Dept. Biokimia FKIK UNIB Deficiency • Rickets (children and adolescent). • Osteomalacia (adults). • There is growing evidence that higher vitamin D status is protective against various cancers (inc. prostate and colorectal), and also against prediabetes and the metabolic syndrome. • Desirable levels of intake may be considerably higher than current reference intakes, and certainly could not be met from unfortified foods. • Essential for prevention and treatment of osteomalacia in the elderly. • Less evidence that it is beneficial in treating osteoporosis. TERIMA KASIH