DRUG MECHANI INDICATI CONTRA- SE/AE NURSING RATION

ORDER SM OF ON RESPONSIBI ALE

INDICATIO
ACTION LITY
N
Alkylating drugs  Various  Contraindica SIDE EFFECTS: 1.Assess patient’s VS, *Low blood
GENERIC appear to act tumors, ted in esp. BP and O2 stat pressure, or
NAME: independently of especiall patients 2. Encourage to decrease in O2
a specific cell- y those hypertensiv increase electrolyte stat can cause
Carboplatin cycle phase. highly with e to these and fluid intake dizziness
Oxaliplatin reactive, they large drugs. 3.Provide bulk fiber *To prevent
primarily target volume  Use on patient’s food like dehydration
Thiotepa nucleic acids and and slow cautiously in grains and cereals. due to nausea
capecitabine form links with cell- patients 4. Encourage patient and vomiting.
fluorouracil the nuclei of turnover receiving to rinse mouth with * This will help
Cisplatin different rate other cell- saline water the patient’s
molecules. This destroying 5. Advise patient to stool to thicken
Cyclophospha allows the drug to drugs or stay in bed and rest *This will help
mide cross-link double- radiation. 6. Monitor sleep in soothing the
stranded DNA and  May cause pattern of patient irritated
Temozolomide to prevent strands fetal harm if mucous
from separating administere membranes.
CLASSIFICATIO for replication, d during *To prevent
N: which may pregnancy. falls due to
contribute to Females and swelling of the
Alkylating these drugs’ males with feet or lower
drugs ability to destroy female legs
cells. These partners of * This will help
polyfunctional childbearing to assess the
compounds can potential patient’s level
be divided should use of fatigue
chemically into effective ADVERSE
five groups: contraceptio
nitrogen n during EFFECTS:
mustards, therapy.
ethyleneamines, Consult Bone marrow
alkyl sulfonates, individual depression,
triazines, and drug chills, diarrhea,
nitrosoureas monographs fever, flank
for pain, hair loss,
contraceptio leukopenia,
n nausea, redness
recommend or pain at the
ations after injection site,
final dose of sore throat,
drug. swelling of the
Women feet or lower
should stop legs,
breastfeedin thrombocytope
g during nia, secondary
therapy leukemia,
because infertility, and
drugs vomiting.
appear in
human milk.
Safety and
effectivenes
s of many
alkylating
drugs
haven’t
been
established
in children.
Older adults
are at
increased
risk for
adverse
reactions;
monitor
closely