresins 62- Myrrh is an example of oleo-gum-resins. a- True b- False 63- It is the residue left after the di of various species of pinus. a- Canada Balsam b- Benzoin c= Copaiba + Guaiacum e- Colophony n of turpentine oil from the crude oleo-resinPage 7 of 10 Pharmacognosy Depariment-College of Pharmacy 64- Has anti-bilharzial and anti-schitosomal activities a- Asafoetida b- Gamboge c- Myrrh 4- Guaiacum e- Colophony 65- Toxic to tape worms (kills and expells the worms). a Myrrh b- Benzoin c- Copaiba d- Filixmas: e- Gamboge 66- Microscopical mountant a Canada Balsam. b- Benzoin &- Copaiba d- Balsam Tolu e- Colophony 67-Benzoin belongs to: a- Resins b- Balsams c- Gum-resins d- Oleo-gum-resin e- Resenes Match each sentence (Q 68-70) with only one suitable structure in List 4 -...(68)....i8 the main constituent of cannabis resin. ~ Etoposide (semisynthetic) from....(69)... is used in the treatment of cancer. ~-..(70)...i8 found in colophony. Lists on 9. OL = ym oY om aPage 8 of 10 Pharmacognosy Department-College of Pharmacy rt H (Ca QIl; you are provided with 15 sentences. Correct the underline word(s) at each sentence then match the corrected sentence with one suitable figure OR a related sentence from group I titled from (A-O). Please put your answers at answer sheet IT. rates) 15 point, 35 minut 1. D-cymarose is classified as sugar alcohol. 2. Uronic acid is a product of monosaccharide oxidation by conc. HNO3. 3. Meso-xyletol is used as acidulant in effervescent formulation. 4. Lactose is a disaccharide prepared by reaction of sucrose persulfate with aluminum hydroxide. 5. 4-0-8-D-mannopvranosyI-D-glactopyranose is defined as cellbiose, 6. Amylose is hydrolyzed by f-amylase enzyme to mannose and dext 7, Mmucilage is an acidic homopolysaceharides. 8, Lactulose is obtained by alkaline epimerization of sucrose. Gum arabie is a tetrasaccharide extracted from seeds of family Leguminosae. 10. Arabinans are homopolysaccharides terminated by a single D-glucose residue. 11. Agar is linear sulfated polysaccharides that are extracted from red seaweeds. 12, Gel filtration is used for determination of the configuration of the glvcosidic linkages in the polysaccharide molecules. 13. Glucomannan is a glycouronans used at food industry, as thickening and gelling agent. 14, Chemical dehydroxlation of chitin produces chitosan; a valuable industrial material used for water purification.Page 9 of 10 Pharmacognosy Department-College of Pharmacy H OH coo" H OH 4 H oH H OH H | On oH ©. | coo" H COO" c CH,OH eee OH OH Sa #80: C Oho: 2 oO H—;—_ OH NHg| NH CH,OH 2 E- CHOW c " 4 OT GHOH . CHO o. sy Ke | Rae on \* fag. au ‘i 4 ‘OH L 4 on OH Fr | G- it's a disaccharide hydrolyzed by the enzyme emulsion. H- it's a disaccharide used in treatment of stomach and duodenal ulcer. I- chromatography. | J- 2,6-dideoxy-3-o-methyL-D-allose, K- it react with I; forming a blue colored complex. L- itis consisting of two a-D-galactose units, one a-D-glucose unit, and one B-D-fructose unit sequentially linked. M- it'sa cathartic effect. Nc it is a semi-synthetic disaccharide, which reduces blood ammonia and used in the | symptomatic treatment of hepatic coma. O- mannosaccharic acid.Page 10 of 10 Answer sheet II Pharmacognosy Department-College of Pharmacy Corrected word Letter 10. 12 1B. 14. 15. Good luck