Structure Of Amines Preparation of Amines Reduction of Nitro Compounds Ammonolysis of alkyl halides Reduction of nitriles Reduction of amides —|Gabriel phthalimide synthesis | |Hoffmann bromoamide degradation reaction Basic Character | | Alkylation/Acylation Carbylamine Reaction] Reaction with Arylsulphonyl chloride Reaction with nitrous acid)(HI, gmp) [Rrefr: Amine > Amina coh be Considmd od darived'vah of tnmonio.. NH & - - i » REN RoR y BEN B ae pion 1 Aina Xhrin & & Tupac Nam. i— = Alkan, -¢ + Amine = Adkanamin, © BNNs) > Por due amine gob AdKon, 4 diohvinn > Common Nam i= ‘ cd on Naw i= Akkylarmine. Chen) be & ve KEN Ri NOW wk tH “eaten Reanfle— CHATCH TN, TL Bthaami fp sorte = Ye Aaalanarine TL Biaybatnine p+ comme em (Beytratybon) 3 HCO NN, g ye Roajgtonns TL Pajan-t- amine} soe 4 . eH NAO 4 Cig CH My : Laoprsiybornime c Prana arsine] ti —” mh NeMatiyLathananie os onty ar oF + pe n= dinthyathararsine« yukiat fay oH ENeethy Ne mnathyl chap anins Tt pkeaat GD Si Ae teap =a em ton ee ic Qs L242 2| ak > Ww mnattyLethanasine 2 CH CT NA Oy L ov 2 + ‘i RR ON HT T= NG Ruk— 3- ena bo oie + Yoas atch © > Sartor function gamh malta 3° self detest Ror Taming. ef, junior fasutimad graah one ase Pre of Het gh tA tn + SePrinchutan-l-oot ten? Contacts) NH. S& My x ahd junter fancdoweh qe ase trad 04, wt * > Whwinobwdenad eRe heey 1 Rint tsi at= + Poiline (IN 4 Bremvonthinn ce Whe ' OTE, ae Pinodslume CT odhe- Tolaiaing] 5 I anette Doenzenarni at, eka (Sel) 4) Radushin nite confer tt = o™ — eo os wld» os x “ @ mete tbyk foide = %, BS, nerds Beasking eh bed y arama + | 3 ody f. TeeNihy a ably felts BAY Bow + Ket, #4 —t RBs > KAP KE 8 2 «2 9 Strong bend Se tough te beak» 1 cok soy nye ac apa t Nike % a > ii 2 Ee, as 2 keX en Rae pm 1 = ina sets BP int " 4" © Reduatin f Wha RCE ge ben\, Na CH) [CalisoH) " Qaduakin of anid -+ poker, ZEB, Ree eases) “) Hao & Rovide Rinins ° ~ orion ORAS or Hy Ovo + take. Outvw _ EO Sie ET OMe Poatacts | cosesens] (01)©@) Gaberat phthalimide Qyntuns —2 ( for prebaratin of 1» Aloinu) f ath") “ © & zee , y be kott i So Oo SS ore LA, S ot . ¥ V7 Politic , only abiphei oblyl gop = (cask 2019} E33) becoute in avorahis (an plant) twite Prop Hog daub bord charache Hydro [rrottean] (gaan) = An bork with faloges- ° © Hoffrrann bremamide —dagradstion teach’! oo ftom ning \ gedadion 889 Loxton yess . es an) RAN, ‘ poten, + Pe. EO we4 $ Nao + RNABe +AHK9 Amide patie cry tao on, CHBDR GH Har CNH, utanamide Prrobanarnine ‘Buda mide - @& Lo Or Heo or anil. rn Berzamide. as\3— Phyrical fo a Lower almins are doluble an walter because Soy can form Ayaeoyey boonding. vith wen Water Wale cola: , wees % ” . Ranh Ay Re NHR nck 2 Pred . PY VC" \ A Umm fy STN K 6 Hebandiny, —= 7 Bb tt 2 Salbity, 3 Reemohis otmina (auch of onibiee) gre ingeluble in water due do Jang, Aydroemby ort Chow intrnuve uith ust) - Jeoseae] GD AB Binie Op Ae Amine 7 FP Beste Boiking Pei —+ ovdn of OP aye fT pmetatin LoyeetS > Thin as become of onder of extent of He bending RED Let male 2 ORThin anfurmolecidae aasottabin ig move dn primary, atai nh ean fn 2% arminut Od Hare are deo Lydregen atoms are aveilable, for Ayarngen bo formalin in Extent eb : wage gene ogee NAY . : Hoban in tt Rony DY & aw a) koat if e . TH yt ‘ No Hydvgen bod > Qecayse 3° ming Rave ne Aydrogen bod betwun logue Jed Ataf So, primey, amind fave fiyhor 0-0: [ease acu (y 1 waenind f ’ Foc example Gs Pet Reopanaintn CHET ASN, 2 Nts thar (3 < [easeaens) > rR RS, = n— Ri, x2 Got) + Baye Nodure of amine aa due do Ske Loup! Bastaky. i4 referent by Ke” aluch attend Wt de sad ony L phy =~ lop he fon ky A LE Pke > @ whee = dur do atobility, aR, with waht " do ng, eqikleion comand firvetin (H) te igo tw atgt © 4s woe Kon cadin (W) « ‘ —> — Alkanaiir NA. Ammonia. > Maan, Hat, Riphakic otines Ora at rege baced Han ofemeiqgs = CH e — Hn, : a alton > onde of barity, in gen plate 3 Bpiin Gk by Ht ctfech an Bare i 0 A on savet> Ky 2 Sho nie? he, 7 So > nijeWore Solvodin => More Stab, ion ~ Ky ~ un > WH —_ + Tpathi 2¢! — Dea x Tpathi 20 He Kee 2 D> aD LTD Peni, Gna [phate > Baricty of aims in ony PAE Move ordin Jb ned dewe in_ avant Wrediowe The gubshtubed otwmanivin Catia gue Atabibirad not only. by adadron walrating effect of alltgl graf C3) bur alao by Adlvatin with ater rnelecal + He dm Aoving mee Aysmgen boda GWA ater Trobe, are peer Adah + Se mee will be Kip volun fee Haak ini na rd \ Rents + Kyo < RONG Hm ore t WH—beda more « Rowen tHe SR heneonts R 1e 2 Helena, “OH. a & \ \ a Namge = Roh ® 6 we \ Kes Gan > Gin > Cate NH DMM, 7 23: L.NM2 Batre a Ke: @3),"" > CH NI? (ts), Dung 2 STNG Seth & { ay sa” S pats 23) © Dold NHy ee 1 Lol Leone pate of nikagen on ammonia, JA nm ant SME avilabiefas Jrotenatin: Got in awibin — Ggrnth pate a” Jom pois ta wok 2atily oveidehWe dur ko rater, With boven ¥rge— > Bariety Ord (kn) CHy> Nin, eins CE coman] @ Locolisch tow priv Dalocalited Lb, So nok AN in aC available foc proton Sok: & " : oe © ” oO > Coy ar eft [ease auth, ae Soret ° & four ; Cavers (fore 7 oO > G + easeae¥] @ Localiged Jem petocohi cad Len pate So dow pair 6 wk available for prohonaction» — we & CHyprn, <7 NaH a . « aannaees ea of abylamp: So nek avaiable reer . at afte Y nih ny, Ne / — Bhidron destin ron — ° > O>? ° the making pret Se GD aduker away at ritrezen oni =nos|—cr | CFs So, it con 2atily dete Sow [ai Hong |-cas | 80% eae opt Nth Nia @ 7 eo) y @ + [egséoes p-Tolwidinn Prin Pony —Ditwanihivn & My Noy, sasie) { (eae an of oi Caan of ER neh? egletton of putick |" i as 12 [ae Bois cot ° toe Sega \s gga Be or gle bee 4 > pabl . a : Powmak of Mydvoyn by cry t= + Redifion ot ne D>= “Ne ° 7 + ey ¥ Coen, 4 S 4% ° ‘ faod Sue — oy + ck ef en, Pham + Oty A N= Phanytathanarcd [ Rectaniide ° Chg- ft (oy nae b= ony 2 Re ED) Carbylamin, Reachion — [Tat for tt Amina t Present, of 2 Hyadeegtn 4 — 39/ 3% Aminu do nod give Hea reachin + neceoyy T j + 2ka + Iho a Ally iaacyenide (Fea Amand) be > RENK, F CHUg } IK a us 7 4, ® - 4 Fut Js also called oe AOR, Se COLT NE Leave and Tascyarics tuts a My > By amy Yor reaction Caagt] we Can dkadingarish (ur ona amine), and (Ye an 38 atrind) + eng, Sits No resthon emg NM Ma rat (2° Pind \e Qe Pres) @ eer I Poud Stalling: Cuts NC) Hg NH, ‘ A) can be — Aw lacy RyYylamine (nr) ond pretty (ao . Aralliny diiatingus das My cartoyh amin godt 18 Peat Cots) giv eu Amalling na, and Kot * Trai no ch (y > Awibin < N- mthylanlin 2 Site NG Fou mall wy Ss oy ny oO kom Tegse-anod (im, Years GH) ower oy 22g Qo teachin Y ken— Reackm with HNO, LT Nites ped J —; jb Nite Red i o© Primary abiphabic abwintd 2 Ren, + HNO, — > Evobihim of niteogen: ori CJ © freemehic: Arming —! Wag two, NE” YJ Ww nave, He 7 (Bevzndvazeriom Hest) Saat — Broma’c Ord abihahe Onin Cah be ain ngs chad, by above sptachion* for epic: [Ri Bs] gyms A» ¥E* guy case aoise [2018 cask aor’ Newer cide @& wh, sm ute on nae ot eS Ot ey Cask aise Ge) gree OW ynyt (Pees) Banaylarine: « onk=s Hiinabeeg Reged —? Gerenuniien oot @ chloe» > Reatkion with Hinsbag Raagest <3 at Amine -i i ay ot ire = iD Sohtta in Not C86) @: —, {easeacis] Ge) ne fihytberzersslfbwne yy §-CS) . af affine Oe a SD ° ~ i Lo Neo Not Sdube. in olkall becaute Hart ds RO acdc tydregen * 3° Arai, ee ~~ re a-[@ Ae Ne Raadhin + Phe vtaget con be uted do distinguich L°( 44) 7° Amints -Ebebroptibic Substitubion Ruthin — Gs ey —_ nis » > =NWg grab do ovtho —para direding. ond poverfol aechonding, gre: oo — ew, _S* TL demata ehietren chuntity- ey Jo venzoa ary L vsnye bem] me acti, for electro htC S Yodtion« In vrasenating atruthyre , OVS Chorge in preeant ot oithe od pars position « Phat urky electrophilic Avibatitation Jakes plea mere radia in ayomedl’s wins than bozo: — Udate acc) (te) i” wh wm sik © Bremination :— Sele “ae 2,4,6 “Tabremeaniine -3HGe or ike Oy Ni te BS Ayer Han thet of, nt, Bra + become Jow pair of “ dig Aowd obte with =H os paiveing, affect qd —nirt Oy grok sa 7 °° in gritos crue BL gmp So SE on wt qcivehy bora UNE nS ® ny wi o NH, ® Suphonetion ;— os Hatoe os a & ° o We hes, son rite , oh Spies = . wa pridin, dom pot undlago Péadtd coffe Wain fm ee qua do folk febadim with Pilly» Rae ade OS a. o Lawis awe Se Arenge da actitingg gre fer fees eacion: aac yen gawd? palti nerge}> TAD v ogeeComplate He following veechin | «fas Nace jt. &® Cup che chs Cig CEN ope CHS CHM, f= (a) [ah indus 200] he NMafo i On -! conus, : CHS con CH= ENN, a Cig NM Cag NG © ® © Usb eng SYS eye BAM Cy Cr Ni | evsinet Cig OH -NE [atte aoe] ED ap G Salt, caus oy — GH) ose 20] Nech 2b in aromakis Compond AL Cor | Naja, oi Ny, \ Me & a a & w <= © eee), ory -o Tease sors] $5] fm trromatte. combond A Nita Love : a ° Q—ot Genramids SaAkoH Benaoie ned . Cea) oak asise] Ge) ouDiazonium Salts = /~*diazonium group General formula : (Rene Aryl Group < * ee > - *_,€1" Br” / HSO; / BE; Neen ot (Benzenediazonium Chloride) (Benzenediazonium hydrogensulphate) Methods of Preparation : Diazotisation : ‘The conversion of primary aromatic amines into diazonium salts is known as diazotisation. 1) Primary aliphatic amines “° of R—NH, + HNO, —— R—N&N Primary aliphatic amines form t highly unstable alkyldiazonium salts, NaNO, + HCI 2) Aromatic Amines :- NH: NEN 2 OF Aromatic Amines mer + HCI (Benzenediazonium Chloride) (Aniline) Salt Primary aromatic amines form arenediazonium salts which are stable for a short time in solution at low temperatures ( 0-5 C ). Reason for stability of arenediazonium : Resonance phenomenon N&N Om oePhysical Properties : N%ew 7 7 Colourless erystalline solid ci “—> Itis readily soluble in water and is stable in cold but reacts (Gea notieraciun Cherie, with water whee warmed, Itdocompess easily in the dry Nu N BF ——> Benzenediazonium fluoroborate is water insoluble and stable 4 at room temperature, Chemical Reactions Reactions involving displacement of nitrogen Gattermann Reaction Sandmeyer reaction l q N CwHCl a CuBr Other important reactions : F ° Heat a + BR, + 3 “47 N&n NeN I BE, Oe 4 7 + KCl +N, NO, NaNO, N, + NaBE, + =oof NaN H H,PO, + H,PO, + HCI + Ny H,0 H CH;-CH,—OH Q + CHpCHO + HCl + Ny OH + HCI + Ny Coupling Reaction : OH ne N=n—{~ oH © + ‘OH Base Phenol p-Hydroxyazobenane ( (ranee Dye ) NH, N&w . nov) ai H Oo * Acid or Aniline p-Aminoazobenzne ( Yellow Dye ) ‘The azo products obtained have an extended conjugate system having both the aromatic rings Joined through the -N=N- bond. These compounds are often coloured and are used as dyes