MCCQE Part I

Study Guide
Table of Contents
Welcome to AMBOSS! . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3

Scoring System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4

Learning content

S01: CARDIOVASCULAR MEDICINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

S02: RESPIRATORY MEDICINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8.

S03: ENDOCRINOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

S04: GASTROENTEROLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12

S05: RENAL MEDICINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

S06: HEMATOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19

S07: INFECTIOUS DISEASES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21

S08: NEUROLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23

S09: ONCOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27

S10:. DERMATOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28

S11: HEAD AND NECK / EYE / EAR NOSE AND THROAT . . . . . . . . . . . . . . . . . . . 30

S12: MUSCULOSKELETAL / ORTHOPAEDICS / RHEUMATOLOGY . . . . . . . . . . . . . . . 33

S13: OBSTETRICS & GYNAECOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36

S14: PSYCHIATRY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38

S15: PEDIATRIC MEDICINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40

S16: NUTRITION / METABOLISM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48

S17: CLINICAL PHARMACOLOGY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49

.

S18: CLINICAL IMMUNOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50

S19: CRITICAL CARE / ANAESTHESIA / EMERGENCY MEDICINE . . . . . . . . . . . . . . . . 51

S20: PUBLIC HEALTH / LAW / ETHICS . . . . . . . . . . . . . . . . . . . . . . . . . . . 52

> Table of Content | 2

Welcome to AMBOSS!
Created by a team of dedicated physicians, AMBOSS is an interactive library of 20,000+ medical topics inter-
linked with a Question Bank with over 5,000 clinical case-based questions. With all the necessary resources
in one place, AMBOSS delivers up-to-date medical knowledge to students, physicians, and faculty around the
world.

In this MCCQE Part I Study Guide, we’ve provided you with a comprehensive checklist of the Medical Expert
Objectives linked to the corresponding AMBOSS articles.

To use this resource for your studies, click on each topic and you will be directed to the assigned articles from
the AMBOSS library. From the articles, you will also be able to access the corresponding questions in the
AMBOSS Qbank.

Click here to open

library articles

Click here to answer

multiple choice questions

We recommend that all candidates read the official MCC “Objectives for the Qualifying Examination” guidelines
before commencing your studies. Links to important Canadian guidelines and clinical resources are also
included in this Study Guide.

With AMBOSS, you’ll be able to study for your exams online, but you can also access our study resources
offline by downloading the AMBOSS Knowledge Library or QBank application for Android and iOS.

Finally, the AMBOSS team is here to support you. If you have questions, suggestions or comments, please
do not hesitate to contact us at hello@amboss.com.

Happy studying!

> Table of Content | 3

MCCQE Part I
Additional tips and resources

The Medical Council of Canada Qualifying Examination (MCCQE) Part I is the standardized, cumulative test for
all medical students wishing to practice medicine in Canada. It is based on the MCC Objectives and covers the
foundational medical knowledge and critical thinking expected of a physician in Canada.

Additional tips and resources are listed below:

General MCCQE Information

https://www.mcc.ca/examinations/mccqe-part-i/

MCCQE Part I Scoring System

https://www.mcc.ca/examinations/mccqe-part-i/scoring/

List of Suggested Reference Materials

https://www.mcc.ca/examinations/list-of-suggested-reference-materials/

Clinical Guidelines- Joule (Canadian Medical Association)

https://joulecma.ca/cpg/homepage

Canadian Task Force on Preventive Health Care

https://canadiantaskforce.ca/

> Table of Content | 4

S01: Cardiovascular Medicine

Theme Topic

Cardiorespiratory arrest Cardiopulmonary resuscitation (CPR)

Cardiovascular examination Cardiovascular examination

Approach to the patient with chest pain ECG

Chest pain

Approach to the patient with edema Edema

Overview of cardiac arrhythmias (Cardiac arrhythmias)

Atrial fibrillation

Arrhythmias Paroxysmal supraventricular tachycardia

Ventricular tachycardia

Ventricular fibrillation

Syncope

Supraventricular premature beats

Sick sinus syndrome

Dysrhythmias
Ventricular premature beats

Atrioventricular block

Long QT syndrome

Acute and chronic heart failure Congestive heart failure

Principles of coronary artery disease

Atherosclerosis

Ischemic heart disease and acute coronary syndromes Acute coronary syndrome

Cardiac catheterization

Coronary artery bypass grafting

Hypertension
Hypertension and hypertensive vascular disease
Renal artery stenosis

> Table of Content | 5

S01: Cardiovascular Medicine

Theme Topic

Valvular heart diseases

Aortic valve stenosis

Aortic regurgitation

Mitral stenosis
Valvular Heart Diseases
Mitral regurgitation

Mitral valve prolapse

Infective endocarditis

Rheumatic fever

Pericarditis

Pericardial disease and myocarditis Myocarditis

Pericardial effusion and cardiac tamponade

Thoracic aortic aneurysm

Abdominal aortic aneurysm (AAA)

Aortic dissection

Aneurysm

Endarterectomy

Vascular diseases of the aorta and limbs

Peripheral arterial disease

Acute limb ischemia

Carotid artery stenosis

Chronic venous disease

Cardiomyopathy Cardiomyopathy

> Table of Content | 6

S01: Cardiovascular Medicine

Theme Topic

Antiarrhythmic drugs

Antiplatelet agents

Oral anticoagulants

Parenteral anticoagulation

Antiadrenergic agents

Beta blockers

Calcium channel blockers (CCB)

Renin-angiotensin-aldosterone system inhibitors

Amiodarone
Cardiac drugs
Nitrates

Phosphodiesterase inhibitors

Cardiac glycosides (Digitalis)

Diuretics

Parasympathomimetic drugs

Muscarinic antagonists

Sympathomimetic drugs

Statins

> Table of Content | 7

S02: Respiratory Medicine

Theme Topic

Approach to the patient with dyspnea Pulmonary examination

Approach to the patient with cough Cough

Airway management and ventilation Airway management and ventilation

Asthma

Chronic obstructive pulmonary disease

Obstructive Pulmonary Diseases
Bronchiectasis

Cystic Fibrosis

Pneumonia

Respiratory infections Acute bronchitis

Tuberculosis

Lung cancer Lung cancer

Interstital pulmonary disease Interstitial lung disease

Pulmonary embolism
Pulmonary vascular disease
Deep vein thrombosis

Pulmonary hypertension and cor pulmonale Pulmonary hypertension and cor pulmonale

Sarcoidosis

Asbestosis
Pneumoconiosis
Silicosis

Rare pneumoconioses

Atelectasis Atelectasis

Acute respiratory distress syndrome Acute respiratory distress syndrome

Pneumothorax
Pleura and mediastinal disorders
Pleural effusion

Upper airway disease Obstructive sleep apnea

> Table of Content | 8

S02: Respiratory Medicine

Theme Topic

Hypersensitivity and anaphylactic reactions

Allergies, anaphylaxis
Hypersensitivity pneumonitis

Shock

Pulmonary function testing

Other Arterial blood gas analysis and pulse oximetry

Beta-2 adrenergic agonists

> Table of Content | 9

S03: ENDOCRINOLOGY

Theme Topic

Principles of endocrinology General endocrinology

Diabetes mellitus

Hyperglycemic crises

Hypoglycemia
Diabetes mellitus
Antidiabetic drugs

Inpatient management of hyperglycemia

Insulin

Lipid Disorders

Dyslipidemias and disorders of lipoprotein metabolism Statins

Second-line lipid-lowering agents

Obesity Metabolic syndrome

Thyroid gland and parathyroid glands

Antithyroid drugs

Goiter

Thyroid antibodies

Hyperthyroidism

Graves disease
Thyroid disorders
Hypothyroidism

Hashimoto’s thyroiditis

Subacute thyroiditis

Thyroid nodules

Thyroid cancer (Thyroid carcinoma)

Thyroid surgery

Hyperparathyroidism
Parathyroid diseases
Hypoparathyroidism

> Table of Content | 10

S03: ENDOCRINOLOGY

Theme Topic

Adrenal diseases Adrenal insufficiency

Primary hyperaldosteronism/Conn syndrome

Cushing’s syndrome

Congenital adrenal hyperplasia

Pheochromocytoma

Metabolic bone disorders Osteomalacia and rickets

Osteoporosis

Bisphosphonates

Laboratory evaluation of bone disease

Paget disease of bone

Hypopituitarism

Hyperprolactinemia
Hypothalamus and pituitary disease

Acromegaly

Pituitary adenoma

Hypogonadism Hypogonadism

Multiple endocrine neoplasia Multiple endocrine neoplasia

Syndrome of inappropriate antidiuretic hormone secretion

Syndrome of inappropriate antidiuretic hormone (SIADH)
secretion (SIADH) and diabetes insipidus
Diabetes insipidus

Breast cancer
Breast disorders
Benign breast conditions

Insulinoma
Other

Glucocorticoids

> Table of Content | 11

S04: GASTROENTEROLOGY

Theme Topic

Nausea and vomiting

Approach to the patient with nausea and vomiting
Case 5: Nausea

Approach to the acute abdomen Acute abdomen

Approach to the patient with dysphagia Case 22: Problems with swallowing

Esophagus

Esophageal cancer

Esophageal perforation

Esophageal barium swallow

Achalasia

Esophageal diverticula

Esophagus, stomach and duodenum Gastroesophageal reflux disease

Peptic ulcer disease

Atrophic gastritis

Gastrinoma (Zollinger-Ellison syndrome)

Gastric cancer

Boerhaave syndrome

Acute pancreatitis

Diseases of the Pancreas

Chronic pancreatitis

Pancreatic Carcinoma

> Table of Content | 12

S04: GASTROENTEROLOGY

Theme Topic

Gastrointestinal bleeding
Approach to the patient with digestive bleeding
Mallory-Weiss syndrome

Case 8: Altered bowel habits

Acute appendicitis

Crohn disease

Ulcerative colitis

Irritable bowel syndrome

Colorectal cancer

Colonic polyps

Lynch syndrome (Hereditary nonpolyposis colon cancer)

Bowel obstruction

Bowel surgery
Diseases of the Small and Large Intestines
Abdominal hernias

Inguinal hernia

Femoral hernia

Internal hernia

Congenital diaphragmatic hernias

Acquired diaphragmatic hernia

Malabsorption

Coeliac disease

Lactose intolerance

Intestinal ischemia

> Table of Content | 13

S04: GASTROENTEROLOGY

Theme Topic

Diarrhea

Food poisoning

Bacterial gastroenteritis

Norovirus infection

Rotavirus infection
Diarrhea, gastroenteritis and food borne
gastric infections
Botulism

Diarrheagenic E. coli

Clostridium difficile infection

Amebiasis

Giardiasis

Rectal prolapse

Hemorrhoids

Thrombosed external hemorrhoid

Anorectal Disorders Anal fissures

Anal abscess and fistula

Anal cancer

Pilonidal cyst

Approach to the jaundiced patient Jaundice and cholestasis

Cirrhosis

Alcoholic liver disease

Ascites

Diseases of the liver Portal hypertension

Wilson disease

Hemochromatosis

Autoimmune hepatitis

> Table of Content | 14

S04: GASTROENTEROLOGY

Theme Topic

Hepatitis A

Hepatitis B

Hepatitis C
Diseases of the liver
Hepatocellular carcinoma

Benign Liver tumors and hepatic cysts

Pyogenic liver abscess

Cholelithiasis, choledocholithiasis, cholecystitis, and cholangitis

Primary biliary cholangitis

Gallbladder and biliary tract diseases Primary sclerosing cholangitis

Cholangiocarcinoma

Inherited hyperbilirubinemia (Gilbert's syndrome)

Proton pump inhibitors

Meckel diverticulum
Other
Pancreatic and hepatic surgery

Carcinoid tumor

> Table of Content | 15

S05: RENAL MEDICINE

Theme Topic

Diagnostic evaluation of the kidney and urinary tract

Approach to the patient with urinary abnormalities
Dehydration

Sodium disorders

Disorders of potassium balance

Fluid and electrolyte imbalances
Disorders of calcium balance

Syndrome of inappropriate antidiuretic hormone secretion

(SIADH)

Diabetes insipidus

Acute kidney injury

Pyelonephritis

Urinary tract infections

Acute kidney and urinary tract diseases
Urethritis

Nephrolithiasis

Hematuria

Chronic kidney disease

Renal cell carcinoma

Urothelial cancer

Urinary incontinence

Stress incontinence
Chronic kidney and urinary tract diseases
Urge incontinence

Urinary retention

Urinary tract obstruction

Vesicoureteral reflux

Retroperitoneal fibrosis

> Table of Content | 16

S05: RENAL MEDICINE

Theme Topic

Glomerular diseases

IgA nephropathy (Berger disease)

Poststreptococcal glomerulonephritis

Glomerular diseases Rapidly progressive glomerulonephritis

Nephrotic syndrome

Nephritic syndrome

Proteinuria

Renal Artery Stenosis Renal Artery Stenosis

Congenital anomalies of the kidneys

Hereditary renal disorders Polycystic Kidney Disease

Renal tubular disorders

Tubulointerstitial diseases Tubulointerstitial diseases

Benign prostatic hyperplasia

Prostate Prostatitis

Prostate cancer

Bladder exstrophy, abnormalities of the male urethra,

and webbed penis

Disorders of the glans penis and foreskin

Scrotal abnormalities

Epididymitis

Male reproductive system Testicular tumors

Carcinoma of the penis

Genitourinary trauma

Testicular torsion

Priapism

> Table of Content | 17

S05: RENAL MEDICINE

Theme Topic

Penile fracture

Male reproductive system Erection and ejaculation disorders

Semen analysis

Edema

Renal replacement therapy

Other
Diagnostic investigations in urology

Diuretics

> Table of Content | 18

S06: HEMATOLOGY

Theme Topic

Basics of haematology Basics of hematology

Approach to the patient with adenopathy Splenomegaly

and splenomegaly
Lymphadenopathy

Anemia

Iron deficiency anemia

Hemolytic anemia

Hereditary spherocytosis

Anemias Glucose-6-phosphate dehydrogenase deficiency

Sickle cell anemia

Vitamin B12 deficiency

Porphyrias

Hemolytic uremic syndrome (HUS)

Hodgkin lymphoma

Lymphomas Non-Hodgkin lymphomas

MALT lymphoma

Acute leukemia

Leukemias Chronic myeloid leukemia

Chronic lymphocytic leukemia

Hemostasis and bleeding disorders

Hemophilia
Coagulation and bleeding disorders
Hypercoagulable states

Disseminated intravascular coagulation

Haemoglobinopathies Thalassemia

Myelodysplastic syndromes
Myelodysplastic syndromes
Polycythemia vera

Myeloma and plasma cell disorders Multiple myeloma

> Table of Content | 19

S06: HEMATOLOGY

Theme Topic

Blood products Transfusion

Thrombocytopenia
Platelet and vascular wall disorders
Thrombotic thrombocytopenic purpura

Myeloproliferative neoplasms Myeloproliferative neoplasms

Amyloidosis Amyloidosis

Antiplatelet agents

Parenteral anticoagulation

Oral anticoagulants

Erythrocyte morphology and hemoglobin

Other
Myeloproliferative neoplasms

Mycosis fungoides
(Cutaneous T-cell lymphoma)

Antiphospholipid syndrome

Asplenia

> Table of Content | 20

S07: INFECTIOUS DISEASES

Theme Topic

Bacteria overview
Principles of microbiology
General mycology

Approach to the patient with fever Fever and inflammation

The flu Influenza

Sepsis
Sepsis and septic shock

Shock

Human immunodeficiency virus (HIV)

HIV/AIDs

HIV-associated conditions

Hospital acquired infections Nosocomial infections

Syphilis Syphilis

Sexually transmitted infections

Candidiasis

Gonorrhea

Chancroid

Sexually transmitted diseases Herpes simplex virus infections

Cytomegalovirus infection

Chlamydia infections

Pelvic inflammatory disease

Granuloma inguinale

Legionnaires disease Legionellosis

Collection of zoonotic diseases

Lyme disease (Borreliosis)

Typhoid fever, Paratyphoid fever

Leptospirosis

Zoonoses and arthropod-borne infections

Diphtheria

Listeriosis

> Table of Content | 21

S07: INFECTIOUS DISEASES

Theme Topic

Dengue

Malaria
Zoonoses and arthropod-borne infections
Toxoplasmosis

Yellow fever

Zika virus infection

Immunosuppressants

Pneumocystis pneumonia
Immunosuppression

Transplantation

Aspergillosis

Mononucleoside syndromes Infectious mononucleosis/Epstein Barr Virus

Traveler’s diarrhea
Traveller’s diseases
Immunizations for travel

Vaccination

Immunization schedule

Overview of antibiotic therapy

Antiviral agents

Other Antifungals

Chloroquine and hydroxychloroquine

Staphylococcal diseases

Finger infections

Tetanus

> Table of Content | 22

S08: NEUROLOGY

Theme Topic

Neurological examination Neurological examination

Headache

Migraine

Tension headaches
Approach to the patient with headache
Cluster headache

Elevated intracranial pressure and brain herniation

Dissection of the carotid and the vertebral artery

Approach to the patient with syncope Syncope

Lumbar Puncture Lumbar puncture

Cranial nerve palsies

Cranial nerve disorders Trigeminal neuralgia

Facial nerve palsy/Bell palsy

Disorders of the visual pathway Disorders of the visual pathway

Parkinson disease

Parkinson-plus syndromes

Medication for Parkinson disease

Huntington‘s disease
Movement disorders
Dystonia

Tremor

Tourette syndrome

Spasticity

Cerebellum

Cerebellar syndromes
Cerebellar disorders
Wernicke encephalopathy and Korsakoff syndrome

Spino-cereballar ataxia

> Table of Content | 23

S08: NEUROLOGY

Theme Topic

Meningitis

Infections of nervous system

Herpes simplex encephalitis

Brain abscess

Complete spinal cord injury

Spinal disorders Incomplete spinal cord syndromes

Syringomyelia

Spinal stenosis

Bulbar palsy and pseudobulbar palsy

Carpal tunnel syndrome

Diabetes mellitus (diabetic neuropathy)

Median nerve neuropathy

Peripheral neuropathy Neuralgic amyotrophy

Peripheral nerve injuries

Polyneuropathy

Radial neuropathies

Ulnar nerve entrapment

Motor neuron diseases Amyotrophic lateral sclerosis

Spinal muscular atrophy

Neurodegenerative Hereditary spastic paraplegia

Multiple sclerosis Multiple sclerosis

Myasthenia gravis
Neuromuscular junction diseases
Botulism

Guillain-Barre syndrome Guillain-Barré syndrome

Muscular dystrophies Progressive muscular dystrophies

Myopathies Myotonic syndromes

Pain syndromes Complex regional pain syndrome

> Table of Content | 24

S08: NEUROLOGY

Theme Topic

Seizure disorders (Epilepsy)

Seizure disorders and epilepsy Focal seizures and syndromes

Anticonvulsant drugs

Narcolepsy
Sleep disorders
Restless legs syndrome

Cerebrovascular system

Stroke

Locked-in syndrome

Wallenberg syndrome (lateral medulla syndrome)

Cerebral aneurysms

Cerebrovascular system Cerebral venous thrombosis

Carotid-cavernous fistula

Epidural hematoma

Subdural hematoma

Subarachnoid hemorrhage

Intracerebral hemorrhage

Traumatic brain injury Traumatic brain injury

Brain tumours

Astrocytoma
Brain tumours

Meningioma

Acoustic neuroma

Elevated intracranial pressure and brain herniation

Intracranial pathology
Idiopathic intracranial hypertension

Hydrocephalus Hydrocephalus

> Table of Content | 25

S08: NEUROLOGY

Theme Topic

Rare neurological diseases

Transient global amnesia

Other Skull base syndromes

Creutzfeldt-Jakob disease

Myelopathy

> Table of Content | 26

S09: ONCOLOGY

Theme Topic

Principles of oncology General oncology

Disorders of calcium balance

Superior Vena Cava Syndrome

Oncological emergencies

Spinal cord compression

Brain metastases

Disordered cell growth Tumor markers

Palliation Overview of palliative medicine

Chemotherapeutic agents

Principles of cancer treatment Opioids

Antiemetics

Paraneoplastic syndromes Paraneoplastic syndromes

> Table of Content | 27

S10: DERMATOLOGY

Theme Topic

Principles of dermatology

Principles of dermatology Benign skin lesions

Collection of dermatological disorders

Precancerous skin lesions

Melanoma
Skin cancers
Squamous cell carcinoma

Basal cell carcinoma (Basalioma)

Skin and soft tissue infections

Gas gangrene (Clostridial myonecrosis)

Shingles

Molluscum contagiosum

Impetigo

Skin and soft tissue infections Staphylococcal scalded skin syndrome

Dermatophyte infections

Tinea versicolor (Pityriasis versicolor)

Scabies

Lice infestation

Erythrasma

Atopic dermatitis

Contact dermatitis

Dermatitis (Eczema) Seborrheic dermatitis

Stasis Dermatitis

Lichen Simplex Chronicus

Wound treatment
Wounds
Wound healing

Burns Burns

> Table of Content | 28

S10: DERMATOLOGY

Theme Topic

Acne vulgaris
Acneiform Eruptions
Rosacea

Lichen planus

Papulosquamous Diseases Pityriasis rosea

Psoriasis

Autoimmune blistering diseases

Vesiculobullous Diseases
Porphyrias

Ichthyosis

Heritable Disorders Vitiligo

Neurocutaneous syndromes

Stevens-Johnson syndrome

Aphthous stomatitis

Alopecia

Other Photodermatoses

Angioedema

Erythema nodosum

Erythema multiforme

> Table of Content | 29

S11: HEAD AND NECK / EYE / EAR NOSE
AND THROAT
Theme Topic

Ocular trauma Traumatic eye injuries

Eye and orbit

Orbit
Orbital disorders

Lacrimal apparatus Diseases of the lacrimal apparatus

Lids and lashes Inflammation of the eyelids

Conjunctivitis
Conjunctiva
Pterygium

Sclera Scleritis and episcleritis

Cornea Corneal disorders

Diseases of the uvea

Uveal tract
Uveal melanoma

Diseases of the lens

Lens
Cataract

Diseases of the vitreous body

Vitreous
Endophthalmitis

Diseases of the retina

Retinal vessel occlusion

Retina
Retinal detachment

Age-related macular degeneration

Glaucoma Glaucoma

Pupils Physiology and abnormalities of the pupil

Horner syndrome

Opthalmology miscellaneous Keratitis

Ocular motility disorders and strabismus

> Table of Content | 30

S11: HEAD AND NECK / EYE / EAR NOSE
AND THROAT
Theme Topic

Hearing loss

The Ear

Otitis externa (Swimmer’s ear)

Acute otitis media (Middle ear infection)

Ear Chronic otitis media

Cholesteatoma

Otosclerosis

Ménière disease

Tinnitus

Case 40: Dizziness

Benign paroxysmal positional vertigo

Dizziness and Vertigo Vestibular Neuronitis (labyrinthitis)

Acoustic neuroma (vestibular schwannoma)

Phobic postural vertigo

Rhinitis
Rhinosinusitis

Sinusitis

Epistaxis
Nose

Nasal papilloma

> Table of Content | 31

S11: HEAD AND NECK / EYE / EAR NOSE
AND THROAT
Theme Topic

Acute tonsillitis

Larynx

Laryngitis

Throat Laryngeal carcinoma

Pharyngeal cancer

Juvenile nasopharyngeal angiofibroma

Adenoid hypertrophy

Miscellaneous ear, nose, and throat disorders

Miscellaneous ear, nose, and throat disorders
Diseases of the salivary glands

Head and Neck Examination

Overview of head and neck region

Head and Neck

Deep neck infections

Congenital neck masses

> Table of Content | 32

S12: MUSCULOSKELETAL / ORTHOPAEDICS /
RHEUMATOLOGY
Theme Topic

Adaptive immune system

Principles of immunology and rheumatology Autoantibodies in rheumatic diseases

Immunosuppressants

Rheumatoid arthritis

Systemic lupus erythematosus

Antiphospholipid syndrome

Systemic connective tissue disease Systemic sclerosis (Scleroderma)

Inflammatory myopathies (Myositis)

Sjögren’s Syndrome

Connective tissue diseases

Seronegative spondyloarthropathies

Ankylosing spondylitis
Seronegative rheumatic disease
Reactive arthritis (Reiter syndrome)

Psoriasis

Vasculitides

Kawasaki disease

Giant cell arteritis (Temporal arteritis)

Granulomatosis with polyangiitis

Vasculitides
(Wegener granulomatosis)

Thromboangiitis obliterans

Raynaud phenomenon

Henoch-Schonlein purpura

Gout and other microcrystalline arthropathies Gout and hyperuricemia

Osteoarthritis
Degenerative joint disease
Osteoarthritis of the hip and knee

Fibromyalgia
Non-articular rheumatism
Polymyalgia rheumatica

> Table of Content | 33

S12: MUSCULOSKELETAL / ORTHOPAEDICS /
RHEUMATOLOGY
Theme Topic

Bone tumours Benign bone tumors

Malignant bone tumors

Compartment syndrome Compartment syndrome

General principles of fractures

General principles of fractures
Conservative treatment of fractures
(Conservative fracture management)

Shoulder, axilla, and brachial plexus

Shoulder dislocation
Shoulder
Soft tissue lesions of the shoulder

Biceps tendon tear

Clavicle Clavicle fracture

Upper arm and elbow

Humerus fracture

Humerus and elbow Insertional tendiopathy (epicondylitis)

Elbow dislocation

Radial head subluxation (Pulled elbow)

Forearm, wrist and hand

Scaphoid fracture

Forearm, wrist and hand Distal radius fractures

Finger injuries

Dupuytren’s contracture

Vertebral fractures

Spondylolisthesis
Spine
Degenerative disc disease

Torticollis

Pelvis Pelvic fracture

Hip Hip fractures

> Table of Content | 34

S12: MUSCULOSKELETAL / ORTHOPAEDICS /
RHEUMATOLOGY
Theme Topic

The leg, ankle and foot

Femur Femoral shaft fracture

Osteonecrosis of the femoral head

Patellar dislocation

Knee and patellar Knee ligament injuries

Meniscus tear (Meniscus rupture)

Tibia Tibial fracture

Ankle fracture

Ankle and foot Achilles tendon rupture

Foot deformities

Sports injuries Sports injuries

Pediatric fractures Pediatric fractures

Septic arthritis (Infectious arthritis)

Bone and joint infections
Osteomyelitis

Collection of orthopedic conditions

Thoracic outlet syndrome

Other (orthopedics)
Osteochondritis dissecans

Tenosynovitis

> Table of Content | 35

S13: OBSTETRICS & GYNAECOLOGY

Theme Topic

Menopause, urogynaecology and prolapse Diagnostic procedures in gynecology

Menopause

Pelvic organ prolapse

Stress incontinence

Urinary incontinence

Urinary tract infections

Anomalies of the female genital tract

Oncology and gynaecological surgery Human papillomavirus infection

Cervical cancer (Cervical carcinoma)

Breast cancer

Vulvar and vaginal cancer

Ovarian tumors

Menstrual cycle and menstrual cycle abnormalities

Hypogonadism
Menstrual cycle, puberty and hormones
Estrogen and associated diseases

Disorders of sex development

Endometriosis

Endometrial cancer

Uterine leiomyoma (Fibroids)

Polycystic ovary syndrome (PCOS)

Vaginal bleeding
Pregnancy loss

Ectopic pregnancy

Vulvovaginitis

Sexually transmitted infections

> Table of Content | 36

S13: OBSTETRICS & GYNAECOLOGY

Theme Topic

Infertility

Nonhormonal contraception

Contraception, preconception and infertility Hormonal contraceptives

Prenatal care

Pregnancy

The placenta, umbilical cord, and amniotic sac

Hypertensive pregnancy disorders

Gestational diabetes mellitus

Gestational trophoblastic disease

Antenatal care, fetal wellbeing and medical
disorders in pregnancy Placental insufficiency

Multiple pregnancy

Intrauterine growth restriction

Pharmacotherapy during pregnancy

Chorioamnionitis, neonatal infection and omphalitis.

Childbirth

Mechanics of childbirth

Labour and birthing Uterine rupture

Preterm labor and birth

Congenital TORCH infections

Birth traumas

Obstetric emergencies Postpartum hemorrhage

Antepartum hemorrhage

Postpartum period
Puerperium
Prenatal and postnatal physiology

> Table of Content | 37

S14: PSYCHIATRY

Theme Topic

Autism spectrum disorder

Tourette syndrome
Neurodevelopmental disorders
Emotional and behavioral disorders in children and adolescents

Attention deficit hyperactivity disorder

Personality disorders
Personality disorders
Disruptive, impulse-control, and conduct disorders

Psychosomatic Somatic symptom and related disorders

Schizophrenia

Delusional disorder

Psychosis Bipolar disorder

Lithium

Antipsychotics

Major depressive disorder

Anxiety disorders
Depressive and anxiety disorders
Antidepressants

Suicidality

Obsessive compulsive disorders Obsessive-compulsive disorder

Feeding and eating disorders Eating disorders

Trauma- and stressor-related disorders Trauma- and stressor-related disorders

Dissociative disorders Dissociative disorders

Elimination disorders Elimination disorders

Sleep wake disorders Sleep disorders

Sedative hypnotic drugs

> Table of Content | 38

S14: PSYCHIATRY

Theme Topic

Sexual dysfunctions Sexuality and sexual medicine

Alcohol use disorder (Alcoholism)

Substance related and addictive disorders Substance-related and addictive disorders

Wernicke encephalopathy and Korsakoff syndrome

Major neurocognitive disorder

Delirium

Alzheimer’s disease
Neurocognitive disorders
Vascular dementia

Frontotemporal dementia

Parkinson-plus syndromes

Psychotherapy and defense mechanisms

Other Electroconvulsive therapy (ECT)

Anticonvulsant drugs

> Table of Content | 39

S15: PEDIATRIC MEDICINE

Theme

NEONATOLOGY

The newborn infant

Birth traumas

Neonatal respiratory distress syndrome

Teratogenic birth defects

Assessment and care and major problems of Intrauterine Growth Restriction

the newborn
Congenital visceral malformations

Hemolytic disease of the fetus and newborn

Vitamin K deficiency bleeding of the newborn

Sudden infant death syndrome

Neonatal jaundice Neonatal jaundice (Icterus neonatorum)

Neonatal screening The newborn infant

Congenital TORCH infections

Infectious diseases in pregnancy affecting the newborn HIV in pregnancy

Perinatal hepatitis B

Hypertensive pregnancy disorders

Pregnancy disorders affecting the newborn Gestational diabetes mellitus

Hyperthyroidism in pregnancy

Neonatal sepsis Chorioamnionitis, neonatal infection, and omphalitis

CHILD DEVELOPMENT, MILESTONES, AND GROWTH

Child development and milestones Child development and milestones

> Table of Content | 40

S15: PEDIATRIC MEDICINE

Theme

GENERAL PAEDIATRICS

Normal growth Child development and milestones

National program for Child and Youth Health See recommended resources

Vaccination
National Vaccination Program
Immunization schedule

CARDIOLOGY

Acyanotic congenital heart defects

Congenital heart defects
Cyanotic congenital heart defects

HAEMATOLOGY/ONCOLOGY

Anemia
Anaemia
Thalassemia

Diagnostic approach and referral criteria

Acute leukemia
for paediatric neoplasia

Neuroblastoma

Common paediatric tumours Wilms tumour (Nephroblastoma)

Retinoblastoma

ENDOCRINOLOGY, NUTRITION AND GROWTH

Puberty disorders Puberty

Disorders of sex development

Tall stature and abnormally rapid growth

Disordered growth Metabolic syndrome

Short stature

Diabetes Mellitus Diabetes mellitus

> Table of Content | 41

S15: PEDIATRIC MEDICINE

Theme

INFECTIOUS DISEASES

Measles

Mumps

Scarlet fever (Second disease)

Rubella

Fifth disease (Erythema infectiosum)

Roseola infantum

Chickenpox

Atopic dermatitis

Seborrheic dermatitis
Dermatology and rashes
Acne vulgaris

Herpes simplex virus infections

Molluscum contagiosum

Impetigo

Staphylococcal scalded skin syndrome

Dermatophyte infections

Tinea versicolor (Pityriasis versicolor)

Scabies

Lice infestation

Fever and inflammation

Approach to the child with fever
Febrile seizures (Febrile seizure)

Sepsis Sepsis

> Table of Content | 42

S15: PEDIATRIC MEDICINE

Theme

NEUROLOGY

Meningitis
Neurological infections

Poliomyelitis

Craniosynostosis

Hydrocephalus
Neurology

Craniovertebral junction anomalies

Neural tube defects

Seizure disorders

Seizure disorders and febrile convulsions

Generalized epilepsy in childhood

Febrile seizures (Febrile seizure)

CHILD PSYCHIATRY AND NEURODEVELOPMENT

Child development and milestones

Disruptive, impulse-control, and conduct disorders

Child psychiatry and neurodevelopmental disorders Chromosomal aberrations

Autism spectrum disorder

Attention deficit hyperactivity disorder

Cerebral Palsy

Maltreatment in child and youth Child maltreatment

> Table of Content | 43

S15: PEDIATRIC MEDICINE

Theme

PULMONOLOGY

Bronchiolitis

Croup
Respiratory tract infections
Pertussis

Acute bronchitis

Recurrent wheezing and asthma Asthma

Hypersensitivity reactions
Urticaria, angioedema and anaphylaxis
Angioedema

Obstructive sleep apnoea Obstructive sleep apnoea

Food allergy Food allergies

Cystic fibrosis Cystic fibrosis

GASTROENTEROLOGY

Hypertrophic pyloric stenosis

Gastroesophageal reflux

Acute appendicitis

Esophageal atresia

Duodenal atresia and stenosis

Approach to the vomiting child

Hirschsprung’s disease

Necrotizing enterocolitis

Intussusception

Volvulus and intestinal malrotation

Meckel diverticulum

Inguinal hernia

Approach to children with acute abdominal pain Testicular torsion

Ovarian torsion

Henoch-Schonlein purpura

> Table of Content | 44

S15: PEDIATRIC MEDICINE

Theme

GASTROENTEROLOGY

Approach to the constipated child Constipation

Diarrhea

Malabsorption

Celiac disease
Approach to the child with chronic diarrhoea
and malabsorption Crohn disease

Ulcerative colitis

Lactose intolerance

Irritable bowel syndrome

Bacterial gastroenteritis

Diarrheagenic E. coli
Acute gastroenteritis
Rotavirus infection

Diarrhea

Approach to the dehydrated child Dehydration

OPTHALMOLOGY AND ENT

Conjunctivitis

Ophthalmology Strabismus

Orbital cellulitis

Acute otitis media

Ear Chronic otitis media

Otitis externa

Acute tonsilitis

Laryngitis

Epiglottitis
Nose and throat

Sinusitis

Rhinitis

> Table of Content | 45

S15: PEDIATRIC MEDICINE

Theme

NEPHROLOGY

Urinary tract infections Urinary tract infections

Nephrotic syndrome Nephrotic syndrome

Congenital anomalies of the kidneys

Bladder exstrophy, abnormalities of the male urethra,

Renal and urinary tract malformations
and webbed penis

Vesicoureteral reflux

Nephritic syndrome
Glomerulonephritis
Poststreptococcal glomerulonephritis

Henoch-Schönlein purpura

Enuresis Elimination disorders

MUSCULOSKELETAL

Developmental dysplasia of the hip

Legg-Calvé-Perthes disease

Slipped capital femoral epiphysis

Orthopedics Osgood Schlatter disease

Transient synovitis

Juvenile idiopathic arthritis

Idiopathic scoliosis

Osteomyelitis and infectious arthritis Septic arthritis

Osteomyelitis

Muscular dystrophy Progressive muscular dystrophies

Muscular atrophy Spinal muscular atrophy

OTHERS

Cardiopulmonary resuscitation

Paediatric basic life support Foreign body aspiration (FBA)

Parenteral fluid therapy

> Table of Content | 46

S15: PEDIATRIC MEDICINE

Theme

CONGENITAL AND INHERITED DISORDERS

Basics of human genetics

Down syndrome (Trisomy 21)

Ehlers-Danlos syndrome and Marfan syndrome

Inherited hyperbilirubinemia

Inborn errors of carbohydrate metabolism

Congenital immunodeficiency disorders

Cleft lip and cleft palate (Cleft lip)

Congenital adrenal hyperplasia

Inborn errors of metabolism

Rare inherited syndromes

Choanal atresia

Neurocutaneous syndromes

> Table of Content | 47

S16: NUTRITION / METABOLISM

Theme Topic

Specialised nutrition support

Vitamins

Nutrition Vitamin B12 deficiency

Folate deficiency

Malabsorption

Inborn errors of metabolism

Lipids and fat metabolism

Metabolism Inborn errors of carbohydrate metabolism

Glycogen metabolism

Glycolysis and gluconeogenesis

Intravenous fluid therapy

Electrolyte repletion

Normal fluid and electrolyte imbalance Sodium disorders

Potassium disorders

Calcium disorders

Acid-base balance Acid base disorders

> Table of Content | 48

S17: CLINICAL PHARMACOLOGY

Theme Topic

Fundamentals of pharmacology Fundamentals of pharmacology

Salicylate toxicity

Metal toxicity
Toxicity and poisoning
Organic solvent toxicity

Poisoning

> Table of Content | 49

S18: CLINICAL IMMUNOLOGY

Theme Topic

Lymphatic system

Lymphatics Lymphatic techniques

Lymphadenopathy

Transplantation Transplantation

Adaptive immune system

Immunology Innate immune system

Congenital immunodeficiency disorders

> Table of Content | 50

S19: CRITICAL CARE/ANAESTHESIA/
EMERGENCY MEDICINE
Theme Topic

Management of trauma patients

Penetrating trauma

Blunt trauma

Splenic rupture

Trauma General treatment of fractures

Nonthrombotic embolism

Rhabdomyolysis and crush syndrome

Compartment syndrome

Airway management and ventilation

Perioperative management
Surgery
Laparoscopic surgery

Airway management and ventilation Airway management and ventilation

Pain management

Opioids

Local anesthetic agents

Local and regional anesthesia

Anaesthesia Non-opioid analgesics

Inhalational anesthetics

Intravenous anaesthetics

Skeletal muscle relaxants

Benzodiazepines

Malignant hyperthermia

Other Parenteral fluid therapy

Hypothermia and frostbite

> Table of Content | 51

S20: PUBLIC HEALTH / LAW / ETHICS

Theme Topic

Investigations Laboratory medicine

Death

Grief and end-of-life counseling

Overview of palliative medicine

Medical law and ethics
Patient communication and counseling

Principles of medical law and ethics

Quality and safety

Epidemiology Epidemiology

Infection prevention and control

If you have completed this study guide, you will have covered all of the requirements for the ‘Medical Expert’
objectives outlined by the Medical Council of Canada. However, you will also need to consult other resources
for Canadian medical ethics, laws, and healthcare systems. To do this, you will find a list of resources here.
Specifically, you should supplement this Study Guide with resources covering these topics:

Population Health and Its Determinants

Concepts of Health and Its Determinants
Disaster Preparedness, Emergency Response, and Recovery
Assessing and Measuring Health Status at the Population Level
Interventions at the Population Level
Administration of Effective Health Programs at the Population Level
Outbreak Management
Environment
Health of Special Populations
Work-related Health Issues
Indigenous Health

Legal, Ethical and Organizational Aspects of Medicine

Consent
Truth Telling
Negligence
Confidentiality
Legal System

> Table of Content | 52