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Booth & Stoia Anatomy, Physiology & Disease for the Health Professions 1E - IM Chapter 2
Overview
Chemistry is the study of matter and how it undergoes change. Regardless of the field you have
chosen to go into, an understanding of chemistry can make life more satisfying. Everything we
come into contact with is made up of chemicals. Even our bodies are made up of chemicals.
Learning Outcomes
After completing this chapter, the student should be able to:
2.1 Identify matter and its characteristics.
2.2 Classify important inorganic substances.
2.3 Classify important organic substances.
2.4 Explain how chemical changes impact lifespan.
Lecture Outline
Case Study (LO 2.4)
o Dehydration: Adam Rooke, a 74-year-old man, was working on his car on a hot
summer day. He became dizzy and had to sit down to rest. His pulse was weak but
he was not perspiring.
Introduction (LO 2.1)
o Chemistry is the study of matter and how it undergoes change. Biochemistry is a
branch of chemistry that deals with the chemistry of life or biological chemistry.
o When two or more atoms are chemically combined, a molecule is formed. Molecules
are the basic units of compounds. A compound is formed when two or more atoms of
more than one element are combined.
o Atoms are held together by chemical bonds. Energy is stored in chemical bonds.
When the bonds are broken, energy is released that can be used by the body. When
bonds are formed, energy is required. Two of the more important chemical bonds we
see in cells are covalent bonds and hydrogen bonds. Covalent bonds are when two
atoms share the same electrons. A hydrogen bond is an attractive intermolecular
force between two partial electric charges of opposite polarity.
o Metabolism is the sum of all the chemical reactions that take place in our body. The
two processes of metabolism are anabolism and catabolism. In anabolism, small
molecules combine to form larger ones. In catabolism, larger molecules are broken
down into smaller ones.
o PPT slide 2-3 to 2-7
Matter and Atomic Structure (LO 2.1)
o Matter is anything that takes up space and can be a gas, liquid, or solid. Matter is
made up of substances called elements that are made up of the same atom.
o An atom consists of a nucleus which is at the center of the atom. The nucleus may
contain a number of neutrally charged particles called neutrons and positively
charged particles called protons. Neutrons and protons have approximately the same
mass.
o Surrounding the nucleus, we find a number of negatively charged particles called
electrons. Their mass is so small compared to protons and neutrons we say they have
no mass. Electrons farthest from the nucleus are called valence electrons. Valence
electrons are gained or lost to make a molecule more stable or may be shared as in
covalent bonds.
o The atomic number of an element is the number of protons in the element. The
atomic weight is the sum of the number of protons plus neutrons.
o Matter can be divided into two large categories: organic and inorganic matter.
o PPT slides 2-8 to 2-16
Inorganic Substances (LO 2.2)
o Water is the most abundant inorganic compound in the body and is an essential
component of our cells, our blood and many other body fluids. Because it takes a lot
of energy to change the temperature of water, it helps to regulate our body
temperature.
o Oxygen is another essential inorganic molecule. We inhale oxygen, and then it is
transported through our blood attached to hemoglobin within red blood cells to all the
cells and tissues of our body. It helps to convert glucose to needed energy.
2
Booth & Stoia Anatomy, Physiology & Disease for the Health Professions 1E - IM Chapter 2
o Carbon dioxide is exchanged in the cells for oxygen. The carbon dioxide is then
exhaled. Although carbon dioxide is considered a waste product for us and other
animals, it is essential for most plants and is used to make oxygen.
o Inorganic salts are the fourth major category of inorganic substances that are
important to life. They consist of ions such as sodium (Na+), chloride (Cl-),
phosphate (PO4-2), potassium (K+), calcium (Ca+2), magnesium (Mg+2),
carbonate(CO3-2), sulfate (SO4-2), and bicarbonate (HCO3-). They are involved in
many important metabolic functions.
o PPT slides 2-17 to 2-19
Organic Substances (LO 2.3)
o Carbohydrates are our body’s main source of energy. Sugars are one category of
carbohydrate and they are soluble in water. Sugars can be classified as simple or
complex depending on their size. The most common carbohydrate is glucose which
contains 6 carbon atoms, 12 hydrogen atoms, and 6 oxygen atoms in every molecule.
Besides being an energy source, carbohydrates are used to build some structural units.
o Lipids are fats and are insoluble in water. The three types of lipids found in the body
are triglycerides, phospholipids, and steroids. Triglycerides are used to store energy
for cells. A major function of phospholipids is to make cell membranes. Steroids are
very large lipid molecules used to make cell membranes and some hormones.
o Proteins have many functions in the body. Many proteins act as structural materials
for the building of solid body parts. Other proteins act as hormones, enzymes,
receptors, and antibodies.
o Nucleic Acids or DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) are two
examples of nucleic acids. Nucleic acids are large complex molecules made up of
carbon, hydrogen, oxygen, nitrogen, and phosphorus. DNA contains genes, or the
genetic information of cells, and RNA is used to synthesize proteins.
o PPT slides 2-20 to 2-24
Life Span (LO 2.4)
o Chemical changes occur as we get older and also when we become ill.
o PPT slide 2-25
3
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will allow. Hold all these folds flat and close, and with a small
pinching cord give one turn round the middle of the cracker and
pinch it close; bind it with pack thread as tight as you can, then in the
place where it was pinched prime one end and cap it with touch-
paper.
When these crackers are fired they will give a loud report at every
turn of the paper: if you want a great number of these, you have only
to cut the paper longer, or join it on to a greater length; but if they are
made very long you must have a piece of wood with a groove in it
deep enough to let in half the cracker, which will hold it straight while
you are pinching it.
Rockets.
There are several recipes for making rockets, the best of which is 3
ounces of charcoal, 6 of sulphur, 8 of niter, 32 of meal powder.
Another very good one is, 3 ounces of iron filings, 4 of powdered
charcoal, 8 of sulphur, 16 of niter, and 64 of meal powder. If a
smaller quantity is wanted divide each proportion by 2, if a still
smaller divide by 4.
Rains.
Sometimes gold or silver rains are added to rockets, which give them
a very beautiful appearance. A gold rain is made of 2 parts sawdust,
4 sulphur, 4 meal powder, 6 glass dust, 16 niter, in all 32 parts. A
silver rain may be made of 2 parts salt prunella, 8 sulphuret of
antimony, 8 sulphur, 8 meal powder, and 14 niter, in all 32 parts.
Catherine Wheels.
These are very pretty fireworks, and are made to turn on a pivot.
There are many recipes for the composition of which they are
formed; 1 part camphor, 1 sulphur, 1 niter, 2 meal powder. Another
is, 3 parts iron filings, 4 sulphur, 12 niter, 16 meal powder. This
composition is to be rammed into small cases, and bound round a
small wheel having a hole for a pivot in the center.
Crimson Fire.
The principal ingredient in this is nitrate of strontium, of which 40
parts are taken, with 13 of sulphur, 15 of chlorate of potass, 4 of
sulphuret of antimony, and 2 of lamp-black. These, as all the
ingredients for the other fires, should be rubbed in a ladle, and they
may be used in a ladle or iron dish set on the ground.
Blue Fire.
The ingredients of blue fire are 20 parts; 12 of niter, 4 of sulphur, 2 of
sulphuret of antimony, and 2 of lamp-black.
Green Fire.
The ingredients for green fire are in 54 parts; 42 of nitrate of barytes,
8 of sulphur, 3 of chlorate of potass, and 1 of lamp-black.
Purple Fire.
The best recipe for purple fire is of 60 parts; 25 of niter, 25 of nitrate
of strontium, 7 of sulphur, 2 of realgor, and 1 of lamp-black.
White Fire.
The best and purest white fire is made of 24 parts of niter, 7 of
sulphur, 2 of red arsenic, and one of lamp-black.
Spur Fire.
9 parts of niter, 4 of sulphur, and 3 of lamp-black, well rubbed
together.
Blue Lights.
These are made of 4 parts of sulphur, 2 of niter, and 1 of powder,
and are rammed into squib-cases the contrary way.
Port or Wildfires.
Saltpeter 4 parts, meal powder 6 parts, and sulphur 3 parts. The
composition to be moistened with linseed-oil.
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Transcriber’s Notes:
The one footnote has been moved to the end of its section.
Punctuation has been made consistent.
Mathematical notation has been standardized to current conventions. For
example, the notation 1-2 for fractions has been changed to 1/2.
Variations in spelling and hyphenation were retained as they appear in the
original publication, except that obvious typographical errors have been
corrected.
p. 14: There is no illustration in the original book (This illustration represents)
The following change was made:
p. 7: 2 changed to 3 (No. 3, it)
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