A:

 Animal cruelty:
 Endangered species exploitation
 Animal testing and experimentation
 Assault and violence:
 Gang violence
 Domestic violence against men
 Hate crimes against minorities
 Child abuse and neglect
 Antibiotic resistance:
 Lack of new antibiotics development
 Post-surgery infections

B:

 Child labor:
 Child labor in agriculture
 Child labor in the fashion industry
 Child marriage:
 Early and forced marriages
 Impact on girls' education
 Climate change effects:
 Ocean acidification
 Loss of coral reefs
 Sea level rise
 Increased wildfires and extreme weather events
 Corruption:
 Political corruption in developing nations
 Influence of money in politics
 Cybersecurity threats:
 Ransomware attacks
 State-sponsored cyber-espionage

D:

 Deforestation:
 Illegal logging
 Impact on indigenous cultures
  Domestic abuse:
 Emotional abuse
 Gaslighting in relationships
 Psychological abuse
 Financial abuse
 Drug abuse and addiction:
 Methamphetamine addiction
 Prescription opioid crisis
 Discrimination:
 Racial profiling
 Workplace discrimination
 Ageism and ableism
 Religious discrimination
 Discrimination against people with disabilities

E:

 Environmental pollution:
 Soil contamination
 Microplastics in the environment
 Air pollution-related diseases
 Impact on marine ecosystems
 Ethnic cleansing:
 Rohingya crisis
 Uighur genocide
 Epidemics and pandemics:
 Antivaxxer movements
 Ebola outbreaks
 Zika virus outbreaks
 Drug-resistant malaria

F:

 Food insecurity:
 Childhood hunger
 Food deserts in urban areas
 Forced labor:
 Forced labor in supply chains
 Human trafficking for labor in agriculture
G:

 Gender inequality:
 Gender-based violence
 Workplace harassment
 Genocide:
 Bosnian genocide
 Rwandan genocide
 Gun violence:
 Mass shootings
 Accidental firearm deaths
 Gang violence:
 Urban gang violence
 Recruitment of young people into gangs

H:

 Hate crimes:
 Islamophobia
 Anti-Semitism
 LGBTQ+ hate crimes
 Religious hate crimes
 Human trafficking:
 Child trafficking for adoption
 Organ trafficking networks
 Forced prostitution
 Human trafficking for labor
 Health disparities:
 Maternal mortality disparities
 Access to healthcare disparities
 Global healthcare inequality
 Lack of access to mental health services
 Homelessness:
 Lack of shelter and housing
 Mental health issues among the homeless

I:

 Income inequality:
 CEO-worker wage gap
  Gig economy exploitation
 Wealth concentration
 Infectious diseases:
 Zika virus outbreaks
 Drug-resistant malaria
 HIV/AIDS pandemic
 Tuberculosis epidemic

L:

 LGBTQ+ discrimination:
 Conversion therapy for LGBTQ+ youth
 LGBTQ+ homelessness
 Workplace discrimination against LGBTQ+ individuals
 Landmines:
 Long-lasting impact on post-conflict regions
 Civilian casualties due to landmines

M:

 Mental health stigma:

 Stigmatization of veterans with PTSD
 Mental health crisis in prisons
 Lack of access to mental health resources
 Nuclear proliferation:
 North Korea's nuclear program
 Nuclear accidents and radiation exposure
 Risk of nuclear conflict
 Proliferation of nuclear weapons
 Child soldiers:
 Use of child soldiers in conflicts in Africa
 Rehabilitation challenges for former child soldiers
 Forced recruitment and use in armed conflicts
 Trauma and psychological impact

P:

 Police brutality:
 Excessive use of force against peaceful protesters
 Militarization of police
  Racial profiling
 Police violence against Black communities
 Political corruption:
 Nepotism in government
 Erosion of democratic institutions
 Election fraud
 Bribery and embezzlement
 Pollution:
 Air pollution-related diseases
 Impact on marine ecosystems
 Contaminated drinking water
 Soil pollution and its effects
 Poverty:
 Global poverty in developing countries
 Working poor in developed nations
 Cycle of generational poverty
 Urban slums
 Privacy invasion:
 Facial recognition technology
 Data breaches leading to identity theft
 Mass surveillance programs
 Invasion of personal privacy
 Government surveillance programs

R:

 Racism:
 Systemic racism
 Police violence against Black communities
 Indigenous rights and land theft
 Refugee crises:
 Rohingya refugee crisis
 South Sudanese refugee crisis
 Forced displacement of people
 Refugee camps and living conditions
 Religious persecution:
 Persecution of the Baháʼí Faith in Iran
 Persecution of Christians in North Korea
 Persecution of religious minorities
 Destruction of religious sites
S:

 Sex trafficking:
 Child sex trafficking in Southeast Asia
 Online sex trafficking platforms
 Exploitation of vulnerable individuals
 Human trafficking for the sex trade
 Species extinction:
 Rapid decline of amphibian species
 Impact of bushmeat hunting on wildlife
 Loss of iconic species
 Ecosystem imbalances
 Substance abuse:
 Fentanyl overdose epidemic
 Designer drugs and synthetic opioids
 Impact on families and communities
 Overdose deaths
 Surveillance:
 Invasion of personal privacy
 Government surveillance programs
 Facial recognition misuse by authorities
 Mass surveillance in authoritarian regimes
 Data mining by tech companies
 Sweatshops:
 Child labor in the fashion industry
 Dangerous working conditions in textile factories
 Exploitative labor conditions
 Low wages and poor worker rights

T:

 Terrorism:
 Acts of terror and violence
 Fear and instability in affected regions
 ISIS and its global reach
 Lone wolf terrorist attacks
 Torture:
 Violation of human rights
 Psychological and physical trauma
 Torture in secret detention centers
  Torture in the context of armed conflicts
 Child abuse:
 Physical and sexual abuse of children
 Long-term psychological impact
 Child abuse in religious institutions
 Child exploitation through child pornography

V:

 Violence against women:

 Domestic violence
 Honor killings
 Female genital mutilation (FGM)
 Acid attacks against women
 War crimes:
 Targeting civilians
 Use of chemical weapons in Syria
 Destruction of infrastructure
 Violation of international humanitarian law
 Child exploitation:
 Child labor in cobalt mines
 Child exploitation in the cocoa industry
 Child labor in dangerous conditions
 Child trafficking
 Voter suppression:
 Suppression of minority votes in the United States
 Election interference by foreign governments
 Undermining democratic processes

W:

 War and conflict:

 Ongoing conflicts with civilian casualties
 Destruction of infrastructure
 Civil war in Yemen
 Humanitarian crisis in Venezuela
 Water scarcity:
 Lack of access to clean water
 Water-related conflicts
 Water disputes in the Middle East
  Drought-induced food shortages
 Wildlife poaching:
 Rhino horn trafficking
 Ivory trade and elephant poaching

X:

 Xenophobia:
 Hate crimes against immigrants
 Discrimination against refugees and asylum seekers

Y:

 Youth homelessness:
 Homeless youth living on the streets
 Lack of resources and support for homeless youth

Z:

 Zero-day exploits:
 Cybersecurity vulnerabilities
 Exploitation by malicious actors