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Hepatitis B Blood Tests Explained

HBsAg Positive or Reactive

You have got Hepatitis B but this is usually a low risk or inactive level of infection and o!en le! untreated with anti viral's unless your liver tests
are abnormal. You will be advised to avoid alcohol, getting fat and certain medicines like paracetamol.
Anti-HBc IgM Positive or Reactive
You have a recent Hepatitis b Infection that your body is fighting. This fight usually lasts 6 months.
Anti-HBc IgG Positive or Reactive
You have had Hepatitis B for longer than 6 months and the infection is now lasting or chronic.
Anti HBs Positive or Reactive
You had Hepatitis B in the past and have cleared it from your system and now have antibodies that keep you immune and safe from any future
infection of Hepatitis B. Or you have been immunised/vaccinated for Hepatitis B at some point.
HBeAb Positive or Reactive
You had Hepatitis B but cleared the part that makes the virus increase to very high amounts. Most patients clear the HBeAg or e antigen part of
Hepatitis B in the first 6 months, but some do not clear the HBsAg or surface antigen.
HBeAg Positive or Reactive
You have got Hepatitis B and it is able to increase quickly in amount (o!en high risk yet quickly manageable with anti viral's such as Tenofovir)
HBV DNA (high)
You have got Hepatitis B and it is high in amount (o!en high risk yet quickly manageable with anti viral's such as Tenofovir)

When a full set of HBV tests are done it allows us to understand if we are Chronically or Acutely infected, whether the infection is active or
inactive and whether we are immune to infection or susceptible to infection.

Hepatitis B Blood Test Chart

Test results come with all aspects tested including out e and s antigens and antibodies and our core antibodies, together the combinations
below define our Hepatitis B status. The vast bulk of the "Result Unclear category at the bottom have tended to be cleared and harmless old
infections, not small actual infections, so do not panic if the unclear result is yours.

HBsAg negative Susceptible

anti-HBc negative
anti-HBs negative

HBsAg negative Immuneduetonaturalinfection

anti-HBc positive
anti-HBs positive

HBsAg negative ImmuneduetohepatitisBvaccination

anti-HBc negative
anti-HBs positive

HBsAg positive Acutelyinfected

anti-HBc positive
IqManti-HBC positive
anti-Bs negative

HBsAg positive Chronicallyinfected

anti-HBC positive
IgManti-HBc negative
anti-HBs negative

HBsAg negativeInterpretationunclear;fourpossibilities:
anti-HBc positive 1.Resolvedinfection(mostcommon)
anti-HBs negative 2.False-positiveanti-HBc,thussusceptible
3."Lowlevel"chronicinfection
4.Resolvingacuteinfection

Email coordinator@hepb.org.uk Address: Unit B 35 Romney Road Hayes Middlesex UB4 8PU Freephone Confidential Helpline: 07958 558510

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