Printed Pages: 01 ‘Sub Code:BP-701T Paper Id; 231161 Roll Na. B, PHARM, (VIL SEMESTER) THEORY EXAMINATION 2022-23 INSTRUMENTAL METHODS OF ANALYSIS Time: 3 Hours Total Marks: 75 Note: Attempt all Sections SECTION A 1, Attempt aff questions in brief. 10x2=20 (8) Give principle of UV spectroscopy (b) Describe quenching with examples. (©) Explain principle of Flame Photometry. (4) What are various methods for preparation of TLC plates? (©) Give significance of Fermi Resonance. (Define Chromophores with examples, (2) Givenames of detectors used in HPLC (h) Describe principle of Affinity Chromatography. (i) —_Explain applications of Nephelometry. i) Discuss factors affecting Vibrational frequency in IR spectroscopy. SECTION B 2. Attempt any fvo parts of the following: 2x10=20 (a) Discuss theory jolved in IR Spectroscopy. Explain instrumentation of IR spectrophotometer (b) Describe theory, principle, instrumentation and applications of Gas Chromatography (©) Differentiate between Atomic absorption and atomic emission. Describe various. applications interferences involved in Atomic Absorption Spectroscopy SECTION C 3. Attempt any five parts of the following: 7x5=35 (a) Give theory of Gel Electrophoresis, Explainfactors affecting electrophoretic mobility (b) What is Finger Print region? Explainfundamental modes of vibrations in poly: atomic molecules. (c) Explain applications of Spectrofluorometry (d) Describe mechanism of ion exchange process in Ion Exchange Chromatography (©) Explain Isoeratic and Gradient Elution in HPLC. () Discuss significance of derivatisation in Gas Chromatography (g) Describe spectral shifts and sol ent effect on absorption spectra in UV Spectroscopy https:/Mww.aktuonline.comy201 Sub Sse BP702T 231330 Roll No. [| B PHARM (SEM VIl) THEORY EXAMINATION 2022-23 INDUSTRIAL PHARMACY II Time: 3 Hours Total Marks: 75 Note: (a) (b) (©) @ () () (hy wo @ Pa (a) (b) (© 3 (b) © @ © (g) Attempt all Sections. If require any missing data: then choose suitably SECTION A Attempt all questions in brief. 10 x2=20 Define Pilot Plant. Describe Platform Technology Define Confidentialiy Agreement. Discuss thepractical aspects of Commercialization. Explain Drug metabolism and Toxicology Quote the reponsibilities of Regulatory affairs professionals. Define ISO 14000. Write a short note on GLP. Define CDSCO. Define Ceniificate of Pharmaceutical Product (COPP). SECTION B Attempt any vo parts of the following: 2x10=20 What are SUPAC Guidelines. Explain the SUPAC guidelines for immediate release dosage forms, Outline Quality Risk Management. Discuss the various risk management tools and methodologies. Explain : (i) Total Quatity Management (ii) Outof Specification (ii) Change Control (ix) 180.9000 series SECTION C Attempt any five parts of the following: 5x7=35 Describe the pilot plant scale up considerations for solid dosage forms. Discuss the significance of space requirements and raw materials in pilot plant set up. Explain various Technology Transfer agencies in India. Outline Validation and Qualification, Write a short note on Analytical Method Transfer. Summarize Investigational Brochure. What do you understand by IND. Describe Six Sigma Concepts Explain the organization structure and responsibilities of CDSCO. https /www.aktuonline.comPrinted Pages: 01 ‘Sub Code:BP703T. Paper Id: | 231834 Roll No. I I B PHARM (SEM VII) THEORY EXAMINATION 2022-23 PHARMACY PRACTICE Time: 3 Hours Total Marks: 75 Note: 1. Attempt all Sections. SECTION A 1, Attempt af questions in brief. 10x2=20 (a) Define ADR. (>) Explain Therapeutic drug monitoring (c)_ Gives some sources of drug information in Indian background. (4) Structure of retail and whole sale drug store. (@) Write the code of ethics of community pharmacy (0) What isvard round participation? (g) What is drug store management? (h) Write the concept of clinical pharmacy (i) Gives the various types of inventory control process? (i) Gives the objectives of patient counseling. SECTION B 2, Attempt any neo parts of the following: 2x10=20 (a) Classify hospital and explain the organization structure of a hospital highlighting its staff requirements. (b) Discuss various type of drug distribution system in a hospital for In and Out patient. (©) Write the role of pharmacist in education and tanning program in the hospital and also explain the intemal and extemal training program in hospital SECTION C 3. Attempt any five parts of the following: 7x8=38 (a) Discuss and defined the investigational of new drug. (6) Write a note on drug therapy monitoring and OTC Medication. (©) Defined therapeutic drug monitoring and gives its factors to be considered and what are the roles in Indian scenario. () Define budget and what are the steps involving in preparing a budget? Explain briefly (e) Explain the principle involved in the methods of inventory control ABC. VED. EOQ. (D.— Write the different clinical laboratory test for blood (g) Give the objective, need, advantage of hospital formulary https:/Mwww.aktuonline.comyPrinted Pages:01 ‘Sub Code: BP704T Paper Id: Rot No. (TT TTT TTT) B PHARM (SEM VII) THEORY EXAMINATION 2022-23 NOVEL DRUG DELIVERY SYSTEM (NDDS) Time: 3 Hours Total Marks: 75 Note: Attempt all Sections. If require any missing data: then choose suitably SECTION A 1, Attempt af questions in brief. 10x2=20 (@) Define the term Microencpsulation and Microcapsules (6) Explain the functions of the various structural components of Liposomes. (©) Mention the plications of Monoclonal antibodies on targeted drug delivery (4) Define the term “permeation enhancers” with examples. (©) Mentiorbasie components of Transdermal drug delivery systems. (0 Eplain Spray drying/spray congealing method. () Mention the advantages anddisad vantages of Buccal drug delivery system (b) Define Niosomes and Nangarticles. (@) Define Hydrodynamic pressure activate DDS, @ Mention different factors affecting transmucosal permeability, SECTION B 2 Attempt any wo parts of the following: 2x10=20 (a) Explain the Different formulation approaches of Transdermal Drug Delivery Systems, (b) Discuss implantable drug delivery system and explain in detail osmotic pump. (©) Describe the various proaches for designing controlled release formulations. SECTION C 3. Attempt any five parts of the following: Sx7=35 (a) Explain in brief the various methods to overcome ocular barriers for effective drug delivery. (b) Discuss the Development and applications of IUDs in pharmaceutical drug delivery. (©) Mention the various formulation approaches for gastro-retentive drug delivery systems, Discuss any one method. (4) Define targeted drug delivery system and explain the various drug targeting approaches, (e) Discuss briefly Nebulizer and Metered dose Inhalers. (4) Define and classify polymers and explain applications of polymers. (g) Explain the significance and limitations of naso-pulmonary drug delivery systems. https:/www.aktuoniine.conyUOMO a A Roll No: BPHARM (SEM VII) THEORY EXAMINATION 2021-22 INSTRUMENTAL METHODS OF ANALYSIS Time: 3 Hours Total Marks: 75 Note: 1. Attempt all Sections. If require any missing data; then choose suitably. | SECTIONA 1. Attempt all questions in brief, laxz020 @. | Define chromophore with example. b. | Give the significance of functional group region in IR spectroscopy. “c| Explain quenching? d © f Give the radiation sources of IR spectroscopy. ‘What is the role of nebulizer in flame Photometry, Write the advantages of panition column chromatography. &. | Define RF values. hi | Write the applications of HPLC. 7. | What are the main disadvantages of gas chromatography, j. | Give the examples of ion exchange resins. 7 SECTION B > \ 2x 10=20 Attempt any peaparts of the following: Write a note on Instrumentation of UV -VIS spectroscopy. %) Give the brief idea on mechanism of ion exchange process’and factors affecting ion exchange. - SECTIONG)” 3 Attempt any five parts of the following: - Wx5=35 ‘a. | Describe the various methods of sample preperation for IR analysis. i. ] Drawa Schematic diagram of AAS and discuss the radiation sources. T | Write the instrumentation of ion exchange chromatography, g. | Describe the factors affecting gel electrophoresis technique.Printed Page: 1 of 1 WON A Subject Code: BP702T natn ott BPHARM (SEM Vil) THEORY EXAMINATION 2021-22 INDUSTRIAL PHARMACY II Time: 3 Hours Total Marks: 75 Note: 1, Attempt all Sections. If require any missing data; then choose suitably. SECTION A Attempt all questions in brief. 10x 2=20 Mention two major applications of platform technology. Mention the basic role of SUPAC guidelines. ‘Name at Teast 4 agencies responsible for successful technology transfer in India State the role of one major TT agency of India. State to important functions of the Regulatory Affairs Department. What do you mean by "Non-Clinical Drug Development’? What do you mean by ‘Six Sigma concept’? Mention the specifications of ISO 14000 series of quality systems standards. State the responsibilities of CDSCO, oO , a] Mention the significance of COPP. af : AO 1 Js e]s =| 5 ow SECTION 2, __Attempt any two parts of the following: a] Describe the various approaches for desighing controlled release formulation: suitable examples. ao B. | Describe the working principles and applications of implants and osmotie pum c. | Explain the formulation approaches of Transdermal Drug Delivery Systems to 210520. ny ‘overcome the barrier effects of'skin ni WS MS, SECTION C ‘ 3. ___Attempt any five parts of the following: 7x5=35 a. | Classify polymers on functional basis. x b. | Write a brief note on transmucosal permeability and formfilation considerations for buccal drug delivery systems. Describe the formulation approaches for gastro-retentivé drug delivery systems Explain the jous drug targeting approaches . | State and explain the significance and limitations of naso-pulmonary drug delivery systems, ow f | Explain in brief the various methods t-Gvercome ocular barriers for effective drag delivery. sO La._| Write a brief note on the development-and applications of intra uterine devices (IUDs). reWd / Sehject Cade: BPTOIT Roll No: B. PHARM (SEM-VID THEORY EXAMINATION 2020-21 INSTRUMENTAL METHODS OF ANALYSIS. Time: } Hours Toral Marks: 75 Note: 1. Attempt all Sections If require any missing data; then chouve suitably SECTION A Attempt aff questions in brief. 10x2=20 “Define chromophores and auxochromes “What is absorptivity? What are different types o White about hollow cathode famp || What is the difference between normal phase and Feverse phase chromatngraphy? | What is electrophoretic mobi [e| What is HETP? Give its significance. i | What is Fedy diffusion? i] Write two examples each of cation and anion exchangers, T_| Enlist the advantages and disadvantages of agaroué and polyacrylamide geh aa (sition 8 R Attempt any fwo parts of 22s t0=0 [a ] Enlist the different components-of uv-visible specttophowmeier und explam the working of double beam spectrophotometer along with well labeled diagram. ) ». | Explain principle, instrumentation, and application of flame . | Discuss about principle and instrumentation of HPLC. SECTION C 3 Attempt any five parts of the following: 7Tx$=35 IB] ‘What is Lambert-Beer's law? Explain its deviations along with quantitative applications. ‘Compare the working of dispersive IR and FTIR instruments. Explain working of FTIR in detail. > iat Explain principle, instrumentation, and application of fluorimety. Explain principle, methodology with applications of ion exchange chromatography. [2 | What is electrophoresis? Explain different types of electrophoresis techniques with their principle and applications. ‘Write about principle, methods. and applications of TLC. B- | Write note on theory and working of gel electrophoresis, https://Awww.aktuonline.comWO a Printed Page: tof | ‘ubject Code: BPTO3T PAPER 10-31 ‘aaa manne BPHARM (SEM VII) THEORY EX, yqNATION 2020-21 PHARMACY pracTICE Time: 3 Hours Total Marks: 75 }+ Attempt all Sections. If require any missing data: then choose suitably. SECTION A Attempt alf questions in brief. 10x2=29 _| Define Medication Adherence. Enlist Causes of Medication Non-adherence. Write about the location and size of Pharmacy as pet Tadian Public Health Standards. How adverse drug event is different from advene drug reaction? What do you mean by Medication History Interview? . | Comment on Role of Pharmacist in the Interdepartmental Communication. Write objectives of “Code of Ethics” for pharmacist. 3. = Enlist objectives of hospital pl and deseribe the functions of hospital he zt Pharmacy. | b. criteria for adding drugs in the formulary. ” Write in brief about concept of clinical pharmacy and elaborate the scope of clinical ha ise | Define hospi _ Write a note on material management m community pharmacy. Define Role of Pharmacist in Drug therapy monitoring. How Pharmacists play a crucial role in budget preparation? Define “false-positive test result” with suitable example. Enlist various biochemical test performed during urine analysis. SECTIONB _ Attempt any fwo parts of the following: 2x10=20 nd classify hospitals on the basis of different aspects. _ formulary. Describe the types of hospital formnularies and highlight the Define hospi macy. SECTION C Gs Attempt any five parts of the following: $ 5x7=35 Classify Adverse Drug Reaction and define different types of ADRs with suitable examples. | Describe the organizational structure, functions” of Pharmacy and therapeutic c, | Write about the history and objective of drug information service. Describe sources oF _ drug information. committee. Define and classify ‘Over-the-Counter (OTC) Medicines. Discuss about the Indian nario for OTC medicines. Describe the techniques of inventory management https://www.aktuonline.comtH feted BETOET PAPER iD. aa rT Set Codes BRE RollNo: | | | Ses B PHARM (SEM-VI) THEORY EXAMINATION 2020-21 . NOVEL DRUG DELIVERY SYTEM Time: 3 Hours Total Marks: 75 Note: 1. Attempt all Sections. If require any missing data; then choose suitably. SECTION A 1. Attempt aif questions in brief. Latelitite \& Define microparicles SS SSSSSSSSS~Sd “f, | Polymer Matrix Diffusion-Controlied DDS ‘Define Hydrodynamic pressure actwate DDS | ae : —_—— ee FS considered while development of nasal drus del}Mery system. ; Biomedical applivation of Nasal DDS Classify polymers SECTION B L 2. Alfempt any swe parts of tic following: 2x10=20 a, Discuss implantable drug délhry systene with special ee pump. | | Enumerate formulation HpyWoaches ofTDDS, €. Development of IUDs. What are its advaniages & disadvanpfe@? sectionc , 3. __ Attempt any five parts of the following: SL, 7xS=35 (Define targeted drug delivery systema wade e is appoaies a be ‘What are intra ocular bantiers? Write acdip'on ocusert | Discuss metered dose inhalers. & Alrite a note on liposomes. ni ‘Explain the principles of bivauhesion, Give advantages andl _ omg deliv ey system. © Drowa neat ibe diagram of skin, Discuss the factors alice https:/Avwww.aktuonline.com