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Psychiatry Osmosis HY Pathology Notes ATF - ATF
Psychiatry Osmosis HY Pathology Notes ATF - ATF
High-Yield
Notes
by
AfraTafreeh.com
PATHOLOGY
Table of Contents
Anxiety Disorders 1
Agoraphobia 2
Generalized Anxiety Disorder 3
Panic Disorder 4
Phobias 5
Separation Anxiety Disorder 6
Social Anxiety Disorder 6
Elimination Disorder 17
Encopresis 17
Enuresis 18
Factitious Disorder 19
Manchausen Syndrome 19
Neurodevelopmental Disorders 23
Attention Deficit Hyperactivity Disorder ADHD 23
Autism Spectrum Disorder 24
Disruptive, Impulse Control and Conduct Disorders 25
Learning Disability 27
Tourette Syndrome 28
Obsessive-Compulsive Disorders 29
Body Dysmorphic Disorder 30
Body Focused Repetitive Disorders 30
Obsessive-Compulsive Disorder 31
Sexual Dysfunction 51
Female Sexual Interest/ Arousal Disorder 52
Genito-Pelvic Pain and/or Penetration Disorder 52
Male Hypoactive Sexual Desire Disorder 53
Orgasmic Dysfuntion 54
CAUSES ( T_R_E~_~_M_EN_T
__ )
• May be genetic, environmental
• Often associated with other mental MEDICATIONS
disorders (mood, substance-related) • Selective serotonin reuptake inhibitors
(SSRls), other antidepressants,
benzodiazepines
( SIGNS & SYMPTOMS )
PSYCHOTHERAPY
• Persistent fear/distress • E.g. cognitive behavioral therapy
• Nausea, difficulty sleeping, headache O Identify, explain thoughts/feelings,
change flawed ones
O Better long-term prognosis; no side
effects. no dependency
1
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AGORAPHOBIA
osmsJl/ e1g0Te1pho\>ie1
(__ s,_G_NS_&_SY_M_PT_O_M_s )
(..____ T_R_E~_iT_M_EN_T
)
• Fast heartbeat, dizziness, trembling
• Thinking about/avoidance of public places
MEDICATIONS
causes distress • SSRls, benzodiazepines
PSYCHOTHERAPY
• E.g. cognitive behavioral therapy,
systematic desensitization
PANIC DISORDER [
end.uT'e o.Ho.cks]
a.lone
AVOIDANCE AVOID PLACES
'>I J,
~ -lemporar~ relief AGORAPHOBIA
~ makes d.ail~ life hard.
* ANTICIPATORY ANXIETY *
Figure 90.1 Illustration showing how other disorders can lead to agoraphobia. If someone with
panic disorder has panic attacks outside frequently, they may develop agoraphobia and avoid
going outdoors altogether.
2
GENERALIZED ANXIETY
DISORDER
osms.i"l/ ge neTo.li2ed-o.nxie-l14-disoTdeT
PSYCHOTHERAPY
• E.g. cognitive behavioral therapy
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(.o.,.flicTU,'1'
Fu~cno 1-1 !.o'-•IIL'-'I'
P~n.1t1t,'TU
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3
PANIC DISORDER
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~. CAA\!~ BEl.l~FS
Ii. E,tp~u~E:
t ,-4i\<.0~0V\..
Figure 90.3 Illustration showing possible causes for panic disorder, and avenues to treatment.
4
PHOBIAS
osms.tl/ pho\>io.
(__ SI_G_NS_&_S_Y_M_PT_O_M_s_)
• Response to phobic stimulus: elevated
heartbeat, dizziness, trembling
• Excessive thinking about/avoidance of
phobic stimulus causes distress
Y:,ro11',,0•'1.a.
~i'llac.ip"'o'eiia.
\)\lo'i1~S
.~:....
• 111~11-ltnII'·~\..
• t,1<l<a\.u~
• ,.,.•••EM•'•,..
Figure 90.4 Illustration of different specific phobias making someone feel powerless.
5
SEPARATION ANXIETY DISORDER
osms.i"l/ sepe1Te1-l:ion-e1nxie-l:14-disoTdeT
( T_R_E~_~_M_EN_T__ )
(__ SI_G_NS_&_SY_M_PT_O_M_s_)
MEDICATIONS
• Distress caused by thought of experiencing • SSRls, benzodiazepines
separation
• Nightmares, headaches, nausea PSYCHOTHERAPY
• E.g. cognitive behavioral therapy
6
( T_R_E~_~_M_EN_T
)
MEDICATIONS
• SSRls, antidepressants, benzodiazepines
PSYCHOTHERAPY
• E.g. cognitive behavioral therapy
CRUSE.. - Ul'JC.LE:AR
D5M-5
_. lndl'11duGll> fto.r athn..7 vi Gt wo.'J -\vull mLjnt mo.~ -thcrv1 9tl JU06E,O,
'f l"~trfett> wl.{n NORMAL IZ.OUTll'JE: S. R~LA1lOl"JSHlP.S.
Figure 90.5 Illustration of the possible causes of social anxiety disorder, which are still unclear,
as well as the DSM-5's criteria for a diagnosis of the condition.
7
NOTES
CAUSES
• Past trauma/stress may cause/worsen
( T_R_E_AT_M_E_N_T
__ )
condition
• See individual disorders
COMPLICATIONS
• Personality changes, depression
AMNESIA
osms.i-l:/ C1mnesiC1
CAUSES
TYPES • Head trauma, infection, neurodegenerative
Anterograde amnesia diseases (e.g. dementia/Alzheimer's),
brain tumours. thiamine deficiency
• Inability to form new memories
(causing Wernicke-Korsakoff syndrome),
• Associated with encoding and
benzodiazepines, electroconvulsive therapy
consolidation phases of memory
• Usually involves damage to prefrontal
cortex/hippocampus COMPLICATIONS
• Range of potential complications (e.g.
Retrograde amnesia confusion, loss of identity)
• Inability to recall old memories (may result
in creation of false memories)
8
(
(..___s,_G_Ns_&_s_v_M_PT_O_M_s
) T_R_E~_~_M_EN_T
)
• Acute memory loss, affects memories PSYCHOTHERAPY
created before/after an event (or onset of • Occupational and cognitive therapies to
illness) enhance memory
LAB RESULTS
• Nutritional deficiencies/infections
DELIRIUM
osmsJl/deliTium
9
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OTHER INTERVENTIONS
(..__ __ T_R_E~_~_M_EN_T
)
Preventative
MEDICATIONS • Make high-risk targets feel oriented,
comfortable (reducing excess noise/
Severe symptoms
stimulation; make sure glasses, hearing aids
• Haloperidol/second generation are used if needed; encourage daily routine)
antipsychotics
• Avoid opiates. other causative medications;
avoid restraints
DISSOCIATIVE DISORDERS
osmsJl/dissoeio.-1:ive-disoTdeTs
• Worsens under stress
( PATHOLOGY & CAUSES )
High severity: dissociativeidentity disorder
• Characterized by disruptions or • Feeling of having multiple identities which
breakdowns of memory, awareness, act/think/perceive differently, thus impairing
identity, or perception. ability to recall everyday/important
information about oneself
TYPES • Two categories of dissociative identity
• Three types on scale of severity disorder
= Covert: individual aware of identity
Low severity: depersonalization/derealiza- shifts, struggles to manage them
tion disorder = Overt: individual completely assumes
• Depersonalization: feeling detached from different identities while unaware
own body/mind (e.g. feeling one's body is a • Can involve dissociative fugue (individual
robot/ feeling of watching self) becomes confused about identity, starts
• Derealization: feeling of world not being sudden travel/ wandering)
fully real (e.g. feeling outside world not real/
lacks lucidity)
CAUSES
Middle severity: dissociativeamnesia • Thought to be primarily caused by
• Inability to recall significant information psychological trauma; associated with
about oneself (e.g. location of childhood sexual abuse. post-traumatic stress
home, what mother looked like) disorder, depression, substance abuse.
borderline personality, somatoform
• Four categories of amnesia
conditions
O Localized: trouble recalling traumatic
• More common in biologically-female
event (and surrounding period)
indiviudals
O Generalized: trouble recalling significant
portion of one's past
O Systematized: trouble recalling
category of information
specific ( SIGNS & SYMPTOMS )
°Continuous: trouble recalling events Depersonalization
/derealization disorder
after they occur • Explicit thoughts/behaviors related to
• Can involve dissociative fugue (individual depersonalization/derealization
becomes confused about identity, starts
• Emotional/physical numbness; weak sense
sudden travel/ wandering) of self
10
• Deadpan speech
• Altered sense of time
( T_R_E~_~_M_EN_T )
• Brain fog/lightheadedness MEDICATIONS
• Prone to rumination, anxiety • Antidepressants (like selective serotonin
• Severe symptoms: difficulty recognizing reuptake inhibitors)
familiar places, people, objects • Mood stabilizers
Dissociativeamnesia & Dissociativeidenti- • Neuroleptics
ty disorder
• Inability to recall significant information PSYCHOTHERAPY
about oneself • E.g., psychodynamic, cognitive, cognitive
• Altered consciousness (e.g. behavioral, supportive
depersonalization, derealization)
• Depression, suicidal ideation
OTHER INTERVENTIONS
• Memory aids: alarms, reminders, media
( D_IA_GN_o_s,_s__ ) (e.g. photos/videos/recordings)
• Occupational therapy
Depersonalization/derealizationdisorder
• Presence of depersonalization/derealization
• Symptoms affect day-to-day functioning
• Not caused by other condition/substance
Dissociativeamnesia
• Inability to recall significant information
about oneself, beyond everyday forgetting
• Symptoms affect day-to-day functioning
• Not caused by other condition/substance
Dissociativeidentity disorder
• Feeling of having multiple identities which
act/think/ perceive differently
• Inability to recall significant information
about oneself, beyond everyday forgetting
• Symptoms affect day-to-day functioning
• Not described by cultural/religious practices,
nor by play (e.g. imaginary friends)
• Not caused by other condition/substance
11
NOTES
COMPLICATIONS
• Self-harm/suicide
PSYCHOTHERAPY
• See individual disorders
• Social consequences (e.g. losing friends)
OTHER INTERVENTIONS
(__ s,_G_NS_&_SY_M_PT_O_M_s_) • Lifestyle changes
, Improved diet, more exercise, more
• Manic episodes featuring a mood sunlight
disturbance, increased energy/activity,
and z three of following for z one week,
affecting day-to-day functioning
• Hypomanic ("less than manic") episodes
featuring a mood disturbance, increased
energy/activity, and ;;:: three of the above
during a period > four days, not affecting
day-to-day functioning
• Major depressive episodes featuring ;;:: five
of following in a two week period
• Other mood changes, including more mild
depression; see individual disorders
12
BIPOLAR I DISORDER
osms.tl/\,ipolo.,--1
i
Characteristics of manic
episode
Distractibility MEDICATIONS
Indiscretion: excessive • Atypical antipsychotics (e.g. olanzapine).
involvement in pleasurable in combination with mood stabilizers (esp.
activities lithium)
Grandiosity
Flight of ideas PSYCHOTHERAPY
Activity increase • E.g. cognitive behavioral therapy,
Sleep deficit/decreased need interpersonal
for sleep
Talkativeness/pressured OTHER INTERVENTIONS
speech
• Electroconvulsive therapy (ECT)
13
BIPOLAR 11 DISORDER
osms.i-l/\>ipolo.T-11
14
\ MNEMONIC: SIG ED CAPS
Diagnostic criteria for Major
( T_R_E~_~_M_EN_T
)
depressive disorder
MEDICATIONS
Sleep: increased or decreased
• Antidepressants (SSRls, SNRls, NDRls)
Interest: decreased
Guilt/worthlessness
Energy: decreased or fatigued PSYCHOTHERAPY
• E.g., cognitive behavioral therapy,
Depressed mood most of the
interpersonal
day
Concentration/difficulty making
decisions OTHER INTERVENTIONS
Appetite and/or weight • Improved diet, more exercise, more sunlight
increase or decrease
Psychomotor activity:
increased or decreased
Suicidal ideation/ thoughts of
death
PREMENSTRUAL DYSPHORIC
DISORDER
osmsJl/ pTeme ns-lTue1l-cJ.14sphoTie-disoTdeT
= Inabilityto sleep/oversleeping
( PATHOLOGY & CAUSES ) • Feelings of being overwhelmed
= Mild physical symptoms (e.g.
• Depressive disorder characterized by mood
tenderness/swelling)
changes during menstrual cycle
CAUSES ( D_IA_GN_O_s,_s __ )
• Unknown; possible sensitivity to hormonal
changes • Mood changes s one week before menses,
as evidenced by presence of z five of
symptoms (;;:: one from each category),
(__ s,_G_NS_&_S_Y_M_PT_O_M_s_) resolving within one week post-menses
• Must occur during majority of menstrual
• Emotional cycles over past year
O Affective !ability
• Symptoms affect day-to-day life
O Irritability/anger • Not caused by other condition/substance
O Anxiety/angst
• Other symptoms
O Diminished interest/pleasure
O Decreased concentration
° Fatigue
o Weight loss/gain
15
PSYCHOTHERAPY
(..____ T_R_E~_~_M_EN_T
) • E.g. cognitive behavioral therapy,
interpersonal
MEDICATIONS
• SSRls, oral contraceptives
OTHER INTERVENTIONS
• Lifestyle changes: improved diet, more
exercise, more sunlight
SEASONAL AFFECTIVEDISORDER
osmsJl/seo.sono.1-o.ffee-live-disoTdeT
CAUSES
• Exact cause unknown; runs in families,
C T_R_E~_~_M_EN_T__ )
especially between close relatives;
linked to neurotransmitter regulation
MEDICATIONS
(norepinephrine, serotonin, dopamine); high • Antidepressants (SSRls, SNRls, NDRls)
comorbidity with other mental disorders
PSYCHOTHERAPY
C__s,_G_Ns_&_s_v_M_PT_O_M_s_) • E.g. cognitive
interpersonal
behavioral therapy,
16
NOTES
(__ SI_G_NS_&_S_Y_M_PT_O_M_s
)
PSYCHOTHERAPY
• Repeated voluntary/involuntary passage of • E.g. cognitive behavioral therapy
feces/urine into inappropriate places
ENCOPRESIS
osms.i"l/ e nee Tes is
PSYCHOTHERAPY
• Behavioral therapy
O Encourage toilet usage, normalize bowel
movements
ENURESIS
osms.i"l/enuTesis
PSYCHOTHERAPY
(__ SI_G_NS_&_SY_M_PT_O_M_s
)
• Behavioral therapy (e.g. bedtime alarm
• Repeated voluntary/involuntary passage of therapy), bladder program
urine into inappropriate places
18
NOTES
MUNCHAUSENSYNDROME
osms.i"l/muneho.usen-s14ndTome
CAUSES
• High comorbidity with mood/personality (..____ T_R_EA_:T_M_EN_T__ )
disorders
PSYCHOTHERAPY
• Various psychotherapy methods
(_~SI_G_NS_&~SY_M_P_TO_M_S~)
Munchausen syndrome by proxy
Munchausen syndrome • Family therapy helpful
• Feigned symptoms • Separate perpetrator, victim
Munchausen syndrome by proxy • Treat victim for induced illness/injury/
emotional trauma
• Purposefully inducing symptoms in another
• High level of perceived interest in victim/
victim's condition (if applicable)
Both types
• Limited but highly-relevant medical
knowledge
19
NOTES afratafreeh.com exclusive
OTHER INTERVENTIONS
• Careful weight gain
20
ANOREXIA NERVOSA
osmsJl/e1noTexie1-neTvose1
hair falls out, menstruation stops, difficulty
( PATHOLOGY & CAUSES ) breathing, slow heartbeat, hypotension,
congestive heart failure, edema (especially
• Eating disorder characterized by restrictive in feet), bone marrow shuts down (---->
food intake (leading to significantly low dampened immune response, low energy
body weight), fear of weight gain, distorted levels, easier bleeding/bruising)
view of body • If purging by vomiting: enamel erosion,
• Often begins in teens/early adulthood parotid gland swelling, bad breath, bruised/
calloused knuckles (Russell's sign), stomach
TYPES tearing, fast heartbeat, depletion of
electrolytes
Atypical anorexia nervosa
• Label for individuals with anorexia
symptoms without significantly low body (..____ D_IA_GN_O_SI_S
__ )
weight
• Restrictive food intake (leading to
Restricting anorexia nervosa significantly low body weight)
• Individual loses weight only by via highly • If body weight cannot be described as
restricted food intake/excessive exercise significantly low, diagnosis = atypical
anorexia nervosa
Binge-eating/purging anorexia nervosa
• Fear of weight gain
• Individual loses weight by purging (e.g.
• Distorted view of body
vomiting, use of laxatives/diuretics/enemas)
• Restricting type: individual has not
repeatedly binge-eaten or purged over s
CAUSES three months (instead, attempts to lose
• Genetic (e.g. abnormalities in hunger weight by restricting food intake/exercising
signals). environmental (e.g. peer pressure/ excessively)
forces of popular culture) • Binge-eating/purging anorexia nervosa:
• High comorbidity with obsessive- repeated binge-eating/purging over s three
compulsive disorder, depression, anxiety months
Specify severity
COMPLICATIONS • Mild: BMI > 17
• Refeeding syndrome. difficulty breathing,
• Moderate: BMI 16-17
heart failure, brain damage, suicidal
• Severe: BMI 15-16
ideation. death
• Extreme: BMI < 15
(__ SI_G_NS_&_S_Y_M_PT_O_M_s
)
(..____ T_R_E~_~_M_EN_T
__ )
• Fear of weight gain----> restrictive food
behaviors, purging, excessive exercise. PSYCHOTHERAPY
weight checks. food rituals • E.g. cognitive behavioral therapy
• Restrictive food intake ----> electrolyte
abnormalities. vitamin deficiencies, muscle OTHER INTERVENTIONS
loss. low creatinine levels. fatigue----> brain • Careful weight gain
damage, weakened bones. dry/scaly skin,
21
BULIMIA NERVOSA
osms.i"l/\,u limio.-neY-voso.
• Compensatory behaviors to prevent weight
( PATHOLOGY & CAUSES ) gain, concurrent with binge-eating
• Distorted view of body, belief that body
• Eating disorder characterized by repeated weight/appearance crucial for self-worth
binge-eating, compensatory behaviors
to prevent weight gain, belief that body Specify severity
weight/appearance crucial for self-worth • Mild: 1-3 compensatory behaviors/week
• Compensatory behaviors/"purges": • Moderate: 4-7 compensatory behaviors/
vomiting, use of laxatives/diuretics/enemas week
• Attempts to conceal behaviors • Severe: 8-13 compensatory behaviors/
• Often begins in teens/early adulthood week
• Extreme: > 14 compensatory behaviors/
CAUSES week
• Genetic (e.g. abnormalities in hunger
signals), environmental (e.g. peer pressure/
forces of popular culture) (.._____ T_R_E~_~_M_EN_T
)
• High comorbidity with obsessive-
compulsive disorder, depression, anxiety
MEDICATIONS
• Antidepressants (e.g. selective serotonin
reuptake inhibitors)
COMPLICATIONS
• Refeeding syndrome, diabetes mellitus, fast
heartbeat, suicidal ideation, death
PSYCHOTHERAPY
• E.g. cognitive behavioral therapy
(.___s,_G_NS_&_S_Y_M_PT_O_M_s_)
OTHER INTERVENTIONS
• Careful weight gain
• Binge-eating, compensatory behaviors
(usually purposeful vomiting)
• Endocrine changes----. menstruation stops/
never starts, increased risk of diabetes
mellitus
• If purging by vomiting: enamel erosion,
parotid gland swelling, bad breath, bruised/
calloused knuckles (Russell's sign), stomach
tearing, fast heartbeat, depletion of
electrolytes
(.._____ D_IA_GN_O_s,_s)
• Must occur exclusive of anorexia nervosa
• Repeated binge-eating over s three Figure 95.1 Erosion of the enamel of the
months mandibular teeth of an individual with bulimia
• Binge-eating classification requires sense nervosa.
of loss of control
22
NOTES
( T_R_E~_~_M_EN_T__ )
CAUSES
• Genetic, environmental • Not curative
• See individual disorders
COMPLICATIONS
• Reduced success in various areas of life
(esp. social, academic)
ATTENTION DEFICIT
HYPERACTIVITY DISORDER (ADHD)
osms.ll/ ADMD
CAUSES
( PATHOLOGY & CAUSES ) • Genetic, environmental
• Associated with neurotransmitter activity
• Developmental disorder characterized by
(low amounts of dopamine/norepinephrine)
inattentiveness/hyperactivity/impulsiveness,
lasting for> six months
COMPLIC ATIONS
TYPES • Reduced success in various areas of life
(esp. social, academic)
• Inattentive. hyperactive/impulsive, or both
23
( SIGNS & SYMPTOMS ) , Struggles to stay seated
, Restless
, Struggles to keep quiet
• Inattentiveness (careless mistakes, not
listening, easily distracted) , Likes to keep moving
• Hyperactivity/impulsiveness (restlessness) , Talks before others have finished
• Developmental delay (e.g. in linguistid , Doesn't like waiting
social/ motor skills) , Interrupts/bothers others
• Symptoms for either category must
, Persist > six months
(..____ D_IA_GN_O_SI_S
) , Present< 12 years old
, Present in multiple settings
• For inattentive dtaqnosisz six of following
(;;:: five if age > 16) , Affect day-to-day functioning
O Makes careless mistakes/overlooks , Not caused by other condition
details
O Struggles to stay focused
O Doesn't appear to listen
(..____ T_R_EA_~_M_EN_T )
O Doesn't follow instructions MEDICATIONS
O Has poor organizational skills • Stimulants to slowly release
O Avoids mentally-engaging tasks neurotransmitter (e.g. amphetamines =
O Often loses things Adderall/ methylphenidate = Ritalin)
O Is easily distracted
O Is forgetful PSYCHOTHERAPY
• For a hyperactive/impulsive diaqnosis.a six • Behavioral therapy focused on decreasing
of following (;;:: five if age > 16) distractions/improving time management,
O Often fidgets organizational skills
AUTISM SPECTRUM
DISORDER (ASD)
osms.i"l/ cu-lism
CAUSES
( PATHOLOGY & CAUSES ) • Genetic, environmental
24
• Restricted/repetitive behaviors, interests, or
(__ SI_G_NS_&_SY_M_PT_O_M_s_)
activities, with 2:: two of following
O Repetition of particular movements/
• Difficulties with social interaction,
phrases
communication (doesn't understand others'
O Specific routines/rituals, resistant to
emotions/respond to them, struggles to
change
make friends)
O Restricted interests (e.g. highly specific
• Restricted/repetitive nature regarding
knowledge in a subject)
particular behaviors/interests/activities
O Highly sensitive to/interested in
surroundings
( D_IA_GN_O_s,_s
__ ) • Symptoms must have been present in
development, and affect day-to-day
• Struggles with social interaction/ functioning
communication • Not caused by other condition
O Poor emotional reciprocity (doesn't
respond to/communicate emotions,
thoughts) ( T_R_EA_:T_M_EN_T__ )
O Poor non-verbal communication
(especially poor understanding thereof) PSYCHOTHERAPY
O Impaired joint attention (doesn't share • Educational programs, behavioral therapy
interests with others) tailored to individual
O Difficulty in developing/maintaining
relationships
25
(__ SI_G_NS_&_SY_M_PT_O_M_s
) C..____ T_R_EA_~_M_EN_T
)
• Persistent, aggressive or harmful behaviors PSYCHOTHERAPHY
O May involve aggression or harm towards • Focused on therapy, not medications
other individuals or animals • Cognitive behavioral therapy, social skills
O May involve damage to or stealing training, anger management, parent
physical property management training
(..____ D_IA_GN_o_s,_s)
• Multiple impulsive behaviors observed over
an extended period of time
Present 12 months
(continuous) in individuals
Willful aggression
< 18 years old: distresses
daily life
26
LEARNING DISABILITY
osmsJl:/leo.Tning-diso.\>ili-l:14
27
TOURETTESYNDROME
osmsJl/-louTe-He-s14nd Tome
COMPLICATIONS
• Often comorbid with anxiety, depression
(__ SI_G_NS_&_SY_M_PT_O_M_s_)
• Simple/complex tics of either/both types
28
NOTES
CAUSES PSYCHOTHERAPY
• Genetic, often associated with psychiatric • E.g. cognitive behavioral therapy
comorbidities
• Can lead to depressive/substance use
disorders
(__ s,_G_NS_&_S_Y_M_PT_O_M_s_)
• Obsessions, compulsions causing distress
29
BODY DYSMORPHIC DISORDER
osms.i"l/BDD
( PATHOLOGY & CAUSES ) (.._____ D_IA_GN_O_s,_s)
• Characterized by an obsessive belief that • Not caused by other condition/substance
one's appearance is flawed
• Can cause compulsive behaviors (e.g.
excessive grooming) (.._____ T_R_E~_~_M_EN_T
)
• No consensus on optimal treatment
CAUSES
• Genetic, environmental; linked to issues
with serotonin neurotransmitters MEDICATIONS
• SSRls and other antidepressants
Trichotillomania
• Characterized by compulsive hair-pulling
( D_IA_GN_O_s,_s
__ )
• Not explained by any other condition/
CAUSES substance
• High comorbidity with other mood
disorders; stress-related
• Trichotillomania: genetic
30
( T_R_E~_~_M_EN_T
)
• No consensus on optimal treatment
MEDICATIONS
• SSRls and other antidepressants
PSYCHOTHERAPY
• Cognitive behavioral therapy
OTHER INTERVENTIONS
• Physical prevention (e.g. covering exposed Figure 97.1 An individual with excoriation
skin or hair) syndrome and numerous, small skin sores
caused by constant skin scratching and
picking.
OBSESSIVE-COMPULSIVE
DISORDER
osmsJl/OC,D
31
NOTES
Borderline
Antisocial
( D_IA_GN_o_s,_s __ ) CLUSTER 8 Histrionic
Narcissistic
U.U~TE~ A
PAJZ"~'t> S,~\~O\t)
PH-SotJAl..11'( t)1SOII-Pll(
SC.lo\\~c:>1''\'PA\.
\'<:'1-'>oi,i p,1..nt 'i)1So1<\lli
PE~SOtJALIT'( 01SollOEfl
ti \I
f\(C.U5A1"0'2'( ''Aloof"
Figure 98.1 Illustration depicting different types of cluster A personality disorders.
32
PARANOID PERSONALITY
DISORDER
osmsJl/po.To.noid-peTsono.li-l:14-disoTdeT
Figure 98.2 Illustration depicting thoughts and symptoms of paranoid personality disorder.
33
SCHIZOID PERSONALITY
DISORDER
osmsJl/ schizoid- eTsono.li-l14-disordeT
PH'tSIC.Al (ONTA<.T
LESS PLcASVf!ABl-E °"-.
e,_j, SfXVA L AC.TIVITi
e..,j, ~oLOU.J<. HAt'l>S
'-- _)
L k,s l1r.e..1::i to
See\£ ou.t
)
... \SO\.I\TIOtJ
\)\':)T\ ucr yoM
f.t."OTIONAL 6W~1'1~'1
L l)otJ't Sttow Pos,,-1vf ~ 1.JtC>11T1\/£. PA~t:\WOIA &. ~~\~~v
Figure 98.3 Illustration depicting thoughts and symptoms of schizoid personality disorder.
34
SCHIZOTYPAL PERSONALITY
DISORDER
osmsJl/ sehi20-l:14po.l-peTsono.li-l:14-disoTdeT
CAUSES
• May be genetic, environmental ( T_R_E~_~_M_EN_T
)
• Linked to schizophrenia
PSYCHOTHERAPY
• Aimed at improving social understanding;
(__ SI_G_NS_&_S_Y_M_PT_O_M_s_) can be challenging due to trust issues
• Ideas of reference
• Altered perception
• Unusual thinking/talking (vague, not
incoherent)
• Paranoia/anxiety
Figure 98.4 Illustration depicting thoughts and symptoms of schizotypal personality disorder.
35
NOTES
Figure 99.1 Illustration depicting the four cluster B personality disorders: antisocial personality
disorder, borderline personality disorder. histrionic personality disorder. and narcissistic
personality disorder.
36
ANTISOCIAL PERSONALITY
DISORDER
osms.i"l/ o.n-l.isoeio.l-persono.li-l.14-disorder
( T_R_EA_:l"_M_EN_T__ )
PSYCHOTHERAPY
• E.g. self help groups
t)1~U~A~D fo' 1
'"'"" """"'t
!"\Of.Al.. VI\W~S
~ C.HAit.A1tJ~
L used. to MAIJIPvtAlE
LITTlE EM\>AT~'( ......--' t( JO' l'f\?'i,OIJI\\. C.1111.l
P()Of- 'IM~
CP~l10\..
J-
.)
......_ NO (ZEVIO~t/ C,ul~T
l \)o~l 0<«9t Yc~Vlll'o<li~
5,,, "l\\?M
l,JlllllJC. "Tl>
Hun onu:ll.\ ~bitss,vt "'=>0L1ovl\-ttt"
lf tr --- ..~ i<U,..LA\Alf\JL--+ 0'
Figure 99.2 Illustration depicting thoughts and symptoms of antisocial personality disorder.
37
BORDERLINE PERSONALITY
DISORDER
osms.i"l/\>oTdeTline- eTsono.li"l14-disoTdeT
t)tFEOJS( r-\lOAl<ISM
S9llTTHJ~ --- I~rt:JJS.f
1 So-"~ Wot-.Jt>E~FvL
lMl'O~IIN11'111~<,S~-~ 'joe)
~ELA110..iS\-\1PS
~~
UOOO or 6AO
c. TEJ.~lflEO oj A6A .... 01)W~EtJT'
L ~to'l'Y\e. o~,w.,._,·v..
11.
j,oM \eov1V1~
Figure 99.3 Illustration depicting thoughts and symptoms of borderline personality disorder.
38
HISTRIONIC PERSONALITY
DISORDER
osms.i-l/his-lrionie-persono.li-l'4-disorder
O Vague speech
• May be genetic, environmental
O Exaggerated manner
O Easily affected by others/situations
(__ SI_G_NS_&_S_Y_M_PT_O_M_s_)
Mistakes relationships O as more intimate
• Not explained by other condition
• Exaggerated thoughts, feelings (e.g.
tantrums)
• Superficial relationships ( T_R_E~_~_M_EN_T
__ )
• Excessively seductive behavior
• Attention-seeking behavior PSYCHOTHERAPY
• Psychoanalytic therapy
ATT€Ul'IO~-SE£tt1~4
£'1.(.ESSIVE "'
f MOTIO>JAUTV --......_
l
Figure 99.4 Illustration depicting thoughts and symptoms of histrionic personality disorder.
39
afratafreeh.com exclusive
NARCISSISTIC PERSONALITY
DISORDER
osms.i"l/ ne1Teissis-lie-persone1li-l14-disorder
u~~WDIOSE
5Hf-1MA6£ D
o
~ f ~llf SHF-(St££M
LvuLtJEl!ABLc To
C~\TlllS,M
LL11~£~ our
W'M.V\ .fu.\1V,&
Sl.1<.~'tl-1)
Figure 99.5 Illustration depicting thoughts and symptoms of narcissistic personality disorder.
40
NOTES
PSYCHOTHERAPY
(__ s,_G_NS_&_S_Y_M_PT_O_M_s_) • E.g. behavioral therapy, group therapy,
assertiveness training
• Unusual behavior
• Poor relationships
Figure 100.1 Illustration depicting the three cluster C personality disorders: avoidant personality
disorder, obsessive-compulsive personality disorder, and dependent personality disorder.
41
AVOIDANT PERSONALITY
DISORDER
osms.i"l/ o.voido.n-l-peTsono.ltt:14-disoTdeT
PSYCHOTHERAPY
• E.g. group therapy, assertiveness training
SHV
1
WS\tJ'fS C..LOS(
itt.ri.110N~\11PS.Bvr ...
il~\l) ..::::::
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: ~:~;~nlt
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~ Xle.lO'!Yle~ ~~ u,ihldro.Vh\..
42
OBSESSIVE-COMPULSIVE
PERSONALITY DISORDER
osms.i-l/ o\>essive-complusive
PSYCHOTHERAPY
• Cognitive behavioral therapy, group therapy
• ~tJ1\t"f'1 'D1!>0iVf.~ •
\.... ?c,\>(-'atiOYI Dy E.uo -5'fWTOtJI(.
i'1tl.lo.1is~k o.c..-t>~f\'> l..\l\o.?~'a o,:,"1tli\. ~OUJ -ti/\~ O.~
£C..O-D'lSTOtJ\C.. , ._, u:,wa..
l>JISv,e!:. -h\e~
Sitl p
\... ~011-\:. IIJO.(I\;. "tO CVIO.'l\~e
Figure 100.3 Illustration depicting differences between obsessive compulsive disorder and
obsessive compulsive personality disorder.
43
DEPENDENT PERSONALITY
DISORDER
osms.i"l/ depe nde n-l-pel9sono.li-l14-disol9del9
PSYCHOTHERAPY
• E.g. insight oriented, behavioral, family,
group, assertiveness training
LACJ:S
1~1ttJ5.E. Jeo.r 1· .. / SEt.f~ (ONFll>UJc.£
~ SEPAAATlOW
• ieJtc:noN
44
NOTES
Mood-related symptoms
(__ SI_G_NS_&_S_Y_M_PT_O_M_s_)
• Sometimes
PSYCHOTHERAPY
• E.g. individual/group therapy, rehabilitation
45
~C.\i\l.O 9\.\\2.fNI f4 \o~ ~ Sj'l\l\ftt""\
DELUSIONAL DISORDER
osms.i"l/ cJ.elusione1l-cJ.isorcJ.er
Non-bizarre delusions
( PATHOLOGY & CAUSES ) • Persecutory
, Others conspiring against/following
• Mental disorder characterized by persistent
oneself
delusions
• Jealous
• Delusions may be bizarre (impossible)/non-
bizarre (possible, but still wrong) , One's partner unfaithful
46
( D_IA_GN_O_s,_s __ ) ( T_R_E~_~_M_EN_T__ )
• ~ one delusion, over ~ one month MEDICATIONS
period, without meeting other criteria for • Antipsychotics, antidepressants
schizophrenia
O Hallucinations may occur in some cases
PSYCHOTHERAPY
of delusional disorder
• E.g. individual/group therapy, rehabilitation
• Affects day-to-day functioning
• Not caused by other condition/substance
SCHIZOAFFECTIVE DISORDER
osms.i"l/ sehizoo.ff ee-l.ive-disoTdeT
MEDICATIONS
(__ s,_G_NS_&_S_Y_M_PT_O_M_s_) • Antipsychotics, antidepressants
• Positive symptoms
O Delusions, hallucinations, disorganized PSYCHOTHERAPY
speech, disorganized behavior • Dialectical behavior therapy, mentalization-
• Negative symptoms based therapy, transference-focused
° Flat affect, alogia, avolition therapy
• Mood-related symptoms
O Depression, suicidal ideation
O Manic episodes (e.g. euphoria,
grandiosity, hyperactivity)
( D_IA_GN_o_s,_s __ )
• ~ two of following (+ at least one of first
three) + a mood disorder
o Delusions
O Hallucinations
O Disorganized speech
O Disorganized or catatonic behavior
O Negative symptoms
• Delusions/hallucinations last z two weeks
beyond mood episode
• Not caused by other condition/substance
47
SCHIZOPHRENIA
osmsJl/ sehizophTenio.
CAUSES
• Success of treatment with dopamine ( T_R_E~_~_M_EN_T
__ )
antagonists suggests link to increased
dopamine levels MEDICATIONS
• Genetic; more common in biological males • Antipsychotics
(__ s,_G_NS_&_SY_M_PT_O_M_s_)
• Positive symptoms
O Delusions, hallucinations, disorganized
speech, disorganized behavior
• Negative symptoms
° Flat affect, alogia, avolition
• Cognitive symptoms
O Difficulties with memory, learning,
understanding
48
Sc.H\c.0 9\\(lfNI"
P~ASlS
0>~oOlOIW\A~ - • (Ac.TIU€ j
• wi#tdrelk.111\ • SEvE.IU: S'1fWl~To~S
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• . 1
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r ,
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_ tOl\cHofl•L .._,.,,ca"4°""
"
\.__ \ ~SIOUA\. /
SCHIZOPHRENIFORM DISORDER
osms.i-1:/sehizophTenifoTm-cJ.isoTdeT
PSYCHOTHERAPY
• E.g. individual/group therapy, rehabilitation
49
Avoid social interaction, lack friends, flat affect, lack of sexual interest. "Lone wolf'';
Not caused by paranoia or social anxiety
(Overlaps with Negative symptoms of Schizophrenia)
"Fixed false belief'' that lasts > 1 month without other schizophrenia criteria
50
NOTES
GENERALLY.WHAT IS IT?
( PATHOLOGY & CAUSES ) (__ s,_G_NS_&_SY_M_P_TO_M_s_)
• Sexual function disturbances, often causing • Sexual dysfunction
distress , E.g. I/absent orgasmic function, altered
• May be lifelong/acquired, mild/moderate/ libido
severe, generalized/situational • Anxiety, distress
Associated factors
• Medical diagnoses ( D_IA_GN_O_s,_s __ )
O E.g. diabetes mellitus, thyroid
dysfunction OTHER DIAGNOSTICS
• Relationship issues • Based on specific sexual-disturbance
O E.g. impaired interpersonal presence
communication, intimate partner ° Causing individual distress
violence O Not better explained/accounted for by
• Cultural/religious factors another medical condition, non-sexual
O E.g. negative attitudes/prohibitions psychological disorder, interpersonal
regarding sexual activity stress, substance
• Individual vulnerabilities
OE.g. history of abuse, psychiatric
comorbidity-anxiety, depression, ( T_R_E~_~_M_EN_T__ )
intrapsychic conflict, psychosocial
st res so rs
MEDICATIONS
• See individual disorders
• Partner issues
O E.g. mental, physical. sexual health
issues PSYCHOTHERAPY
• See individual disorders
51
FEMALE SEXUAL INTEREST I
AROUSAL DISORDER
osms.i-l/f emC1le-C1TousC1l-disoTdeT
, Sexual/erotic thoughts
( PATHOLOGY & CAUSES ) , Sexual activity initiation; partner
initiation receptivity
• Disorder characterized by either absence
, Pleasure/excitement durinq a 75% of
or! frequency/intensity of sexual/erotic
sexual encounters
activity or thoughts in biological females
, Interest/arousal in sexual/erotic-cue
settings
(__ SI_G_NS_&_SY_M_P_TO_M_s_) , Genital/non-genital sensation during ;;::
75% of sexual encounters
• Self-reported !/absent sexual pleasure,
genital/nongenital sensations, ! vaginal
lubrication - anxiety/distress (..____ T_R_E~_iT_M_EN_T
)
MEDICATIONS
( D_IA_GN_O_s,_s __ ) • Flibanserin, bupropion
52
• Low estrogen levels intercourse/penetration attempts
, Fear/anxiety in anticipation of, during,
after penetration
( SIGNS & SYMPTOMS ) , Pelvic floor muscle tensing during
penetration attempts
• Dyspareunia
O Pain described as superficial/deep;
throbbing, shooting, burning ( TREATMENT )
• Pelvic floor muscle guarding, reflexive
spasms PSYCHOTHERAPY
• Avoidance of intimate sexual activity/ • Cognitive-behavioral and/or psychosexual
recommended gynecological exams therapy
• Resulting anxiety/distress
OTHER INTERVENTIONS
• Pelvic physical therapy
(.____ D_IA_GN_O_s,_s __ ) • Address underlying cause
OTHER DIAGNOSTICS • E.g. ospemifene for dyspareunia
(vulvovaginal atrophy)
• Recurring one/more difficulties persisting
for ~ six months ----. distress, not better
explained by non-sexual factors
O Vaginal penetration during intercourse
O Vulvovaginal/pelvic pain during
53
(..__ __ T_R_E~_~_M_EN_T
)
MEDICATIONS
• Bupropion
PSYCHOTHERAPY
• Cognitive-behavioral/psychosexual therapy
ORGASMIC DYSFUNCTION
osmsJf:/ 0Tge1smie-d14sfunelion
Male
( PATHOLOGY & CAUSES ) • ED: presence of one of following symptoms
experienced during 2: 75% of sexual
• Orgasmic sensation absence, infrequency,
activity; persisting for 2: six months -
! intensity, delay distress; not better explained by nonsexual
Female cause
, Difficulty obtaining erection
• Female orgasmic disorder: difficulty
experiencing normal orgasmic function , Difficulty maintaining erection
, ! erectile rigidity
Male • Abnormal ejaculation
• Erectile dysfunction (ED): persistent , Delayed ejaculation
inability to obtain/maintain erection
, Ejaculation infrequency/absence
• Abnormal ejaculation (premature, delayed)
, Premature ejaculation
(__ SI_G_NS_&_S_Y_M_PT_O_M_s_)
( T_R_E~_~_M_EN_T
)
• Reported impaired orgasmic function
during sexual activity
MEDICATIONS
• Sildenafil
• Low self-esteem, ! sense of sexual self -
depressed affect
PSYCHOTHERAPY
• Cognitive-behavioral/psychosexual therapy
(..____ D_IA_GN_O_SI_S
)
OTHER DIAGNOSTICS
Female
• Presence of one of following symptoms
experienced during 2: 75% of sexual
activity; persisting for 2: six months -
distress: not better explained by nonsexual
cause
O Orgasm delay, infrequency, absence
(specify if orgasm never experienced)
0 ! orgasmic intensity
54
NOTES
CAUSES ( D_IA_GN_O_s,_s __ )
• Stress, substance use, medical conditions
• See individual disorders
COMPLICATIONS
• Affects quantity/quality of sleep, causing
lack of restorative sleep ----> irritability, ( T_R_E~_~_M_EN_T__ )
anxiety, depression
• See individual disorders
BRUXISM
osms.i"l/\>Tuxlsm
( D_IA_G_N_OS_IS)
COMPLICATIONS
• Can cause temporomandibular joint OTHER DIAGNOSTICS
disorder • Persistent grinding/clenching of teeth
• Not caused by other condition
55
(..____ T_R_E~_~_M_EN_T
)
MEDICATIONS
• Avoid stimulants, depressants
OTHER INTERVENTIONS
• Sleep bruxism: mouth guards, occlusal
splints, dental plates, muscle relaxants, oral
surgery
• Awake bruxism: behavior modification
Figure 103.1 Bruxismcauses flattening of the • Minimize chewing
occlusal surfaces as seen here.
INSOMNIA
osms.i"l/insomnio.
NARCOLEPSY
osms.i"l/ ne1Teoleps14
CAUSES
• Damage to orexin-transporting neurons ( T_R_E~_~_M_EN_T
__ )
O By autoimmune process/injury)
MEDICATIONS
• Selective serotonin reuptake inhibitors
RISI( FACTORS (SSRls), stimulants (e.g. modafinil)
• Genetic factors, low levels of histamine,
infections, autoimmune diseases
(__ SI_G_NS_&_S_Y_M_PT_O_M_s_)
• Daytime sleepiness
• Cataplexy (strong emotions cause muscle
weakness)
• Hallucinations
O Hypnagogic: happen when falling
asleep
O Hypnopompic: happen when waking up
• Sleep paralysis
O Regaining consciousness while body's
muscles are paralyzed during sleep
57
NIGHT TERROR
osms.i"l/ nigh-l--leTToT
(......___ T_R_E~_iT_M_EN_T
)
RISI( FACTORS
• Most common in children (3-8 years old) OTHER INTERVENTIONS
• Reduce stress, follow nighttime routine
• Often resolves spontaneously (esp. in
(__ SI_G_NS_&_SY_M_PT_O_M_s_)
children)
• Night terrors
O Begins with sharp scream - individual
sits up - unresponsive - when
awoken, individual confused, has no
memory of episode
NOCTURNAL ENURESIS
osms.i-l/ noe-luTno.1-enuTesis
CAUSES
C D_IA_GN_o_s,_s
__ )
• Poor bladder control (for physiological OTHER DIAGNOSTICS
developmental reasons)/simply exceeding • Repeated, uncontrolled passage of urine
bladder capacity into bed/clothes during the nighttime
• Genetic, environmental • "Clinically significant"
° Comorbid with other mental disorders , Occurs z two times/week for z three
O More common in biological males consecutive months or affects day-to-
58
day functioning
• ;:=: five years old
• Not caused by other condition/substance
( T_R_E~_~_M_EN_T__ )
• Often resolves spontaneously
MEDICATIONS
• Desmopressin - reduces urine production
PSYCHOTHERAPY
• Behavioral therapy
O Esp. bedwetting alarm therapy
O Moisture-detecting alarm wakes
individual up during enuresis
OTHER INTERVENTIONS
• Bladder program
O To build good habits
59
NOTES afratafreeh.com exclusive
60
ALCOHOL USE DISORDER
osmsJl/ e1leohol-use-clisoTcleT
Figure 104.1 Illustration showing alcohol's effects on the hypothalamus, pituitary glands, and
medulla.
CANNABIS DEPENDENCE
osms.i"l/ eo.nno.\>is_de endenee
• Continued cannabis use causes tolerance
( PATHOLOGY & CAUSES ) , Cannabinoid receptors become less
sensitive/neurons have fewer receptors
• Inability to feel "normal" without cannabis (downregulation)
• Cannabis use disorder: maladaptive pattern , Must consume more to feel euphoric
of cannabis use (positive reinforcement)
• Cannabis = depressant/stimulant • Withdrawal
62
COMPLICATIONS O Giving up important activities for
• Anxiety, depression, psychotic disorders cannabis
(e.g. schizophrenia), hyper-inflated O Using cannabis in dangerous situations
lungs (when smoking cannabis), chronic O Using cannabis even if it worsens a
bronchitis, respiratory infections, heart problem
attacks, strokes O Becoming tolerant to cannabis
• Teenagers at higher risk (developing brain O Withdrawal symptoms
more sensitive)
• Mild = 2-3 symptoms, moderate = 4-5
symptoms, severe=::::: six symptoms
( SIGNS & SYMPTOMS )
• Increased cannabis tolerance
( T_R_EA_:T_M_EN_T__ )
• Upon withdrawal PSYCHOTHERAPY
, Cravings, irritability, anxiety, difficulty • Motivational interviewing
sleeping
( D_IA_GN_O_s,_s __ )
OTHER DIAGNOSTICS
• ::::: two of following
, Consuming more cannabis than
intended
, Inability to cut down
, Cannabis use takes up a lot of time
= Cravings to use cannabis
, Cannabis use affects responsibilities
, Using cannabis despite social problems
Co11110AJ ,11
"~----
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I " A.ir1-lo.1fLAMMATol?'c'
"' l i:!1J1'1•>(ll0'1(
14 II M
\.. APP(T,TE. ST1IIULl!Tli16
Figure 104.3 Illustration showing the stimulant effects of tetrahydrocannabinol (THC) versus the
depressant effects of cannabidiol (CBD). CBD's properties mean it can be used medicinally in
some cases.
63
S~VtiE UlN~Ai?>l~
be.Pt~ t:>f.N ,£
( l.AuSALl"f~ ?
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PwtSl(AL. (rftCT~
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..e- TtklrAr1vE1."I'
L l-4E.Ai, ArrllC.KS.
1.. Sr!lol<E.
Figure 104.4 Illustration showing the potential physical and mental effects of severe cannabis
dependence.
COCAINE DEPENDENCE
osmsJl/ eoee1ine-dependenee
(positive reinforcement)
(..____ D_IA_GN_O_SI_S
)
• Withdrawal OTHER DIAGNOSTICS
• ;;,: two of fol lowing
COMPLICATIONS , Consuming more stimulants than
• Hyperthermia, seizures, stroke, brain intended
hemorrhage, heart attack, death by , Inability to cut down
overdose , Stimulant use takes up a lot of time
, Cravings to use stimulants
, Stimulant use affects responsibilities
64
O Using stimulants despite social
problems
O Giving up important activities for
stimulants
O Using stimulants in dangerous situations
O Using stimulants even if they worsen a
problem
O Becoming tolerant to stimulants
O Withdrawal symptoms
• Mild = 2-3 symptoms, moderate = 4-5
symptoms, severe::::: six symptoms
(...____ T_R_E~_~_M_EN_T__ )
MEDICATIONS
• Modafinil (stimulates, reduces cravings) Figure 104.6 An individual with a perforated
nasal septum secondary to cocaine abuse.
Cocaine causes vasoconstriction and
PSYCHOTHERAPY ischemic necrosis. The hole has been closed
• Motivational interviewing, peer-support with a translucent silicone button to provie
programs structural support.
WITHDRAWAL SYMPTOMS
M\LD SYMPTOMS WORST S'l'MPTOMS
' ,.,
MOSTLY P~YC."iOLOG.ICA\.. MH.ll l-l"SITUA\. U.S(
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( o- P,E;M)
65
~E.E:~ PE.RSOtJ PI-IYSICALI..V SAH.
Figure 104.7 Illustration showing some of the recommended approaches to immediate treatment
of someone experiencing a cocaine overdose.
OPIOID DEPENDENCE
osms.tl/o ioid-de endenee
66
O Using opioids despite social problems
O Giving up important activities for opioids
( T_R_E~_~_M_EN_T
)
Using opioids in dangerous situations
O
MEDICATIONS
O Using opioids even if they worsen a • Naloxone (blocks opioids), naltrexone,
problem methadone (opioid for maintenance/
O Becoming tolerant to opioids tapering consumption), buprenorphine
O Withdrawal symptoms
• Mild = 2-3 symptoms, moderate = 4-5 PSYCHOTHERAPY
symptoms, severe=::::: six symptoms
• Motivational interviewing, peer-support
programs, cognitive behavioral therapy
OPIO\t>S
L BIND D?IO\D ~E.C..€.P10?-S iVI -lv.e
OPIUM \'OPPV 814\\Ni 61 Tll.f\~l > s SPINAL C.01l0
~ * ftJDOC:iE.NOUS Boo'i
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--~ "II £)(06WDU5 "-' J"''('I'\ t.t-JV IROi-JN\£tvT
MIL)l.'I
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( L HtP.OIN-+- M0\2.PHINE.
~ L F6.tJTA1'lYL l ~
SLOl,Jf.ST lNuE.STION
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FASTE.(l. INHALAT\OW
1
I FPST(STj
l-rv\O!>i PISSOC.IAlEO
w,l~ ~£1.tJMl.D P~HWA'I
Figure 104.9 Illustration showing the ways opioids are most commonly self-administered by
people with opioid use disorder.
67
TOBACCO DEPENDENCE
osmsJl/ -lo \>o.eeo-depe nde nee
, Using tobacco in dangerous situations
( PATHOLOGY & CAUSES ) , Using tobacco even if it worsens a
problem
• Inability to feel "normal" without tobacco
, Becoming tolerant to tobacco
use (nicotine)
, Withdrawal symptoms
• Tobacco use disorder: maladaptive pattern
of tobacco use • Mild = 2-3 symptoms, moderate = 4-5
symptoms, severe = ~ six symptoms
• Tobacco= depressant, stimulant
• Continued tobacco use causes tolerance
O Nicotinic receptors become less
sensitive/neurons have fewer receptors
(downregulation)
O Must use more to feel euphoric (positive
reinforcement)
• Withdrawal
COMPLICATIONS
• Heart attack, stroke, peripheral vascular
disease, pulmonary disease, cancer (mouth,
throat, lungs, bladder, pancreas, uterus)
(__ SI_G_NS_&_SY_M_PT_O_M_s_)
• Increased tobacco tolerance
• Upon withdrawal
° Cravings, irritability, anxiety, anger, poor
concentration, restlessness, impatience,
increased appetite, weight gain,
insomnia
OTHER DIAGNOSTICS
• ~ two of following
° Consuming more tobacco than intended ( T_R_E~_~_M_EN_T
__ )
O Inability to cut down
O Tobacco use takes up a lot of time
MEDICATIONS
• Nicotine replacement therapies (gum,
° Cravings to use tobacco
sprays, patches) to taper dose
O Tobacco use affects responsibilities
• Bupropion (antidepressant; reduces
O Using tobacco despite social problems cravings, withdrawal symptoms),
O Giving up important activities for varenicline (reduces cravings, enjoyment of
tobacco tobacco)
68
PSYCHOTHERAPY
• Motivational interviewing, peer-support
programs
OTHER 1NTERVENT10NS
• Switch to electronic cigarettes
1" Plt'.A~iE
'f A-t1'£~Tlo~
't f'\(tJ"fAL P1ZCK£~~1tJCa
't \.Joflk1~C. t'\(,-\oQ."1
Figure 104.11 Illustration showing the effects of nicotine on the brain after binding to nicotinic
receptors.
Figure 104.12 Illustration showing the half-life of nicotine, which can lead to chain smoking.
69
Severe confusion, stupor. lapses of consciousness.
vomiting, seizures, respiratory depression, Fomepizole
bluish, cold, clammy skin
70
NOTES
71
c SIGNS & SYMPTOMS ) c
MEDICATIONS
TREATMENT )
• Bruising, cuts, sores, burns or rashes;
fractured or broken bones; damage to • Sexual abuse: may require emergency
internal organs; failure to thrive contraceptives or STD prophylactics
• Anxiety related to the abuse
• Dissociative reactions PSYCHOTHERAPY
• Depression • Focus on screening and prevention;
• Aggressiveness may include symptomatic treatment or
• PTSD psychotherapy (esp. cognitive behavioral
• Sexual abuse therapy)
° Fear of or anxiety towards sexual
activity OTHER INTERVENTIONS
O Increased risk of suicide • Medical intervention, as needed
O If appropriate, physical symptoms (e.g. • Referral to protective services for legal/
physical trauma, STls, UTls) social support
c
OTHER DIAGNOSTICS
DIAGNOSIS )
• Based on individual history and presence of
above symptoms
POSTTRAUMATIC STRESS
DISORDER (PTSD)
osmsJl/PTSD
( PATHOLOGY & CAUSES ) (__ SI_G_NS_&_S_Y_M_PT_O_M_
• Memory of past traumatic event ----. • Psychological
recurrent mental, physical stress , Nightmares, flashbacks, intrusive
O E.g. car crashes; sexual abuse; military thoughts
service; natural disasters • Behavioral
• Psychological svrnptoms e- behavioral • Avoidance of situations/environments,
changes hypervigilance, hyperarousal ----. trouble
• Individuals might self-medicate with sleeping, general irritability, emotional
substance use outbursts
• Neurological factors • Children less likely to show distress; often
O Dysfunctions in hypothalamic-pituitary- use play to express memories
adrenal axis/endogenous opioid system;
deficits in arousal, sleep regulation;
family history
72
• Disturbance cannot be better explained by
( D_IA_GN_O_s,_s) another condition/substance
OTHER DIAGNOSTICS
• Exposure to traumatic event (..____ T_R_E~_~_M_EN_T )
• Intrusive symptoms
O Recurrent, distressful memories, dreams MEDICATIONS
O Dissociative reactions • Antidepressants, esp. selective serotonin
reuptake inhibitors (SSRls); anti-anxiety;
O Distress/physiological reactions in
sleep aids
response to stimuli
• Avoidance of associated stimuli,
psychological (e.g. memories)/tangible (e.g. PSYCHOTHERAPY
places) • Exposure, group therapy
• Negative changes in thoughts, feelings
• Increased sensitivity to event, associated OTHER INTERVENTIONS
stimuli
• Manage substance use
• Disturbance lasts> one montb -e distress
in other areas of life
(__ SI_G_NS_&_SY_M_PT_O_M_s
) Moderate = ;;;: two changes O