FAQ For NBMI-OSR-Irminix-Emeramide

FAQ for NBMI/OSR/Irminix/Emeramide group | Facebook
David F Morrison
FAQ for NBMI/OSR/Irminix/Emeramide group
6 DE SEPTIEMBRE DE 2019 · IRMINIX / NBMI /...
Copyright © 2019-2020 Admins of Irminix/NBMI/Emeramide/OSR Group
Many questions have been asked in the group over the last few years. The answers to many
of them have been compiled into this FAQ for the group. It is not going to answer all
questions, but it should provide some background and answer the most common questions.
Newcomers should be referred to this document.
Why is this document here?
NBMI can potentially be dangerous. The descriptions in this FAQ are a considered and
conservative approach, suitable for beginners so they do not end up hurting themselves. The
answers are a distillation of many threads and comments from experienced people.
When people ask questions, the answers can be very variable. Some people give one word
answers that do not explain why they think it would be useful. Others are very adventurous
and advocate radical approaches that they may have tried themselves. Yet others repeat
what other people have said, not always correctly.
THERE ARE NO DEFINITIVE ANSWERS ABOUT ANYTHING TO DO WITH NBMI/OSR.

YOU MUST DECIDE FOR YOURSELF BASED ON YOUR OWN
READING/UNDERSTANDING.
The important thing is that everyone's experience is different. What worked for one person
may not work for another person. We do not want people ending up doing something they
regret.
If you are having serious health issues like heart irregularities, or have long-standing
complicated health issues, GO TO A HEALTH PROFESSIONAL.
By joining this group you acknowledge that the content is for informational purposes only.
Nothing said here should be considered as medical advice and does not in any way replace
the advice of a medical professional. Opinions by other members are theirs alone. Members
must use their own judgement regarding any supplement or therapy they choose to use on
themselves or others.
Members who offer health advice need to be aware that they are taking responsibility for the
life and health of other people. There is even the possibility of being sued in some
jurisdictions. We recommend that people stick to relating their own experiences or answering
questions factually.
Terminology
Sulphur, sulphate, sulphite and other forms are often spelled sulfur, sulfate, sulfite, etc. They
are the same thing.
mg is short for milligram. mcg or ug or µg are short for microgram, one thousandth of a
milligram. Do not get them mixed up!
Recent updates to the document are shown in italics.
What is NBMI (also called OSR, BDTH2, Irminix and Emeramide)?
NBMI is a chemical discovered by Boyd Haley to be an excellent chelator of some heavy
metals including mercury, lead and cadmium. It has been suggested that it will also chelate
arsenic, free copper and free iron. It does not affect aluminium. It is also believed to affect
levels of other minerals like zinc.
It was sold as an antioxidant (OSR#1) for four years about 10 years ago.
Study discussing use of NBMI as a mercury chelator:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346673/
In human trials there have been no serious side-effects (ie, requiring a visit to a doctor or
hospital). Experiences in this group have shown a variety of minor side-effects - see below.
The major advantage of NBMI over other chelators is that it binds permanently to mercury
and some other heavy metals and inactivates them. Once inactivated, the metals can do no
harm even if they hang around in the body for some time.
Which metals does NBMI/OSR bind to?
Steven Fowkes says this: NBMI binds to metals differentially based on their size and affinity
for sulfur. Most nutritional minerals like chromium, iron, zinc and copper are first-period
transition metals (the first transition metals row on the periodic table of the elements), to
which OSR has only transitory affinity (as stated by Boyd Haley). OSR's highest affinity is for
the toxic-only, third-period transition metals (mercury, tungsten, gold) and their higher-weight
heavy metals (lead, bismuth, uranium, thorium). These are "larger" and "softer" (in chemical
terms) and fit OSR well. In between are the second-period metals, of which molybdenum
and cadmium are examples. These might have an affinity for OSR that is intermediate
between the first-period and third-period metals. You'd want to get rid of cadmium, but not
necessarily molybdenum. So my suggestion would be to take any molybdenum
supplementation opposite your OSR. I have no factual basis for that suggestion, but merely
a prediction that further research may identify an OSR-moly relationship that is unique.
The June 2020 issue of the Emeramed newsletter says:
“Studies on metal binding have shown that NBMI is strongly attracted to Mercury, Arsenic,
Lead, Cadmium, Uranium, Gadolinium and free iron and copper. The unbound (free) Fe2+
and Cu2+ redox metals are produced when toxins that induce oxidative stress are the cause
of illnesses.”
This implies that NBMI may chelate any of these metals.
https://emeramed.com/newsletters/emeramed-newsletter-june-2020
Stephen Fowkes expands on this in this post:
https://www.facebook.com/groups/1359748427477127/posts/3145347555583863/
What about titanium implants (plates, screws, etc)?
“Titanium is not a heavy metal and would not be targeted by NBMI.”
https://www.facebook.com/groups/1359748427477127/permalink/2336276986490928/
How can I tell if I have a heavy metal problem and how bad it is?
There is no definitive way to determine if you have a heavy metal problem, although it can
be inferred in a number of ways.
1. Exposure
If you have been exposed to mercury or other metals during your life, you may have raised
levels. This could be through your workplace (eg, lead smelter), an accident (broken
thermometer or fluorescent tube), having vaccines with mercury preservative, use of
mercury-containing antiseptics (mercurochrome), having amalgam fillings in your teeth, and
eating a lot of seafood, especially bigger fish.
2. Blood test
If the metals are mobilised, they may show up in a blood test. Metals can be mobilised
through recent exposure (eg, having amalgam fillings removed unsafely) or use of poor
chelators such as cilantro/coriander. Blood levels will usually decline with time as the metals
get deposited in different parts of the body. Mercury, for example, will often end up in bones,
the brain and the kidneys, so even if blood levels are zero, you may still be carrying a lot of
mercury.
3. HTMA test
A hair test can show levels of excretion of various metals. The actual levels for an individual
metal are not always meaningful, but mercury can cause dysregulation of metal handling
which can suggest that mercury is a problem. Andy Cutler devised a way of interpreting this
so as to identify if mercury is likely to be a problem.
The recommended hair test is the Doctor's Data Toxic and Essential Elements test. Note that
DD has a Toxic Elements test which is not adequate.
This test is normally available only through practitioners, but there are other ways - see here:
https://www.facebook.com/notes/irminix-nbmi-emeramide-osr/where-to-get-doctors-data-htm
a/2545150838936874/
The Cutler Counting Rules are an ad hoc method used to analyse the results. This is an
older version than the current rules, but seems to give pretty much the same result.
https://web.archive.org/web/20180605111514/http://home.earthlink.net/~moriam/HOW_TO_h
air_test.html
Is NBMI/OSR safe to use?
NBMI has not been approved for human consumption yet, although it is expected to be
some time in the next few years. People who take it have a risk of negative consequences.
There may be side-effects, some quite distressing - see below.
In some cases, the reactions may be anaphylactic, ie, severe allergic response which can be
life-threatening. Please read up on anaphylaxis so that you can recognise it immediately and
take appropriate action.
https://en.wikipedia.org/wiki/Anaphylaxis
If you are not comfortable with this risk, please do not use the substance.
What side-effects can occur?
See Sam Vimes' collation of information from Yahoo groups from when OSR was available
as a commercial antioxidant.
https://www.facebook.com/notes/irminix-nbmi-emeramide-osr/information-collated-from-yaho
o-groups-on-osr-by-sam-vimes/2232762273509067/
People with Lyme or similar diseases may experience die-off when they start NBMI. Start
slowly to manage the symptoms.
This thread discusses some of the side-effects people are experiencing now.
Note that side-effects may not appear immediately. They may take several days to develop.
For example, chelating metals can cause a histamine flare. This takes some time to build up,
so the symptoms may take 2-3 days to appear. For example, if you take NBMI on Friday
morning, by Saturday afternoon you may have a couple of hives (red lumps on the skin).
More may develop on Sunday, and they may become more itchy. The itchiness may last for
several days.
This is why the recommended way to start is one dose every few days, to allow these
delayed side-effects to become apparent. Starting with doses on consecutive days will make
any flare-up worse and it will last longer.
But Boyd Haley said there are no side-effects?
Firstly, he is referring to “significant” side-effects. These are side-effects so bad that the
person goes to a doctor or a hospital for help. Most side-effects reported in the group have
not been that bad.
Secondly, NBMI is made using chemical solvents, and tiny traces of the solvent may remain
in the powder. Sensitive people - and many of us are sensitive - may react to the traces of
solvent, rather than to the NBMI itself.
Is there anything that indicates I should not take NBMI?
1. Boyd Haley was quoted at one time to have said that people who are allergic to Sulfa
drugs (certain antibiotics and other drugs) should avoid all compounds that are high in sulfur,
including NBMI.
Discussion in the thread below suggests he was actually referring to enzyme pathways, and
that Sulfa drugs are not involved with this pathway.
The implication is that allergy to Sulfa drugs should not cause any unpleasant reactions
when taking NBMI. Later in the discussion, several people state that they are successfully
taking small amounts of NBMI despite having a Sulfa allergy.
Nevertheless, please familiarise yourself with the symptoms of allergy so as to recognise it if
it happens to you. Severe allergic reaction can be life threatening. Signs include rashes,
itching, chest congestion, swelling of the mouth and throat and anaphylaxis.
https://www.healthline.com/health/sulfa-allergy
2. If you have reactions to thiols, NBMI may cause similar reactions. Thiols are a family of
chemicals based on sulphur and are common in many foods.
List of high thiol foods compiled by Andy Cutler:
https://web.archive.org/web/20180623092310/http://www.livingnetwork.co.za/chelationnetwo
rk/food/high-sulfur-sulphur-food-list/
If you have problems when you eat a lot of these foods, you may have a thiol issue.
3. If your digestive tract is not working well, especially with poor motility or constipation, fix
this first!
NBMI is excreted through the liver into the gut as bile. This mixes with the food you eat and
is eventually excreted as stool. If you are constipated, the stool will stay in the gut for an
extended period of time and potentially allow various substances to be reabsorbed. NBMI
with its heavy metals may be reabsorbed, although it should not do any harm.
See the question below about gut health for more on this.
Are there any guidelines for treating children, eg, with autism?
There are some parents in the group using NBMI with their children. Look through the list of
Topics in this group for #autism.
A fellow called James Kendall has set up a Telegram group for parents dealing with issues
for which NBMI might be helpful. This is his profile:
https://www.facebook.com/.../13597484274.../user/1062385346/
Send him a PM and ask to join the Telegram group.
What can I do to help the process?
1. Detox pathways in the body often require reasonable levels of sulphate. Mostly we get
sulphates from food:
http://apjcn.nhri.org.tw/server/info/books-phds/books/foodfacts/html/data/data5g.html
Sulphate levels can also be improved by epsom salt baths or foot baths.
2. The body will be working hard to eliminate the mercury, and some supplements can help
the body cope. Take plenty of magnesium, a multimineral, vitamin B complex and vitamin C.
Remineralise after exercise with an electrolyte drink.
With ACC chelation, it is recommended to take the “Core 4” supplements while chelating.
They include Vitamin C, Vitamin E (mixed tocopherols), Magnesium, and Zinc – all in
significantly higher doses than the daily recommended allowance. For NBMI/OSR, these are
not strictly necessary, but are unlikely to do any harm if taken away from the NBMI.
3. More information on Detox Pathways:
A few links that review Liver detoxification pathways, Phase 1 and 2.
Briefly, Phase 1 breaks down compounds entering in from food. Xenobiotics are exogenous
(foreign) compounds, ie toxic to human health. Examples are: metabolic end products,
microorganisms, contaminants/ pollutants, insecticides, pesticides, food additives, drugs and
alcohol.
While cytochrome P450s are found throughout the body, a majority function in the liver. The
required nutrients for Phase 1 are: B vitamins, folic acid, glutathione, anti-oxidants,
carotenoids, Vitamins E (mixed tocopherols) and C. Taking selenium helps Glutathione
anti-oxidant processes.
Phase 2 converts Phase 1 products so they can be excreted as water soluble waste
products. The required nutrients for this pathways are: the amino acids glutamine, glycine,
taurine and cysteine as well as sulphurated phytochemicals found in garlic, and cruciferous
vegetables (broccoli, cabbage, cauliflower among others). Molybdenum supports the
conversion of sulfites (toxic) to sulfates which are water soluble.
When Phase 2 is completed the waste is eliminated via two routes: 1-gall bladder to bile to
bowels and 2- kidneys to urine.
Are there multiple types of NBMI and are they safe?
NBMI is a single substance that can be made in a number of different ways using different
solvents. Some solvents are believed to be safer than others, although the concentrations of
all are way under the safe levels for humans - see next question.
A number of people here have arranged independent testing to verify that the substance is
what it is supposed to be, and to determine the level of purity. The purity is generally much
better than 99%. Results of the testing are often posted to the group and can be found by
searching or in the Files area.
Are solvents used to make NBMI? Does the solvent make any difference to the effectiveness
of the drug?
Manufacture of chemical substances often uses “cleanup” solvents to purify the products,
and tiny (less than 0.002%) residues of these solvents may remain in the product.
Sometimes even these tiny amounts can cause problems for sensitive people.
Early versions of NBMI from Fandachem were made using a solvent called dichloromethane
(DCM), but later versions used ethanol (or ethyl alcohol = EA) as it is considered safer.
Ethanol is alcohol as found in beer, wine, etc. EA should not leave any residues in the body
whereas DCM may. While many people have had good results with the DCM version in the
past, some people have had problems suspected to be due to solvent residues. It is now
considered that the EA version is the best to use.
Medkoo uses dimethyl foramide (DMF). There have been no reports of problems for this
solvent.
My NBMI is fairly coarse. Does this make a difference?
Some batches have been a finer powder than others. It is thought that a finer powder may
be absorbed better. Some people grind it into a finer powder before using it. This is more
relevant if you are using it transdermally or swallowing with oil. If dissolved in DMSO before
using, the grain size is irrelevant. See below for more on DMSO.
This post reveals an idea for using DMSO to reduce grain size instead of grinding. This may
make NBMI more easily absorbed.
https://www.facebook.com/groups/1359748427477127/permalink/3794281340690478
The Emeramed web site says that there is counterfeit Irminix being sold by other suppliers.
Is the Fandachem and Medkoo version counterfeit?
The Emeramed web site says: “Counterfeit Irminix® is being sold under our various trade
names (OSR#1®, NBMI, Emeramide) and tests have shown that it is not Irminix®. Irminix®
may be available in your country in compliance with various regulations through our Early
Access Programme.”
The chemical name of the substance is BDTH2. Emeramed is being legalistic here. It is
complaining that companies are using Emeramed’s proprietary names for their own version
of BDTH2.
The suppliers mentioned in this group supply a product identical to the Emeramed product.
The substance is independently tested by members of the group to verify that each batch is
what it says it is, and that there are no contaminants. Test reports can be found in the Files
section of the group and by searching the discussions.
PLEASE TYPE THE WORD “OSR” IN THE COMMENTS TO VERIFY YOU HAVE READ
THIS.
I have an upset gut/arthritis/itchy skin/brain fog/etc. Will getting rid of mercury fix this up?
There are some conditions that affect people who are mercury toxic, but also affect those
with no mercury problem. While mercury may make you more susceptible to these
conditions, relying on eliminating mercury is unlikely to fix them by itself.
There are two things to note. Firstly, eliminating mercury is a long term process. Expect to
take at least a year, and probably several years. Do you really want to be suffering the
condition all that time?
Secondly, the fact that non-mercury-toxic people get the same conditions indicates that
maybe mercury is not a significant factor. This means that methods that other people use to
deal with the condition may help you too.
So, for example, if you have gut problems, you may want to look into methods to help, such
as changing your diet, taking supplements, taking probiotics or prebiotics, etc which may
give you immediate relief.
Note also that many conditions have been shown to be gut related (eg, arthritis, eczema).
The gut is also the main way to get the mercury+NBMI/OSR complex out of your body, so it
needs to be functioning properly just to get the mercury out. Looking after it should be a first
priority.
There are sections in this FAQ about improving gut health.
How do I take it - oral?
It is fat-loving so should be mixed with fats like ghee, olive oil and coconut oil.
Most swallow it while others place it under the tongue. In the latter case, some people
dissolve it in a few drops of pharmaceutical grade DMSO, then mix with oil.
How do I take it - transdermal, ie, through the skin?
Mix it with oil and rub on the skin. It would be desirable to have a fine powder to make this
more effective. Larger granules are likely to result in poorer absorption. Boyd Haley says it
dissolves well in emu oil.
Some people dissolve in DMSO, then mix that with oil and rub on the skin. Read about
DMSO and its risks below.
How do I take it - other?
One person is experimenting with putting it in a nebuliser and inhaling it that way.
Can I dissolve NBMI in a solvent to improve absorption?
The only thing NBMI is known to dissolve in is DMSO (see below). Even though the
Fandachem product is made with ethyl alcohol (EA), it is only used as a cleanup solvent to
remove remaining impurities and NBMI does not dissolve in it.
What is DMSO and should I use it?
DMSO is a liquid solvent produced as a by-product of the paper making industry, and is
considered a neurotoxin. Its main feature is that it penetrates the human skin easily, carrying
anything dissolved in it into the body, including things like medicines, toxins and skin
contaminants like make-up or sunburn cream.
It has been suggested that dissolving NBMI in DMSO would allow it to get into cells better.
This may be helpful for transdermal use (ie, rubbed on the skin). There is no evidence of any
benefit from taking it orally, and there is potential for some harm, such as burning of the
mouth and throat.
Kristina Hines has looked into use of DMSO in depth and concludes: "Many of us thought it
(OSR) probably needed help to get where it needed to go in the beginning so we tried taking
it with DMSO. In the end, I did not feel it was necessary at all. OSR gets where it needs to
go just fine on its own without the DMSO."
DMSO is potentially dangerous, and should be thoroughly researched before contemplating
its use. If it is used, only pharmaceutical grade should be used to minimise any dissolved
toxins.
What time of day is it best to take NBMI?
The experience is that some manage better in the morning as they have more energy after
they take it. For others, it makes them tired so they take it at night. You may need to
experiment to see what is best for you.
Is there a significant benefit from taking two or more doses a day?
Most people take it once a day, but some spread it out over the day.
How much should I take?
Ideally, an adult will be taking around 300mg per day. However, starting at this level can
sometimes cause severe side-effects.
Current experience within this group is to start with a small amount at intervals to identify if
there are any side-effects. If there are no side-effects, or after the side-effects have settled
down, gradually increase the dose.
If you are quite sick or think you are very mercury toxic, a reasonable amount to start with is
3-6mg every 2-3 days. Taking NBMI every day intensifies chelation symptoms.
By taking it every 2-3 days to start, you will get an idea of how it affects you and allow any
symptoms caused from NBMI binding mercury to settle down. Sometimes, eg, with
histamine sensitivity, the symptoms may take 2-3 days to appear, and take anything up to a
week to go away. In this case, hold off the next dose until the symptoms have settled.
Continuing to take NBMI will only intensify the symptoms.
If that is tolerated without too many side-effects, try more often, say every second day then
every day, then twice a day. Only when you can tolerate this, increase the dose SLOWLY.
People have had to stick to low doses for several months before being able to increase the
dose. (Thanks to Aron Aron for this.)
Here is an example of someone taking a large dose initially, and suffering bad effects for
years afterwards. The dosing schedule here is designed to allow people to discover their
level of tolerance without making themselves very sick. If you have no reactions after a
couple of weeks, you can increase the dose fairly rapidly to the recommended amount,
always monitoring reactions carefully.
There are often questions about whether larger doses than 300mg are helpful. Some people
say they can feel the difference. However, this post quotes Dr David Kennedy, one of the
scientists working on the trials. His view is that the body cannot use more than 300mg per
day.
This is a substance that can make you feel very sick. Always be cautious. Clearing yourself
of heavy metals is an endurance event not a sprint. As much as you might want to be rid of
the metals, go low and slow.
Is it still effective taking only small doses?
Yes it is. Chelation will ofc be slower but you should still make progress. Read this thread for
an example of how this works.
Approximately how long is the average treatment duration? I know it will vary by case, but I'd
like to have some sense of how much I should order.
The time is largely dependent on how much mercury is in your body, and how rapidly you
can chelate it. Some people have to start with the tiniest amount, eg, 3mg, so 20g will last a
long time until they can build up their tolerance. otoh, others can get to 300mg fairly quickly
in which case 20g will only last 60 days.
Unfortunately, there is no way to predict whether anyone will tolerate large doses or not. You
have to try it and see.
As for time, I think one person said about two years for them, but this was after a couple of
years of Andy Cutler chelation.
What actually happens when I take NBMI/OSR?
When NBMI binds mercury from a mercury-damaged protein within a cell, that process
causes cell damage and the body responds with an inflammatory response to repair itself.
Many people feel increased pain, especially joint pain, but those symptoms normally resolve
for most people within 2-3 days.
In some people who struggle with low metabolism, the above process causes increased
adrenal compensation. It is your body’s stress response.
With an autoimmune condition you can take immune suppressants like low dose naltrexone
which are quite safe to normalise the immune system. It just depends what else is going on
and how bad it is.
An overactive nervous system is also very common with mercury.
Do I need to take precautions before using it?
1. Can NBMI be taken safely while there are still amalgams in the mouth? This is not
recommended in some other chelation methods.
Yes
2. Do I need to use binders to mop up mercury when taking NBMI?
No. NBMI grabs mercury atoms permanently, so they are never left floating around for a
binder to act on. However, some people do take binders. Beware that binders can cause
constipation which should be avoided at all costs.
3. Do I need to use ALA/DMSA/DMPS while taking NBMI?
No, although some people do take them. (ALA, DMSA and DMPS are substances used in
the Andy Cutler chelation protocol.) The idea is that they may be better able to release
mercury from where it currently is, so that NBMI can grab it. It is not yet known whether this
has any benefit. One member tried an extreme experiment along these lines and felt great
for a few days, then crashed with serious mental health issues which took a long time to
overcome. Be very careful!
4. Since NBMI will grab on to minerals other than mercury and lead, should mineral
supplements be taken away from when NBMI is taken? (Thinking of magnesium, potassium,
lithium, molybdenum, etc)
Yes. NBMI can potentially lower levels of these minerals in the body. Taking them at the
same time as NBMI may lead to the NBMI attaching to those minerals instead of to the
heavy metals, reducing its effectiveness.
Two approaches have been used. In the first, the NBMI is taken in the morning, and the
minerals are taken 12 hours later. Given that NBMI takes 23 hours to drop to half strength in
the body, it is almost certainly going to chelate some of those minerals even after 12 hours.
For the second approach, NBMI is taken every day for several days, then stopped for
several days. In those days off, specially near the middle, heavy doses of minerals are taken
to replenish the stores in the body.
5. Should I take NBMI with food or away from it?
This is not really known. However, since NBMI will grab on to many minerals as it
encounters them, it is likely to grab nutrient minerals in the food, and leave the body short.
Probably best not to eat for a little while after taking NBMI.
6. Does it matter whether you take NBMI with these:
non-mineral supplements such as: betaine HCl, digestive enzymes
herbs such as: milk thistle
animal extracts such as: adrenal cortex, desiccated beef liver
probiotics, prebiotics and fermented foods such as: saccharomyces boulardii, bifidobacteria,
lactobacilli, acacia gum, PHGG, lactulose, sauerkraut, kombucha, kimchi
[Unknown at present]
I am struggling with even a few mg of NBMI.
Some people don't have the proper enzyme pathway to break down sulfite to sulfate.
Molybdenum is an essential part of this pathway.
You can probably work out if you are low by what you eat. Legumes, such as beans, lentils,
and peas, are the richest sources of molybdenum. Grain products and nuts are considered
good sources, while animal products, fruit, and many vegetables are generally low in
molybdenum. Because the molybdenum content of plants depends on the soil molybdenum
content and other environmental conditions, the molybdenum content of foods can vary
considerably.
If you may be low, supplementing molybdenum may help improve the function of the
pathway. Consensus is that somewhere between 100mcg - 1000mcg (1mg) per day may be
helpful in these cases for adults.
Detailed discussion in this thread:
People have used this brand, although you may want to start with a smaller size capsule:
https://iherb.com/pr/Thorne-Research-Molybdenum-Glycinate-60-Capsules/52664
People who have never had amalgams generally can increase doses a lot quicker and
struggle less than the people who did have amalgams but this is not always true as we are
all different and have different things going on.
If I am asked what medications or supplements I am taking, eg, in hospital, should I mention
NBMI?
Probably not. Firstly, the medicos will not know what it is and what it does, so will have no
idea what effects it might have. Secondly, they may be inclined to blame your problem on the
NBMI rather than continuing to investigate.
Ofc, you may want to mention it to your own doctor if they are receptive to you taking
unproven drugs.
How is NBMI/OSR different to Andy Cutler Chelation?
The term “half-life” is important when comparing Cutler chelators and NBMI. Technically,
half-life is the time it takes for there to be half of the original dose *in its original form* still
circulating in the body. So if the half life of something is 1 day and you take 300mg of it, after
1 day, only 150mg will be left active in your body. After another day, provided you do not take
any more, there will only be 75mg circulating. After another day, only 37.5mg, and so on.
This is important when considering the differences between Cutler chelators and NBMI.
The chelators used in ACC grab the mercury and hold on to it fairly weakly. Some of the
mercury will be excreted by the body while in this form. This is how the ACC chelators work
to eliminate mercury.
However, if it is not excreted while the mercury is still bound, there comes a time when the
chelation bond will break and the mercury will be released. It will settle wherever it falls. This
process is called redistribution, as the chelator may pick it up from somewhere, but will drop
it somewhere else. In particular, it may pick it up from somewhere unimportant like the
bones, and drop it somewhere important like the brain. This has been known to cause a
number of side-effects that make people ill for a while.
ACC manages this by trying to keep the level of the chelator in the blood constant, so that
when a mercury atom is dropped, there is something to pick it up again. The way to do this is
to take the chelator at regular intervals according to its half-life. (For ALA, the half-life is
about 3 hours, although there are some studies that suggest it is shorter than this.)
NBMI is different in that when it grabs a mercury atom, it hangs on to it forever and
inactivates it so it can do no more harm. The NBMI/mercury complex circulates in the body
until it is excreted whole.
The half-life of NBMI is 22 hours, so after 22 hours, half of the NBMI will have exited the
body, along with any mercury bound to it.
Now there have been reports here of people taking NBMI suffering similar symptoms to
redistribution of mercury as experienced by ACC users. As described above, this cannot
happen.
That is not to say that there is not something happening that we cannot explain yet.
Research is ongoing into possible explanations.
Note that if you continue to take NBMI daily, the amount in your bloodstream will continue to
rise for a while. Using the example above, on the second day, you will have 450mg. On the
third day, you will have 525mg. On the fourth day, you will have 562.5mg and so on. After a
few weeks, your blood level will be very close to twice the dose you take every day.
Does NBMI cross the blood brain barrier?
Yes.
What is Redistribution?
The definition of mercury redistribution commonly refers to mercury ions “dropped” by
chelators. This can occur using chelating herbs like cilantro and chorella and it may happen
while using chemical chelators such as those used in the Andy Cutler (ACC) protocol. A
chemical chelator is man-made and was/is designed to snag targeted metal ions through a
“lock and key” mechanism. Many of these chelators were created to address water
contamination or drastically acute exposures; they were never envisioned to be used by
living biological systems like humans or animals. Accordingly, there is very little peer
reviewed literature that addresses their use in treating chronic toxic metal exposure.
One of our members, Darla Schafer, explained redistribution in a comment. Her answer was
so complete the admins agreed the majority of her description should be included in the
FAQs as a reference.
When mercury gets into your body, your body protects you by clearing it out of your blood
and then deposits it into safer, deeper places like your tissues and organs…which may also
include your brain. Therefore, it’s not circulating and causing more immediate harm; rather it
may be causing long term harm. This is known as the “compartmentalizing” of heavy metals.
All heavy metals may do this, as seen with both mercury and lead deposition inside the bone
matrix.
When you start chelating, after the blood borne metals are captured, deeper, hidden stores
of mercury can start migrating towards the bloodstream. This physiological “osmotic” shifting
occurs when heavy metals from areas of higher concentrations migrate to areas of lower
concentration.
If you are using a weaker chelator, then some of the mercury can be dropped, allowing it to
redeposit somewhere else: this is “redistribution.” And depending on the health of the
individual, how much mercury is present, how strong their immune system is, along with
other health complications, redistribution may lead to significant discomfort frequently
alluded to as “herxing.”
Until OSR became available, most chelators, including our natural glutathione, could drop
the loosely bound mercury. In the ACC protocol, dosing is frequent, on the half life of the
chelator, so the dropped mercury could be picked up right away. It’s an imperfect process
requiring dosing every 3,4,6 or 8 hours depending on the chelator used. This also includes
sleep time. At some point, the “round” is stopped, to give the body a rest. Chelated mercury
could then be dropped, leading to re-distribution of those mercury ions. Until OSR, this was
the best approach for some people…who have had great success with the protocol. And it
has been disastrous for others…one major issue being the constant interruption of their
sleep.
The claim of OSR is that it permanently binds to mercury ions. The two sulfur arms hold the
mercury in a locked embrace. The geometry of the OSR-mercury molecule is ideal as is the
chemical attraction between the two. OSR can be taken once or twice daily (half-life of 16-22
hours) and far less frequently if a tolerance needs to be built. At the beginning, taking breaks
from OSR dosing is a good idea as the body needs to repair the areas where the deeper
mercury has been held. And going slowly is a good approach, not adding more to one’s
existing physical challenges.
An additional point is that OSR can be used with other chelators. This is an advanced
technique. The thinking is that the more specialized chelators such as DMPS or DMSA are
used with an established OSR blood level. These would work as a team where older
chelators would be administered for specific heavy metals while the OSR functions as the
safety net, capturing any “dropped” metal ions. While we do not advocate this approach,
mentioning this practice makes a more complete discussion on heavy metal redistribution.
How does a healthy gut work?
The body's main methods of eliminating toxins in general are through the bowel and the
bladder, although some can also be eliminated through the skin (sweating) and the lungs.
So to support elimination you need all these things to be working well. And not all of these
methods apply to all toxins.
For the bowel, food typically takes from one to fifteen days to pass from mouth to anus. For
people with chronic constipation, it may take much longer.
The liver extracts toxins from the blood and puts them into bile which is released into the
upper part of the small intestine when we eat. The bile aids in the digestion of the food and
continues in the food through to the large intestine, typically within an hour or so after eating.
Most of the nutrients are absorbed in the small intestine.
In the large intestine, the food is initially liquid, quite mushy, and stays that way through the
ascending colon. In the transverse colon, the body starts to extract the moisture from the
food to produce stool. By the time it reaches the descending colon, is it quite dry, and the
longer it stays there, the dryer and harder it gets. People with constipation can testify how
dry and hard it is, and part of the reason for the constipation can be that it is just too hard
and compacted to be able to be moved on.
Now all the moisture being extracted from the food residue contains minerals, nutrients and -
you guessed it - toxins. The longer the stool stays in the large intestine, the more of each of
these things is absorbed. This is where weak chelators can drop metals so they are
reabsorbed. (About 80% of bile is actually reabsorbed and provides the raw materials for
making more bile.)
So to minimise the amount reabsorbed, you need the stool to be out of you fairly quickly, ie,
within about three days. This happens automatically with a good healthy natural food diet
which promotes growth of healthy gut bacteria.
Conventional wisdom in the gut health community says that with a healthy gut, you should
be going several times a day with quite large sizes each time.
Now the theory with binders is that they absorb toxins in the food mixture and hang on to
them so they go out with the stool. If they truly cannot penetrate the gut wall, this may well
be what happens. However, if you have a permeable gut wall (leaky gut), all sorts of things
that are not supposed to get into the bloodstream do.
The unfortunate thing about binders is that they tend to cause constipation in a lot of people,
so the stool hangs around longer giving more time for toxins to be reabsorbed.
Moral: Gut health is essential for the body to be able to eliminate toxins.
See this thread for info about improving the microbiome and constipation:
Are there other conditions that may have similar symptoms to mercury poisoning?
It is likely that all of us have multiple problems that cause our symptoms, rather than there
being a single cause. Resolving the symptoms may require more than just dealing with
mercury.
Vitamin B12 deficiency has symptoms very similar to mercury poisoning, and will restrict
repair of damaged nerves even after mercury is removed. Due to modern lifestyles and food
options, most of us are deficient in B12. This thread discusses B12 deficiency and how to
address it. Hint: taking B12 tablets is not going to help.
Another cause of brain fog and other symptoms is an imbalanced microbiome, the mass of
bacteria that live in all our guts. This can be remedied by use of diet, specific prebiotics and
sometimes probiotics. This thread discusses the gut and provides many references.
Where can I get NBMI/OSR?
The product will eventually be available legally from a company called Emeramed where it
was undergoing human trials in 2019-2022.
In the meantime, there are two companies which can supply the substance as a powder.
See this document for details:
https://www.facebook.com/notes/irminix-nbmi-emeramide-osr/how-to-get-nbmiosr/24151785
98600766/
Note that it is quite expensive and the price varies. Sometimes people do group buys within
a country to reduce the cost.
WARNING: NBMI/OSR/BDTH2 is an industrial chemical that is used for many purposes
such as water purification. You will sometimes find it listed quite cheaply at industrial
chemical suppliers. HOWEVER, the level of purity is almost always far less than from the
suppliers recommended here, and there is no indication of what contaminants may be in it.
We DO NOT RECOMMEND BUYING from random sites on the web, unless you are
prepared to get it independently tested to verify purity. NBMI from the suppliers
recommended here has been tested to be typically 99.7% pure. Industrial chemicals are
typically 98% pure.
This is something you are going to put in your body so purity is very important.
How should I store it?
NBMI is a very stable compound, but it is believed to deteriorate slightly over a long period,
months to years. Even after this time, it will still be reasonably effective.
This deterioration can be minimised by careful handling. In general it is better if left in a
sealed bag in the freezer. If you are using it daily, put a small amount, maybe enough for a
week, in an airtight container in the fridge. Leave the rest in the bag in the freezer.
Even if it is left out of the fridge for some time, it will still be effective.
How do I work out how much I am taking?
Many people use a set of small spoons to simplify the daily process. It is easier to measure
out a spoonful than to get out scales and measure the required amount. These spoons by
Superdosing are very convenient for small quantities.
https://www.ebay.com/itm/SuperDosing-Static-Free-Micro-Scoop-Variety-Pack-6-Milligram-3
0-Mg-/332617721467
There are packs of 3 and packs of 15 (5 x 3 sizes). Generally, a black spoon will be 3-6mg.
However, in order to work out exactly how much is in a spoon, a set of jeweller's or milligram
scales can be useful. These small devices can measure quantities down to about 20mg
accurately, and smaller amounts with less accuracy. They can be sourced from Ebay or
Amazon. Make sure they measure small amounts and that they are accurate. Just because
it shows down to 1mg does not mean it is accurate to that amount. Also beware that many
cannot measure less than 20mg with any accuracy.
Search on eBay, Amazon or elsewhere for “milligram scales” or “jewellers scales”. Cost will
be about $20-$50.
Things to look for:
It must be able to measure to an accuracy of 1 milligram (0.001g). Some only measure to
centigrams (0.01g). Some will show three decimal digits, but still only measure centigrams.
Most scales have an upper and lower limit on what they will measure accurately. The upper
limit may be 1g, 5g, 10g or 20g. The lower limit may not be stated anywhere, so ask before
ordering. Often it is 20mg, which means that if you need to measure small quantities, like
1mg or 5mg, it will not be accurate. If you are measuring quantities above the lower limit, the
scales should be accurate.
To measure quantities like 1mg or 5mg directly, a lab-grade scale is needed. These may cost
around $1000. However, you can often make do with the cheaper scales mentioned above.
This is only possible because NBMI doses do not have to be exactly the same. Measure out
20 black spoonfuls into the scale. Divide the amount by 20 to find the average quantity in a
spoonful. Alternatively, put something like a small coin on the scale initially to bring the
measured quantity up to the accurate range. Record the weight, then add the NBMI.
Subtracting the coin’s weight from the coin+NBMI weight will tell you how much NBMI you
have.
HOW TO USE THIS GROUP EFFECTIVELY
Do the admins of the group know everything about NBMI/OSR?
Not at all. Sometimes they think they know very little :-) The knowledge in this group is in the
members and their experience. The best information can be obtained by reading this FAQ
and if it is not here, asking in the group. Please do not PM the admins for advice on health
issues.
Are there rules for what can happen in the group?
The group Guidelines describe what the purpose of the group is and what sort of topics can
be raised here. It also outlines the responsibilities of members, expected behaviour and how
to invite other people.
https://www.facebook.com/notes/irminix-nbmi-emeramide-osr/guidelines-for-irminixnbmiemer
amideosr-group/2446691228782836/
Admins may delete posts, turn off commenting or kick people if they do not comply with the
guidelines.
Note particularly that the purpose of the group is to discuss heavy metal chelation using
NBMI/OSR. Posts on other topics will be refused. If in doubt, ask an admin.
If I find a link that I think might be useful to others, can I post it in the group?
Yes, certainly. With lots of people all researching different areas, we can build up a useful
collection of references. There are a few things you can do to make it more useful.
1. When you post a link, it is helpful to include a brief description of what it is about so that
when people are searching for something, it will come up in the search results. You can
make up your own summary of the item, or sometimes people just copy and paste part of the
abstract.
2. Try to make sure the article is fact-based. Scientific papers are great, as are educational
sites that, for example, might explain how a part of the body works. Blog posts can also be
good, but be careful that they are fact-based. Make sure that they quote scientific references
to support what they say, and that they are not just selling some product.
I was in the Andy Cutler Chelation group on Facebook, but I have now been banned. Why is
that?
The ACC group is huge, with over 60,000 members. With that many people, discussions can
quickly get off-topic which means that information may be hard to find. The admins there try
hard to keep the group focused and can be fairly harsh on off-topic discussions. In particular,
mentions of other methods of chelation can lead to the poster being banned from the group.
Moral: If you want to stay in the ACC group (and it has some wonderful information), stick to
the rules and do not mention things like OSR/NBMI, even in PMs to other members. A
number of people have been kicked for doing that.
I have problems that are not related to NBMI/OSR. Can I ask them here?
No, there are many better sources of information and we want to focus on NBMI/OSR use
here because there are no other places to learn.
For more general discussion on mercury/metal toxicity, see our sister group Heavy Metal
Chelation:
https://www.facebook.com/groups/heavymetalchelation/
Mercury-toxic people get illnesses just the same as people without mercury problems. Not all
illnesses are due to mercury toxicity! In fact most aren’t.
* For general mercury issues and emotional support, try:
https://www.facebook.com/groups/mercurydetoxsupport/
* For information about the Andy Cutler chelation methods, except as they relate to
NBMI/OSR, and after reading the section on ACC in this FAQ, try:
https://www.facebook.com/groups/acfanatics/
* For oxalate information, try:
https://www.facebook.com/groups/TryingLowOxalates/learning_content/
* For gut health issues, try:
https://www.facebook.com/groups/TheGutClubStoolTestDiscussionGroup/
https://www.facebook.com/groups/SIBOdoctor/
* For general health issues, try searching Facebook or Google for the name or symptoms.

FAQ For NBMI-OSR-Irminix-Emeramide

Uploaded by

Document Information

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

FAQ For NBMI-OSR-Irminix-Emeramide

Uploaded by

Copyright:

Available Formats

FAQ for NBMI/OSR/Irminix/Emeramide group | Facebook

THERE ARE NO DEFINITIVE ANSWERS ABOUT ANYTHING TO DO WITH NBMI/OSR.

You might also like