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  • 乳腺癌术后高危人群复发转移影响因素及中医治疗评价 富琦)

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    乳腺癌术后高危人群复发转移影响因素及中医治疗评价_富琦)

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    11 views5 pages

    乳腺癌术后高危人群复发转移影响因素及中医治疗评价 富琦)

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    2014 2% 21 AH 2H 27 FLURIEAS I BIE A TESS BG SB BA BS BP BRIT EST HH, Lok, HE, BAR PF ABBE CSB RAG PERL BERT, LHC 100010 WEAN ALAR SRAAMLANGOMWAL, HO MP RAMEE TET, MRL KAEBE OA Aelh. PE ITS (LACE IRR ILARST AS B A SER A AEAB Rt RRA DAT, HRP KSA CP AEE +A Dai) SO RAF CN PEE) LRA, Lak AA aA PBR OMEGA, PAT, LERLP RMLGT I PORTRERGRARRH AREER AU, RERMP HR HABL AMMA RS AE. HO RAIA, PRIA 3 FRA. BAS, RAHA EEL (P=0.08) 5 MOAI PD IR AR EARP GBT 8 AN ALO AOSD PR, KPMG OMA BARE LPR STAT OMG SAAT HOT ER, GT RAR RAZ, DFOSAMREAMREMAAE HE TOUGH OM, AGATE RMB ABIL RG SAE 2 SLE MPL IT TAR 9 EE, LAP REAR, IRAE SI RS HAH SFA SORT GURBR SG: AAR: AU: Home: Po DOI: 10, 3969//j. issn, 1005-5304. 2014. 02. 008 SESS: KOT. 19 SREATIRNB: A SERBS: 1005-5804 (2014) 02-0027-05, Influencing Factors of Recurrence and Metastasis for Postoperative Breast Cancer High-risk Population and Evaluation on TCM Therapy FU Qi, SHI Lin, YANG Guo-wang. WANG Xiao-min (Oncology Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University; Beying 100010, China) Abstract: Objective To observe the influencing factors of recurrence and metastasis for postoperative breast cancer high-risk population, and TCM regimen of syndrome differentiation and treatment was used to validate its significance for the prevention of recurrence and metastasis. Methods The influencing factors of recurrence and metastasis of 178 postoperative breast cancer high-risk cases with positive hormone receptor were studied. The recurrence and metastasis, disease-free survival and accumulative points of TCM symptoms of integrated group (with TCM syndrome differentiation and endocrine therapy) and western medicine group (with endocrine therapy} ‘were compared. Results Lymph node metastasis, cancer staging and TCM therapy had influence on the disease-free survival rate of postoperative breast cancer high-risk patients. TCM therapy was the independent prognostic factor for disease-free survival. 3-year recurrence and metastasis rate was lower in integrated group than that in western medicine group, with statistical difference (P=0.03), ‘The total accumulative points of TCM symptoms in both two groups decreased after treated for 3 and 6 months, integrated group showed greater significance. TCM therapy was better for the treatment of irritability, hot flash and perspiration, good for spontaneous perspiration and insomnia, but poor in dry mouth, bitter taste in mouth and fatigue. Conclusion Lymph node metastasis, cancer staging and ‘TCM therapy are main influencing factors for recurrence and metastasis, TCM therapy with regimen AIMED, sem AHF x18 2 (Z09050700620907) SEWER: 2S A, E-mail: nt 000sina. com Chinese Journal of Information on TOM Feb. 2014 Vol. 21 No.2 of syndrome differentiation and treatment can reduce 3-year recurrence and metastasis rate, improve ‘TCM symptoms, especially is significant for the improvement of irritability, hot flash and perspiration. Key words: postoperative breast cancer: high-risk population; recurrence and metastasis: influencing factors; traditional Chinese medicine therapy FURR AY EE A HE RR HT Eb, (8 AIG TRAE ER BL 5 ARCA CAR ERE, BE i, ESE BASH AS ES EB A UPL PCS REE AE. AGE ILPHT 178 LAL, RAR HAE EO, FP OL BEPRIEP REIT ROR, BIE a FS 1 PRESS 11 aE ‘LAG 2009 481 HL E2013 4 1431 PO AAA PRI BBR Be. EAE AP A Bear Bie. PRP BSED eS Bie A ECC 307 PR BAMAA See (EeHt AY a~Lle AL REA ae, HMB, 38 AA 200 Gl, BS 2013 4 4 ABBE A 6 VUE FBR AC CLS ELBE 4 4S, SRE R IM ELAR 1~3 MALY PALA AAD er-2 GAME), Ese A a RAE HEBD EEN, ESLER ARERR ABE, BRANT, STALE. 1.3 AER Act tribals, PS PPA REA, REE MTL a AR aE 1.4 hi Af HSS BLES 1999 4 CRE A LRAT SLT LB YD; THM SBS MSA (ACC BEANE CRARO Ds PEEBHE REI coh 2 a AGUA TTA I CRT) OB ARDEBEGLEL 2009 SE-FLMRMIh BESTT MEAG. 2 WK 21 Kabra RLS le, AMGEN UAE FESR, MEET A Sea FA Ba AL HH IE HERAT, MERA RAEN RE. AEF 200 il. AEB ATT SAA. DEBE DA RS SGA) PT BREIL: PRB UEIC IA IA SPT. PBS BBIE ENF: SABIE FOU FIR, sR EI i He HOR, DRE EA Aaa, Bae HE A A He, ronic Publishing House iE FAR IEE OR, BALE TAR ae, EFORCE A SESH ies LOL. EE I, aA. SII. BGG. AEE, bites, Rb). HORST RALEIGH A RMEAT LS 2 4, 4 FLUE EAL Ry ST RUB LAR PDE CTT ‘EES TRAE A NA. Duryea Feb. QUART, MRAP LT TAK. 2.2 MAR 2.2.1 SAE AMIE 1 MITER. OF RA: HART HL EE Ae (CRED ERAS. OH eR: OWRENE: CT WRI, BALL KAR, PHI 2.2.2 RE AA A 2 ARES APB 1%, 2 SPEND Lk. HATE: SUKRODTRMICTE SRT. URE, Ya), ALM. HEY Bee LAMA, AAT RARE. BEM AR PORTER EUS. (AMER, BASE, MURR. BCT. Bal, X PHAR REIEIRI A 3~6: PAL the 2.2.3 MLR AEALE DUR e BLS REA es WURDE ats ALi PURI, wee Bika SEs ET 224 BAR AMIR EH REE ‘iLL IT EG EA I EL 2 BR Asie Be. 2.3 aR EAE SETAE anh aie el i: UREA, FETS. 2.3.2 RESTA ROEM SRRDLEDT Tee 8 CA EIA LP RR PEER, OHNE A. DANE ERT. tk ie. IAAT. NNT. OS. EOE ALONE BATFE, JRE. EREKIN (iR URE. RERARK. (LAER, HUME AREAL, HR Goh SL RTCA SHIM RAT) "SATE 1~3 She 24 ite Rll SPSS19. 0 FREbACARUEAT SHH. REA AEAE EAALIE OR: DIR. HE 212 SERGE 2014 #2 A 21 EH 2H THEA, Fr FETE REAR LCORL Kaplan-Meier SAUTE APA, Log rank REORMETADT EG: WAT MT AE TR, MAR PL LESTE PRAIRCAT ¢ RON, MARAE ELIE AS RA FRI LCRA. RF PROTA] BB BRIT RCE PSEC, FALE ASP AE ACA AS RO, AB PSEA TEAS 99 AU RFA PE AA A 6 BK PSS RH BT BOR BFR. P< 0,05 RA HAR ER Re 3 aR 31 aba FEA 200 PR, BRE 22 HH, FERRET BIE 178. Pile SPA DUBREG EEA SI 91 fl, PUBREA SI 87 fl. tf He 31~75 BRL 1~3 9 18 AO A 74 fal, >9 6 56 fil: MEDS IL 44 fal, Ila $4) 78 4, LIT, Ue 3) 56 fil; Bee 4 LIF 32. (Pl, 6 FOMMLAT 70 fil, 8 WIEST 76 il. See He HL, PAD UER, Re Re, NET. e EAC PIAL, FETE AGEL FR X (PHO. 05) « 3.2 Sem FUMR AR AG wh A AAA OL AY 178 fA RR ACs fe BARAT Kplan-Meier ‘EAeSb Bis TY DPS Wy (29. 81412. 97) 1, BLK 48.0 ANA, BERL 3.0 7/9, "Pie DPS 99 28.5 SA. 1, 2, 3. APART Teme AEK ADs 97. 68 (162/166) . 94. 6% (122/130). 92. 0% (69/75) « 3.2.1 RELL AE PRR eae ame AEA, SERBIA, DRA HRSA GA CLND CREAR ACE. FURR ACE. Her-2 SED RI AACE. AAR, HoT LM, EO SeRIUPLIATT ETMR LEBEN BUT BR SIR AD, SR, AR AS BA AeAEASRC ODL Eh, LM, MRIS. ETRE iE 9 MBL LAR Aiton, BARI (P-<0. 05). Sef LNMS3. AME Rit Fa EEF LN 9 MEE P= 0006) = FET I LEE 50058 rh iE EFL Mle BA (P=0. 009) « HEADS BERT AMR AA SEE A FEN EE EAE A HE (P>0. 05) « 3.2.2 SERRE RAL Enter 3 Cox KAA BO BUN MET & BURL THT, SH AU SHITE RE PO, 05 AIR, AV LNM, DAMEESR. AS HRAD 2G. SRSA, FE Ea A 2 A PS HAA ABR. SAE Le -2022 China Academic Journal Electronic Publishing Hi 29 RL OS SERRE We Pie owt $64 wo 0.401 tt 0.410~6.408 Memene 0.085 16 0.216~5.515, ammnne oon 2.687 1.090~6.4 323 BERTI AVR ib Ha Ae SECA CE EAT ER, HARE LN METALL ART. HE LNW ESB HAO FL O 43 3, EAP I Ua HA LIb~LlLe SUF, ZEAE PADI SUH DFS UL SGEAT Log-ranke RS. LNW A~9 ASI, PREGA DES He FRED BU (P<0. 05); SHEAR <3 FR>O itt, IBA DPS 225R 4 S(P>0.05) « “SI ANAM PEAS EEDA DPS He FPR BA SI (<0, 05): YUH 59079 LIZA ~ Le SO, BAR DPS SRSA X(P>0, 05). TH 2. 2_RPRWEA FPHIADIOS HAR Hb FD) wo PRISER PIO. OD _ BEER ON) nw no 0 wor mao ako >a 2a 2.0 wae WM 0 0 ta a m0 240 its 265 ma He SHR 3.3 PLAS A AOFM it Aa AR AR PHRASE DES 3y (29. 96+ 12. 49) A, Hei DPS Jy 29 4A: UBB) DPS 9 (29. 66 13, 52), “Pit DPS 9 28 4. PRIMAL DPS ELAR IE SE KA EEL (P=0. 267). PRA SII 1, 2. 3. SERA EER HY 96, 6%, 95, 3%, 93. 7%, PHBE BAP 1, 2, 3 ABR ET TCA EAE BL 94. 2h, 88, OH 85. 1%. 22 Log-rank #42, 2H PABMS 1, 2. 3 ER TE REIIE AR EOE RAEI (P=0. 043) « 3.4 OLR RHA EDEL MT I, SRP BASE 23 fl, AE BH 25. he HEP DUE EBT 7 (7. 7), PHBE BASIL 16 (C18. 4%); ARS 3 EAE TE 6 Oa, HC Peep DOLE ABA) 1 PCL. 18), DUEEBK SIL 5 (6. 41) . LEITH, SG PUBRIA SULA, OME OAS 8 SEA PEE AT LEG, EAT RUPE X (P=0. 03). BASSET AR ECR, 22 RAE PREM (P=0. 193) » 35 eT ATS PLP Dis Rae Re AE 3.5.1 PEARS AT Nhe AML INIA), 178 PAR se Mise REMY 3 A 6 A BUS ER AE RCA 156 Hl, Teepe PRES ABI FAL 84 (, PHBA 72 fo. Bae HA BRI SARA, Zo ARAL: HNRZ AF 59.0%, AIP 59.0% ARVFHL 96. 4%, SEER 55. 8%, FIFPID8F 53. 84, LIL} 50. 6, BEREAN 42. 9%, PAK AUEE 40. 48, FRAN 1H 35.9%, POURS 83. 98, LEHI 22. 18, lok (hh 92.1%, FESR 92. 1%, FCT# 28, 8%, HOBIE HH 28. 2%, (EAB 25. 6%, (EB 20. 5, 35.2 AFLG HERRERA RRR HR DIAL a AAO HY HEAR BL SP AE RRER, TAPAS RUTH. BERGA, PUB A ABA) APF BG SHINER LSP HIB SE “2G (P=0, 00): 5 3 AINE ARG, 97 6 4 IN EARS BUS OS BE, ESSE ih KX (P=0, 00). 4 DS 2s A Bi ARR ok PEAR A, BA Te FS WAL, BRA RUE RO OD. HF 3 TAB, SPEDE Bi Ea BA UTE AR ATS (7, 94-4 4, 87) Sh UPR DAS Ay (6. 94-45, 40) 5h, ERAT (P= 0.227). AT 6 SAR, DURE EBA SUREAR RY JY (6, 024, 50) SP, PUI DA SI (5. 535, 57) 54, = BE RARIPE RM (P=0. 19)» 3.5.3 FRU PAT WB LSE RP RR RAY SOME FLA AR sf, ABP AE UL BT. BPH. ORE. OPO, Ii gin Tor SEE. RADARSAT SEIT AAT. WEB, #40 25S PRINT eh a RIED MAC ARH ON) Re oe aS Ese YE oe HD ER Ee AH ao ween NR 2s APH T 7 1 1 TE ae or soo TBR 6 5 a o ee 2 4 8 Pa " a 1 a) By 5 w A a 3 2 FOE APR we wow Pa 2 2 2 OES AFR a 7 a Age 5 2 3 1 Yes 9P<0.05, FRR RAE He 3 BD, SSE ASPEERS, "POBE SE ABA WT 8FARO NAB, HORE A (P=0.01), LIE China Academie Journal Electronic Publishing Chinese Journal of Information on TOM Feb. 2014 Vol.21 No.2 + RER(P=0.0D, 00) 6 NE FEAR ee ayaa ERAGE. GHMAE Hee, DER BA WIT 3 Nis, MARZ 7 (P=0. 00) , FIFF(P=0.01) HP Ha (PO. 0138 3 MAE TEAR iv ssa, RORIPUL ORES CAIUS 3 NEI itr 6 OA, 10) RAR P= 101) ik 51h LAER URL A ARE Ak Pee, AAT a RD A EE RE SEE 24 RIAA MIADISTENIRILARU) wi 1 EH HRIRIEEOL—son.0 5.8 seca sesr.0 10.5 et MERE EAA Toa. as BEB 4615.5 90.5 mah UE SO)— t0.s save. eee 4018.5 ra18.5 ‘kW SOUBEREELAD TOMO arra BER 5022.0 08.0 CPOE eMEEREEOLA owe. 0 8.5 BEA siwa.0 8 LARA ROUSSEL Tao" 8.5 BEB 3961.0 50.5, es P=0.05 HE 4 FTA, DURES URE Ey. RHR FONG SAF EAR ARE OP BAD He PA, Bi, HARPER (P>0. 05) s MELE BUTE. SCALES 3 ANH LTEAR I RAR ACT SY PH BEB, Bl, FARE (P<0. 05). HIF 3 SAR 6 FUN, PABA SIU(E] 6 S85 DLREAR RRP eS FE SE EX(P>0.05) 4 ihe SLBA te PEARL ULAORE HERR. IE 80 “Fier TELPL Ba 2 PSE THI, UH A AF, BMC OTL a BCU Ae, CLOTS HUA) EAT ST MUL, JEHOME AR ST ACHE, IBO ENPERE RLM AAMT ENDL 5 RA EA 1G, SLRS AOR EE a, RE TER he HSH, oA. IT ALR, ARES BE BORA EY ORL Hs. MOOT GE EL BRA hs Se HG AMET A RCP HL, CAME TS, FEAR AE APSA, Web Ie ARE, HEI I, AB PLR AOE Te TUM IT AR, AE RE is reserved. http://www.enki.ne 2014 £2 A % 21 £% 2 FA BLE PLR AS rs SL Az Af AE I FEE FUP ERBRUERAT, ADSL AOE, (IT BE “HRA aii" HAS, ALR “CLARIDA. ARTE LAL 18 1 ALIBRIS fE AT AAE A BF, PRE DPS Wy 28.5 TA. 1. 2. ERR 40 97. 6, 94. 6%, 92.0%. APU A EGER, WIE FR. DEC. LN, HEROS ACE ORES HAT POLL. TRE HIE TT ET BSR APT, SOME LNM, DE SPA Ke RSE Bs EE 6 3 USO ALBA AS IE I Wi (P-<0, 05). LNMS3 7S A Rb EE AB NM 9 4B), DAE SP TD SO) Pe Rt AE HE 5 FIM Lc WARM. GBS HUIS I SA FAL 25 A299 DPS BAH TALS PALE AP LN BR IEA WBHT SP BTA, LMM 1~9 Ula BY, 005 BAB DPS iF PUERBA A (P<. 05), ‘HAs LN. PAPE SP MO EB aR TZ FG DUREIIPICZS PUI". FRU, A SSE BG BRITE SAEZ, A PS BT ACTA FR, IATA, LNMSS NE Ea RZ PB HEIAIT AT BR RE BE Bi. POURRA SB 1. 2. 3 RPE ERS CBA SIEGEL, ARTUR M (P

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