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Eur J Obstet Gynecol Reprod Biol


. 1988 Jul;28(3):171-8. doi: 10.1016/0028-2243(88)90027-5.
Umbilical artery Doppler flow velocity waveform: the outcome of pregnancies with
absent end diastolic flow
F D Johnstone 1, N G Haddad, P Hoskins, W McDicken, S Chambers, B Muir
Affiliations expand
PMID: 3208963 DOI: 10.1016/0028-2243(88)90027-5
Abstract
We have studied doppler recordings of flow velocity waveform of the umbilical
artery in 380 high-risk pregnancies and 160 patients with uncomplicated
pregnancies. The results were not used in clinical management. In 24 cases, all in
high-risk pregnancies, there was absence of end diastolic flow (AEDF). Four babies
died, 22 out of 24 weighted less than the 5th centile for gestation and 20 were
delivered by Caesarean Section. With only four exceptions, all fetuses showed other
evidence of antenatal fetal compromise, though this was delayed in some cases for
up to 24 days. AEDF does not appear to prejudice neonatal outcome. All six babies
born weighing 750-999 g survived. In addition, 4 patients continued their pregnancy
for 3-6 weeks after the first doppler with AEDF. Only one of the 4 developed other
evidence of fetal compromise and two had vaginal deliveries. In our experience,
AEDF is found only in abnormal pregnancy, and is a very serious sign of likely
fetal compromise. It is an indication for extremely careful surveillance but not
necessarily an indication for delivery.

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MeSH terms
Blood Pressure*
Female
Fetal Monitoring / methods
Humans
Pregnancy
Pregnancy Outcome / physiopathology*
Ultrasonics
Umbilical Arteries / physiopathology*
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