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IOVS Papers in Press. Published on December 16, 2014 as Manuscript iovs.

14-14934

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TN64 reduces the proliferation of lens epithelial cells without significantly affecting the cell

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The scFv TN64 has an inhibitory effect on the migration of lens epithelial cells:

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scFv TN64 leads to decrease in expression of matrix metalloproteases:

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TN64 causes changes in actin stress fiber formation:

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Fibronectin polymerization is significantly decreased in the presence of TN64:

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TN64 causes marked reduction in expression of other markers of epithelial-mesenchymal

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Blocking of TNfnIII 1-5 using TN64 causes altered localization of ȕ-catenin:

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TN64 operates through inhibition of the non-canonical signaling pathways

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