Department of Clinical

Pharmacology

Case Discussion :
Management of pain
 Case 1

A 34 years old man has just been shifted from

the operation table after an intra-abdominal
operation.

Q1 What analgesic will be prescribed for mild to moderate pain?

Q2 What are the side effects related to the prescribed analgesic?

If the pain is severe and you recommend morphine. Why parenteral

Q3
route is preferred over oral route?
 Case 2

A 60-year-old man presents in the emergency

department with a broken hip suffered in an
automobile accident. He complains of severe pain.
opioid analgesic (morphine IV) was administered.
Q1 What is the mechanism of analgesic effect of morphine?

Q2 what about its use in bronchial asthma?

Q3 Mention its side effects

If the patient is suffering from sever head trauma, would you

Q4 reconsider your choice of analgesic?
 Case 3

A 16-year-old female comes to the physician’s office

because of menstrual cramps. She has been taking
acetaminophen without adequate relief. The problem was
diagnosed as primary dysmenorrhea, and ibuprofen with a
proper dose was administered.
Q1 What are the therapeutic effects of the drug prescribed?

Q2 What is the mechanism of the anti-inflammatory action of this drug?

if the patient is suffering sever gastritis, would you reconsider your

Q3
choice of analgesic
 Case 4

A 6-year-old boy suffering from influenza received an

antipyretic drug for 4 days. On the fifth day, he lapsed into
a coma and died. The autopsy showed diffuse
microvascular fatty infiltration of the liver, as well as
cerebral edema.
Q1 Which antipyretic most likely caused the patient’s death?

Q2 All antipyretics can result in such condition?

Which antipyretic safer to be used in young children?

Q3
Thank You