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She is suffering ... And mailing you a nickel won’t help. Some groups will glue a nickel to their letters to get your attention At PCRM, we'd rather USE that nickel to save a dog like Queenie .. we think you would, too Dear Friend, With a name like Queenie, you"d think this sweet Dalmatian mix with hopeful eyes ‘might have a pampered life. But her life was nothing short of torture. Queenie was sold to a university laboratory that performs cruel, unnecessary experiments on live animals. In the lab, Queenie and countless other healthy dogs were cut open, devices were implanted into their hearts and blood vessels, and then they were forced to run on treadmills Her face and paws swelled. She whined, she vomited, and fluids leaked from her wounds, Did they stop to save this poor dog from pain? No, Instead they forced her to run the treadmill again, ‘Then they induced hypertension in Queenie by reducing the flow of blood to her kidneys. It was noted that she was “acting very timid ... shakes while getting up ... won't get up for me.” But that same day, they still made her run, Even after Queenie’ leg gat caught in the treadmill. she was forced ton injured, Aiptocing and limping as best she could. Then, aftec nine torturous months in their “care.” they Killed her. Asa physician, as a human being, Lam appalled by stories like Queenie’s. Using and abusing innocent animals in the name of seience or education is just plain wrong ~ especially since there are superior, readily available nonanimal alternatives. Don’t you agree? ‘Then please join me today. The Physicians Commitee for Responsible Medicine (PCRM) is doing everything in our power to stop the use and abuse of animals in medical school, corporate, and hospital laboratories nationwide You can help by mailing your tax-deduetible donation of $20 or more right away. We'll put your gift to immediate use in all of our lifesaving work. ‘And please sign and return the enclosed petition to the National Institutes of Health (NIH). They've been funding experiment that Killed Queenie with millions of dollars (over, please) 5100 WISCONSIN AVE., N.W., STE, 400 + WASHINGTON, DC 20016-4131 + WWW.PCRM.ORG @ bechiPew Page Two We urgently need more compassionate people like you to join us ~ and speak on behalf of animals like Queenie, who cannot speak for themselves. 1 promise that your support today will make a difference ~ and we have the track record to prove it. Since I founded PCRM 27 years ago, our campaign to end the use of live animal Jabs in medical schools has convinced more than 95 percent of schools to stop using animals. One of our earliest victories was when we persuaded the University of California, San Diego School of Medicine to stop training practices that had students performing invasive procedures on live dogs. Before PCRM intervened, dogs were used in six-hour teaching exercises, and then disposed of once the class ended. You can imagine how many dogs were needlessly killed ‘And when PCRM learned that live pigs were being used at the University of Wisconsin ‘School of Medicine and Public Health, we jumped into action, First-year medical students at this school performed invasive procedures on live pigs, including opening the animals’ chest cavities, before they were bled out. Thanks to our efforts, animals are no longer being used. And this past summer, PCRM made stunning progress, convincing six more medical centers to stop using cats — in some cases even kittens — or ferrels to teach endotracheal ‘intubation to pediatris residents. Atthese medical centers, future pediatricians would force plastic tubes down the airways of these poor animals ~ as often as 22 times a day ~ even though the anatomical differences between animals and human babies render this type of training ineffective. The kittens risked suffering tracheal bruising, bleeding, scarring, airway swelling, and severe pain. ‘What makes their suffering even more senseless is that there are state-of-the-art medical simulators based on human anatomy that are much more effective in teaching intubation methods, It took the persistence of PCRM and our team-building approach that rallies support from concerned citizens like you, as well as the medical community, to finally convince ‘these medical centers to embrace this new technology and stop needlessly abusing kittens, Years of hard work go into every PCRM campaign — and we depend on people like you. to help us win, People like you, who agree that inflicting pain on animals cannot be tolerated any longer. It's simply unconscionable, Let me give you a better idea of how we work to save animals in medical school labs. First we take a collaborative approach, We meet with the instructors teaching ive animal (next page, please) Page Three labs and educate them about nonanimal teaching methods, including medical simulators that make animal abuse in laboratories obsolete. ‘We encourage them to respond to student pressure calling for an end to cruelty in their courses —and listen to physicians and residents who want their campus labs to be free of abused animals, If collaboration doesn’t work, PCRM tums up the heat ‘We contact department chairs and school administrators and attempt to arrange high-level meetings to make our case against animal use. And we start mobilizing community support ~ including support from local physicians ~ with signs, billboards, door-to-door ‘campaigning, and press conferences. Nationally, PCRM reaches out for help via-mail, e-meil, and social media. his is where grassroots support, like your real difference. 1ed petition tothe. Asa last resort, PCRM takes legal action against medical schools that have resisted all effort to stop their live animal labs ~ on the grounds that this heinous practice violates the federal Animal Welfare Act, ‘Our unique approach works. Most of the nation’s leading medical schools ~ like Yale, Columbia, and Stanford — have stopped using live animals. Yet there are still five U.S. medical schools using live animals. And PCRM will not 4quit this campaign until the last school complies with the federal Animal Welfare Act. The remaining schools have dug in their heels. And they have the finances to carry this fight forward So PCRM must rally support from caring people like you, Will you stand with us inthis effort by sending your donation of $20 or more? Together ‘we can free innocent animals who are right now being needlessly injected, cut, mutilated, and killed .. just like Queenie. ‘Your donation will also help CRM demonstrate to chemical and pharmaceutical ‘companies that they can reduce and even eliminate the number of animals they use in toxicity testing... speak out against public health risks posed by unethical research ... and promote nutrition policies and practices that are healthier for our society and save animals’ lives. Together we can open the eyes of universities reluctant to change their ways. We can stand up against well-hecled special interests and corporations. Ve can prove that compassion ‘wins out over cruelty, and that justice wins out even for animals helpless to defend themselves. (over, please) Page Four He can ~ but only if you stand together with PCRM against those who would hide behind the cloak of “research” and brutalize animals when there are better, more humane ‘options available, Animals like Queenie deserve compassion. They ache for gentleness, kindness — any reason to wag their tals. They ask for so litle and they offer so much in return, Please help us help them. I know many organizations feel they have to glue nickels to their letters to persuade you to Join their cause. But I believe that people who want to truly make a difference would rather see that nickel put toward saving lives ... ands a PCRM supporter, you will know your donation is being spent wisely: So please send in your donation of $20 or more today. We are so close to winning. Yet there are still animals locked in laboratories whose every waking moment is spent in fear, waiting for the next round of unconscionable torture. ‘We are too late for Queenie, But we are not too late for thousands of animals like her Please let me hear from you soon. Sincerely, MetbhamnaD Neal D. Bamard, M.D. President PS. If we can pressure the NIH to cut off funding for unconscionable experiments like the cones that tortured Queenie, lives will be saved. So, please, urge you to sign the enclosed petition and rush it back to me with your generous contribution today! JOIN PCRM TODAY! &H YESEI wane to join others from Philadelphia to help PCRM save more innocene animals and improve the health of people by supporting all of PCRM's vital programs. Enclosed is my gift of G10 G$20 Cs35 $50 $100 C Your Best Gift $_ Please make your check payable to PERM and rerun ie with this form in the nvclope enclosed, For rei ad gis, please sc revere. Your contin sexed a allowed byl. And don’ forge to sign the attache petition! Thank you! 1 Please send me campaign upsaces and the PCRM Online os ‘monthly enevslcer. My email addres is (GBB Spring Garden St FL. mR Philadelphia PA 19130- SS Mu a eo crs20028E (Pea sign and return the pstition below with your consibution, Do not detach) Francis Collins, M.D, Ph.D. Director ‘National Institutes of Health Re: Use of Dogs in Heart Failure Research [am writing to ask chat the National Institutes of Health withdraw millions of dollars in funding fom university research luring which devices are surgically implanted in dogs before forcing the animals to ran on treadmills. Please end these cruel experiments by withdrawing funding immediately. Sincerely, Chris Smith Philadelphia, PA PHYSICIANS COMMITTEE FOR RESPONSIBLE MEDICINE 5100 WISCONSIN AVE, NW, STE. 400 WASHINGTON, OC 20016-4131 | WWW.PCRM.ORG + 202-686-2210 visa CD vusTERCARD O AMEX O OSCOVER 5 ca NER Sane ON can EMAL ORES Wie se for szurate rspece and forme comico Iryou woud te to mod your aig preferences, pease eal ws acimambersipQPCRM org cape at Fete ht Ph Sceaerstig cen eaten cia LA, Mtn ere ost psa ring. te Seay of Se. Mtg: HHS No. dese cae cae ieee nace aneucanae caren, anu eter Seater cue asonen Naa tae a ae aE Fh ny Ss tate er a ene Sooo ee eeu etc mere cy wa iigane ter anrts beiheona ae cea ea Siermcrsmaat orm tema aa ena CONTRIBUTIONS ARE DEDUCTIBLE FOR FEDERAL INCOME TAX PURPOSES IN ACCORDANCE APPROVAL, OR RECOMMENDATION OF PCRM BY THE STATE, “ A Nickel? Or a Life? A lot of organizations are sending nickels to people like you to try to persuade you to read their letters But nickels add up ~ and we'd rather spend that money to save animals like Queenie, who spent nine torturous months in constant fear and pain at a university laboratory When you make your tax-deductible donation to PCRM, you can rest assured that your gift will be used to spare animals from pain, suffering and cruelty, and support all our vital programs ay Ne Le. Hil my signed att cave aia BUSINESS A MAIL Physicians Committee for Responsible Medicine P.O. Box 96736 Washington, D.C. 20077-7541 ee AAD b Adel ts ben taal! eta hh FIVE WAYS TO HELP STOP ANIMAL CRUELTY 1. Support charities that don’t fund animal experiments. The over-reliance on this ineffective method has led to delays and dead ends in medical disease research. 2. Try a new healthy vegetarian recipe once a week. The animals and your body will thank you. 3. Write to your local high school principal and let him or her know that there are cffective cruelty-free alternatives to dissection to teach anatomy in biology classes Learn more at www.DissectionAlternatives.com. 4. Sign the enclosed petit 5. Become a PCRM Member today!

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