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responsible for many of the sympyoms ,such as the fever, the flu-like symptoms,and the severe

pains.

In several incfection, the virus reproduction inside the body is greatly increased ,and many
more organ(such as the liver and the bone marrow) can be affectyed.Fluid from the
bloodstream leaks through the wall of small blood vessels into body cavity due to capillary
permeability.As a result ,less blood circulates in the blood vessels , and the blood pressure
becomes very low that it cannot supply sufficient blood to vital organ

Furthermore ,dysfunction of the bone marrow due to the infection of the cell leads to the
reduce numbers of platelets , which are necwssary for the effective blood clotting ; this
increase the risk of bleeding , the other major complication of dengue fever

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