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CPR-01473; No of Pages 11

Clinical Psychology Review xxx (2015) xxx–xxx

Contents lists available at ScienceDirect

Clinical Psychology Review

Remote cognitive–behavior therapy for obsessive–compulsive


symptoms: A meta-analysis
Bethany M. Wootton ⁎
Department of Medicine (Psychology), University of Tasmania, Locked Bag 30, Hobart, TAS 7001, Australia

H I G H L I G H T S

• This study synthesizes the findings on remote treatment for obsessive–compulsive symptoms using a meta-analytic approach.
• Eighteen controlled and uncontrolled studies were included in the meta-analysis.
• Remote treatment for OCD produces a large effect size.
• Remote treatment for OCD is significantly more effective than control.
• Outcomes from remote treatment do not differ from face-to-face treatment.

a r t i c l e i n f o a b s t r a c t

Article history: Obsessive–compulsive disorder (OCD) is a chronic mental health condition that results in a significant societal
Received 17 March 2015 burden. Remote treatments do not require the patient to attend traditional face-to-face treatment services and
Received in revised form 4 October 2015 can be used as a way to overcome barriers to accessing face-to-face treatment. The aim of the current study
Accepted 13 October 2015
was to synthesize the current literature on remote treatment for OCD using a meta-analytic approach. Relevant
Available online xxxx
articles were identified through an electronic database search and the references of previously completed re-
Keywords:
views on the topic of remote treatment for OCD were also reviewed. Eighteen studies (n = 823; mean age =
Obsessive–compulsive disorder 31.20 (SD = 10.36); 56.2% female) were included in the meta-analysis. Within-group findings indicate that re-
Remote-treatment mote treatment for OCD produces a decrease in symptoms of a large magnitude (g = 1.17; 95% CI: 0.91–1.43).
Meta-analysis Between-group findings indicate that remote treatment for OCD is more effective than control (g = 1.06; 95%
CI: 0.68–1.45) and outcomes are not meaningfully different from face-to-face treatment (g = −0.21; 95% CI:
−0.43–0.02). Those methodologies that are low intensity produce a decrease in symptoms of a large magnitude
(g = 1.36, 95% CI: 1.00–1.72), as do higher intensity treatments (g = 1.64, 95% CI: 1.33–1.95). These findings
have important implications for the development of stepped-care treatments, which may be able to be delivered
in a purely remote fashion.
© 2015 Elsevier Ltd. All rights reserved.

Contents

1. Measurement of obsessive–compulsive symptoms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0


2. Cognitive–behavioral treatment for obsessive–compulsive disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
3. Barriers to accessing evidence-based treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
4. Remote treatment for obsessive–compulsive disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
4.1. High intensity remote treatments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
4.1.1. Videoconferencing administered CBT (vCBT) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
4.1.2. Telephone administered CBT (tCBT) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
4.2. Low intensity remote treatments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
4.2.1. Computerized CBT (cCBT) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
4.2.2. Internet-administered CBT (iCBT) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
4.2.3. Bibliotherapy administered CBT (bCBT) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
5. Method . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0

⁎ Tel.: +61 3 6226 7124; fax: +61 3 6226 2883.


E-mail address: bethany.wootton@utas.edu.au.

http://dx.doi.org/10.1016/j.cpr.2015.10.001
0272-7358/© 2015 Elsevier Ltd. All rights reserved.

Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
chology Review (2015), http://dx.doi.org/10.1016/j.cpr.2015.10.001
2 B.M. Wootton / Clinical Psychology Review xxx (2015) xxx–xxx

5.1. Search procedure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0


5.2. Study selection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
5.3. Data analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6. Results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6.1. Study characteristics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6.2. Within-group analyses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6.2.1. Overall within-group effect size for remote treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6.2.2. Low intensity vs. high intensity remote treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6.2.3. Self-guided vs clinician-guided low intensity treatments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6.3. Between-group analyses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6.3.1. Remote treatment vs. control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
6.3.2. Remote treatment vs. face-to-face treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
7. Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
7.1. Implications: stepped-care treatments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
7.2. Limitations and strengths . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
Role of funding sources . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
Conflict of interest . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0

Obsessive–compulsive disorder (OCD) is a common psychologi- 2. Cognitive–behavioral treatment for obsessive–compulsive disorder
cal condition that is characterized by the experience of obsessions
and compulsions (American Psychiatric Association, 2013). The Cognitive–behavioral models of OCD are largely based on the body
symptoms and clinical features of OCD have been documented for of research that demonstrates that intrusive thoughts are a universal
hundreds of years (Burton, 1989) and the disorder is characterized phenomenon which becomes problematic only when individuals mis-
by significant symptom heterogeneity. Obsessive–compulsive disor- interpret those intrusions as threatening (Rachman & de Silva, 1978).
der is a relatively common disorder, with a lifetime prevalence rate These cognitive–behavioral models hypothesize that symptoms of
of approximately 2–3% (Australian Bureau of Statistics, 2007; OCD are maintained by cognitive biases, engagement in compulsive be-
Kessler, Petukhova, Sampson, Zaslavsky, & Wittchen, 2012). Age of haviors, and avoidance of triggers (Rachman, 1997; Salkovskis, 1985,
onset appears to be bimodal, with a peak at mean ages of 1999). Best practice cognitive behavior therapy (CBT) addresses these
12.8 years and 24.9 years (Anholt et al., 2014). In adult samples the maintaining factors through a particular CBT technique, exposure and
disorder is more commonly seen in females (3.6% lifetime preva- response prevention (ERP). Specific cognitive interventions can some-
lence rate) than males (1.8% lifetime prevalence rate) (Kessler times be used in addition to ERP (Van Oppen et al., 1995). While the
et al., 2012), however males appear to be over-represented in child- exact mechanisms of this treatment are unknown it is hypothesized
hood presentations of OCD, with approximately one quarter having that ERP for OCD is effective because of the resultant 1) cognitive change
an onset of symptoms prior to age 10, in contrast to females who (correction of faulty assumptions); 2) habituation to the conditioned
are more likely to develop symptoms during adolescence (Ruscio, fear; or 3) increases in self-efficacy (Abramowitz, 2006).
Stein, Chiu, & Kessler, 2010). Symptoms of OCD tend to wax and In its contemporary administration ERP involves four components;
wane in response to life stressors, but rarely remit spontaneously 1) exposure in vivo, where the individual confronts feared stimuli in
without treatment (Pinto, Mancebo, Eisen, Pagano, & Rasmussen, real life; 2) exposure in imagination, where fears are confronted in
2006). The diagnosis of OCD is associated with considerable disabil- imagination; 3) response prevention, which involves instructing the in-
ity in various domains of functioning and individuals with OCD are dividual to cease any overt or covert behaviors that they would normal-
significantly more impaired than community samples (Eisen et al., ly do to eliminate their anxiety; and, 4) a processing component, which
2006). The extent of impairment in functioning and quality of life Foa (2010) describes as reviewing with the client what they have learnt
also appears positively correlated with the severity of symptoms from completing an exposure task. For example an individual with con-
(Eisen et al., 2006). tamination obsessions and cleaning/washing compulsions may be ex-
posed to touching progressively more ‘dirty’ objects in real life (in-
vivo exposure), may be instructed to imagine contracting a deadly dis-
1. Measurement of obsessive–compulsive symptoms ease (imaginal exposure), will be instructed to refrain from hand wash-
ing and other cleaning behaviors (response prevention), and may
The Yale–Brown Obsessive–Compulsive Scale (Y-BOCS) (Goodman discuss with the therapist after the exposure whether their fears
et al., 1989) is a 10-item measure of the severity of obsessive–compul- (i.e., of contracting a deadly disease) occurred (processing).
sive symptoms regardless of symptom presentation and is the gold- The initial literature on the efficacy of exposure based treatment for
standard outcome measure in the OCD literature. The Y-BOCS is usually OCD emerged in the late 1960s to early 1970s (Meyer, 1966; Rachman,
completed as a clinician-administered measure, however a self-report Hodgson, & Marks, 1971). Since this time traditional face-to-face expo-
version of the scale is also available, and responses on the self-report sure based treatments have consistently demonstrated clinical efficacy
Y-BOCS correlate highly with those on the clinician-administered scale (Eddy, Dutra, Bradley, & Westen, 2004; Gava et al., 2007; Olatunji,
(r = .76) (Steketee, Frost, & Bogart, 1996). The Y-BOCS demonstrates Davis, Powers, & Smits, 2013; Sánchez-Meca, Rosa-Alcázar,
good internal consistency in both clinician administered (range α = Iniesta-Sepúlveda, & Rosa-Alcázar, 2014). For instance, a recent meta-
.75–.87) (Anholt et al., 2010; Tolin et al., 2007) and self-report adminis- analysis of 16 randomized controlled trials (RCTs), spanning both child/
tration (range α = .73–0.92) (Ólafsson, Snorrason, & Smári, 2010; adolescent and adult samples, found a large effect size at post-treatment
Wootton, Dear, Johnston, Terides, & Titov, 2014). Total scores on the (g = 1.39) (Olatunji et al., 2013). Similar results were also found in a re-
measure range from 0 to 40 and a cut score of 16 is generally used to de- cent meta-analysis of pediatric OCD (Sánchez-Meca et al., 2014). While
termine a clinical level of symptoms. CBT treatments for OCD can differ slightly depending on the emphasis

Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
chology Review (2015), http://dx.doi.org/10.1016/j.cpr.2015.10.001
B.M. Wootton / Clinical Psychology Review xxx (2015) xxx–xxx 3

on ‘cognitive’ or ‘behavioral’ interventions, there does not appear to be Roberts, & Kane, 2013). Videoconferencing administered CBT has also
any differences in outcomes when primarily cognitive techniques are been used successfully in the treatment of OCD. While there are current-
used or when primarily behavioral techniques are used (Olatunji et al., ly no direct comparisons of vCBT and face-to-face CBT in the treatment
2013; Rosa-Alcázar, Sánchez-Meca, Gómez-Conesa, & Marín-Martínez, of OCD there are two RCTs that have compared vCBT with a waitlist con-
2008), however to date the number of studies that emphasize cognitive trol and both have found large between-group effect sizes at post-
techniques is far fewer in number than those that emphasize behavioral treatment (Storch et al., 2011; Vogel et al., 2014). Additional evidence
interventions (Olatunji et al., 2013). The literature also demonstrates on the efficacy of vCBT for OCD comes from uncontrolled studies
that CBT is effective regardless of baseline symptom severity, symptom (Goetter, Herbert, Forman, Yuen, & Thomas, 2014) and case series
subtype, gender, number of sessions, or comorbidity profile (Olatunji (Comer et al., 2014; Himle et al., 2006).
et al., 2013).
4.1.2. Telephone administered CBT (tCBT)
3. Barriers to accessing evidence-based treatment Telephone administered CBT interventions involve the client and
therapist interacting over the telephone. This mode of treatment has
Despite the availability of effective psychological treatments for OCD also been demonstrated to result in similar outcomes to standard face-
many individuals do not access traditional face-to-face evidence-based to-face treatments for a variety of conditions, including depression
treatments. Results from epidemiological studies indicate that approxi- (Mohr et al., 2012) and chronic pain (Carmody et al., 2013). Telephone
mately 60% of individuals with OCD remain untreated (Kohn, Saxena, administered CBT has also been used quite extensively in the OCD liter-
Levav, & Saraceno, 2004). Other research indicates that when individ- ature. Studies comparing tCBT with face-to-face CBT have emerged in
uals with OCD do access treatment they are often not provided with both adolescent (Turner et al., 2014) and adult (Lovell et al., 2006) sam-
an evidence-based treatment or do not receive a sufficient dose of ERP ples and demonstrate equivalent outcomes across methodologies. This
(Stobie, Taylor, Quigley, Ewing, & Salkovskis, 2007). Additionally, indi- approach has also been demonstrated to be effective for OCD in a num-
viduals with OCD often wait more than a decade to access treatment ber of uncontrolled trials (Taylor et al., 2003; Turner, Heyman, Futh, &
(Pinto et al., 2006). Multiple barriers exist to individuals seeking treat- Lovell, 2009) and case series (Lovell, Fullalove, Garvey, & Brooker,
ment for OCD including the cost of treatment, geographical isolation, 2000).
lack of access to trained clinicians, and stigma (Baer & Minichiello, These high intensity remote interventions are provided in a synchro-
2008; Belloch, Valle, Morillo, Carrió, & Cabedo, 2009; Goodwin, nous (i.e., real time) fashion and generally involve the same amount of
Koenen, Hellman, Guardino, & Struening, 2002; Marques et al., 2010). therapist contact that would typically be seen in face-to-face treatment,
The consequence of these barriers is that a large proportion of people thus while not overly cost saving, they do reduce barriers such as geo-
with OCD experience burden that could be averted. graphical isolation and lack of access to a trained clinician. There is
now growing evidence to suggest that high intensity remote treatment
4. Remote treatment for obsessive–compulsive disorder is just as effective as face-to-face treatment, however more controlled
trials are urgently needed.
Remote treatments are those that can be delivered without the ther-
apist physically being in the same room as the client, and can thus im-
prove access to evidence-based care. Remote treatments differ along 4.2. Low intensity remote treatments
multiple continua including whether they use technology to deliver re-
mote treatments in synchronous, or real time (high intensity remote in- Low intensity remote treatments involve patients systematically
terventions) or whether they involve brief and often asynchronous reading structured lessons, modules or information that present the
contact with a therapist (low intensity remote interventions). These in- same information and skills typically taught in face-to-face treatment
terventions are discussed in turn below. (Titov, 2007). The most commonly administered low intensity remote
treatments include computerized, internet- and bibliotherapy adminis-
4.1. High intensity remote treatments tered treatments. These low intensity interventions can be either
clinician-guided (i.e., some clinician contact is provided) or self-
High intensity remote treatments are those that use technology to guided (i.e., no clinician contact is provided), however it appears that
deliver a treatment that is analogous to traditional face-to-face treat- the provision of clinician support may result in improved outcomes
ment. The skills provided (i.e., psycho-education and ERP), and length (Johansson & Andersson, 2012; Marrs, 1995; Spek et al., 2007). When
of session (i.e., 60–90 min), are typically the same in high intensity re- low intensity treatments are guided the interaction between the client
mote treatment as in a traditional face-to-face treatment, however, and therapist is asynchronous (i.e., not in real time). The existing litera-
the patient and therapist have their session using technology aids. ture summarizing the use of these low intensity technologies in the
Using these technology aids the client and the therapist interact in treatment of OCD symptoms are outlined below.
real-time. Typical technologies that are used in high intensity remote
treatments include traditional or internet-based videoconferencing, or 4.2.1. Computerized CBT (cCBT)
the telephone. The existing literature summarizing the use of these Computerized treatments are those that consist of a treatment pro-
high intensity technologies in the treatment of OCD symptoms are gram that is usually loaded on to a single computer or are administered
outlined below. via a computerized device. Computerized treatments have been dem-
onstrated to be effective in the treatment of a number of disorders in-
4.1.1. Videoconferencing administered CBT (vCBT) cluding panic disorder and phobias (Marks, Kenwright, McDonough,
Videoconferencing delivered CBT involves the client and the thera- Whittaker, & Mataix-Cols, 2004) and anxiety and/or depression
pist interacting via a video-link, thus the client's non-verbal behavior (Proudfoot et al., 2003). The most commonly used computerized pro-
is able to be observed. The video-link may use traditional videoconfer- gram for the treatment of OCD is the Behavior Therapy (BT) Steps pro-
encing software, or may use web-based software. Videoconferencing gram. Individuals access the computer generated program via a touch
delivered CBT has demonstrated equivalent outcomes to face-to-face tone telephone rather than a computer, and they advance through
treatment for a variety of mental health conditions including depression each of the steps at their own pace (Greist et al., 2002). Several studies
(Nelson, Barnard, & Cain, 2003), post-traumatic stress disorder (Frueh have now demonstrated the efficacy of BT Steps in the treatment of OCD
et al., 2007), panic disorder (Bouchard et al., 2004) and a mixed sample (Bachofen et al., 1999; Greist et al., 2002; Greist et al., 1998; Kenwright,
of individuals with mood and anxiety disorders (Stubbings, Rees, Marks, Graham, Franses, & Mataix-Cols, 2005).

Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
chology Review (2015), http://dx.doi.org/10.1016/j.cpr.2015.10.001
4 B.M. Wootton / Clinical Psychology Review xxx (2015) xxx–xxx

4.2.2. Internet-administered CBT (iCBT) for diagnosis. For this reason the emphasis in this meta-analysis is on
Internet-delivered treatments are those that have materials that are ‘obsessive–compulsive symptoms’, rather than ‘obsessive–compulsive
accessible via the internet and are thus generally more flexible than com- disorder’.
puterized treatments. iCBT can be delivered as open access programs
(where anyone can access the program) or can be closed (where the pa- 5. Method
tient logs in with a secure username and password) (G. Andersson,
Carlbring, Ljótsson, & Hedman, 2013). Open access programs tend to re- 5.1. Search procedure
sult in lower effect sizes than closed program (G. Andersson et al., 2013)
and the discussion that follows relates only to closed iCBT programs. Relevant articles were identified through electronic databases
Results of a recent meta-analysis indicate that clinician-guided iCBT (Scopus, Medline and PsycINFO) through to December 4th 2014. The
is as effective as traditional face-to-face treatment for a variety of men- search terms used in the electronic database search included ‘obsessive
tal health conditions (Andersson, Cuijpers, Carlbring, Riper, & Hedman, compulsive or OCD’ AND ‘internet or telephone or videoconferenc* or
2014). For OCD, a number of recent studies have emerged demonstrat- bibliotherapy or computeri* or DVD or CD or distance or remote or
ing the efficacy of iCBT for OCD, with large effect sizes seen across three self-help’ AND ‘trial or RCT or randomi*ed’. The references of previously
RCTs (Andersson et al., 2012; Mahoney, Mackenzie, Williams, Smith, & completed reviews on the topic of remote treatment for OCD (Herbst
Andrews, 2014; Wootton, Dear, Johnston, Terides, & Titov, 2013) and et al., 2012; Lovell & Bee, 2011; Mataix-Cols & Marks, 2006a, 2006b;
5 open trials (E. Andersson et al., 2011; Lenhard et al., 2014; Wootton Tumur et al., 2007) were also reviewed.
et al., 2014; Wootton et al., 2011). Importantly, recent research suggests
that the effects of both clinician-guided and self-guided iCBT for OCD are
5.2. Study selection
sustained beyond 12-months post-treatment (Andersson, Steneby
et al., 2014; Wootton, Dear, Johnston, Terides, & Titov, 2015).
In order to be included, individual studies were required to: 1) be a
clinical trial with pooled data or a case series with calculable means
4.2.3. Bibliotherapy administered CBT (bCBT)
and standard deviations and an n ≥ five. Studies with a sample size less
Bibliotherapy is a remote treatment where the individual is provided
than five were excluded as they were deemed to likely lead to unreliable
with a printed workbook to conduct his or her own treatment. Similar to
results when data was pooled. 2) The study must also have specifically
other remote treatments, bibliotherapy involves teaching the individual
targeted OCD symptoms. 3) The study must include a remote treatment
the same skills and techniques taught in face-to-face treatment, howev-
(i.e., client located outside of the therapy office for bulk of treatment and
er, material is presented in a paper workbook rather than online or via a
no more than 120 min of in-office face-to-face treatment). This
computer (Kavanagh, Connolly, White, Kelly, & Parr, 2010). There is
timeframe was chosen as a cut point because greater contact would im-
considerable evidence to suggest that such self-help treatments are use-
pact the ability to label the treatment ‘remote’. 4) Studies must have used
ful in decreasing symptoms of depression and anxiety, particularly
the Yale–Brown Obsessive–Compulsive Scale (Y-BOCS) (Goodman et al.,
when the patient also receives remote support from a therapist
1989) (either clinician administered or self-report) as an outcome mea-
(Chung & Kwon, 2008; Cuijpers, Donker, Van Straten, Li, & Andersson,
sure with pre-treatment and post-treatment means and standard devia-
2010; Marrs, 1995; Nordin, Carlbring, Cuijpers, & Andersson, 2010;
tions available. 5) Studies must use CBT that incorporated a component
Scogin, Jamison, & Gochneaur, 1989). To date, one RCT has investigated
of ERP in the remote treatment; 6) must be published in English and de-
guided bCBT for OCD (Wootton et al., 2013) and another two RCTs have
scribe adequately the treatment methodology; and 7) must consist of
also demonstrated the efficacy of unguided bCBT (Moritz, Jelinek,
original data.
Hauschildt, & Naber, 2010; Tolin et al., 2007), with moderate to large ef-
Due to the small number of studies in this area both uncontrolled tri-
fect sizes seen. However, results are inconsistent with a more recent
als and RCTs were included as well as studies that investigated child/ad-
RCT finding only small effects from unguided bCBT (Vogel et al.,
olescent and adult samples. The most conservative outcomes from each
2014). Uncontrolled studies of bCBT for OCD demonstrate large effect
study were used (intention to treat (ITT) data was used when possible
sizes (Gilliam, Diefenbach, Whiting, & Tolin, 2010; Tolin, Diefenbach,
however completer data was used when ITT was unavailable). Studies
Maltby, & Hannan, 2005), indicating that bCBT may be a promising re-
were divided into type of remote treatment (vCBT, tCBT, cCBT, iCBT
mote treatment approach for OCD.
and bCBT) and were also divided into high and low intensity treatments
These low intensity remote interventions are provided in an asyn-
and self-guided and clinician-guided treatments.
chronous fashion and may be clinician-guided or self-guided. Due to
the reduced therapist time that is required, low intensity treatments
have the potential to provide considerable cost savings to healthcare 5.3. Data analysis
providers. These interventions are also important for those individuals
who avoid seeking treatment because of stigma or have a preference Effect size data was analyzed using Comprehensive Meta-Analysis
to self-manage symptoms. While further research is needed, low inten- Version 2.2 (Borenstein, Hedges, Higgins, & Rotherstein, 2011). All effect
sity treatments appear to be a promising treatment direction for indi- sizes were calculated on the Y-BOCS (Goodman et al., 1989). Within-
viduals with OCD, however more controlled trials are needed. group as well as between-group analyses were conducted using ran-
While several excellent reviews of remote treatment for OCD are dom effects models. Within-group effect sizes were calculated for
X 1 X 2
currently available (Herbst et al., 2012; Lovell & Bee, 2011; Cohen's d using the following formula SDdiff where X1 is the pre-
Mataix-Cols & Marks, 2006a, 2006b; Tumur, Kaltenthaler, Ferriter, Bev- treatment mean, X2 is the post-treatment mean and SDdiff is the SD of
erley, & Parry, 2007), they are now largely outdated, as a large amount the difference scores. The SDdiff was calculated with the following for-
pffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffi

of research in this area has been conducted in the last five years. Addi- SD12 þSD22 2rSD1 SD2
mula pffiffiffiffiffiffiffiffiffiffiffi where SD1 is the pre-treatment standard de-
tionally, while previous meta-analyses have been conducted investigat- 2ð1rÞ
ing remote treatments for other conditions (Bee et al., 2008) to date no viation, SD2 is the post-treatment standard deviation and r is the
studies have quantitatively defined outcomes of remote treatment spe- correlation between the pre-treatment and post-treatment scores
cifically for OCD by way of a meta-analysis. Therefore, the aim of the (Borenstein et al., 2011). However, because the correlations between
current study is to extend the literature and synthesize the research pre-treatment and post-treatment scores were not available a con-
on efficacy of remote treatment for obsessive–compulsive symptoms servative estimate of r = .70 was used, consistent with previous
using a meta-analytic approach. While all studies included in this meta-analyses (Glombiewski et al., 2010; Winkler, Dörsing, Rief,
meta-analysis were clinical samples, not all used a structured interview Shen, & Glombiewski, 2013). This score was then transformed to

Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
chology Review (2015), http://dx.doi.org/10.1016/j.cpr.2015.10.001
B.M. Wootton / Clinical Psychology Review xxx (2015) xxx–xxx 5

Hedges's g by multiplying it by correction J based on the following included in the analysis. The mean Y-BOCS score at baseline was 23.41
formula Jðdf Þ ¼ 1  4df31 (Borenstein et al., 2011). Consistent with pre- (SD = 2.02) indicating moderate symptoms. There were 516 partici-
vious meta-analyses (Glombiewski et al., 2010; Tolin, 2014; Winkler pants in the remote treatment conditions and 307 in the control condi-
et al., 2013) Hedges's g was interpreted in the following fashion: 0.2 a tions. Control conditions included face-to-face treatment, attention
small effect, 0.5 a medium effect, and 0.8 or greater a large effect. A pos- controls, relaxation training, and waitlist controls. Table 1 indicates all
itive g value indicates a decrease in symptoms of OCD and the larger the studies included in the analysis and the type of remote treatment that
value, the larger the effect. For within-group analyses an overall remote was provided. Half (50%) of the studies were RCTs and half (50%)
treatment effect size was calculated as well as an effect size for each were uncontrolled studies.
type of remote treatment (vCBT, tCBT, cCBT, iCBT and bCBT). Compari-
sons were also made between low-intensity treatment and high- 6.2. Within-group analyses
intensity treatment and self-guided treatment and clinician-guided
treatment. 6.2.1. Overall within-group effect size for remote treatment
Between-group analyses were conducted between the remote treat- Table 2 outlines the within-group effect sizes for each of the included
ment group and waitlist/attention control conditions and between re- studies. The pooled within-group mean effect size was large across all
mote treatment and face-to-face conditions. Consistent with the remote treatments from pre-treatment to post-treatment (k = 23;
recommendations of Higgins and Deeks (2008) for the between- g = 1.17; 95% CI: 0.91–1.43). A high level of heterogeneity across stud-
group comparisons the post-treatment scores of the remote treatment ies was indicated (I2 = 87.66). The Trim and Fill method indicated that
were compared with the post-treatment scores of the control group (ei- there was no publication bias (adjusted g = 1.03; 95% CI: 0.78–1.29).
ther waitlist/attention control or face-to-face treatment) rather than Using the one study removed method effect sizes remained unchanged
using change scores. For the between-group comparisons effect sizes (g = 1.17; 95% CI: 0.92–1.43).
were first calculated for Cohen's d according to the following formula Moderator analyses were conducted and the type of remote
X 1 X 2 treatment moderated outcome (Q4 = 28.70, p b .001). For each type
SDpooled where X1 is the post-treatment score for the remote treatment con-
of remote treatment within-group pooled effect sizes were large from
dition and X2 is the post-treatment score of the control condition. The pre-treatment to post-treatment for vCBT (k = 3; g = 1.68; 95% CI:
pffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffiffi
0.84–2.52; I2 = 69.02), tCBT (k = 3; g = 1.67; 95% CI: 1.41–1.93; I2 =
2 2
ðN 1 1ÞSD1 þðN2 1ÞSD2
SDpooled was calculated with the following formula N1 þN 2 2
where N1 is the sample size of the remote treatment group, N2 is the 0.00), iCBT (k = 8; g = 1.40; 95% CI: 1.06–1.74; I2 = 78.49) and bCBT
sample size of the control group, SD1 is the standard deviation of the re- (k = 3; g = 0.81; 95% CI: 0.06–1.56; I2 = 87.87). The effect size was
mote treatment group and SD2 is the standard deviation of the control moderate for cCBT (k = 6; g = 0.61; 95% CI: 0.29–0.93; I2 = 80.52).
group. Cohen's d was then converted to Hedges's g by multiplying it From pre-treatment to follow-up the pooled within-group effect
with correction J (calculated as above). For the between-group compari- size remained large across all remote treatments (k = 15; g = 1.22;
sons a positive g value indicates a superiority of the remote treatment 95% CI: 0.95–1.48). There continued to be high levels of heterogeneity
compared with other treatments and a negative g value indicates however (I2 = 83.19). Again, the Trim and Fill method indicated no
inferiority. publication bias (adjusted g = 1.09; 95% CI: 0.84–1.34). Using the one
Homogeneity of effect sizes was evaluated using the I2 statistic. An I2 study removed method effect sizes remained large (g = 1.06; 95% CI:
value of 25% is generally considered low heterogeneity among studies, 0.96–1.17).
50% as moderate and 75% as high (Higgins, Thompson, Deeks, & Moderator analyses were conducted and the type of remote treat-
Altman, 2003). Where there was a moderate level of heterogeneity ment moderated outcome (Q4 = 50.84, p b .001). Pooled within-
(i.e., ≥50%) and sample size allowed for it, post-hoc moderator analyses group effect sizes remained large at follow-up for vCBT (k = 2; g =
were conducted. Moderators included type of remote treatment 1.57; 95% CI: 1.13–2.02; I2 = 0.00), tCBT (k = 3; g = 1.61; 95% CI:
(i.e., iCBT, bCBT, cCBT, vCBT, or tCBT), intensity of treatment (i.e., low in- 1.36–1.87; I2 = 0.00), iCBT (k = 7; g = 1.21; 95% CI: 0.93–1.50; I2 =
tensity vs. high intensity), and level of therapist guidance in the treat- 69.40) and bCBT (k = 2; g = 0.80; 95% CI: 0.06–1.54; I2 = 85.33).
ment (i.e., self-guided or clinician-guided). Sensitivity analyses were There was only one study of cCBT at follow-up and the effect size was
also conducted to investigate the impact of each study on the combined small (k = 1; g = 0.41; 95% CI: 0.16–0.66; I2 = 0.00).
effect, using the ‘one-study removed’ method, which systematically
removes each study to determine the change in overall effect size. Pub- 6.2.2. Low intensity vs. high intensity remote treatment
lication bias was assessed using Duval and Tweedie's Trim and Fill Clinician-guided low intensity interventions (which utilize a much
method (Duval & Tweedie, 2000), which ‘trims’ the most extreme lower level of clinician contact than standard CBT) were compared
small positive studies from the analysis and ‘fills’ these studies with a with high intensity remote treatments (which utilize a similar amount
mirror image resulting in an unbiased estimate of the effect size of clinician contact to standard CBT). Pre-treatment to post-treatment
(Borenstein et al., 2011). Due to the preliminary nature of this study pooled within-group effect sizes were large for the low intensity treat-
an analysis of data quality was not performed. ments (k = 10; g = 1.36; 95% CI: 1.00–1.72), with high levels of hetero-
geneity (I2 = 82.59). High intensity treatments also resulted in a
decrease in symptoms of a large magnitude (k = 6; g = 1.64; 95% CI:
6. Results 1.33–1.95), with low levels of heterogeneity (I2 = 40.60). A significant
difference between low intensity and high intensity treatments was
Fig. 1 outlines the study selection process. The search yielded 256 ar- not seen (Q1 = 1.39, p = .24). The low intensity group demonstrated
ticles. The abstracts were reviewed and 209 were excluded, resulting in a high level of heterogeneity, thus post-hoc moderator analyses were
47 studies. These 47 studies were reviewed in full against the inclusion conducted. The type of treatment moderated outcome (Q2 = 13.26,
and exclusion criteria and 29 were excluded, resulting in 18 included p = .001; iCBT: k = 6; g = 1.60; 95% CI: 1.31–1.90; I2 = 54.08; bCBT:
studies in the meta-analysis. Study eligibility was determined by the au- k = 1; g = 1.65; 95% CI: 1.13–2.17, I2 = 0.00; cCBT: k = 3; g = 0.68;
thor using a comprehensive coding sheet. 95% CI: 0.25–1.11; I2 = 62.03). The results at follow-up were similar
with large pooled within-group effect sizes for low intensity treatment
6.1. Study characteristics (k = 6; g = 1.36; 95% CI: 1.14–1.57) with low levels of heterogeneity
(I2 = 25.91). High intensity treatments also demonstrated large
In total 823 individuals (mean age 31.20 (SD = 10.36), 56.2% fe- within-group effect sizes at follow-up (k = 5; g = 1.60; 95% CI: 1.38–
male) across 18 studies (with 23 remote treatment conditions) were 1.82), with low levels of heterogeneity (I2 = 0.00). At follow-up there

Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
chology Review (2015), http://dx.doi.org/10.1016/j.cpr.2015.10.001
6 B.M. Wootton / Clinical Psychology Review xxx (2015) xxx–xxx

Fig. 1. Study flow chart.

was no significant difference between the low intensity and high From pre-treatment to follow-up the results were the same with
intensity groups (Q1 = 2.48, p = .12). large pooled within group effect sizes for clinician-guided remote treat-
ments (k = 6; g = 1.36; 95% CI: 1.14–1.57) with low levels of heteroge-
6.2.3. Self-guided vs clinician-guided low intensity treatments neity (I2 = 25.91). The self-guided treatment effect size remained
Low intensity remote treatments can be provided in either a self- moderate (k = 4; g = 0.58; 95% CI: 0.36–0.80) with low levels of het-
guided or clinician-guided fashion. Treatments were deemed as self- erogeneity (I2 = 43.70). Again, this was a significant difference favoring
guided when they did not utilize clinician contact during the treatment the high intensity group (Q1 = 25.09, p b .001).
and guided when some clinician contact was provided during the treat-
ment. Pre-treatment to post-treatment pooled within-group effect sizes 6.3. Between-group analyses
were large for the clinician-guided group (k = 10; g = 1.36; 95% CI:
1.00–1.72) with high levels of heterogeneity (I2 = 82.59). For the self- 6.3.1. Remote treatment vs. control
guided group moderate effects were seen (k = 7; g = 0.58; 95% CI: A total of five studies (7 comparisons) compared a remote treatment
0.32–0.84) also with high levels of heterogeneity (I2 = 77.74). This to a waitlist control or attentional control group in a randomized con-
was a significant difference favoring the clinician-guided group (Q1 = trolled design. Between-group analyses indicated a large pooled effect
11.68, p b .001). size at post-treatment (k = 7; g = 1.06; 95% CI: 0.68–1.45) favoring
Both clinician-guided and self-guided treatments demonstrated the remote treatments (Q6 = 15.55, p = .02). Table 3 outlines the
moderate levels of heterogeneity (I2 ≥ 50%) thus post-hoc moderator between-group effect sizes at post-treatment for each of the included
analyses were conducted. For the guided treatment pre–post-treatment studies. Heterogeneity was moderate (I2 = 61.42), suggesting differ-
effect size was moderated by type of treatment (Q2 = 13.26, p = .001), ences in outcome across studies. The Trim and Fill procedure indicated
with those using iCBT (k = 6; g = 1.60; 95% CI: 1.31–1.90; I2 = 54.08) no evidence of publication bias (adjusted g = 0.94; 95% CI: 0.52–
and bCBT (k = 1; g = 1.65; 95% CI: 1.13–2.17, I2 = 0.00) methodologies 1.37). The one study removed method also indicated no change to the
outperforming those using cCBT (k = 3; g = 0.68; 95% CI: 0.25–1.11; effect size (g = 1.06; 95% CI: 0.68–1.45). Two of the seven comparisons
I2 = 62.03) methodologies. For the self-guided treatments pre–post- (29%) were iCBT interventions, 1/7 (14%) were cCBT, 2/7 (29%) were
treatment effect size was not moderated by type of treatment (Q2 = vCBT, and 2/7 (29%) were bCBT. Five of the seven comparisons (71%)
3.49, p = .18; iCBT: k = 2; g = 0.82; 95% CI: 0.55–1.09; I2 = 12.67; were low intensity treatments and 2/7 (29%) were high intensity
bCBT: k = 2; g = 0.44; 95% CI: 0.15–0.74; I2 = 0.00; cCBT: k = 3; treatments. Two out of the seven (29%) comparisons were self-guided
g = 0.54; 95% CI: 0.04–1.04; I2 = 89.91). and 5/7 (71%) were clinician guided. Post-hoc moderator analyses

Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
chology Review (2015), http://dx.doi.org/10.1016/j.cpr.2015.10.001
B.M. Wootton / Clinical Psychology Review xxx (2015) xxx–xxx 7

Table 1
Characteristics of included studies.

Study Country Study Treatment n Amount of remote Mean baseline Mean age % Female Longest Population
type contact (min) Y-BOCS score (years) follow-up
period

E. Andersson et al. (2011) Sweden U iCBT 24 92.0 20.00 39.0 65.0 None Adult
iCBT 50 129.0 21.42 33.0 66.0 4-Month
Andersson et al. (2012) Sweden RCT Adult
Attention control 51 17.0 20.80 35.0 66.7 None
Bachofen et al. (1999) UK U cCBT 21 5.0 25.00 31.0 43.5 None Adult
Comer et al. (2014) USA U vCBT 5 Not reported 24.20 7.0 40.0 None Child
Greist et al. (1998) Multiple U cCBT 40 Not reported 23.6 34.9 47.5 ~22 weeks Adult
cCBT 55 Not reported 24.6 None
Adolescent
Greist et al. (2002) Multiple RCT Relaxation 66 Not reported 25.8 39.0 42.0 None
and adult
Face-to-face 55 660 25.2 None
cCBT (scheduled) 20 76 26.5 None
Kenwright et al. (2005) UK RCT 40.0 52.3 Not stated
cCBT (requested) 16 16 24.5 None
Lenhard et al. (2014) Sweden U iCBT 21 233.8 21.33 14.4 61.9 6-Month Adolescent
tCBT 36 360 25.9 33.4 56.0 6-Month Adolescent
Lovell et al. (2006) UK RCT
Face to face 36 600 25.5 30.4 61.0 6-Month and adult
Marks et al. (2003) UK U cCBT 9 Not reported 23.2 Not reported Not reported None Not stated
vCBT 16 ~840 21.27 11.00 37.0 3-Month Child and
Storch et al. (2011) USA RCT
Waitlist control 15 N/A 25.38 11.20 40.00 None adolescent
bCBT 20 Not reported 22.70 40.30 75.0 6-Month
Tolin et al. (2007) USA RCT Adult
Face to face 21 Not reported 23.95 34.10 52.4 6-Month
Turner et al. (2009) UK U tCBT 10 Not reported 27.00 Not reported 20.0 12-Month Adolescent
tCBT 36 Not reported 25.64 14.19 44.5 12-Month Child and
Turner et al. (2014) UK RCT
Face to face 36 Not reported 24.11 14.50 47.2 12-Month adolescent
vCBT 10 Varied 24.2 28.8 60.0 3-Month
Vogel et al. (2014) Norway RCT Waitlist control 10 N/A 23.4 40.7 70.0 None Not stated
bCBT 10 0 24.1 29.8 50.0 None
Wootton et al. (2011) Australia U iCBT 21 86.1 20.90 35.18 59.0 3-Month Adult
iCBT 15 86.63 23.53 39.93 93.3 3-Month
RCT bCBT 20 102.73 21.80 35.55 70.0 3-Month
Wootton et al. (2013) Australia Adult
Waitlist control 17 N/A 21.06 38.58 64.7 None
U iCBT 17 57.06 19.87 38.58 64.7 3-Month
U iCBT 16 0 21.81 32.62 87.5 3-Month Adult
Wootton et al. (2014) Australia
U iCBT 28 0 20.79 35.90 67.9 3-Month Adult

Note. RCT = randomized controlled trial and U = uncontrolled trial. tCBT = telephone administered CBT; bCBT = bibliotherapy administered CBT; vCBT = videoconferencing adminis-
tered CBT; cCBT = computerized CBT; iCBT = internet administered CBT.

were not conducted due to the small sample size. There were no face-to-face treatment for OCD, where effect sizes of approximately
between-group comparisons available at follow-up. 1.1 are generally seen (Eddy et al., 2004; Rosa-Alcázar et al., 2008).
When looking at the few studies (k = 4) that have compared a re-
6.3.2. Remote treatment vs. face-to-face treatment mote treatment to standard best practice CBT face-to-face treatment
Table 4 outlines the between-group effect sizes at post-treatment there do not appear to be any meaningful differences in outcome
and follow-up for each of these studies. A total of four studies compared (g = − 0.21; 95% CI: − 0.43–0.02), due to the small effect and confi-
a remote CBT treatment to face-to-face CBT treatment at post- dence interval crossing zero. While preliminary, this suggests that re-
treatment. Between-group analyses indicated a small pooled effect mote treatment may be as effective as best practice face-to-face
size at post-treatment between the remote and face-to-face treatment treatment. However, it is important to note that across each of these
groups (k = 4; g = −0.21; 95% CI: −0.43–0.02). The Trim and Fill pro- studies the effect size differences are in the favor of face-to-face treat-
cedure indicated no evidence of publication bias (adjusted g = −0.20; ment and further research is required to elucidate the differences in out-
95% CI: −0.43–0.02). The one study removed method also indicated no come between different types of remote treatment and face-to-face
change to the effect size (g = −0.21; 95% CI: −0.43–0.02). There were treatment. Overall, this finding is consistent with a previous meta-
low levels of heterogeneity among the studies (I2 = 0.00). Similar re- analysis of remote treatment for anxiety disorders that found a small
sults were also found at follow-up (k = 3; g = − 0.28; 95% CI: between-group effect size between remote treatment and face-to-face
−0.58–0.01; I2 = 0.00). The Trim and Fill procedure indicated no evi- treatment (d = − 0.11 (−0.60–0.38); Bee et al., 2008) favoring face-
dence of publication bias (adjusted g = −0.28; 95% CI: − 0.57–0.00). to-face treatment. However, due to the small number of RCTs that
The one study removed method also indicated no change to the effect have been conducted to date that compare face-to-face and remote
size (g = −0.28; 95% CI: −0.58–0.00). treatment in the OCD literature this question requires further investiga-
tion in the future and these results should be considered preliminary.
7. Discussion This is particularly important since the included studies in the current
meta-analysis did not cover the full spectrum of remote treatments
The aim of this study was to extend the existing reviews of remote for OCD. For instance, currently, no RCTs have been conducted to date
treatment for OCD and to provide an evaluation of the efficacy of remote that compare iCBT or vCBT with face-to-face treatment and thus are im-
treatment for OCD using a meta-analytic approach. Because of the small portant avenues for future research.
amount of research conducted in this area to date both controlled and When investigated individually, almost all types of remote treat-
uncontrolled studies were included the analysis. Overall, the results of ment (vCBT, tCBT, iCBT and bCBT) for OCD resulted in large pooled effect
this meta-analysis indicate that remote treatment for OCD is an effica- sizes at post-treatment (range: g = 0.81–1.68) and these results were
cious and promising treatment delivery with large within-group effect generally maintained at follow-up (range: g = 0.80–1.61). The excep-
sizes seen when all remote treatments are pooled together (g = 1.17). tion was cCBT, which demonstrated moderate effect sizes at post-
This pooled effect size is within the same range as meta-analyses of treatment (g = 0.61) and small effect sizes at follow-up (g = 0.41). It

Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
chology Review (2015), http://dx.doi.org/10.1016/j.cpr.2015.10.001
8 B.M. Wootton / Clinical Psychology Review xxx (2015) xxx–xxx

Table 2
Within-group effect sizes from pre-treatment to post-treatment and pre-treatment to follow-up.

Study Type of remote treatment Pre-treatment to Weight of Pre-treatment to Weight of included study
post-treatment included study follow-up

g 95% CI g 95% CI

E. Andersson et al. (2011) iCBT 1.47 1.01–1.92 4.50 – – –


E. Andersson et al. (2012) iCBT 1.47 1.16–1.78 4.88 1.30 1.01–1.59 7.64
Bachofen et al. (1999) cCBT 0.71 0.34–1.08 4.73 – – –
Comer et al. (2014) vCBT 1.21 0.32–2.10 3.18 – – –
Greist et al. (1998) cCBT 0.09 −0.15–0.33 5.03 0.41 0.16–0.66 7.84
Greist et al. (2002) cCBT 0.84 0.60–1.07 5.03 – – –
Kenwright et al. (2005) cCBT 0.33 −0.06–0.72 4.68 – – –
Kenwright et al. (2005) cCBT 0.73 0.35–1.11 4.70 – – –
Lenhard et al. (2014) iCBT 2.22 1.60–2.83 4.01 2.02 1.44–2.60 6.00
Lovell et al. (2006) tCBT 1.87 1.45–2.29 4.60 1.62 1.23–2.00 7.15
Marks et al. (2003) cCBT 1.18 0.52–1.84 3.88 – – –
Storch et al. (2011) vCBT 1.31 0.80–1.83 4.31 1.49 0.94–2.04 6.16
Tolin et al. (2007) bCBT 0.55 0.19–0.91 4.75 0.43 0.08–0.79 7.31
Turner et al. (2009) tCBT 1.67 0.93–2.41 3.62 1.57 0.85–2.28 5.20
Turner et al. (2014) tCBT 1.51 1.14–1.88 4.73 1.62 1.24–2.00 7.15
Vogel et al. (2014) vCBT 2.77 1.71–3.82 2.75 1.73 0.97–2.49 4.96
Vogel et al. (2014) bCBT 0.26 −0.23–0.75 4.40 – – –
Wootton et al. (2011) iCBT 1.59 1.10–2.09 4.37 1.24 0.80–1.68 6.82
Wootton et al. (2013) bCBT 1.65 1.13–2.17 4.30 1.19 0.74–1.63 6.81
Wootton et al. (2013) iCBT 2.15 1.44–2.87 3.71 1.17 0.66–1.68 6.42
Wootton et al. (2013) iCBT 1.10 0.60–1.59 4.38 1.49 0.92–2.06 6.05
Wootton et al. (2014) iCBT 0.64 0.23–1.06 4.61 0.73 0.30–1.15 6.91
Wootton et al. (2014) iCBT 0.93 0.61–1.24 4.87 0.82 0.51–1.13 7.57
Mean 1.17 0.92–1.43 1.22 0.95–1.48

Note. tCBT = telephone administered CBT; bCBT = bibliotherapy administered CBT; vCBT = videoconferencing administered CBT; cCBT = computerized CBT; iCBT = internet adminis-
tered CBT.

is not clear what might account for the lower effect size in cCBT treat- remote treatments (Palmqvist, Carlbring, & Andersson, 2007). The re-
ments. It is possible that the lower effect size reflects the intervention sults from this meta-analysis were generally consistent with this and in-
(all used the same program) rather than the treatment modality. How- dicated that while both low intensity and high intensity treatments
ever this may also be an artifact of the small number of studies, and fur- result in a decrease in symptoms of a large magnitude at post-
ther research is required. treatment (g = 1.36 and g = 1.64 respectively) and follow-up (g =
Generally acceptable levels of heterogeneity were seen across each 1.36 and g = 1.60 respectively), the effect size in the high intensity
type of treatment, and where heterogeneity was high post-hoc moder- group are larger than the low intensity treatment, however this differ-
ator analyses indicated that those studies that were clinician-guided ence in effect size was not significant. The high intensity treatments
(i.e., contained some amount of clinician contact) performed better demonstrated low levels of heterogeneity suggesting that results are
than those studies that were self-guided (i.e., contained no therapist generally robust across studies. Moderate levels of heterogeneity were
support). This finding is consistent with other studies that have found demonstrated in the low intensity treatment suggesting that results
that clinician-guided remote treatments are more effective than self- are not uniform across studies. Moderator analyses indicated that type
guided treatments across various mental health conditions (Marrs, of treatment may be important, however further research is required
1995; Spek et al., 2007). However recent research has indicated that to elucidate possible moderators of outcome in clinician-guided low in-
self-guided low intensity treatments can be enhanced with the use of tensity treatment.
automated email reminders and prompts (Titov et al., 2013) and further The comparisons of remote treatment to a control condition indicate
research is required to ascertain if self-guided treatments with prompts that remote treatments, regardless of what kind of methodology is de-
and reminders are as effective as guided low intensity interventions. livered, is far more effective than no treatment. The current study
Some authors argue that there may be a linear relationship between found an effect size of g = 1.06 at post-treatment between remote treat-
the amount of therapist time spent with a patient and outcome in ments and control conditions. This finding is consistent with a previous

Table 3
Between-group effect sizes comparing remote CBT to no treatment, attentional control, or relaxation at post-treatment.

Study Type of remote treatment Type of control group Post-treatment Weight of included study

g 95% CI

Remote treatment vs. control


E. Andersson et al. (2012) iCBT Attention control 1.11 0.69–1.53 19.58
Greist et al. (2002) cCBT Relaxation 0.73 0.36–1.10 20.66
Storch et al. (2011) vCBT Waitlist control 0.76 0.05–1.48 13.66
Vogel et al. (2014) bCBT Waitlist control 0.13 −0.71–0.97 11.56
Vogel et al. (2014) vCBT Waitlist control 2.37 1.26–3.49 8.16
Wootton et al. (2013) bCBT Waitlist control 1.37 0.66–2.08 13.78
Wootton et al. (2013) iCBT Waitlist control 1.53 0.76–2.31 12.60
Mean – – 1.06 0.68–1.45 –

Note. tCBT = telephone administered CBT; bCBT = bibliotherapy administered CBT; vCBT = videoconferencing administered CBT; cCBT = computerized CBT; iCBT = internet adminis-
tered CBT. The attention control condition in E. Andersson et al. (2012) was also provided remotely and included non-directive supportive counseling. The format of the relaxation con-
dition in Greist et al. (2002) was not stated. The waitlist control conditions received no further contact until the post-treatment period.

Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
chology Review (2015), http://dx.doi.org/10.1016/j.cpr.2015.10.001
B.M. Wootton / Clinical Psychology Review xxx (2015) xxx–xxx 9

Table 4
Between-group effect sizes comparing remote CBT to face-to-face CBT.

Study Remote Face-to-face treatment Post-treatment Weight of included Follow-up Weight of


treatment study included study

Format Intensity Number of Total therapist g 95% CI g 95% CI


sessions contact

Greist et al. (2002) cCBT Low 11 11 h −0.21 −0.58–0.17 37.59 – – –


Lovell et al. (2006) tCBT High 10 10 h −0.08 −0.55–0.39 23.53 −0.11 −0.59–0.37 36.70
Tolin et al. (2007) bCBT Low 15 ns −0.47 −1.08–0.14 14.04 −0.46 −1.07–0.15 23.03
Turner et al. (2014) tCBT High 14 ns −0.17 −0.63–0.29 24.84 −0.34 −0.80–0.12 40.26
Mean −0.21 −0.43–0.02 −0.28 −0.58–0.00

Note. tCBT = telephone administered CBT; bCBT = bibliotherapy administered CBT; vCBT = videoconferencing administered CBT; cCBT = computerized CBT; iCBT = internet adminis-
tered CBT. ns = not stated.

meta-analysis that investigated remote treatments for anxiety more and uncontrolled trials were included in analyses and as the field
generally, which also found a large between-group effect size between emerges a greater emphasis should be placed on more internally valid
remote treatment and control (d = 1.15 (0.81–1.49); Bee et al., 2008), RCTs in order to evaluate the efficacy of remote treatments for OCD. Sec-
favoring the remote treatment condition. While the current results are ondly, not all studies used a diagnostic assessment to ensure a diagnosis
promising, the included studies did demonstrate moderate levels of het- of OCD prior to study entry. Thirdly, this study combined both child/ad-
erogeneity and moderator analyses were not conducted due to the olescent and adult samples and these groups may respond differentially
small sample size. It is important for future research to focus on deter- to remote treatments. Fourthly, a single author extracted the data and
mining potential moderators such as treatment population (adult ver- future research may benefit from the utilization of a second coder,
sus child/adolescent), type of remote treatment, severity of symptoms, with an additional assessment of inter-rater reliability. Finally, unpub-
and type of symptoms once a greater number of RCTs emerge in this lished data in this area may exist which may overturn the results of
field. this study and should be addressed in future studies in this area. Ad-
dressing these limitations in future meta-analyses is important as a
7.1. Implications: stepped-care treatments greater number of studies in this field emerge.
The major strength of this paper is that it is the first to quantify the
Overall, remote treatment appears to be efficacious, with similar outcomes of remote treatments for OCD using a meta-analytic ap-
outcomes to those seen in face-to-face treatment. It appears that the proach. In addition, the study compares various forms of remote treat-
amount of therapist contact may be a moderating factor and while ments (vCBT, tCBT, cCBT, iCBT, and bCBT), and also compares low
both low intensity and high intensity treatments resulted in a decrease intensity and high intensity treatments, and guided and self-guided
in symptoms of a large magnitude, the effect size in high intensity treat- treatments, rather than treating all remote treatment as equally effec-
ments was larger. These finding have important implications for treat- tive. The results of this meta-analysis may help to explore further
ment dissemination, and in particular, for the development of remote novel methods of service delivery for OCD, in particular, remote stepped
stepped-care approaches in the treatment of OCD. care treatments for OCD.
Stepped-care treatments provide the patient with the lowest inten-
sity (and most cost effective) option before moving up to more inten- Role of funding sources
sive (and costly) treatments. Stepped-care treatments are commonly
recommended in the OCD literature (Lovell & Richards, 2000; This was an unfunded study and no funding sources have been
Mataix-Cols & Marks, 2006b; National Institute for Health and Clinical omitted.
Excellence, 2005), have been demonstrated to be effective in the treat-
ment of OCD (Gilliam et al., 2010; Tolin et al., 2005), and have been Contributors
shown to result in significantly reduced costs (Tolin, Diefenbach, &
Gilliam, 2011). However, a limitation of these traditional stepped-care This is a single author manuscript and I confirm that there are no
models is that they do not take into account geographical and other bar- other persons who satisfied the criteria for authorship that are not
riers that impede an individual's ability to access traditional face-to-face listed. The author conducted literature searches, collected and analyzed
treatments (Baer & Minichiello, 2008; Belloch et al., 2009; Goodwin the data, and wrote the manuscript.
et al., 2002; Marques et al., 2010). Thus, many individuals are not able
to ‘step up’ to the more intensive levels of care (such as face-to-face out- Conflict of interest
patient or inpatient services) if they have not benefitted from a low in-
tensity treatment. According to the findings of this meta-analysis an There are no known conflicts of interest associated with this publica-
entirely remote stepped-care treatment may be possible where low in- tion and there has been no significant financial support for this work
tensity remote treatments (such as iCBT or bCBT) are offered as a first that could have influenced its outcome.
step in a stepped-care treatment for OCD, followed by higher intensity
remote treatments (such as vCBT or tCBT) if required. This will enable Acknowledgments
individuals who are unable to access face-to-face treatment to obtain
highly effective treatment for their symptoms. An evaluation of such a None.
remote stepped-care design would be beneficial in future research
due to its important implications for service delivery. References

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Please cite this article as: Wootton, B.M., Remote cognitive–behavior therapy for obsessive–compulsive symptoms: A meta-analysis, Clinical Psy-
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