Labetalol is used for acute ischemic stroke treatment to lower blood pressure below 185/110 mm Hg prior to alteplase administration, and below 180/105 mm Hg for the first 24 hours after treatment. It is given as a 10-20 mg IV dose over 1-2 minutes, and can be repeated once, followed by a continuous infusion of 2-8 mg/min if needed to control blood pressure. The patient should remain supine during and for up to 3 hours following injection. Nitroprusside is contraindicated if raised intracranial pressure is present and should be avoided in patients with hypertensive encephalopathy or following a stroke, as well as those with renal or hepatic
Labetalol is used for acute ischemic stroke treatment to lower blood pressure below 185/110 mm Hg prior to alteplase administration, and below 180/105 mm Hg for the first 24 hours after treatment. It is given as a 10-20 mg IV dose over 1-2 minutes, and can be repeated once, followed by a continuous infusion of 2-8 mg/min if needed to control blood pressure. The patient should remain supine during and for up to 3 hours following injection. Nitroprusside is contraindicated if raised intracranial pressure is present and should be avoided in patients with hypertensive encephalopathy or following a stroke, as well as those with renal or hepatic
Labetalol is used for acute ischemic stroke treatment to lower blood pressure below 185/110 mm Hg prior to alteplase administration, and below 180/105 mm Hg for the first 24 hours after treatment. It is given as a 10-20 mg IV dose over 1-2 minutes, and can be repeated once, followed by a continuous infusion of 2-8 mg/min if needed to control blood pressure. The patient should remain supine during and for up to 3 hours following injection. Nitroprusside is contraindicated if raised intracranial pressure is present and should be avoided in patients with hypertensive encephalopathy or following a stroke, as well as those with renal or hepatic
💠 acute ischemic stroke regimen : Pretreatment, 10 to 20 mg IV over 1 to 2 minutes, may repeat x 1
dose to achieve blood pressure (BP) less than 185/110 mm Hg prior to alteplase; if BP exceeds 180/105 mm Hg in first 24 hrs after alteplase treatment, administer 10 mg IV followed by a continuous
💠 infusion of 2 to 8 mg/min (guideline dosage). patient should remain supine during and for up to 3 hours following injection . Hydralazine GTN Nitroprusside ●
● if raised intracranial pressure is present or suspected, nitroprusside is
contraindicated ● Nitroprusside is disadvantageous in patients with hypertensive encephalopathy or following a stroke. should also be avoided in patients with renal or hepatic insufficiency.
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