Sick Population: Unit: Family RA 7610-Anti Child Abuse Law (Do Not Confuse With!)
Sick Population: Unit: Family RA 7610-Anti Child Abuse Law (Do Not Confuse With!)
CHN DEFINITION:
ANA: Synthesis of public health practice and nursing practice towards preservation of health
Ruth B. Freeman: It is a service rendered by the professional nurse to the levels of clientele in
different health settings.(Subspecialty)
1. Home setting > PHN
2. Clinic setting >PHN (RA 7305) magna carta for public health workers. [Corazon
Aquino]
3. Work Setting > Occupational HN (RA 1054)
4. School Setting > School HN (RA 124)
Other Subspecialty:
1. Home Health/ Home Care Nursing - Attending in the comfort of the patients home. [Ex.
Compliance to medication administration, wound care, services provided by the hospital]
Sick population
2. Community-Based Nursing- providing hospital care in the community [ex. Oplan Tuli
program]
3. Correctional Nursing- Provided in the prison
● Forensic Nursing-
Trace evidence- Evidence
4. . Parish Nursing/Faith Nursing-
OLOF Model:
● Political Factor: Safety, Oppression and People empowerment > SOP
● Behavior- lifestyle of the people
● Heredity- Parts of Genetics already (Genetics, familial disease)
● Socioeconomic- EEH (education, employment, Housing)
● Environment-
● Healthcare Delivery System-
Devolution/Decentralisation (RA 7160) Local Gov. Code of the Philippines- power is in
the LGUs (Focus of the delivery of service)
Unit: Family
RA 7610- Anti child Abuse Law (Do not confuse with!)
Services:
1. Promotive
Primary focus: Health Promotion > through health teaching
Primary Role: EDUCATORS (alert!)
Other fxn:
"RT PCR MO Nurse"
Role Model
Trainer- train BHW/CHW/village workers/auxiliary workers
Planner- implement program
Coordinator of services-
Recording and Reporting- FHSIS (field health service information system) Alert!
Manager/Supervisor- Midwife
Organizer- COPAR (People does the research) self reliant!
Nurse- Care Provider
2. Preventive
3. Curative
4. Rehabilitation
FHSIS-
Record keeping- BHS/RHU-
Daily >Monthly done by: (Midwife) >PHN (Quarterly report) Rhu level > Provincial Health
officer/City Hx officer> Regional health officer (Quarterly report)
Cont. Of definition:
Bailon Reyes- A nursing service provided outside a purely curative institution (Hospital)
2. Family- unit of service and the focus of nursing care; main caregiver in the primary level of
care.
-Groups of people sharing common interest binded by law and by blood.
Fxn. Of the family :
● Socialization
● Healthcare (starts at the home) IMCI (integrated management of childhood
management)- A protocol based program
Protocol of IMCI: flip chart
Assess- Classify- Mgt.
first line of drug given at RHU
Dehydration:
Severe Dehy: General Danger Sign, inability to drink and swallow, lethargic, very slow skin
pinch
Plan C (Pink): IV, NGT
Some Dehy: No Gds, eagerly thirsty, restless and irritability, slow skin pinch
Plan B (Yellow)- ORS
ORS Formula: Wt. (Kg) x 75ml
No dehy: no s/s of dehydration
Plan A (green): Continue Breast feeding, give natural juices (Calamansi, Buko Juice, Ginger
juice)
● Affection- (Family)
● Reproduction
● Economic
● Social placement/Status
3. Dyad- Newly married couple without child yet, no child in the house
*Empty Nesters- the child left the household
4. Blended- with child from previous marriages
5. Compound type- Multiple spouses (male) MUSLIM community (PD 1083) Code of
muslim personal law
6. Cohabitating- living in arrangement, not legal in the gov.
Common Law Spouse- term for living partners
7. Single parent- Death, Born out of wedlock,
8. Gay or lesbian family-
EO 209- Family Code of the Philippines
- Marriage is a special contract and a permanent union of a man and woman.
8 Stages of the Family Life Cycle (Evelyn Duval)
Basis of choosing is the Oldest Child
1. Beginning of family- married or unmarried without child
2. Childbearing Family- with child 0- 30 mo.
3. Family with preschoolers- 30 mo. -6 yo.
4. Family with schooler- 6yo -13 yo
5. Family with teenager- 13yo - 20yo
6. Launching young adult- 1st child- last leaves the family (building career)
7. Middle age family- empty nesters- retirement
8. Aging Family- retirement- death of both spouse
Malnutrition:
● Vit. K- night blindedness, xerophthalmia (Xerosis- inability to produce tears)
● Iron- Iron deficiency anemia
● Iodine- Goiter, Mental Retardation
DOH programs:
1. Micronutrients supplementation program
Target: 5 yo & below
Strategy: Garantisadong pambata Gp1- April, Gp2- Oct. (Every 6 months- Vit. A
supplementation sched)
Alert!
Vit. A supplement-
<1yo = 100,000 IUs (6mo-11mo) "once"
>1yo= 200,000 IUs (every 6 months- 5yo)
Mother:
Prenatal- 10,000 IUs (2x a week) (4th mo/2nd trimester)
Postpartum- 200,000 IUs (once) (1st 4 weeks post delivery)
● Adolescents-
*STI(No Symptoms/STD (with symptoms)
HIV- STI
-Dormant stage (10years)
STD- Gonorrhea (more severe) [morning drip], Chlamydia
● Elderly- Aging
Chronological Age- Age by number
Older Adult- 65 yo & above= 4% (PSA)
Population pyramid- Expansive type of pyramid.
-Wider base and narrow top- Younger population (increased Birth Rate, Fetal Rate, Mortality
Rate, decreased life expectancy)
-DOH- projected life expectancy 2020-2025: Female- 75 yo, male 70yo
Others types:
Rurban- mixed of both
Suburban- Gilid ng urban community
Metropolitan- center
Sept. 25, 2015- united nations conference (UN HQ, Nyc- 193 countries)
Title: Transforming our world the 2030 agenda for sustainable development
Poverty- possible
Hunger- possible
Health and wellbeing- (alert)
Education
Gender equality- not health related
Clean water and Sanitation- possible
Clean Energy
Decent Work and economic growth- possible (shortage of healthcare workers)
Industry, innovation & Infrastructure
Reduce Inequalities- possible
Sustainable cities
Responsible consumption- possible
Climate Action- possible
Life below water- possible
Life on Land- possible (emerging infectious disease
Peace- possible
Partnership for goals- possible (key in the progress of primary Health care) Multisectoral
approach
Stakeholders- play a role in the success of programs
Sanitation-
PD 856 (Sanitation code of Phil)
PD 825 (Garbage Law of the phil)
Garbage Collection: Curbside collection
Water Sanitation:
Sources:
Level 1- point source
(250 meters; 40-140 L/min; 15-25 households)
Ex. Covered well
Level 3- Water Works system, indiv. House connection; paying the consumption of usage
(Cubic centimeter)
Ex. Household Taps/Faucets
Toilet Sanitation
Level 1- Non water Carriage Toilet; pour flush type
Level 2- Flush type with septic tank
Level3- Flush type with septic tank with treatment facility
Food Sanitation:
Sanitary permit: Sanitary inspectors/engineers issued by Municipal Health/ City Health issued
by (mayor)
Types if Hazards:
Physical: healthy working environment (Temp, ventilation, humidity)
Biological: The presence of bacteria, virus, infectious agents
Chemical: Toxic gas, fumes
Mechanical: Safe machine and using PPE
Psychosocial: Relationship in the working environment, healthy working environment
PHN Hx:
-Babaylan/shaman-
-Introduce health to phil: Spaniards
Spanish Era
● 1st hospital: Hospital Real (The Royal Hospital) caters to Spanish only in Cebu
● 1st hospital for Filipinos- Hospital de los indios naturales (The hospital for the dumb and
the poor) in Intramuros manila [Destroyed by fire]
● Hospital de San Lazaro- donated by the rich chinese man to the filipinos
● 1st university that offered medical course (2 year course, fundamentals of medicine and
dentistry) (graduates are called Cirujanos ministrantes) -male nurse/sanitary inspectors -
UST
● Maternity clinic (puericulture center) high risk pregnancy- 1st (La Gota De Leche) "milk
station" - introduced wet nursing
● Philippine General Hospital 1915- introduced public health nursing
● Board of Health- Americans; 1939- Manuel L. quezon- Commonwealth gov. (Department
of health and public welfare) 1st sec.- Dr. Jose Fabella
Roxas- separate health and welfare- DOH (oct. 4, 1947) EO 94 (kagawaran ng kalusugan) 1st
sec. (Dr. Antonio Villarama)
SETTING:
Clinic Visit:
Phase:
1. Pre Consultation Conference- chief complaint (important data)
2. Medical examination phase
3. Nursing intervention phase
4. Post consultation conference- Health Teachings - Health promotion
OTTAWA charter for health promotion- Assembly at Ottawa, Canada (Nov. 17-21, 1986)
WHO
Result: 5 action areas for health promotion
"DR. BSC"
1. Develop personal skills
2. Reorient public health services
3. Building public health policy
4. Strengthening community action
5. Create supportive environment
b- non program based- refer the situation beyond the nursing and primary capacity of
care
c- emergency case based- First Aid
● Dog bite: Wash with running water for 15 min. or with antiseptic agent (Rabies is
hydro and aerophobic)
4. Clinical evaluation
5. Laboratory Exam- Screening test
6. Dispensing of drugs- OTC drugs, Rx drugs (with prescription, DOH program) ex. TB
DOTS, HIV (ARV- Antiretroviral drug) 1st line: LTE (Lamivudine. Tenofovir. Efavirenz)
2nd line: TLD: teno. Lami, dolutegravir (milder effects)
Common drugs: CARIPPON
● Cotrimoxazole (antibiotic)
(azole- antifungals)
● Amoxicilline (antibiotics)
● Rifampicin
● Isoniazid
● Pyrazinamide
● Paracetamol
● Oresol (lite)
● Nifedipine
Principles-
Purpose and objectives; Prioritize; Plan of visit (characteristics: Practical, flexible, family) Make
use of all available information from the client
Phases-
Pre-visit phase- purpose and plan
In home phase- 1. Initiation (Knock, non threatening voice, greet, introduce yourself, observe
the environment, establish rapport, state the purpose)
2. Implementation- nsg. process
3. Termination- summarize with the family
set the next visit/clinic visit
Record
Post visit phase- return to the facility, documentation, referral
Principles:
● Minimize if not prevent the spread of infection (most important)
● Effectiveness of total care
● Save time and effort
● Avoid contamination
● Handwashing
Contents/Area:
Top- "Ganunin" wave like
Front- Thermometer and Test tube with Holder
Center- ___?____
Rear- chemicals and solutions
*All contents of the bag must be clean or aseptic
Primary- f
Secondary- reports, records, document
Data collection:
>Primary data
1. Interview- First hand, most reliable, Best method.
● Informant interview- head of the family
● Key person interview- key people (leaders of the community> brgy captain,
elderly, parish priest)
2. Observation-
● participant observation
● Rapid observation (windshield observation)- during ocular inspection/survey
3. Surveys/questionnaire- Majority of data
4. Community forum/assembly (pagpupulong-pulong sa barangay)- open meeting of
the heads of the brgy.
5. Focus group- smaller meeting 6-12 participants
>Secondary data-
1. Records review
● Census- official enumeration of the total population
>Demography- characteristics of the population
>Health indicators of the population: births, Morbidity, mortality (Vital
statistics/biostatistics/health statistics)
Post mortem- same precaution when alive, same precaution when died
3. FHSIS (EO 352) official recording and reporting system of the department of health
Components of FHSIS:
1. Treatment record- Fundamental Building block
● Individual- record of each member of the family
● Family- as whole
2. Target client list TCL- secondary building block of FHSIS "Sino -Sino"
● prenatal and postnatal
● Under 1 year
● Sick children
● Family planning
● Cd- TB
3. Tally reporting Forms- monthly report
"ILAN"
a. Hx programs
b. Morbidity report
4. Summary report: 12 columns
Events
E1- death and Birth
Quarterly report
Prepared by nurse submitted to the provincial health officer
Q1- 3 month program report
Q2- 3 month Morbidity report
Regional Health Office Regional health officer/ Quarterly report- every 2nd week of
FHSIS coordinator each second month
Annual report- every 2nd week of
March
Hospital based data of disease occurrences; It provides supplemental information for the
department of health
VITAL STATISTICS
Is the study of measure and proportions of quantitative data about the population
Health indicator of the births, mortality, mobidity
100,000-used in a greater population
100- percentage
1000-common
Formulas:
Group 1:
● Crude Birth Rate
● Crude Death Rate
Numerator- hinahanap
Morbidity
3. Data presentation=
● Descriptive= Narration
● Numerical = numbers, percentage, charts, figures
Examples:
4. Data analysis = standard/norm
5. Data utilization
PLANNING PHASE
Activity: prioritization
Criteria:
Family Criteria:
● Nature of the problem
● Modifiability of the problem
● Preventive potential
● Salience
Community criteria:
● Nature- What type of problem
● Modifiability- it has the most weight during prioritization*
● Magnitude- its the unique criterion in the community (population that is affected by
the problem)
● Prev. Potential- The potentiality of it to happen again
● Social concern/ Salience- Recognition of the problem
Family
Has *Not: starts with "0"
No *Not: "1"
Criteria Score Weight
1. Nature
Hx Deficit 3 1
Hx Threats 2
Foreseeable crisis 1
2. Modifiability
Easy 2 2
Intermediate 1
Not modifiable 0
3. Preventive potential
Highly 3 1
Moderate 2
Low 1
4. Salience
Need urgent attention 2 1
Do not need urgent attention 1
Not a felt problem 0
Community prioritization
1. Nature
Hx status 3 1
Hx resource 2
Hx related 1
2. Modifiability
Easily 3 4
Intermediate 2
Low 1
Not Modifiable 0
3. Magnitude
75- 100% 4 3
50-74% 3
25-49% 2
<25% 1
4. Preventive potential
Highly 3 1
Moderate 2
Low 1
5. Social Concern
Need urgent attention 2 1
Do not need urgent attention 1 1
Not a felt problem 0 1
Formula:
Score/highest score × weight
2. Set Goals
Types:
Short term: Attend to the immediate problem; Factors; specific
Ex. Water Sanitation, reflection of intervention (nurse)
3. PLAN
Evaluation parameters:
FNCP- Family Nursing Care Plan
CHP- Community Health Plan
Implementation/ Intervention
Plan- Action (Professional Stage)
Fxn of nurses:
● Independent Function- Chn
● Interdependent Function- Chn, Hospital
● Dependent Function- Hospital
EVALUATION
Types:
1. Qualitative-
2. Quantitative
Components of evaluation:
● Structure- input/resources
🚩
Parameters: adequacy, appropriateness
● Process- procedures performed
Parameters: efficiency, effectiveness
● Outcome- result
Parameters: met, unmet, partially met
DIAGNOSIS
Problem Identification
Prioritization
PLANNING
IMPLEMENTATION
EVALUATION
Principles of Copar:
P- people centered, participative, process oriented (client: poorest sectors) [oppressed,
depressed, underserved community]
D- democratic, developmental
C- change
S- Self reliance
COPAR team
1. proj. Director- Director of the school
2. Proj. Manager- Dean of the college
3. Coor. for immersion- RLE coordinator: Site selection
4. Hx service coor. - Clinical Instructor
5. Comm. Organizer- Students
6. Training officer- one who plans and implements training
7. Financial officer- Budgeting
8. Bookkeeper- Auditor; records all financial activities
9. Secretary- Documentation
_____
TAMA- RA 8423
Herbal Meds
Preparations:
● Decoction- boiling the plan material for 20 min.
● Poultice- pounding the plant- direct application
● Infusion- soaking plant in a hot water to release the extract for 10-15 min
● Juice/syrup- juice is more concentrated; juice with syrup (honey)
● Cream and ointment: + starch= cream : starch and oil= ointment
Alternative hx practice
1. Massage
2. Reflexology- (palms and sole)
3. Acupressure- ( acupoints- points of body meridian)
4. Acupuncture- (using fine thin needles)
5. Aroma therapy
6. Chiropractic-proper alignment of spine and pelvis
7. Reiki- power of palms- into the head or face
8. Pranic healing- (Prana- Aura)
9. Meditation- relaxation of mind
10. Yoga- relaxation if mind and body
11. Yin-Yang- promoting balance of bad and good
2. Entry phase
● Arrival & integration- 🚩
○ R- establish rapport
○ I- Imbibe community life
○ S- Share
○ E- experiences
○ R- respect culture
● Information dissemination
● Identify potential leaders
○ T- Time
🚩
○ O- Oriented for change
○ R- respected by the people
○ P- member of poorest sector
○ E- effective communication skills
● Core group formation
● Deepening social investigation- Primary Data is obtained
● SALT- self awareness and leadership training
7. Termination phase
● Self reliance
● Transfer of responsibility to the community
LOCAL HX SYSTEM
Inter Local Hx System- concept of district hx system
LGU- RA 7160 > Inter Local hx zone (Tool: LGU hx score card)
DEPARTMENT OF HEALTH
-Leading authority for health
Goals of DoH:
● Erap Estrada: HSRA (Health sector reform agenda) 1999-2004
● Gloria Arroyo: Fourmula one for health (F1) 2005-2010
Secretary: Francisco Duque III
● Elements:
1. Hx financing- foster investment for health– health is not a form of
expenditure
2. Hx service delivery- Accessible and Available
3. Hx regulation- Quality and Affordability
4. Good governance- improve Health Sectors
● PNoy- Universal Health Care (Kalusugang pangkalahatan)
Elements:
5. Human Resources for Health-
6. Health information
Philhealth benefits:
● Inpatient coverage- room, drugs/meds, Labs, OR, PF- confinement >24 hours
45 days of confinement per year - including the Dependents
DOH facilities:
Classifications of Hospitals of DOH
1. General hospital
2. Special hospital
Level 1-
a. Consulting specialist= med, OB, Pedia,Surgery
b. Emergency and OPD
c. Isolation Facility
d. Surgical and maternity facility
e. Dental facility
f. Laboratory
g. Pharmacy
Level 2-
A. Level 1
B. Departmentalized services
C. Respiratory unit
D. ICU
E. NICU
Level 3:
A. Level 1 and 2
B. Residency training for doctors
C. Rehabilitation unit
D. Ambulatory surgical unit
E. Dialysis
F. Blood bank
Category A- primary care facility (first contact health facility (Health center, Outpatient clinic,
Dental clinic, lying in clinic)
Category B- Custodial care facility (long term care) includes food and shelter
Ex: psych facility, rehab center, nsg homes
Phil adapted: oct. 19 1979, LOI 949 (Marcod Sr.) First country in southeast asia to adapt
Sectors:
Public- under gov.
Private- profitable
Levels of workers:
1.BHW/village/auxiliary workers
2. Intermediate level health workers (healthcare professionals)
I🩷
Pillars/cornerstone of PHC
USA
1. Intra & intersectoral linkages (Multisectoral)
2. Use of appropriate technology (herbal plants as a medicine)
3. Support mechanisms made available
4. Active community participation
RA 10152
● Other 6
● HEPA B
● Haemophilus influenzae Type B ( HiB) cause of infantile meningitis
● Mumps
● Rubella
2. Sanitation
Waste mgt RA 9003
Healthcare waste mgt, 2011 (DOH)
Black- General waste, non hazardous, non biodegradable
Yellow with ☣️
Green- non hazardous- biodegradable
- pathological waste and anatomical waste
Yellow with black band- pharma drugs, cytotoxic drugs, chemical waste
Yellow bag (autoclave)- infectious waste
Orange bin- Radioactive waste
_____int. standards
White- Sharps
Red- plastics
Blue- breakable
3. Essential drugs- BnB (RA 6675) generics act of the philippines
4. Emergency care- BEMONC (basic emergency obstetrics and Neonatal care) in RHU,
lying in or birthing home or stand alone facility
DOH- At Least 1RM or RN with a physician on call
WHO ratio:
1 bemonc facility: 125,000 population
6 functions (DoH):
1. Parenteral administration of oxytocin (3rd stage)
2. P admin. Of anticonvulsant
3. P. Admin of initial dose of antibiotics
4. Assisted delivery
5. Removal of retained products of conception
6. Manual removal of retained placenta
3 functions (newborn)
1. Newborn resuscitation
2. Treatment of Neonatal sepsis
3. Oxygen support to the Newborn
🚩
Prenatal care - HBMR (home based mothers record)- facility based record
Minimum visits- 4 visits
1st trimester= 1
to allow to deliver in lying in
2nd trimester- 2
3rd trimester- 3
8 mo. Onward - 4,5 of 2 weeks
6. Adequate food and proper nutrition (PD 491) nutrition act of the philippines
7. Local Endemic diseases
Ex. Malaria, dengue, leptospirosis
8. Health Education
9. Communicable Diseases (RA 11332) new!
Communicable Diseases- detectable alteration to normal tissue function
-With signs and symptoms
-Abnormal
Cell- Virus
Tissue- fungal,bacterial
Infectious disease- an infection that leads to a manifestation of signs and symptoms and
immune response
Contagious disease- Contact or exposure that lead to an infection and a disease (person to
person)
Or..
4. Opportunistic infection- ⬇️
defense system, immunocompromised
● MAC- Mycobacterium avium complex
- If immune is down can develop tuberculosis
● Mycobacterium Cansa. E and Avium - non tuberculotic bacteria
Concepts
Epidemiology- study of patterns and occurrences of the disease pattern (time, place, person)
-backbone of disease prevention
Spanish flu- Avian flu (ground zero is not identified) carrier (birds)
Ebola virus- Republic of congo in africa
Mers Cov- bats to camel (middle east)
HIV- chimpanzee (hunted for meat) infected blood SIV (simian immunodeficiency virus)
Patterns:
Chain of infection:
Rule: Break the chain of infection
Infectious agents:
1. Virus- smallest organism of them all, the most microscopic, intracellular organism
-Always needs a HOST CELL (that's why we isolate so that there will be no other host)
- not asexual,sexual
-self limiting
Replication: V. RNA infect human RNA = more viral rna
V.DNA combine to human DNA
may Transcribe to v. RNA infect human RNA
Dx: RT PCR( Rna), PCR (rna and dna)
Pharma: anti viral- (vir, vudine)
2. Bacteria- most common cause of fatal infectious disease (bacteria does not stop)
Bacterial spores- spore forming bacteria carries Toxins (Ex. DPT) (Anthrax= bacillus
anthracis> lighter than air, carries shiga toxin)
4. Parasite- invades
Protozoa- simplest single cell in the planet (plasmodia) plasmodium malariae- milder,
plasmodium falciparum- strongest (goes up to the brain)
Mode of transmission:
Contact: the most common mode of transmission
Direct- person to person (std)
Indirect- person to middle point (vehicles) to person
-Vehicle: food, water, fomites
-Vector: animal and insects
-Fecal oral route
Airborne transmission-
airborne (>3 feet)
droplet (within 3 feet)
aerosol- no nebulizer (use MDI metered dose Inhaler)
CA > Reservoir
● Cleaning
● Decontamination- specific pathogen
● Disinfectant- killing the microbes but not all and except spores
○ Germicidals/germicides
i. Antiseptics- skin
ii. Disinfectant- surface
● Sterilization- killing all forms of microbes
○ Autoclave - 121 degree CelsiuS for 30 minutes
○ Ethylene oxide- (1-6 hours)
○ Liquid chemical sterilants- requires longer exposure (3-12 hours)
○ Boiling
○ Radiation
Precautions:
Tier 1- standard precaution- priority
Tier 2- transmission precaution
Measures:
1. handwashing- the best and the most effective way of infection control
Who number 1 spreader- Healthcare workers
What is the number 1 spreader- Hands
Gown-
Double gowning- highly infectious patients
Mask-
Simple face mask
Surgical mask
FFP mask- filtering facepiece mask
Class:
FFP1 - 80 -94 % (KN94)
FFP2- 94-95 % (N95, P-2 mask)
FFP3- 99% (N99, EN1499, P-3 mask)
Donning- wearing
Doffing- removal
Tier 2-
Mode of transmission- same precaution
1. Contact precaution
Disease:
Respiratory Infection
Influenzae
Wound infection
enteric Infection- fecal oral (enteric precaution- more specific)
Skin infections (scabies)
Conjunctivitis
All Indirect contact (vector,vehicle)
Measures:
● private room
● Cohorting- placing the pt with another pt. (Place the pt with another pt with the same
infection status (mild to mild, severe to severe) exception: when there is an outbreak or
pandemic
● Gloves and gown (mask is optional if with respi problems)
2. Droplet precaution
1. Adenovirus- common flu (trangkaso)
2. Diphtheria
3. Influenzae
4. Meningitis
5. Mumps- infectious parotitis (Paramyxovirus)
6. Parvovirus B19- fifth disease (erythema infectiosum)
7. Pertussis
8. Pneumonia
9. Rubella
10. Streptococcal pharyngitis
Measures:
Private room
Cohorting
Surgical mask/medical grade mask (colored in)
Airborne precaution
-Measles
-Tuberculosis
-Varicella /herpes zoster painful shingles (peripheral nerves)
-Covid 19
Measures:
Private room: negative air pressure
Air exchange: 6 times per hour / every 10 min.
No Cohort: except pandemic or outbreak
Susceptible host
Primary line of defense- Skin, mucous
Secondary- inflammatory response
Tertiary- immune response
Mutation
2 types of mutation:
● Genetic- inward
● Antigenic- outward change (more deadly)
Antibody isotopes
Immunoglobulins
● IGg- Gama Immunoglobulin (most common type found in the blood) the only antibody
capable of crossing the placenta (Fetus) natural passive immunity (onsent- 21 days to
even years) (bacteria,fungal,viral)
● IGa- alpha immunoglobulin (seen in mucosal area,saliva, tears, breastmilk) natural
passive immunity
● IGm- Macro immunoglobulin (largest antibody among all) the first antibody to always
respond (onset- 5days or more)
● IgE- epsilon (responsds when there is allergy and parasitic infection)
● IgD- Delta immunoglobulin (antimicrobial- supportive)
Types of immunity: ⚠️
Natural- natural active (best immunity)
● Active- exposure and
● Passive-placental and breastmilk
Artificial- introduce/administration
● Active- vaccines and toxoids
● Passive-anti toxin, anti serum
Anti tetano- vaccine (address the bacteria itself) used for prevention [Artificial active]
T. Toxoid- weakened toxin (address the toxin) for prevention [artificial active]
TIG- antibody against the tetanus infection (for management) [artificial passive]
Vaccines
Types: artificial active
1. Live attenuated vaccine- actual infection (best vaccine) that provides long lasting
immunity (single dose)
-mimics The natural active immunity
2. Inactivated- weakened or a killed organism (not long lasting) multiple dose and requires
booster dose (most common in the world)
3. Active component- part or conjugate of the organism
- The most expensive
ex. hepatitis- active recombinant
4. Toxoid- weakened toxin (cannot prevent infection but it prevents the harmful effects of
the toxin)
ex: botulinum toxoid (botulism) bacteria > produces botulin toxin Cause muscle paralysis
(used in botox)
Covid 19 vaccine:
1. Live attenuated vaccine-
2. Inactivated- sinovac, sinopharma, bharat biotech (indian)
3. Active component-
mRNA- 94-100%
● pfizer- Comirnaty
● moderna-Spikevax
Viral vector-
Adenovirus- injected into it the vaccine for covid (Astrazeneca vaccine, sputnik V (first to
undergo clinical trial), Johnson and Johnson)
Program:
1st and 2nd dose- primary series (to achieve level of
Booster dose:
● Homologous- "same" to the primary series
● Heterologous- "different" vaccine
○ pfizer-store in 60 to 80 degrees
○ Moderna,
○ astrazenica
RA 10152
- 10 immunizable disease
- Hepa B- Pentavalent
- Hib- (number cause of infant bacterial meningitis) pentavalent
- Mumps- MMR
- Rubella- MMR (Mmrv new + varicella for chicken pox)
Principles of immunization
-1 needle, syringe, child
-All vaccine is sensitive to heat - requires a storage system
MOSTH- measles, opv, sensitive to heat
-freezer -25 to -15 degrees Celsius
LEAST- all except
-Body (+2-+8)
When exposed to heat- decreased potency
Technology: VVM (Vaccine vial monitoring)
Rule: the darker the vvm the more it was exposed to heat
Not give the vaccine- when the vvm has the same color from the outline
Cold chain- cold chain officer <maintains> (rho to provincial health office to municipal- rhu- bhs
and bhc)
Rule: rho, phd, mho (FDFD) first delivery, first to dispose
Rhu, Bhc (FEFO) first expiry, first out
Continue: malnutrition, anemia, cough and colds, fever <38.5, Diarrhea, (-)Western blot (HIV),
Missed dose:
Give the missed dose immediately and proceed with the interval
1- 6weeks
2- 4 weeks
3- 4 weeks
Others:
Influenza= flu vaccine, type: inactivated
● Cdc- yearly (as early as 6 months) .5ml
● Route: IM
● Brands: fluarix, flulaval, fluzone
Pneumococcal-
Types:
● PCV 13- 13 valent vaccine (given to child) pneumococcal conjugate vaccine 13 [prevnar
13]
● Type: Inactivated
● .5ml IM
● 1st dose: 2 mo, 2nd: 4mo, 3rd: 6mo, 4th: 12-15 mo
● Alert: needs to be completed before 2 years old
PPSV 23- 23 valent vaccine- pneumococcal polysaccharide vaccine 23 [pneumovax 23] for
adult
● 19 yo and above
● IM .5ml
● 1st dose: 19-64 yo; 2nd dose: 65 and above (singke dose)
● Interval: atleast 5 years apart
● If pcv 13 but not complete-
● 1st= pvc 13 = less that 19 years
● 2nd= ppsv 23= 19-64 yo
● Interval of 1st and 2nd is 8 weeks apart
● 3rd dose: ppsv 23= 19-64 yo
● 2nd and 3rd dose interval: 5 years apart
● 4th dose: final dose= ppsv =65 years and above
● 3rd and 4th interval: 5 years apart
Tips:
Inactivated- common type
Route: IM
Dose: .5ml
Schedule: 644 mo
Side effect: fever (2-3 days only) if more than this in not assoc to the vaccine except measle
vaccine: fever can last up to 7 days
Side effects: if what vaccine side effects will be the same but milder
Extra PTB- tuberculosis outside of the lungs (common in child and immunocompromised)
Site: common in the organs close to the lungs: bone, GI, GU, pleura, lymphatic sys., may
develop TB meningitis (common to pt. have chronic TB)
Mycobacterium-aerobic (aerobic) > inhale> pulmonary alveoli > signs and symptoms > lung
tissue > replicate > fibrosis of the lung tissue> parenchymal lesions called (lung opacities) in the
Xray
Diagnostic test:
Primary: screening
● Mantoux test /tuberculin test/ Ppd (ID .1ml site: lower inner aspect
● result (48-72 hours)
● False positive: BCG
● > 5mm- positive
● >10 mm- postive to heathcare, children <4yo, prisoners, travelers
● >15mm - general population
Igra Test- interferon gama release assay / TB gold / quantiferon tb test (uses blood) (not
sensitive to BCG)
Treatment: HRZES
H-isoniazid (INH drug class)
● S/e: neurotoxic (isip)
Rifampicin
● Red-orange body secretions
Z-pyrazinamide
● Hepatotoxic
Ethambutol (only bacteriostatic)
● Eyes (optic neuritis)
Streptomycin
● Ototoxic, nephrotoxic
Leprosy
-"Lepos" skin
-Leperos (the scaly man)
Other names: Hansen's disease; Hansenosis; the lepers disease
Pathognomonic sign: Lionin' face /leontiasis
Leprosy attacks the skin
Leontiasis ossea- the bone is involved
Paget's disease- there is completely bond remodeling
Causative agent: myco. Leprae (loves cold environment)- it has lower body temperature
Reservoir - Armadillos
Mot: direct contact (droplet) requires prolonged contact with an untreated person with leprosy
Incubation: 9mo-20 years; cdc: 5 years
Pathog: cutaneous skin lesions, neuropathies (hands and toes), sensory loss in the limbs
Who Classifications:
1. Paucibacillary- low quantity ( tubercular type) 5 or fewer skin (2-5) lessions
a. Single paucibacillary- 1 skin lesion
2. Multibacillary- lepromatous type, 6 or more lesions
Patho:
M leprae> replicate in cooler temperature > enters through droplet > skin [s/s: skin nodules, skin
lesions (non healing lesions), loss of sensation of the areas of lesions, anhidrosis (inability to
produce sweat), dry skin, loss of hair (eyebrows, eyelash), lesions turn to plaques and has
enlarged nodules in the earlobes, nose, eyebrows,forehead
Peripheral nerves [s/s: nerve damage> atrophy of hands and toes, claw hand, claw toes, foot
drop] [ muscle weakness, paresthesia, ] [facial nerve paralysis> Lagophthalmos (inability to
close the eyelids completely)> corneal ulceration > scaring > blindness]
[Respiratory mucosa, upper respi > nasa perforation, saddle nose (collapse of nasal bridge),
epistaxis, ulceration in the uvula and tonsils,]
Diagnostic test":
Confirmatory:skin/biopsy disease (cdc)
Skin smear/ skin slit smear -who
Method:tiny skin sample of tissue (8mm in size) microscopy staining = 1% acid alcohol or 5%
sulfuric acid > 100 fields
Site for sample: tissue of the active lesions
Prevention: BCG
Treatment: multi drug therapy
Who tx protocol:
● Paucibacillary- negative skin smear
○ Rifampicin (600 mg/once a month)
○ Dapsone (100mg/ od)
○ Treatment course: 6 mo.
○ Acquired in who (blister pack) 6 blister packs
● Multibacillary- positive skin Smear
○ Rifampicin (600 mg/once a month)
○ Clofazimine (300 mg once a month) 50 mg od.
○ Dapsone (100mg/ od)
○ Tx course: 12 months
○ Day 1= R,C 300, D
○ Day 2-28= C 50, D
○ 12 blister backs
● Single lesion= single dose : rifampicin 600 mg, ofloxacin 400mg, minocycline 100mg
Stages of Pertussis:
1. Catarrhal/prodromal- 7-10 days, mild cough, low grade fever
2. Paroxysmal- episodic attacks (usually at night) whooping cough for 1-6 weeks - 10
weeks (maximum 70 days)
3. Convalescent stage = gradual recovery 7-10 days max. 21days
Tetanus
Other names: lockjaw, sardonic smile disease, trismus
Ca: clostridium tetani (anaerobic bacteria) can be seen in soil, manure
Produce a toxin called tetanospasmin cause muscle spasm
Mot: direct contact /indirect (spore enters to the wound/skin abrasion)
Incubation: 3-21 days, ave. 10 days
Pathognomonic: lockjaw/trismus, sardonic smile (risus sardonicus), opisthotonus
Patho:
C. Tetani> enters the wound > release toxin - tetanospasmin > affects neuromuscular fuction>
spasm start on the face [trismus and sardonic smile] > descending pattern spread >
opisthotonus > muscle tearing/bone fracture
Types of tetanus:
1. Generalized tetanus- most common form of tetanus, triad sign, 10-20% mortality
2. Localized tetanus- mild form, happens in partially immunized pt, low mortality
3. Neonatal tetanus - highest mortality, site: umbilicus, poor feeding, can lead to full blown
tetanus
4. Cephalic tetanus- rarest form, incubation period: 1-2 days, a result of head or neck i
jury, unilateral face palsy
Dgx: Clinical presentation, spatula test (touch posterior pharyngeal wall) gag- (-), spasm (+)
Vax: pentavalent
Tx: Antibiotics (penicillin), TIG (IM) 500 IU single dose, muscle relaxant (benzodiazepine) pain
meds, intubate if laryngo spasm,
Complication:
Fractures
Meningitis: Alert ⚠️
- Inflammation of meninges (membrane that is covering the brain and spine)
- Leptomeninges (2 layers of meningitis) arachnoid and pia
Fungi: cryptococcus
Parasite: plasmodium
falciparum (can cause
cerebral malaria)
Hematogenous spread:
(Meningococcemia)
Photophobia
Phonophobia
Meningoencephalitis> altered
mental thought process,
seizure
Bacterial meningitis:
isolate: 24 hrs from the start
of the treatment
Treatment:
● corticosteroids( 1st to
give to prevent further
inflammation)
● antibiotics (2nd)-
broad spectrum
(cephalosporins) doc
for meningococcal
disease
INFLUENZA
Other name: The Flu
CA: Influenza virus
Type: A- HN (affects both humans and animals) , B- seasonal flu ( yamagata and victoria
lineage) humans only, C- mild flu, children, D- animals only ex. Cattles
MOT: droplet, fomites
Incubation period: 1-4 days average of 2 days (compared to Omicron)
Pathophysiology:
Type A- causes outbreak
H N- surface proteins,
H(hemagglutinin)- used to enter, attach (18 kinds)
N(neuraminidase)- use to exit (11 kinds)
Site: upper respi > bind to endothelial cell> H protein> release viral protein>replicate> bud/exit (
N protein) > new virus > infect other endothelial cells
Mumps
Other name: infectious parotitis
CA: mumps virus, paramyxovirus (target: glands of the body)
MOT: droplet
Incubation: 12- 25 days (ave. 16-18 days)
Pathognomonic: painful swelling of one or both parotid glands
Pathophysiology: mumps virus> droplet >1st gland exposed (salivary glands)
> parotid >parotitis> common: bilateral> s/s: low grade fever, headache,
malaise
Complications if not controlled: Orchitis (testicular gland), Oophoritis ( ovarian gland), mastitis
(mammary gland)
Diagnosis: clinical presentation
Vaccine: MMRV Proquad- 2005
- Droplet precaution
—-----
Viral exanthem- Rash disease
-Outside
Enanthem- internal (first to show before going outside)
Diagnostic of both: PCR, elevated, IgM and IgG (if Igm first- german measle; if both elevated-
measles
Vaccine: MMRV (quadrivalent)
Treatment: Symptomatic, antiviral (isoprinosine) (for measles)
______
Chicken pox - highly contagious
Other names: varicella, child pox, itching pox
CA: varicella Virus
MOT: Airborne, fomites
Incubation: 10-21 days; ave. 14-16
Manifestation: Rash
- Centripetal Rash- inward (more in the Trunk)
- Highly pruritic rash (Macule- there is change in color)
- Papule- <1cm
- Vesicle- fluid filled
- Pustule- pus filled
- Crusting-
-
- Diagnostic: PCr
Childhood Adulthood
Chickenpox Smallpox
Fever appears at the time of the rash Fever for 2-4 days> Rash
Centripetal Centrifugal
Inward Outward
More: trunk More: extrem.
Less: extremities Less: trunk
________
VIRAL HEPATITIS
Came from the word: Hepar= liver (one of the largest part of the body)
Itis- inflammation
Causes:
1. drugs or meds
2. Excessive alcohol
3. Infection- virus (hepatitis virus)
4. Hepatitis X- hepatitis from an unknown cause
Liver fxn:
1. Bile production
2. Bilirubin - brown (clay colored stool if affected ang liver)
3. Blood clot- Vit. K - Bile is essential for the vit. K to be absorbed
4. Carbohydrates
5. Vitamins & mineral storage- ADEK & B12
6. breakdown of proteins
7. Filters blood
Hepatitis A
Other names- infectious hepatitis (Catarrhal jaundice)
Infection: acute- <6mo.
Ca: HEP. A VIRUS- SS Rna
Mot: fecal oral
Incubation: 15-50 days ave. 28 days
Dgx: increase ALT & AST
IGM- inc. Acute infxn
IgG- inc. Convalescent
Treatment: supportive, Bed rest
Vaccine: H.A Vax
Contact precaution / enteric precaution
Proper waste management
Hepatitis B
Other name: serum hepatitis
Infection: acute and leads to chronic
CA; Hep. B Virus (double strand DNA)
Mot: blood, sex, perinatal
Incubation: 60-150 days ave. 90 days
Dgx: lab- specific serum markers
1. HBsAg- hep. B surface antigen - first serum marker to appear ( peaks at 12 weeks) (and
undetectable after 6 mo.
- Can also be used to confirm immunity- Heb. b vaccine ( ) ⬇️
2. HBeAg- hepa. E ANTIGEN
- Viral Replication
- 6-14 weeks
- Vload- ⬆️
HBeAg
- Placental cross
PCR- quantitative
- Viral count
Treatment-
chronic- Pegasys- pegylated interferon
Antivirals- lamivudine, entecavir, tenofovir (either)
Hepatitis C
Other names: Non A, Non B Hepatitis, inoculation hepatitis
Infection- acute > chronic
Ca: Hep. C virus (single strand RNA)
Mot: sex, blood, perinatal
Incubation: 14-180 days (ave. 45 day)
Treatment: pegasys
Vaccine: hep B vaccine
Precaution: blood borne prec.
Hepatitis E
Other Name: perinatal hepatitis
At risk > pregnant women
Infection- acute <6mo.
CA: Hep. E virus - SS rna
Mot: fecal oral
Ip: 15-60 days (ave. 40 days)
Dgx- pcr
Tx: ribavirin
Prec. Contact prec/ enteric prec.
Health teaching- proper waste mgt.
Complication: fulminant liver failure (too much hepatocytes died)
Pathophysiology of hepatitis:
Release ss rna + rna = more viral rna > replication/ release > exit> invading other hepatocytes>
cell lysis> apoptosis> necrosis> deterioration of liver fxn
Hep B> release DS DNA> + dna = more viral dna > other will transcribe= viral RNA (will go to
RNA)
Stages of Hepatitis
Prodromal- viremia -virus in the blood, fever, headache, fatigue
Icteric- liver damage, jaundice, urine is tea colored, gray or clay stool, yellowish sclera,
hepatomegaly
Convalescent- liver returns to normal size, improved appetite, jaundice decrease, stool and
urine is going back to normal color
_______
Zoonotic Disease - non human animals to humans
Reverse zoonosis
Leptospirosis-
Lepto-thin
Spira-coiled
Spiral aerobic bacteria
Other names: weil's disease ( if sever leptospirosis), canincola fever, Hemorrhagic jaundice, the
japanese 7 day fever, mud fever
CA: Leptospira specie, most common: L. Interrogans
Reservoir: rodents, small mammals, domestic animals
Mot:
1. Direct contact with urine or reproductive fluids from infected animals
2. Contact with urine contaminated water (Flood, streams, sewage, wet soil,) wound, skin
abrasions
3. Rare- ingestion of food and water contaminated by urine or urine contaminated water
Pathophysiology:
Leptospira(aerobic)> mot: skin breaks/ wounds> bloodstream (multiply)> organs (kidneys, liver,
brain heart, lungs)
______
RABIES
Other Names: hydrophobia, lyssa, mad dog disease
Ca: rhabdovirus/lyssavirus > neurotropic virus - target nerve cells, sensitive to light and
hydrophobic
Mot: contact saliva- biting behaviour, scratching or licking
Reservoir: Dogs- Ph, bats, Raccoons, skunks, foxes
IP: 1-3 months can be up to 15 years
Depends on the ff:
● the distance of the bite to the brain
● The expensiveness of the bite
● Animal specie
● Nerve supply in the area of the bite
Manifestation:
3 phases:
1. Prodromal - invasion phase
● Fever,anorexia, malaise, sore throat, nausea and vomiting, copious salivation,
lacrimation,perspiration, restless and irritable, pain at the site of the bite,
sensitivity- light,sound, temp
2. Neurologic- furious or excitement phase
● Excitation and apprehension> fear
● Delirium with nuchal rigidity and invol. Twitching
● Maniacal behavior= eyes are fixed and glossy skin is cold and clammy
● Profuse drooling
● Aerophobic
● Severe and painful spasm = month,pharynx, larynx= attempt to
● Death= spasm > respi & cardiac failure
3. Paralytic phase- terminal
○ quiet and unconscious
○ Loss of bowel and urinary control
○ Progressive paralysis
○ Death- respi paralysis, heart collapse
Pathophysiology:
PVRV:
Who tx protocol: ⚠️
Category 1 - feeding, touching an animal , licking- intact skin, casual contact with rabies pt.
Action: wash with soap and water, no vaccine or RIG needle
Category 3- single or multiple transdermal bites, broken skin with saliva from animal licks,
exposure or direct contact with bats
Action: wash the wound with soap and water, start and complete the rabies vaccine and RIG
Nsg. Management:
1. Isolate the pt.- contact precaution
2. Comfort > hyperactive episodes
3. Provide a quiet and darken room
4. Pt should not be bathed. Shouldnt be running water with hearing distance
5. IV- wrap
6. Disinfection
MOSQUITO-BORNE
Characteristics: Black and Dark legs, dark thorax, dark Tan colored thorax, striped
White striped legs, lyre wings dark legs, dark wings
shaped thorax
Dengue
Other names: dengue hemo fever, breakbone fever, dandy fever, infectious thrombocytopenic
purpura
CA: flavivirus- RNA virus
4 types:
1. DENV 1
2. DENV 2
3. DENV 3
4. DENV 4
5. DENV 5
Vector: (female aedes mosquito)
● Aedes aegypti- the yellow fever mosquito, tiger mosquito
- Before sunset, dawn
- After sunrise- indoor
Pathophysiology:
Diagnostic: rumpel leads test- screening
Dengue rapid test- IgM and IgG
Vaccine: Dengvaxia- 2019 revoked license
Prevention and mgt:
Low fat, low fiber, non spicy, non carbonated
Analgesic
Monitor for signs and symptoms of shock and Hemorrhage
ORS (NP1) IV (other NPs)
Malaria
Other names:
● marsh/jungle fever (common in forest)
● Ague
● Periodic fever (Paroxysmal- episodic)
● Swamp fever (palawan, mindoro, rizal province)
Ca: plasmodium- tropical protozoa
Types:
● P. Falciparum- most common in ph and the most deadly of all (considered as a
malignant tertian
● P. Vivax- second most common (tertian malaria)
● P.ovale- tertian malaria
● P. Malariae- quartan malaria (rare) mildest
● P. Knowlesi- monkeys in SE asia
Pathophysiology:
Cdc/who:
Atovaquone- proquanil
Doxycycline
Mefloquine
Mgt: CLEAN (same with dengue)
DOC: "arte" "quine"
Artemether-
Artesunate
For pregnant:
If falciparum - quinine
If vivax- chloroquine
Zika fever
Other names: zika virus disease
CA: zika virus
Vector: aedes aegypti, A albopictus
IP: 3-12 days
Mot: Vector borne
The only mosquito disease that is transmitted sexually-anal, vaginal , oral, sex toys
-it can live in the semen up to 6 months and in vaginal fluids with atleast min. Of 8 weeks
-Can be transmitted via blood transfusion, perinatal transmission
Signs/symp: commonly asymptomatic (80%)
If symptomatic: last for 3-7 days
Low grade fever
Arthralgia
Conjunctivitis
Rash (maculopapular rash) pruritic rash (makati)
Diagnosis: Zika virus RNA NAT - nucleic acid amplification test (CONFIRMATORY TEST OF
ZIKA)
Sample: urine, serum
- IgM serology test
Prevention: safe sex (condom) for 6 months
Abstinence
Treatment: supportive care
No nsaids- not unless dengue is ruled out
Syphilis no. 1
Gonorrhea- highest
Herpes simplex- viral in ph
HIV/AIDS
Types of HIV:
HIV 1- common world wide; a stronger, more virulent strain
● Group M- more common - 90 percent cases
● Group O
HIV 2- largely confined- west africa and southern asia
- Rare,weaker, less virulent strain
- Pt will likely die with HIV 2 because HIV 1 has more treatment and HIV 2 has less of it
and few
MOT: Blood, Semen, pre- seminal fluid, vaginal fluids, rectal fluids, breast milk
Incidence rate: 84 percent, male to male sex; 11 percent male to female sex; 4 percent sharing
of infected needles, 1% is vertical transmission, blood transfusion
- This two will lead to the decrease of the CD4 cell count (Helper T cells that helps
infection in the body)
- Will lead to higher risk for infection
- <200 cd4 cells ( immuneless state)AIDS + Opportunistic infection can only be
classified as aids if both is present
- 0 cd4 > leads to opportunity infections ( infections that affect multi organs of the body
which causes death of HIV)
Stages of HIV
stage 1-
1A- primary infection- Acute HIV Syndrome
-2-4 weeks last to 1-3 weeks
-CD4 lower than the normal (<1500 cells/ml) gradual decrease
S/S: flu like symptoms, night sweats, fatigue, headache, persistent generalized
lymphadenopathy
Stage 3- AIDS
- Cd4 200 cells/mL + Opportunistic infxn present
Opportunistic Infections:
Any CD4 count:
● TB
● Oral Candidiasis- 200-500 cd4 (tx: oral fluconazole)
● Kaposi Sarcoma- an Aids defining illness (more common with cd4 count below 250)
caused by Human herpesvirus 8 HHV8 ( red, purple, brown or black papular lesions on
the skin)
CD4 <=250:
● Coccidioidomycosis- Tx (fluconazole oral until >250 cd4 count
CD4 <200
● Bacterial pneumonia- tx PPSV 23 (pneumovax) polysaccharide pneumococcal vaccine
(Given every 5 years)
● Pneumocystis pneumonia- CA: pneumocystis Jiroveci (fungal infx)
- treatment: trimethoprim, sulfamethoxazole (cotrimoxazole)
3. Isosporiasis/cystoisosporiasis
- Watery, non bleeding, diarrheal disease
- Protozoa- CA: cystoisospora belli (tx: cotrimoxazole)
4. <=150
● Histoplasmosis- tx: Itraconazole, amphotericin- B
5. <or= 100
● Esophageal Candidiasis- s/s: odynophagia (painful swallowing) manifested by
retrosternal chest pain
- treatment: fluconazole or itraconazole