YMATCTBO BO NAKYBAHSETO/MH®OPMALIAJA 3A MAUMEHTOT Clexane 6000 arr-Xa IUI0.6 ml, pacTBop 3a mujextuparse Bo ‘nperxoawo nanonwer wnpmu, CClexane 8000 antw-Xa IUI0.8 ml, pactuop 3a unjexrupaise Bo ‘nperxoawo nanonwer wnpmu, CClexane 10000 arrrv-Xa IU mi, pacraop 2a unjoxTuparse Ho npeTxoaNo wanonwer wpm, ‘enoxaparin sodiumienoxcanape Harpy pea ynorpe6a wa niexor, nmwavenno npowrajre ro ynarcrsoro! > Yyeaime 20 ynamcmeome. Mowe6u fe mpe6a 0a 20 npowumame nosmopro. > Ako umame dononumenny npawarsa, oSpameme ce Kaj Bauuom nee tunu gpapmauesin. > Ocoj sex Bu © npenuuaH Baw suxno u ne mpebsa Oa uM 20 daeame Ha Spyeu nus Gudejku woxe 0a um awmemu dypu u AKO HuEHUME ‘cunmomu ce ucrmu Kaxo Bawume. 1 Ao ce jaeu cepucsno nscaxano Gejemeo unu aKo saGenexume vecaKaHO {ejemeo noe He e onuuiaKo 80 dea ynamemen, eedHaU! KAKEME MY HO ‘Bawuom nexep unu cbapwausern. YnarcwBoro compat: 1. Lume npememaeyea CLEXANE*y 3a wmo ce ynompesyea 2.lumo wopa da suaeme nped da 20 ynompesume nerom CLEXANE® 3. Kano 0a 20 ynompe6yeame nexom CLEXANE® 4 Movowu necaxanu Oejomea ‘.Karo da 2o wyeame nexom CLEXANE* @dlononiumennu wicbopmauu 1. WTO APETCTABYBA CLEXANE* 6000 aumrXa 1/108 mi, 8000 ‘inna 08 i 10000 sce Wt ml, paevoop su merteperee W3A ilo Ge norpesven Ong] senator qpomens © aero ¥ rpurta va ntcaNT KH co raponaasr wxcouonenyneper senepu To) fe cpesyed apap va. pow apyeosann’ so bone ww eprepune ipowscta, aro A ‘acre nowt yom Fcrowonecnapore senepinu Move 288 npennuyeaar Geo rene pnt co con SpmPowere 28 Ko Spyrjeaca vowparue caoo : + ka epara,ore pane pyrene ce ete Gopylfeat ‘Tepanevcren wiaunayun (Oso) wanaupncar nporason ce ynorpesyaa:‘+ aKo nware KpeHM srpyTayaaiea Bo BeHiTe (‘PNeOUTHC), CAMOCTOHHO HH ‘saeano co Gnowipan npoTOK Ha ¥Ps BO apTepmaTe BO GeruTe ApoCoRM (Genoapotna enconaja) ‘+ aKo mmrare ogpanen Tan Ha KoponEpHa aprepuoxa Gonect Gonect Ha poHuTe cagosn Ha cpueTo) ‘+ ano cre mane cpues yaap (wmoxapavjanen vecbapxr) 4 cre wa repanwia co TponGonmm (nex Ko) nowara 80 paarpanyeaise Ha xperure arpyreypatea). 2. WTO TPEBA A SHAETE NPE A TO YNOTPEGMTE NEKOT CLEXANE*6000 axru-Xa IU/0.6 ml, 8000 axrw-Xa IU/0.8 mi, 10000 faune-Xa UM mil, pacraop 3a unjextupare CLEXANE* HE CME na co ynorpe6yna uo cnenverre crys [__ Mlexor CLEXANE® Texor CLEXANE" ne €8 |_sorpannainuypan sayrorpe6a | _npenopasyea sa ynonpeta oo re ane xo yorpetjeare: arp (0 a (npesyecrarranmy) #2080) ou Go xopworar 38 Sonva # 7pecis), Neawuyonr npovaoa, Ha Necrepovaii arramndnausropan enapin vou a gepaearn Ha ‘nesoon (HCAIAR) une aoecrpak enapin, skaysyeayin aw apyrive | + So npmaTe wevonky aeNa no MesONeN ‘wnexoMonenynapu xenapuen RRP 63 woBApeNE, + Bko npersoane ere mane + Beowmare OrapRUTHE (OKI ‘cepvoavo nauanyaaiee Wa pojor |" a epyero}eo noronenwor Spo) na a TpoMSowia (pia anos) nya Npeausaneavo co xenapvw ‘+ ako mare Garo ao yuspeo (mpoweouumume vepaam urorysaise a GySpeaire suavaia yrose #0 Sapyrmuyearoeme va xpama} ano mate aabonyeatwe roe ro apyuyea srpyrsyeaieevo va pera + sko wae earao Guno ‘urerysaice (skarpeuo una ragnopeue) woe wax aa Kovapyt + Skovare eoeapeiee wo uos0Kcr + ako mare Teun oureryeane na 6yopearre; ‘+ ako peta 2a np ‘ennaypanva wr conan | ‘Buocroana (ooo Tanoam a Z [necreayja ce ronpannanuypann 5a epee Wa peTuaHor co Clexane) ano mur TouKo epeapene, Moce6nn npezynpeaysaiea w MepKH Ha npeTnasnuBocT NpH sige y va nexot GLEXANE® Flocebin npeaynpeaysarea:+ 22.28 oe miBente rpeapeibe, mory © BaNHo Aa He ce npevexopn RosaTa spemerpaeivero na nexyearseTa kOe © npenwtilaro Oa Bausnor AOKTOD. + Sa opome ia nenysarseTo uHory © aaxHo peryfapHO fla ce nposepjoS DSpojer Ha tponBouir (Hajvecro @ aosonvo ABanaTH Keen) + 32 spewe Ha tpermanor co xenapin, eo peTk CmyaM MOE Aa Ce sabenonn sHauapo HamanyBaree Ha Opojot Ka spomBoiyin. Bo oBre ‘onysan @ novpeOHo fa ce npeKme neKyBabeTO Co xenapH H Aa Ce ‘cnposene aaonne wonvroprer 3a za ce cnpewi nojasara na cepnostt otnnKauin, ccoBeH0 TpowGosa WTO @ napeAoxcarMo Ha NpeTHOAMVOT aon. + O80} weavviicit nponseog He ce npenopayysa 2a ynowpeta taj neu, VINJEKUMMTE HE CMEE fA CE fIABAAT VHTPAMYCKYMHO! Vecrpynnire 3a wejecrypase Ha nekor rpeGs SaBOMMMTEMO Ad oo noweryeaar, Npernasnusoct npn ynowpesa: Karo npa ynorpeBa va gpyrure summcoarynesrin nator, woKe fa 08 jas paapeise. Bo cnysal na nojaea wa ipsapebe, Tpeda fa ce nneNTucbimyee "pwsieiara a ypsaperueTo n na c2 npeaeMer coonBeTN Tepanvel WepKt o Herom crysam, ocoBeHo npr yno7peOa Kako KYPATHBeM TPETMN, MOKE. Reh ‘a sronenwen prvi On KDeaperBe H TOA Kae + -mocrapie aiatynenra: + faxes co TenecHa tema nowana oA 40 kg; ‘+ naires co ouerena Gytunja ha Byopeaur + 8X0 nexyearsero npagorexyea nogonro oA eooGuaeNorO Tpaeree OA 10 aor; + 2x0 rexor ce ynorpedysa wo KonGwiatina co oApeRsHn Apyrw exoen {enaete nen Yrorpeta na gpyru nexosw), ‘+ aX0 nexoT ce ynoTpeSysa co Apyra nexOSU Kow ro sronemyeaar prawKoT (4 xpaapaise (aimete zen Yoorpebia Ha Apyru meno) ‘pv ene cocroj6u norpetHo © noceBwo cneneive a naLaeHTTe: HaAZOp \emmyeaiea op crpaa Ha neKap x, x0 © RETpEGHO, seNearse Ha roMMEDoUE a ips 2a snare. ‘AKO mare wit nperxoqHo CTE aware npOBneke co YPAMOT POO ve SyOpeanre, yrizepausan (wnpesH) msi ApYTA Nan Kon MOMe 22 KpSepar, ‘expopumpajre ro Baunor neKap. ‘Ako HeKoe on nperxonvo HaBexeNTs NpeAyTpeRysaiba ce ogecyBa Ha Bac witbopwmmaire ro Baumor noxap. Ynorpe6a wa apyrm nexoon SApaqH preMKOT GR xpBapeIKe CevoraLl HopuNpee ro BaUNOT neKap” = L fs ‘3x0 SeMaTe Hekoj aX chenwre nexcaH: + acnvus, + Hecrepongi aimanbnawaropin neroed (HCAVA), + woutGuropn Ha arperauvjara Ha TpouGowyrin ‘enmiebriarna, nnonpocr, tEnonAaMk, THporpvGan), ‘+ nokerpex (nex 1oj ce nopucmu eo uamenouena Hee8),+ nepopenia axrioarynaim neKoeH (neKoeM KOR ro wataryeaar axpyruysaibero na wpsTa npory wepaOnuvja Ha BvraMnHoT Be wonuwo da 20 uikbopuupame Bauuom nexap ako aeuame und aKo 00 eo¢ania cme seuane Koj Ouno dpye nex, Oypu u oHue KOU He O8 Ha ‘mexaperu peyenm. 80 coanaciocm co mos, Bawiom ‘exep Ke 20 ‘npunaeodu Bawuom mpemuan, Bpemenocr w noeiwe Spewevoom | Jlekor He ce noenopayysa sa ynovpeGa sa spewe Ha Gpemenocra, Bausor ‘Aoxrop rpeS ja npousHa arnt Bi @ HeorKoRva Tepsniga co Nevo ‘Ano saOpeweHure 3a BpeKe Ha NekyBarETO, KOHCYMUpaTe ro BaUunOT jnerap w Tojfraa ke opnysn 3a norpebara OA Har=MOILMO NDOROMVBeee Me pertiaror. Cosemysaime ce co Bawuom nexap nped da 2eueme KaKoe Bund ne Dose CCLEXANE*He 0 konrpamianpan Ka) xeh xoM Aja, costo npasuno: axo cme Gpewenu unu doume, ussecmeme 20 Batwoom -neKep nu cbapwawosm nped da seweme KaKoe Guno Nek. Bnutjanue aps cnocosnocra 3 TlecoT Hema erujesne eps ciooSocTa 2a soseise Ha asToMoGvin Hm arysaive co aun, JoseWwe Ha aBTOMOGHA HM paxyaaise co 3. KAKO CE YMOTPEBYBA NEKOT CLEXANE*6000 aimi-Ka 1U/0.6 ‘ml, 8000 arr-Ka 1UI0.8 mi, 10000 anrieXa UIT ml, pucroop. 38 MijexTIpatse: Aosmpame FHovata n spenerpeerero Ka TperHaKor rH axpeaysa BaumoT nOcrop 8p2 optoea rs Bauara Tenecea Tena w feparvcte mamaria Boobnaeua npenopavana s098 © 10 sna IU na von 12 aca, Sa sperma 8 cpuee yAap (ameapavjanen vecbapr) TBeGe AS MENTE Tovorva aoa on 3000 eve Xe IU wtTpawercn (oo a) 3 Tpernten va oapeners “nen a nr (apta Gonna) nexoT Clexene 2 yhorpa6yea co roubimaunaco enw (env on pony ra) gen ml (1 mi) oa pacracpor ae mermuparee Spun ron 10000 an Xo IU enorcanapi ‘AKO 080} fx ce saMeryse co aknwoerynaKmer nexooH KOH co naeaar ‘parvo, nerve no pea Aa co Npeca Depa TyRy no Moe eh, & 38 roa apente ce npmaet asara TpeTuara. Ova ozroeapa-1 spew nerpecno sTopvor Ne Aa "pawn extn v epeatociyie te roarynauyjere ta Gear eo pane kon co oxpedeut oh crpena ta Bauer rere. (sg Tp ‘ynorpeGe va Ciexane 20 rperian na coues yaap (wrap sebape) a) neuen va sospacr Maa 75 ron “aosava rpobea co Hauer va 75 ax Xa Why a cote 72 aca; oan naw” Mo TpoEd a, NPMMaT NoveTHE WeTpABeHCKa MAjeKLKja. ~“Hane wa anninaunja CLEXANE® ce nasa raKo nomomta (cyGxyTaHa) mjonunja, ocaeH Kora ce ‘nasa 2a ypeTaan Ha weoKspavjanen sMcapKT (80 To) enya) NOTPEGHO e owernara josa fa ce aninnyvpa werpaeer-ciorB0 Berd). He cweere na ro iexrupare Nexor verpamycxynro (80 myoxyr), @pexsenunja na annvxaunja Ce semaar nse vijeriwan Ha fen, 80 werpesan on 12 vaca ‘Tpaewe na tperuanor + AKO 'O npnware CLEXANE” 3a TperwaH Ha KpBAM arpyraysaita 80 ‘eniTe (BeHCKa rpow6osa), Bawara Tepandja Tpebs Aa Tpae Hejmory 10 neva: + Axo ro npwware CLEXANE" 32 Tperwan Ha onpegeH Tan Ha pasha Sonka rpermsior Tpe6a aa Tpae on 2-8 nena, ce Ao cTaSraMpaiee Ha Bawara cocoa; + Axo ro npiaTe CLEXANE" sa TperwaH a cpuee yap (snoKapanjanen 'nedbaprr) npenopavano speuerpaeise Ha TpeTwanior 88 jena win Ge AO anya va Goruara (fon npecTa wo Cant © noxparox 0 8 aera ro tpeda na ce npeseme wo cnyxa] Ha npeaoaupanwse na CLEXANE* 2 Bennaw rorracrapajre ro BauMoT nexap sepean praMoT On KpaApeNse, ‘AKo_umeme wexaxeu Gononwumenxu npawarsa eo epeKa co nexom ‘6pameme ce sa unibopwayuus Kaj Bauuom dokmop unu qpapmaueer. 4. MOXKHA HECAKAHM AEJCTBA HA NEKOT CLEXANE*6000 anti Xa 1U/0.6 mi, 6000 arrw-Xa IU/0.8 mi, 10000 awrw-Xa 1U/1 ml, actaop sa wijexrupaiue Kaxo u cume nexoau, CLEXANE woxe da npeCuseuKa necaKanu dejomea ‘aj nevou 00 moemupanume nauuens + Haasopewno mi sharpewko speapeke co pasnaven crenes Ha \cepwosHoct. Bo saKos cra) Tpeba aeaKa tpeSa aa ro wxpopupaTe Baunor nexap wn mequuuwcra cectpa. KpeapereTo NOME. fa © penwasuKaHO oA nesvja Koja KpBApH, Of saralyaatve va qhyHUjaTa Ha BySpeanre wm on HeKo) eK Ko) ro. seMaTa BO NETO speNe. CO ‘eroxcanapw *+ Hawanysatee Ha Gpojor Ha TpoMGouNTH KOE @o HKOM cnyvan @ MHIOTy ‘copaoaHo 12a Koo eednaw mpe6a da Gude useocmen Boxmopom KO) ‘Bu 20 e0du nnexyeamemo. Mopar Toa, 00 perynapnn speMencan epwons Tpe6a Aa ce nposepyea Spojor Ha TpoMGoUMTH: Mia MaDe 128 teapot sorewyeane He Gpjorva potas / + Bo perun cnysan ce jasyea Towa pearunja Ha Kowara Wa mecroro HA woe © aaqena unjensniara, { + YecTo ce jasyeaar moapmina win Hoayni (manh jaani) Kon Momel ia ce Nnosyecreysaar nog Komara Ha MOCTOTO Ha HijekTipaibe M KOM MOM £8pennscmaar paaniven creneH Ha Gonke, Oane esbec uoveanyaaar ronTano W He Ce pwsiia 2a nPeRAR Ha-TDETMSHOT, + Towa vis onus anepracis pear. + Pane oa ocreonopos (newmepannsauyja ka creneror Koja ja sronenyea cbpaniniocra Ha Kore) np npaROMKSH TPETHAH, + Boye epeci: SsroneMena acTusHoct Ha HeOM eHowNel He UpHNOT APOE BO KpETa, + sronemena Ha KoHUeHTp=Lja Ha KanHYM 80 xpeTa, + suawwTenen nopact va eoansocbarure (Geran KparinkneTa). Ova vacaKaHo ‘nejoTeo woxe Aa ce jasn MOMMpEHO UTM NpHADYEHO CO NOMEN Ha ‘+ Bo peti cnyvan una vapeuiran 2a Heapanowr npoBneM co pasnasia Teen oc one om Aaban0 ra OP 98 epee Fa Ho + Mviory perko vive wssewran 3a _anepricKn minyuRpaH socnanMTeTEH Ipousc 20 manure xpavi canoun ‘Ako saGenexume nojaea na neKoe HecaxaHo dejomeo, Be MonuMe Ba 20 lukcbopwupame Bawuom nexap un dapwauesm. Osa eu exnyyea u ecenanume dejomea Kou He ce HesedeH eo eHampeunome ynamemed. Hecaxanurme dejemea o8 nexom uoxeme Ga eu npujaeume u QupeKtmno eo rauuowanwuom yexmap 3a apuexosueunanta wae0don €0 AnenduKc B. Co Npujaeyearse Ha wecaxanume —dejemea npudowecyeame oa ce ounnemupaam nodamouume sa GesGedvocma 0d ynompeda Ha nexorn, 5. WYBAIBE HA TIEKOT CLEXANE*6000 auneXa IU/0.6 ml, 8000 anmw-Xa 1Ul0.8 ml, 10000 armi-Xa IU mi, pacrnop 2a mujertuparse Tlerom Ga ce syea na wecma Hedocmantu 38 Geuamal Pox wa ynorpe6a ‘Tlerom ne cee da ce ynompeGysa no ucmexom Ha damywam wa ynompe6a ‘mo e naeeden va nakyearbemo. Memexom Ha damyworn va ynompe6a @ 00 ‘mocnednuom GeH 00 aeceyom wim € HaBedeH Ha neKyearwemo, Hawn na syoarse na nexor cor ne ce yee 80 opyrmannor naxysaree Ha TelInepaTyps Ao 25°C. ncrpyayat 2a paryeaive co omnannner marepiijan Meammcor npowseogu He speGa aa ce oncrpanyesET pony Kakanmgeuvorara Mpexa ni co powaunror omen, Mpaulsre ro Baunor ‘apwaues karo qa ro onctpanare ormanHioT NareDHian on MeaMUNHCRATE Rpowseoay. Oave wepar nowaraar ja ce sauTATHTE ceOe cu mM BeusTa 6. ROMONKWTENHH HH@OPMALMH kro coapust CLEXANE® ‘Anmusna cynemanyuja: eroxcenapits HarpAyCClexano 6000 aumu-Xa 1U/0.6 mi, pacmegp 2a unjormuparse 80 npemxcoKo ‘anonuem wnpuy, Enon nperioano wenonwet unpruy og 0.6 mi vasa 6000 annexe IU (exoneanestrx0 va 60 mg enoxcanapm varpiny). Clexane 8000 anmu-Xa IU/0.8 mi, pacmeop 2a unjekmuparse 60 npemxodKo snanonwem winpuy Exes npevxonvo wanonmer unpriy of 0.8 mi viva 8000 anmuXa IU (exonsancrtwo na 80 mg enoxcanapm warpayi). CClexane 10000 anmu-Xa IU/t ml, pacmeop 22 unjermuparse 20 nponnxoaHo anonwem wnpuy. Ene npersoavo Wanonmer wnpru oA 1 mi wie 10000 awrXa IU (exonsanertH0 Ha 100 mg enoKcaraphe HarpryN), Tomoumu cyncmanyuu: Boga 22 worn armen Wa CLEXANE*H conpwonna Ha naxysarsero 0.6 mU0.8 mi/t ml pacteop 2a uxjextmpaise 80 nperxonHo Hanommer wnpwLs (Graknan), axyaaise: nytvja co 2 unpmua, Apowseoaures Zone Industrielle 70580 Le Trait France ‘Sanofi Winthrop Indust, 180 rue Jean Jaures, {94702 Maison Alford Cedex, France CCHINOIN Pharmaceutical and Chemical Works Peale Co, id aanyhveigy Ste Mishole, Csanyilvdiny 3540 Hungary Hocuren wa ogo6penuero 2a npomer Bo PenyOnuxa Maxenonja: CAHOOH-ABEHTUC Maxegorsja LooenCxonje, Amma Teta Ops, Cronje, Penynna Mavenonsia Hawn wa wopaoare locor waxe fa ce npimesyea camo 20 agpascreena ycranoea (3) Aavyw wa nocneawara peswauja Ha eHarpewNoro ynarcrao: ‘Syri, 2014 roma ‘5poj Ha opo6penne 2a npower:32 noyr# wicbopuatem go apexa co 080) nek, Be Monvate Kokanrupalre £0 HochTenor a OnoOperweTo 28 npoweT 80 PeryOnma Mansnorja ia ‘cneanior Tenedor: VHCTPYEUIAM 3A MEAMURHCKMOT NEPCOHAN Ynerpynuwn 38 ynerpeSa na nperxoqWo wanoneHTMor wnprtk co GeaGennocen wexanusand mncrpyrun 38 cy6KyranO MujeKrHparse Fiperxeaio HanoneveTwoT wnpuy © onpewen co apromerory SescenHoceH MoxaHvseM HaweHeT 22 npeBeHunja Ka cry\aiHa nospexa co urnara no ‘njexuparsero na pcraopaT. + Okcrpatiere ro saummvoro kanave of wrnara, florongy ua norpeSa, Npnnarogete ja qosara xoja ke ja wejecrupare. [losera TpeGa a cS Npwraroau 80 sasvoHocT of renecHeTa TaN na nauMeHToT. TpeA Ae ‘mjoxTupare wopa ga 10 opcrpariTe enwKOT of NeKOT Co HaCOHyEANS Ha unpouer ror one co npmTHcKatee Ha KAMNT. Ha OBO) Hatin Ke C2 Ccurypare fexa weypumeara on Bosayx fe OcraHar 0 LiNpWAIOT. AKO He ro onctpanie srwovor aR nexor GesBanhocnnor MexaniaaNe HeMa Aa Ce ‘axruaipa Ha spa} on anmuxauyjara. Locony wnpryor ja coapH Aosara oja Bue notpebka He ja weenayeajre nperxoanara nocrana, + Ha kpajor on venara woxe na ce nojasn kanke, Bo 080) enyvaj rpen na vwslentvpare rpe6a ga ja oncrpaniTe KannaTa CO HONDO TantaNee Ha lunpnucr (isiara Tpe6a pa @ HacoveHa Nagony) + Annueuvia Ha uMleKriara: nperxoAKo HananNerHoT uni e enpedreH ‘sa ynotpe0a: He TpeBa ga ce wcTucHyea eoanyx OA WNDMYET ned asareeTo He mjewuyjara. HajaoGpo © neKOT Aa My Ce Rasa Ma RayverTor “Bo nemewa nOAOHea, BO —NOTHOKHOTO THEO. Ha ‘anreponavepanisior ocTeponarepamuor CTONESH Si anrepramweno Ha nesaTa w va qecHara crpara. LfeneTa Aomwne He vara tpeba ja ce suece sepriman 80 Koxra, nA npse aron, Co HHexeio npimvcraive nowefy naneuor H noxexaneuor. He ja sHecyaaire lenara 30 xoxaTa HetoceHo. Koxara He Tpeba ja 8 ocnobonN ce ojera uenocvo He ce saspum vejerripawero. Mo saspulerara guarierpeunja wecToTo Ha mnjecTuparae He Tpaba na ce TpMe + BesBentocaor mexannaan c® axTMenpa aBToMaTeR Kora KRMNOT © enocHo npwmvowar im ja saummyea ynovpeSeHara rma Sed na ‘tbeawseica Henarogvocr Kaj nyserTor ‘BaGenewwa: SeaBeqnocuHor mexsnMsaM MONE AA C8 AKTHEHpA caMO OTKEKO fe ce memove Uenara conpiama of unpre.