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Introduction
A medical device is defined as implantable if it is either partly or totally
introduced, surgically or medically, into the human body and is intended to remain there
after the procedure. Millions of people worldwide depend upon implantable medical
devices to support and improve the quality of their lives. The great impact of implantable
devices was first shown by the introduction of pacemakers in the early 1960s, which
enabled monitoring and treatment within the human body. Implantable Medical Devices are
used presently to perform an expanding variety of diagnostic and therapeutic procedures
enabling the control of human functions as well as data on the patient’s status. Implantable
medical devices are already used in variety of applications according to their functions.
Basically, two categories, first category includes all those devices used to diagnose various
diseases. These Implantable medical devices in addition to their communication system with
the external environment includes some sensors that interact with the human body to
measure the necessary physiological information. This category includes microsystems
implanted within the human body to monitor important biological signals such as
temperature monitor, blood glucose sensor etc. The second category includes implantable
devices used as stimulators. Stimulators receive information from an external unit (usually
managed by doctors) and stimulate (irritating) specific nerves. Such devices are pacemaker,
retinal implants etc. Essential element of implantable devices are antennas embedded in
such systems, which enable the exchange of data between implantable devices and external
environment.
Fig. 1.1 Wireless Implantable Medical Devices
1.2.1 Biocompatible
Implantable antennas must be biocompatible in order to preserve patient safety and
prevent rejection of the implant. Biocompatibility is defined as the property of some
materials do not cause toxic reactions or effects or injuries in the human body. This means
that the host, the human body and its immune system, is not directed "against" this
material. Furthermore, human tissues are conductive and will short-circuit the implantable
antenna if they are allowed to be in direct contact with its metallization. Also, the
performance of the antenna can be degraded. There are some approaches for preserving
the biocompatibility of implantable antennas and separating their metallic parts from the
surrounding biological tissues such as covering the antenna structure with a biocompatible
superstrate dielectric layer or insulating the antenna with a thin layer of low-loss
biocompatible coating and use biocompatible material to build the structure. Maximally, the
substrate which is used to design implantable antenna, is also used as biocompatible
superstrate dielectric layer. Also, silicon can be used as biocompatible coating which is a low
index biocompatible material. Several biocompatible materials which can be used as built
the structures of antenna such as Graphene, Titanium alloy, alumina etc. Also, if the
thickness of the biocompatible coating is increases then the resonant frequency is shifted
and axial ratio also affected.
1.2.3 Miniaturization
Miniaturization becomes one of the greatest challenges in implantable-antenna
design, with the aim of new technological developments in IMD electronics, leading to ultra-
small antennas. The dimensions of the traditional half-wavelength (λ/2) or quarter-
wavelength (λ/4) antennas at the frequency bands allocated for medical implants and
especially at the low-frequency MICS band, make them impractical for implantable
applications. Because, at lower frequency, the dimension of the antenna is very large.
Several techniques are there for miniaturization such as: -
Use substrate with higher dielectric permittivity but bandwidth and efficiency is
reduced. Because the bandwidth is inversely proportional to the square root of
dielectric permittivity. As bandwidth is reduced that’s why efficiency is also reduced.
Using shorting post at appropriate location. Due to shorting post, the effective length
of the antenna is increased that’s why resonant frequency of the antenna is reduced.
But the effective width is decreased, so the effective aperture area is reduced and
also radiation efficiency is reduced. So that bandwidth is reduced. Due to increase
the length of the antenna, the surface current path length is also increases. So that
cross-polarisation problem can be arising.
Cutting slot at appropriate location. Also, the resonance frequency decreases
because effective length i.e., current path is increase. But bandwidth and efficiency is
also decrease due to small width i.e. aperture area decreases. If slot dimension
increase, then feed point close towards the centre because of impedance variations
or also we take shorting post to get impedance matching.
Any combination of the above techniques is used for miniaturization.
Also, vertically stacking two radiating patches reduces antenna size by increasing (nearly
doubling) the length of the current-flow path.
1.2.4 Wide Bandwidth
The antenna is implanted inside the human body, it is prone to frequency
detuning such as resonance frequency shift due to distribution of tissue at the implanted
location of the antenna is inhomogeneous and also due to the implant depth. So, this
problem can be reduced by antennas wideband property. Bandwidth of the Microstrip
antenna can be enhanced by several techniques such as using parasitic patch, using
substrate with low permittivity and by stacking microstrip antennas. But for these
techniques the volume of the antenna can be increased which can’t be ideal for any
implantable antenna because the implantable antennas should be compact in size or
electrically very small. Also, recently slot loading technique, slotted ground plane etc. are
used to enhance bandwidth of the implantable antenna.
Table 1.3- Parametric analysis of dielectric constant of muscle tissue for different age at
400MHz MICS Band
Table 1.4- Parametric analysis of dielectric constant of muscle tissue for different age at
2.45GHz ISM Band
The main influence of the high conductivity and permittivity is the significant increase of the
attenuation loss. This attenuation can be calculated inside the body human tissues using the
following equation
Where α (Np/m) is the attenuation constant, Lα (dB) is the attenuation loss, Ꙇ (m) is the
distance from antenna in the tissue to the skin surface. The attenuation constant can be
calculated using equation
(√ )
1
1 σ2
α =ω √ με 1+ 2 2 −1 2
(1.3)
2 ω ε
Where ω (rad/m) is the angular frequency, μ is the tissue permeability (H/m), ε (F/m) is
the permittivity and σ is the tissue conductivity (S/m). The tissue permittivity can be
calculated as:
ε =ε 0 ε r
Where ε 0 is the free space permittivity and ε ris the relative permittivity. The human body
tissues are non-magnetic and, therefore, the human body tissues permeability μ (H/m) is
equal to free space permeability μ0.
There are additional losses in the human body due to reflections between the tissues at
the boundary during the signal travel. These losses can be calculated using Equations
Lr =−20 log 10 ( Γ ) (1.4)
η2−η1
Γ=
η2 + η1
η=
√ jωμ
σ + jωε
Where η (Ω) is the intrinsic impedance and Γ is the reflection coefficient at the boundary
between tissues.
Fig. 2.2 Geometry of the stub-loaded dual-band implantable antenna (unit: mm) [24]
(a) Top View (b) Side view
R. Liu et. al. proposed a wide band compact circular polarized implantable antenna [27]. A
circular radiator is cut four L-shaped slots and loading a short pin between the radiator and
ground plane to implement circular polarization. Two crossed rectangle slots are etched on
the ground plane that the impedance and Axial Ratio bandwidth expanded. Also, SAR value
satisfies the IEEE standard safety guidelines. `
Chapter 3
Design a Implantable Microstrip Patch Antenna for
Biomedical application at 2.4 GHz ISM Band
3.1 Introduction
In general, microstrip antennas are half wavelength structures and are operated at the
fundamental resonant mode 𝑇𝑀01 𝑜𝑟 𝑇𝑀10, with a resonant frequency given by:
c
𝑓¿ where c is the speed of light, 𝐿 is the patch length of the rectangular microstrip
2 L √ϵr
antenna, and εr is the relative permittivity of the grounded microwave substrate. The
1
radiating patch has a resonant length Lα and the use of microstrip substrate with a large
√ ϵr
permittivity can result in a small physical antenna length at a fixed operating frequency.
With a size reduction at fixed operating frequency the impedance bandwidth of microstrip
antenna is usually decreased. One can simply increase the substrate thickness to
compensate for the decreased electrical thickness due to the lowered operating frequency.
But as the height of the antenna increases losses due to surface wave effect and extraneous
radiation result in poor performance characteristics. Usually, substrates with εr ≤ 10 are
preferred. With a substrate of low dielectric constant, the fringing fields that account for
radiation will be enhanced. But in order to obtain smaller patch size substrates with high εr
are required. Thicker substrate besides being mechanically strong will increase the radiated
power, reduce conductor loss and improve impedance bandwidth. But it increases the
antenna weight, dielectric loss and surface wave loss.
A large number of implanted antennas have been presented the literature. However,
they can be classified into two categories; the first one is subcutaneous implanted antennas
or antennas to be placed in a fixed area of the body, and the second category is implantable
antennas that move through the body such as capsule endoscopy. However, several
requirements are there for design an implantable antenna such as compact in size,
wideband in bandwidth, biocompatibility and maintain standard SAR value which is in 1-g of
tissue must not exceed 1.6 W/Kg. Patch designs are most commonly selected for
implantable antennas because they are highly flexible in design, shape, and conformability.
Moreover, circular structures are very often preferred in an attempt to avoid sharp edges,
which may hurt the surrounding biological tissues. In this report, a compact implantable
antenna for biomedical application at 2.4 GHz is proposed.
Fig. 3.1 shows the geometrical structure of the proposed antenna, which has a centre
square slot and six slits. The proposed antenna is fed along the x-axis, and the distance
between the feed point and the original point is 4.35 mm. Both the superstrate and the
substrate are made of Teflon which have ε r=2.1 and loss tangent tan δ=0.0002 and
thickness of 1.25mm.
Four types of implantable antenna case are studied. Fig.3.2 of case 1, the initial implantable
antenna is a traditional linearly polarized patch antenna with a centre slot. The resonant
frequency of Case 1 is 4.1 GHz, which is much higher than the 2.4-GHz ISM band. To achieve
a lower resonant frequency, three pair of slots introduced in case 2 of Fig.3.3. The resonant
frequency of case 2 is 2.6 GHz which is slightly higher than 2.4 GHz. Further, to reduce the
resonant frequency, another pair of slots introduced in the final design of Fig. 3.1. The
resonant frequency of this final case is 2.41 GHz which is in the ISM band.
3.3 RESULT
The designed antenna is studied in a cubic one-layered-skin model. In a practical situation,
the radiation environment, human body, is quite complex. Many factors impact the
radiation characteristics of the implantable antenna. Both the conductivity and permittivity
of the tissue essentially impact the reflection coefficient, and gain of the antenna. Fig.3.7
shows the simulated reflection coefficient S11(dB). The simulated S11 bandwidth below -10
dB ranges from 2.32 GHz to 2.61 GHz (12.04 %). Fig. 3.8 and 3.9 shows the realized gain
pattern obtained from one-layered skin model. The max realized gain achieved about -
11.05dBi in the boresight direction.
3.3.2 Directivity
4.1 Conclusion
In this report, a compact wideband implantable antenna operating in ISM band at 2.4
GHz proposed. The antenna is excited by a 50-ohm coaxial probe feed. Slots are created in
the patch to lengthen the current path and also reduce the resonant frequency. All
simulation results are discussed and analysed. The major parameters like return loss curves
and 2-D polar pattern of gain are studied. The overall antenna size is 20 × 20 × 2.5 mm 3.
Also, the overall impedance bandwidth of 12.04 % is obtained. The antenna is simulated in
skin layer. After analysing the results, we can select the required antenna as per our
requirements.
4.3 Reference
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