Clinical Significance:- Variations in plasma proteins concentration occur due to one or more of the following changes:- eee Ree ee Pee RRR eC ER mR memes ileI-hypo-albuminaemia: or hypo-proteinaemi Lert Svea a- Decrease in the rate of protein synthesis: - asin liver disease, and malabsorption (diarrhea), malnutrition b- Increase in the rate of protein excretion finc. protein loss, EO a CGO Rec oa aa ue em) foes tetera ne Pome alate Sem ame) TA Le as in: over hydration, hypoxia and septicemia. Il-hyper-albuminaemia. Ve actRcrs eck atom loulm eects ie ce EM ahd slotmer claims (e) el are =la lt a Due to increase the rate of synthesis of gamma-globulins as in cancer. V-Hypo -gamma-globulinaemia:- are cue Me aM Re aL aa Cee tag al setePROCEDURE Ts Sample Standard Fsidad = ere URC ea OO R UC Le Ue aeL OTLClinical Significance:- Variations in plasma proteins concentration occur due to one or more of the following changes:- eee Ree ee Pee RRR eC ER mR memes ileI-hypo-albuminaemia: or hypo-proteinaemi Lert Svea a- Decrease in the rate of protein synthesis: - asin liver disease, and malabsorption (diarrhea), malnutrition b- Increase in the rate of protein excretion finc. protein loss, EO a CGO Rec oa aa ue em) foes tetera ne Pome alate Sem ame) TA Le as in: over hydration, hypoxia and septicemia. Il-hyper-albuminaemia. Ve actRcrs eck atom loulm eects ie ce EM ahd slotmer claims (e) el are =la lt a Due to increase the rate of synthesis of gamma-globulins as in cancer. V-Hypo -gamma-globulinaemia:- are cue Me aM Re aL aa Cee tag al setePrinciple of assay:- Colourimetric determination of total plasma proteins based on the principle of Peace il eae claus Cu +OH +PROTEIN--- PIC MCle mul cltuel nck cum Siee Meda acne? Oran aac our og) Biuret reagent formed of: 1-CUSO4. 5 H20: as chromogene (Complexing agent). 2- NaOH: For alkaline medium en potassium tartarate: To help complex formation and maintain its Bele) lia CE Sea ale (oe Codie NBER Colao) oreo Lele MaLt re ea raed old Lae A Loe CeO NCCE} acids and dipeptides give -ve test and > this test is used for detection of complete protein hydrolysis.PROCEDURE Ts Sample Standard Fsidad = ere URC ea OO R UC Le Ue aeL OTLClinical Significance:- Variations in plasma proteins concentration occur due to one or more of the following changes:- eee Ree ee Pee RRR eC ER mR memes ileI-hypo-albuminaemia: or hypo-proteinaemi Lert Svea a- Decrease in the rate of protein synthesis: - asin liver disease, and malabsorption (diarrhea), malnutrition b- Increase in the rate of protein excretion finc. protein loss, EO a CGO Rec oa aa ue em) foes tetera ne Pome alate Sem ame) TA Le as in: over hydration, hypoxia and septicemia. Il-hyper-albuminaemia. Ve actRcrs eck atom loulm eects ie ce EM ahd slotmer claims (e) el are =la lt a Due to increase the rate of synthesis of gamma-globulins as in cancer. V-Hypo -gamma-globulinaemia:- are cue Me aM Re aL aa Cee tag al setePrinciple of assay:- Colourimetric determination of total plasma proteins based on the principle of Peace il eae claus Cu +OH +PROTEIN--- PIC MCle mul cltuel nck cum Siee Meda acne? Oran aac our og) Biuret reagent formed of: 1-CUSO4. 5 H20: as chromogene (Complexing agent). 2- NaOH: For alkaline medium en potassium tartarate: To help complex formation and maintain its Bele) lia CE Sea ale (oe Codie NBER Colao) oreo Lele MaLt re ea raed old Lae A Loe CeO NCCE} acids and dipeptides give -ve test and > this test is used for detection of complete protein hydrolysis.PROCEDURE Ts Sample Standard Fsidad = ere URC ea OO R UC Le Ue aeL OTL