Test Bank for Pharmacology 7th Edition by Hitner

Test Bank for Pharmacology 7th Edition by Hitner

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 Chapter 009 Skeletal Muscle Relaxants

Multiple Choice Questions

1. The major toxicity associated with neuromuscular blocker overdose is:

A. Respiratory muscle paralysis
B. Cardiovascular collapse
C. Hypercalcemia
D. Hyponatremia

2. What is the drug of choice for treating malignant hyperthermia?

A. Tizanidine
B. Dantrolene
C. Baclofen
D. Diazepam

3. The antidote given for depolarizing muscle blocker toxicity is:

A. Pancuronium
B. Succinylcholine
C. Anticholinesterase drug
D. None available

4. Two types of receptors that can be manipulated to reduce spasticity are:

A. Alpha-1 adrenergic and GABA
B. Serotonin and GABA
C. Histamine and cholinergic
D. Alpha-2 adrenergic and GABA

5. Which type of skeletal muscle relaxant can be considered a cholinergic receptor

antagonist?
A. Nondepolarizing
B. Depolarizing
C. Direct acting
D. Indirect acting

9-1
 Chapter 009 Skeletal Muscle Relaxants

6. Some patients may have a genetic predisposition to developing malignant hyperthermia

when taking an inhalation anesthetic with which type of skeletal muscle relaxant?
A. Pancuronium
B. Succinylcholine
C. Dantrolene
D. Baclofen

7. Prolonged use of which centrally acting skeletal muscle relaxant can lead to dependency?
A. Baclofen
B. Methocarbamol
C. Diazepam
D. Orphenadrine

8. Dantrolene relaxes muscle by inhibiting the release of which ion from the sarcoplasmic
reticulum?
A. Sodium
B. Chloride
C. Potassium
D. Calcium

9. What category of muscle relaxants would be ideal for a patient needing intubation?
A. Depolarizing
B. Nondepolarizing
C. Direct acting
D. Centrally acting

10. Which of the following should be taken into consideration when selecting a
neuromuscular blocking drug for surgical relaxation?
A. Duration of action
B. Time of onset
C. Reversibility
D. All of these are correct.

9-2
 Chapter 009 Skeletal Muscle Relaxants

11. Discontinuation of intrathecal baclofen therapy should be gradual in order to prevent:

A. Severe hypotension
B. Hyperglycemia
C. Rebound spasticity
D. Hypernatremia

12. A patient with breathing problems has been given a muscle relaxant and begins to
experience bronchospasms, which may lead to an asthmatic attack. This can be attributed to
the release of:
A. Acetylcholine
B. Norepinephrine
C. Serotonin
D. Histamine

13. Which of the following would be observed from a low dose of a nondepolarizing muscle
relaxant used to promote a neuromuscular blockade?
A. Relaxation of facial muscles
B. Relaxation of arms and legs
C. Relaxation of trunk muscles
D. Relaxation of diaphragm

14. The duration of action of many nondepolarizing skeletal muscle relaxants will differ
according to which pharmacokinetics property?
A. Excretion
B. Metabolism
C. Absorption
D. Distribution

9-3
 Chapter 009 Skeletal Muscle Relaxants

15. A medication that results in spinal hyperpolarization would belong to which class of
skeletal muscle relaxants?
A. Nondepolarizing
B. Depolarizing
C. Centrally acting
D. Direct acting

16. Tranquilizers activate GABA receptors by causing ___ ions to move ___ the cell.
A. Potassium, outside
B. Sodium, inside
C. Chloride, outside
D. Chloride, inside

17. Peripheral skeletal muscle relaxation can be achieved by using which medications?
A. Dantrolene and pancuronium
B. Baclofen and dantrolene
C. Pancuronium and succinylcholine
D. Baclofen and diazepam

18. One way to overcome the effects of a rapidly metabolized skeletal muscle relaxant is to
administer the medication by:
A. IV injection
B. IV infusion
C. IM injection
D. Subcutaneous injection

19. A patient with a spinal cord injury would be treated best with which muscle relaxant?
A. Succinylcholine
B. Dantrolene
C. Baclofen
D. Mevacurium

9-4
 Chapter 009 Skeletal Muscle Relaxants

20. Which medication can potentiate the effects of succinylcholine due to shifting the levels
of potassium in the body?
A. Narcotics
B. NSAIDs
C. Antiemetics
D. Diuretics

9-5
 Chapter 009 Skeletal Muscle Relaxants Key

Multiple Choice Questions

1. (p. 120) The major toxicity associated with neuromuscular blocker overdose is:
A. Respiratory muscle paralysis
B. Cardiovascular collapse
C. Hypercalcemia
D. Hyponatremia

The major toxicity associated with all neuromuscular blockers is paralysis of the respiratory
muscles.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Remembering
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Easy
Learning Outcome: 9.3 Examine how these drugs may alter the ability to control respiration.

2. (p. 122) What is the drug of choice for treating malignant hyperthermia?
A. Tizanidine
B. Dantrolene
C. Baclofen
D. Diazepam

Dantrolene is used in the treatment of malignant hyperthermia and spastic conditions.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Remembering
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Easy
Learning Outcome: 9.6 List three potential adverse effects associated with muscle relaxants.

9-6
 Chapter 009 Skeletal Muscle Relaxants Key

3. (p. 120) The antidote given for depolarizing muscle blocker toxicity is:
A. Pancuronium
B. Succinylcholine
C. Anticholinesterase drug
D. None available

There is no known antidote that reverses the neuromuscular blockade produced by

succinylcholine.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Understanding
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Easy
Learning Outcome: 9.3 Examine how these drugs may alter the ability to control respiration.

4. (p. 123) Two types of receptors that can be manipulated to reduce spasticity are:
A. Alpha-1 adrenergic and GABA
B. Serotonin and GABA
C. Histamine and cholinergic
D. Alpha-2 adrenergic and GABA

Benzodiazepines and baclofen bind with GABAA and GABAB receptors, respectively, and
cause chloride ions (ClS, negative ion) to move across the membrane into the cells, making
the membrane hyperpolarized (can't respond to stimulation). Through a different mechanism
of action, tizanidine (Zanaflex) reduces spasticity by interacting with alpha-2 adrenergic
receptors in the CNS.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Understanding
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Easy
Learning Outcome: 9.4 Explain how tranquilizers relax skeletal muscles through a different mechanism of action than nondepolarizing
blockers

9-7
 Chapter 009 Skeletal Muscle Relaxants Key

5. (p. 118) Which type of skeletal muscle relaxant can be considered a cholinergic receptor
antagonist?
A. Nondepolarizing
B. Depolarizing
C. Direct acting
D. Indirect acting

The nondepolarizing blockers combine with the nicotinic-muscle receptors but do not
stimulate the receptors.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Understanding
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Easy
Learning Outcome: 9.1 Describe at least two ways in which skeletal muscle may be relaxed.

6. (p. 120) Some patients may have a genetic predisposition to developing malignant
hyperthermia when taking an inhalation anesthetic with which type of skeletal muscle
relaxant?
A. Pancuronium
B. Succinylcholine
C. Dantrolene
D. Baclofen

Occasionally, a normal dose of succinylcholine in combination with an inhalation anesthetic

produces a condition known as malignant hyperthermia.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Understanding
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Easy
Learning Outcome: 9.6 List three potential adverse effects associated with muscle relaxants.

9-8
 Chapter 009 Skeletal Muscle Relaxants Key

7. (p. 124) Prolonged use of which centrally acting skeletal muscle relaxant can lead to
dependency?
A. Baclofen
B. Methocarbamol
C. Diazepam
D. Orphenadrine

Prolonged use of diazepam and chlordiazepoxide may lead to dependency.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Applying
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Medium
Learning Outcome: 9.4 Explain how tranquilizers relax skeletal muscles through a different mechanism of action than nondepolarizing
blockers

8. (p. 122) Dantrolene relaxes muscle by inhibiting the release of which ion from the
sarcoplasmic reticulum?
A. Sodium
B. Chloride
C. Potassium
D. Calcium

By interacting with specialized receptors (ryanodine receptor channel) in the sarcoplasmic

reticulum, dantrolene blocks the release of calcium ions.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Applying
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Medium
Learning Outcome: 9.1 Describe at least two ways in which skeletal muscle may be relaxed.

9-9
 Chapter 009 Skeletal Muscle Relaxants Key

9. (p. 125) What category of muscle relaxants would be ideal for a patient needing intubation?
A. Depolarizing
B. Nondepolarizing
C. Direct acting
D. Centrally acting

None of the nondepolarizing blocking drugs equals the rapid onset and short duration of
action of succinylcholine (Anectine).

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Applying
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Medium
Learning Outcome: 9.2 Explain why muscle relaxation is necessary during diagnostic and surgical procedures.

10. (p. 125) Which of the following should be taken into consideration when selecting a
neuromuscular blocking drug for surgical relaxation?
A. Duration of action
B. Time of onset
C. Reversibility
D. All of these are correct.

The selection of a neuromuscular blocking drug for surgery depends on the time of onset and
the duration, adverse effects, and reversibility (ability to remove the NMJ blockade) of the
drug; the duration of the surgery; and the specific condition (weight, medical history, current
conditions) of the patient.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Applying
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Medium
Learning Outcome: 9.2 Explain why muscle relaxation is necessary during diagnostic and surgical procedures.

9-10
 Chapter 009 Skeletal Muscle Relaxants Key

11. (p. 124) Discontinuation of intrathecal baclofen therapy should be gradual in order to
prevent:
A. Severe hypotension
B. Hyperglycemia
C. Rebound spasticity
D. Hypernatremia

Abrupt discontinuation of intrathecal baclofen infusion has resulted in muscle rigidity,

rebound spasticity, and, in some cases, organ failure and death.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Applying
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Medium
Learning Outcome: 9.5 Identify which drugs are used in the chronic treatment of spastic muscle disorders.

12. (p. 120) A patient with breathing problems has been given a muscle relaxant and begins to
experience bronchospasms, which may lead to an asthmatic attack. This can be attributed to
the release of:
A. Acetylcholine
B. Norepinephrine
C. Serotonin
D. Histamine

Some of the blockers (atracurium, mivacurium, succinylcholine) cause a release of histamine

from mast cells, which can lead to the production of bronchospasms and increased bronchial
secretions in sensitive patients.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Applying
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Medium
Learning Outcome: 9.6 List three potential adverse effects associated with muscle relaxants.

9-11
 Chapter 009 Skeletal Muscle Relaxants Key

13. (p. 119) Which of the following would be observed from a low dose of a nondepolarizing
muscle relaxant used to promote a neuromuscular blockade?
A. Relaxation of facial muscles
B. Relaxation of arms and legs
C. Relaxation of trunk muscles
D. Relaxation of diaphragm

The muscles of the eyes and face are the first to become relaxed, followed by the limbs, trunk,
and diaphragm.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Analyzing
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Hard
Learning Outcome: 9.3 Examine how these drugs may alter the ability to control respiration.

14. (p. 119) The duration of action of many nondepolarizing skeletal muscle relaxants will differ
according to which pharmacokinetics property?
A. Excretion
B. Metabolism
C. Absorption
D. Distribution

The duration of action, therefore, varies with the type of metabolism the drug undergoes.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Analyzing
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Hard
Learning Outcome: 9.3 Examine how these drugs may alter the ability to control respiration.

9-12
 Chapter 009 Skeletal Muscle Relaxants Key

15. (p. 123) A medication that results in spinal hyperpolarization would belong to which class of
skeletal muscle relaxants?
A. Nondepolarizing
B. Depolarizing
C. Centrally acting
D. Direct acting

Benzodiazepines and baclofen bind with GABAA and GABAB receptors, respectively, and
cause chloride ions (Cl–, negative ion) to move across the membrane into the cells, making the
membrane hyperpolarized (can't respond to stimulation).

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Analyzing
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Hard
Learning Outcome: 9.4 Explain how tranquilizers relax skeletal muscles through a different mechanism of action than nondepolarizing
blockers.

16. (p. 123) Tranquilizers activate GABA receptors by causing ___ ions to move ___ the cell.
A. Potassium, outside
B. Sodium, inside
C. Chloride, outside
D. Chloride, inside

Benzodiazepines and baclofen bind with GABAA and GABAB receptors, respectively, and
cause chloride ions (Cl–, negative ion) to move across the membrane into the cells, making the
membrane hyperpolarized (can't respond to stimulation).

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Analyzing
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Hard
Learning Outcome: 9.4 Explain how tranquilizers relax skeletal muscles through a different mechanism of action than nondepolarizing
blockers.

9-13
 Chapter 009 Skeletal Muscle Relaxants Key

17. (p. 117) Peripheral skeletal muscle relaxation can be achieved by using which medications?
A. Dantrolene and pancuronium
B. Baclofen and dantrolene
C. Pancuronium and succinylcholine
D. Baclofen and diazepam

In contrast, peripheral skeletal muscle relaxants inhibit muscle contraction at the NMJ or
within the contractile process.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Analyzing
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Hard
Learning Outcome: 9.1 Describe at least two ways in which skeletal muscle may be relaxed.

18. (p. 119) One way to overcome the effects of a rapidly metabolized skeletal muscle relaxant is
to administer the medication by:
A. IV injection
B. IV infusion
C. IM injection
D. Subcutaneous injection

The depolarizing blocker succinylcholine is metabolized so rapidly that it is often

administered by intravenous infusion to maintain skeletal muscle relaxation.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Analyzing
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Hard
Learning Outcome: 9.1 Describe at least two ways in which skeletal muscle may be relaxed.

9-14
Test Bank for Pharmacology 7th Edition by Hitner

Chapter 009 Skeletal Muscle Relaxants Key

19. (p. 123) A patient with a spinal cord injury would be treated best with which muscle
relaxant?
A. Succinylcholine
B. Dantrolene
C. Baclofen
D. Mevacurium

Baclofen is primarily used to relieve the symptoms of spasticity (flexor spasms, clonus,
muscle rigidity) in patients with multiple sclerosis but also may be of value in patients with
spinal cord injury resulting in severe spasticity.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Analyzing
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Hard
Learning Outcome: 9.5 Identify which drugs are used in the chronic treatment of spastic muscle disorders.

20. (p. 121) Which medication can potentiate the effects of succinylcholine due to shifting the
levels of potassium in the body?
A. Narcotics
B. NSAIDs
C. Antiemetics
D. Diuretics

Succinylcholine-induced neuromuscular blockade is potentiated by drugs that promote a loss

of potassium, such as diuretics and digitalis.

ABHES Competency: 2. Anatomy and Physiology b. Identify and apply the knowledge of all body systems; their structure and functions; and
their common diseases, symptoms, and etiologies. c. Assist the physician with the regimen of diagnostic and treatment modalities as they
relate to each body system. 6. Pharmacology b. Properly utilize PDR, drug handbook, and other drug references to identify a drug's
classification, usual dosage, usual side effects, and contraindications.
Bloom's: Analyzing
CAAHEP Competency: I. Anatomy and Physiology 11. Identify the classifications of medications, including desired effects, side effects, and
adverse reactions. 12. Describe the relationship between anatomy and physiology of all body systems and medications used for treatment in
each.
Difficulty: Hard
Learning Outcome: 9.6 List three potential adverse effects associated with muscle relaxants.

9-15

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