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Organic Chem Cheat Sheet
Organic Chem Cheat Sheet
CLASS II
-
orgaEEEzggEtf
*Estes's . .
-
- i
- .
- .
- .
.
.
.
Bwesitnes
.
. .
Cayetana!one
1) Name Reaction . . . .
2.) Resonance . . . .
71
Organic Reagents $ Reaction means .
Price -
Just your support Is share
cahuf.mji ss.to'
Hame Reactions
a) ALDOL CONDENSATION :
CHS -
Cfo
+ H CH
-
,
CHO EICH, no .¥ocH5cn -
- en cao
-
cuz Ctf
- - - H .
IN H2 "
EE I Nat BE
fog ,
+
fluoro benzene
Aniline
d) BENZOIN CONDENSATION :
In die,
"
⇐ E- at takin
'
- -
,
Benzoin .
C) CANNIZZARO REACTION
CF Ona
:
LCH c'IH ) -
+ NaOH → CHGOH t H - -
I CHO + NaOH → -
CHIH tf -
COO Na
Benzoate
Benzyl alcohol .
Sod .
f) CARBYLAMINE REACTION :
-
NH + CHAZ -13 KOH calc )
Is NIC -13 KCI -13110
-
, .
g) CLEMMENSEN REDUCTION :
Nz tf
-
-
out HCl
-
NaCl + -
on
K hydroxy azobenzene
-
-
NaCl t -
NH
, E- Naff -
NH
,
p Amino azobenzene
-
¥442110
'
+ HOMO + HCl
iii. :%%%¥÷
k) :
"
¥,
o
"
..
Brown complex Benzaldehyde
Toluene
d) FINKELSTEIN REATION :
GHS -
Br + NAI ¥efA Gtf -
I + Na Br
my f- 17719 REACTION : pm
Init * EE
-
tenace
tense ¥7 ,.
a,
tudou.fi#EItHaAeephenone
O ) GAITER MANN REACTION :
Yau c>
[¥,Br+N4 cahuf.7iis.to
'
please subscribe
Cu¥
1- + N
2
b) GABRIEL PH TH AL IMIDE SYNTHESIS :
'
NH + KOH Nk t
GHS III
- -
'
Phthalimide pot .
phthalimide
Phthalic Acid
N phltralimide
-
Ethyl
Benzaldehyde
)
r H V. I REACTION C Hell Vol hard
.
Zelinsky Reaction)
Cte, OH tusked UCH OH +4 GCU COOH
,
Ck Red P
Cf C -
COOH e
,
R NH R TR X R pl R
# R NH, TR X ¥
H, NTR X - - -
-
- -
- -
R
t) HOFMANN BROM AMIDE DEGRADATION :
R CON Hg Es
R NH -12 Na Br + , cos -12110 Na
+
Big +4 NaOH
- -
-
CONH
,
+
By -14 KOH b- LIEN Ha -12K Bztkgcog -12140
U) HUNS DI ECKER REACTION :
CC 14
R COO Agt Bra R Br + cost
-
¥+7 -
Ag Br .
ona+co II.97
Na
,
> n'Ito >
icgiic Acid )
w) REIMER -
TIEMANN REACTION :
csalicyldehyde)
X) ROSEN MUND REDUCTION :
a
R - di -
U +H
,
Pd, Bash 's
>
R - d' -
H + Hes
Boiling xylene
SAND MEYER REACTION :
y)
del
El + Ha
Caa
→
Log fr
lol
t
+ Hbr ¥ A
Lot
CN
+ Ken
I) STEPHEN REDUCTION :
snag -12 HCl → snag -12 CoD
R CIN -12cm ) 1- HCl
-
# R CH -
-
-
NH.HU
ether
4
Boiling H2O
RCHO tNH4U
i) WILLIAMSON SYNTHESIS ,
R X -
+ R' ONA Y ROR
'
+ Max
( Hs I -
t ↳ Hs ONA
-
TCH, O -
-
GHS + NAI
ether .
KN NHL
-
KOH R.CH, N,
R CHO -
,
y +
glycol
CH
City COCH, "
y CHS -
Ctf -
,
"
>
- COCH
,
-
CH
,
CHS
iii ) WURTZ REACTION :
.IE#.aiiIII-::r-e7nerrr+2NaxCHsi:B..ir.II-
't
r
Denker iii.EIB.
CH, > Cates t2NaBr
iv) WURTZ -
FITTIG REACTION :
CHS Et tanar
III.I .is 1¥
-
>
cus
Toluene .
cahuf.mji ss.to'
# 02 . .
RESONANCE
\,
a
Positive Resonance
×
Resonance
Negative
↳ -70
µ
↳
a
.
IET
directing
directing
ROADMAP # 01 ( DIAZONIUM SALT)
que
Halwa
-7 °H phenol
In
X Hspoz
- > Benzene
cul HCl
> ¥, chlorobenzene
Ga Hermann Rx
4¥
y
CUMBO Bromo benzene
y
¥4
'
¥, Benoni bile
:÷÷÷÷÷÷ ::O::::* ..
niemann
1¥
"
-1¥, Thio phenol
9mg >
,
on ,
-
Ns -
9
→
Azo Due
coupling Rxh
,
AROMATIC CONVERSIONS
Sh .HU a
4102
Nitrobenzene
Loy SGH
+ A
>
Benzene
HMOs sulphuric
, got Acid
Hr
ninth Mask
FOCH , fHzCHs
FT CH Cl X 2h Hg X
"'
-
44
,
aniline ¥644
Benzene
ROADMAP # 03
CHS
Cl
Toluene
←E
fi
,¥u ,÷7aw
chloro
Biphenyl benzene co)
an
I
.me#:eEtiCHzU
IoT
can a
phenol Bennie
Benzene
×
CN y NAU'd
(
1- Benzyl
coal Ht
,
HP ) o l chloride [ o)
l l X
^ '
ou
-
Benzo AG KOH -
o, is
Hu Nitrile
CHIH CHO
Benzoic a
,
Acid
h
NH lol
, ,
X
1-
lol
x Benzyl Benzaldehyde
Beneamide alcohol
ROADMAP # 04
÷ i÷ ÷ : ÷ ÷ :t .÷ f:÷ : ÷ ÷
- -
zy.sk
X I ONA
Br NaOH
ou > Sod .
I
1--
Nor 104 phenoxide
a dit O
/
( #
.
o t ←NO
Naz Cruz 11
X H
, y
'
Nou Hasog Quinone
11
°
OH NaOH,
:÷:÷:*::
( picric Acid )
phenol OH
pm NaOH , CHCH ,
ACH, 104 CHgU ↳ CHO
c- →
,
x
14
+
lid '
Anny at ¥ salicyldehyde
CH, Mlb Zu a
+ ZnO
Mth NH. A
7
X 5-
Benzene
lot on
+ BBK
>
BK¥B8t3HBr
-
875.7 's!'
; i
Br
↳ 94,6 Toibsomo
ROADMAP
-
1¥ , R CHON
-
R CHO
-
R COOH
-
→
Alcohol Aldehyde
R -
MHz
X
R MHz Boz , 4 KOH
-
c- R CONH
-
Amide
R CH 99¥> R
-
,
-
CHL -
OH -
R -
CH
, Co]
oxidation
R -
H NaOH co]
5- R Cooma -5 R COOH f- Reno
- - ←
Naou ,
aldehyde
Cao
#
ROADMAP # 06 Step Up .
R H
-
+ By his R Br
- Ni ,
R R
-
Amane
Wark RM
1¥ ,
R I
-
¥ R CN
-
"-7 RCONH,
R OH-
Rayon
HOMO
← R CH -
NHL
"°" Ht
,
,
tho
1-
"
243 Heat
RCHO 1- R COOH
-
e-
Reduction .
Cal Salt
.
,±% ¥oni"
""
ROAD MAP # OF
-- asana.
EE
←
let 's
nao
-
Benzene
1.
, ,
t.CO HCl
PUS
Has04
,
( Cleo CON Hz
1-
Benzaldehyde
i
,S0sH
e-
Benzene Sulbhonic Acid
NLU NH
f. NaOH fuse ,
"
cah.eu?iiss'?o '
# 04 .
Test To
Distinguish .
* How will
you distinguish b/w propanol and poopanone
Propanol Psobanone
Iodoform
Test GHz OH + Int NaOH + NaOH
(
Hzcoctfz +
Iz
-
-7 No RM
y CHI , + CH, COON a
Yellow ppt +110 1- NAI
Ethanol Phenol
Iodoform GHS OH -
1- Ist NaOH 04+5<-1 NaOH -3
Test
→ CHI + HCOONA No Rxh
,
.
+ NAI -1110 OH
Bra water ↳ Hs .
-
OH ¥ No white + 3Brz→B Br
Ethanol Propanol
+ 3NaI
+31120
*
Distinguish b/w Penton -
2- one $ Penton - 3- one
+ Had + NAI B CU Ig
.
cahuf.mji sst.io'
M -
Iab .
¥ How will
you distinguish b/w propanol $ propanone
Propanol Probanone
Iodoform CH, Chacko +Iot NaOH CH, COCH, +Iet NaOH
Test 0h19
→ No yellow Ppa →
CHIZT CH
,
+ tho + NAI
cH3CHaCH0+2EAgcnHgz3t
.
Totten 's
Reagent
CHZCOCH, T7
+30N
-
Test CH
Chefoo Engle Reagent
-
→ , + ,
CHgcoctgfehliys.tn >
Test →
ctegcteucoo +
Cayo -13110 No Red
-
Ppf .
( coats )
Iodoform
CHO + NaOH + In
fest
-
Cock
,
+ NaOH + Iz
→ No yellow ppt → CUI t - Cooma
,
+ tho + NAI
AGNO ,
→ Totten 's
fest G- Cho
R¥ -
¥ Acetophenone ( Ey -
COCH, ) and benzophenone ( Iof -
co -
GI)
Iodoform
- COCH + It NaOH CO -
TIL + NaOH
Test ,
→
CHIS t Cooma → No yellow ppt of
+
Hot NAI CHIS
Toqkgn
HOOH-IICASCNH.ldttdon.CH, on ten
Reagent
→ I Agt, + COELHO -14Mt No silver
Mirror
1¥ Benzoic Acid ( Iof Coon) and Phenol C - OH )
man
:p, iii. nano
.si:7?::inEi5n:::9.wi .
Coon of CO2 .
Feels 3C ) + feels → OU
Test H Violet
¥ + feels →
(Foy Coo
}fet3HCl colouration
1¥
. Methylamine CCH, NH, ) and dimethylamino CCH ,
NHCH, )
, , ,
,
→ ⇐ SO ,
-
N CH, )kttH, O
-
insoluble in
as
Soluble in Kon →
ag Kon
. .
Ans .
packing
is be Heo in solid form Hence it has .
stronger
intermolecular force of attraction than o - and
m -
isomers .
cahuf.mji sst.io'
Alkyl halides though polar are immiscible with water ? .
than
energy released by water halide interaction .
¥493
AI Ih chlorobenzene bond has
'
Esb C a -
Na SOLUBILITY OF ALCOHOLS
solubility of alcohols is water
is due to their ability to form hydrogen bond with water
molecules The
solubility
. decreases with increase in
size of
alkyl groups and solubility increases with increase
in branching the order is 1k£53 .
"
R
> CHOU T
go
RAI C- OH
30
extent due to H -
Bonding
-
solubility decreases with increase in Mol Mass .
-
Ethers are fairly soluble in all
organic solvents
such as chloroform ,
alcohol , benzene etc .
1¥ SOLUBILITY OF PHENOLS like alcohols ,
phenols are soluble
in water due the
formation of
with
µ
bonding water
-
.
-
Phenols are less soluble than alcohols due to
I#
Boiling Point much
higher than corresponding hydrocarbons
and haloarenes intermolecular
due to H -
Bonding .
Point of
⇐
Boiling Aldehydes and ketones The B.pt of aldehydes and
ketones are higher than hydrocarbons and ethers of
comparable molecular mass due to weak dipole
-
dipole interaction .
Their
-
isomeric
Among aldehydes and ketones ketones
-
I
Solubility of aldehydes and ketones
lower members of
aldehydes and ketones Cibo C Ce) are soluble in water due
to H -
-
Aromatic aldehydes and ketones are much less than
corresponding aliphatic aldehydes and ketones
due to larger benzene ring .
Ea
solubility of carboxylic Acid
-
of
carbon atoms Higher carboxylic acids are practically insoluble
.
-
-
Benzoic acid ,
the simplest aromatic
carboxylic
acid is nearly insoluble in cold water .
cahufnfiisst.io'
Point of Acid
E.
Boiling carboxylic
have
carboxylic acids
higher B.Pt
than aldehydes ,
ketones and even of comparable molecular mass
due to more extensive association of their molecules through
intermolecular completely
H -
Bonding . The H -
Bonds are not broken
even In their vapour phase .
Primary and
secondary amines are soluble
in water due to H -
I
effect of aryl group
-
-
-
In
gaseous phase ,
the order of basicity
3. amines > 2 amines > co amines > NU,
-
In
aqueous phase ,
despite of inductive effect solvation
,
(
Katy:3 NH
)
Cq
.
Hs)
,
NY GHS -
7%1,1
10
and
(CHD GNU , NHUT (CHAN > NHS
*
°
z
.
cahufnfiisst.io'
HE
Aryl groups are more acidic than alkyl groups .
✓
FE Electron
.
withdrawing group
increase -
I effect hence
increase acidic strength
acidic and decrease basic
ka x
strength strength .
Oxidising
Agents
.
# ORGANIC REACTION MECHANISMS
SNL
i¥±
.
stop
Acid rk#
catalysed
Hydration
of Alkenes .
Dehydration of Alcohol
lfthlkene tethers .
gag
Nucleophilic
Addition
Reaction . . .
*
BIOMOLECULES
CARBOHYDRATES Tahfisfeapoeunanixjdl '
cellulose
Cyclic
Ring
.
.
PREPARATION OF GLUCOSE
Dimmitt W
From sucrose
bharat panchala ,
#
"
or Kebnic
(61%05) n t n H2O n (6111206 ( Reduce
group
Glucose )
rehling
-
({ HOH)4
Non
Four alcohol
Reducing Sugars
← 20
Do have free
-
not
CHEMICAL aldehyde or ke tonic
PROPERTIES OF GLUCOSE Do not gp .
Rehling
-
Sucrose
Reagent .
PROTEINS
These are the biomolecules from which
living system
"
made up of .
"
These are the polymers prepared by the
monomers of A amino acid
by condensation polymerisation
-
R -
fi -
COOH
E
R Coon COO
-
- -
R - -
i
CHO CHO
NH ¥ NHI
1-
,
TH
,
H OH HO
Amino acid twitter ion
① means -
OH in L US -
{%osywM
E. CLASSIFICATION OF AMINO ACIDS
→ ON THE BASIS OF SOURCE
Essential amino acids Nonessential amino acids
which can't be synthesized in Which can be synthesised
body in the
the and must be supplied body .
}
diet
through .
Equal of
no .
amino More no .
do More no -
of
and Carboxyl group amino
carboxyl gp .
groan .
e.g Glycine
.
Alanine ,
e.g Aspartic
Acid ,
e.g lysine ,
#
PEPTIDE BOND Peptides are further divided into di tri tetra
when two L -
amino acids combined , ,
together to form peptide by the elimination of depending Ubon the number of 2- amino acid combined .
water .
the bond CO NH -
.name. . . . . .
The pH at which dipolar
ion czwi Her ion ) exists as neutral ion .
ie-
+ re
and is
+ >
-
ve
charge equal and it does not
migrate
iii.ii. to either electrode is called isoelectric point .
Primary Str Secondary Str
NUCLEIC ACIDS
.
.
chain exist
polypeptide also called poly nucleotides
cyclin .
sty of .
Ci ) x -
helix
1) A)
Deoxy ribonucleic acid CD.nl
bleated
.
" fibrous
cii , globular subunits w -
rt each
other
1.) Pentose sugar 2.) Phosphoric Acid 3.) Nitrogenous base
In DNA is In RNA, is
sugar present sugar present
• •
2-
p D deoxyribose D ribose
-
B
- -
-
mm*
DENATURATION OF PROTEIN
A protein found in
biological system with a
unique #
INDimmitt
•
a
3- D Sto .
but I
.
sir.
remains intact
of white
e.g coagulation egg boiling
. on
curdling of milk .
I
GLOBULAR PRO TIEN FIBROUS PRO TIEN
They have nearly spherical have linear thread
1 . y
* They
structure . like Str .
* insulin e
,
albumin ↳ Keratin Chair ,
wool , silk)
myosin ( muscles)
§
parts of cytoplasm
synthesised synthesis
ptooteibosgymnesmdesY.fi ng
-
STRUCTURE OF DNA : -
t a
DNA has a double helical
G c
structure with ACT
T A and 90C linked together
j✓¥
9 c
at Ac hydrogen bond
respectively .
D.o@umMn.M
"
T A
q c
&