Noninvasively
track brain and
tissue perfusion.
The INVOS™ System enables
placement of up to four sensors
for monitoring of cerebral and
somatic tissues most critical to
the management of your patient.
This allows you to track stability of
cerebral and peripheral circulations
and help ensure adequate perfusion in
specific vascular beds. The INVOS™
monitor gives you immediate and
continuous regional oxygen saturation
data to enhance the assessment and
management of perfusion problems.
Protecting infants and
neonates in your care.
• Only device to provide noninvasive, simultaneous
cerebral/somatic oximetry
• Reflects venous reserve; the surplus of O2 remaining
after tissues have taken what they need
• Detects site-specific changes in blood oxygenation
• Often provides earlier warning than traditional
measures such as MAP, SpO2, ABGs and lactates1-3
• Helps clinicians detect and correct oxygenation
issues such as those associated with:
- Low cardiac output4
- Shock5 and seizures6
- Renal failure7
- Neurologic damage8-9
• Transforms subjective, intangible factors into
concrete, actionable data
• Regional, not systemic
• Noninvasive, real-time and continuous
• Helps determine need for and effects
of interventions
References
1. Hoffman GM, et al. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2005, pp 12-21.
2. Tobias JD. J. Intensive Care Med. 2008;23:384-8.
3. Simsic JM. INVOS Cerebral Oximeter Clinical White Paper Series. 2005;412(1): 1-4.
4. Chakravarti SB, et al. J Cardiothorac Vasc Anesth. 2009;23(5):663-667.
nirs™* in the nicu
5. Kaufman J, et al. Pediatr Crit Care Med. 2008;9(1):62-68.
6. Arca Diaz G, et al. Eur J Paediatr Neurol. 2006;10(1):19-21.
7. Hoffman GM, et al. Anesthesiology. 2005;103:A1327.
8. Dent CL, et al. J Thorac Cardiovasc Surg. 2005;130(6):1523-1530.
9. Kussman BD, et al. Circulation. 2010 20;122(3):245-254.
10. FDA 510k #K082327.
Distal Detector 11. Janelle GM, et al. Anesthesiology. 2002;96:1263-65.
12. Gottlieb EA, et al. Paediatr Anaesth. 2006;16(7):787-89.
13. Blas M, et al. J Cardiothorac Vasc Anesth. 1999;13:244-45.
Proximal Detector 14. Tobias JD. J Intensive Care Med. 2008;23:384-8.
LED Emitter
COVIDIEN, COVIDIEN with logo, Covidien logo and positive results for life are U.S. and internationally
INVOS™ Cerebral/Somatic Oximeter
registered trademarks of Covidien AG. Other brands are trademarks of a Covidien company.
™* and ®* are trademarks of their respective owners. ©2010, 2011 Covidien. All rights reserved.
Reflects Site-Specific Tissue Perfusion Noninvasively
Two depths of light penetration are used to subtract 11-PM-0258 MN21410
out data from the skin and skull, resulting in a brain
oxygenation value. The same concept holds for somatic
rSO2 values which capture the oxygenation of deeper tissue 6135 Gunbarrel Avenue
beneath the sensor. Boulder, CO
80301
www.covidien.com
800-635-5267 www.somanetics.com
A Helping Hand in
Early Detection
The INVOS™ Cerebral/Somatic Oximeter
helps detect ischemic threats to the brain
and vital organs by measuring blood
oxygen levels directly beneath its sensors.
It generates a vital sign called regional
hemoglobin oxygen saturation (rSO2),
which is a venous-weighted measure of the
hemoglobin bound oxygen remaining after
tissues have taken what they need. Decreases
in this venous reserve indicate increased
ischemic risk and compromised tissue
perfusion so the care team can intervene to
prevent or lessen ischemic complications
and injury.
The INVOS™ System is indicated for patients
of any weight, including infants and neonates.
While most traditional vital signs, lab draws
and subjective assessments reflect whole-body
status or may be time delayed, rSO2 is site-
specific, real-time and continuous.
In neonates, infants and children, cerebral and somatic rSO2 provide noninvasive indications
of oxygen changes in the cerebral and peripheral circulatory systems and may provide an early
indication of oxygen deficits associated with impending shock states and anaerobiosis.10
Its OxyAlert™* NIRSensors are expressly
tailored for infants and neonates. These
patient-friendly, noninvasive sensors apply
to the skin’s surface like a BandAid®*. Up to
four sensors may be placed (such as over the
brain, abdomen and renal area), providing
visibility to perfusion distribution across
the brain and body. Care teams today are INVOS™ data and standard
using this ability to help detect and manage markers of perfusion
ischemia related to conditions such as
feeding intolerance/NEC, sepsis, shock, Monitoring site-specific perfusion
congenital heart disease, intraventricular often provides an earlier warning of
hemorrhage, periventricular leukomalacia developing pathology and deteriorating
patient condition than systemic
and respiratory distress.
measures or laboratory tests which can
OxyAlert™* NIRSensors, together with the remain normal even when ischemia is
occurring at the regional level.11-14
INVOS™ System’s near-infrared light (NIRS)
technology, make monitoring of ischemic
threats to the brain and body safe and easy.
Markers of Perfusion
Immediate Minutes Hours
Hypotension/
Cardiac Arrest
Pulses Delayed CRT Lactate BP
rSO2 Color  Cold Extremities Metabolic Acidosis Oliguria Creatinine
Increased risk of irreversible cell/tissue damage
Courtesy of WIlliam I. Douglas, M.D.
A Helping Hand in
Early Detection
The INVOS™ Cerebral/Somatic Oximeter
helps detect ischemic threats to the brain
and vital organs by measuring blood
oxygen levels directly beneath its sensors.
It generates a vital sign called regional
hemoglobin oxygen saturation (rSO2),
which is a venous-weighted measure of the
hemoglobin bound oxygen remaining after
tissues have taken what they need. Decreases
in this venous reserve indicate increased
ischemic risk and compromised tissue
perfusion so the care team can intervene to
prevent or lessen ischemic complications
and injury.
The INVOS™ System is indicated for patients
of any weight, including infants and neonates.
While most traditional vital signs, lab draws
and subjective assessments reflect whole-body
status or may be time delayed, rSO2 is site-
specific, real-time and continuous.
In neonates, infants and children, cerebral and somatic rSO2 provide noninvasive indications
of oxygen changes in the cerebral and peripheral circulatory systems and may provide an early
indication of oxygen deficits associated with impending shock states and anaerobiosis.10
Its OxyAlert™* NIRSensors are expressly
tailored for infants and neonates. These
patient-friendly, noninvasive sensors apply
to the skin’s surface like a BandAid®*. Up to
four sensors may be placed (such as over the
brain, abdomen and renal area), providing
visibility to perfusion distribution across
the brain and body. Care teams today are INVOS™ data and standard
using this ability to help detect and manage markers of perfusion
ischemia related to conditions such as
feeding intolerance/NEC, sepsis, shock, Monitoring site-specific perfusion
congenital heart disease, intraventricular often provides an earlier warning of
hemorrhage, periventricular leukomalacia developing pathology and deteriorating
patient condition than systemic
and respiratory distress.
measures or laboratory tests which can
OxyAlert™* NIRSensors, together with the remain normal even when ischemia is
occurring at the regional level.11-14
INVOS™ System’s near-infrared light (NIRS)
technology, make monitoring of ischemic
threats to the brain and body safe and easy.
Markers of Perfusion
Immediate Minutes Hours
Hypotension/
Cardiac Arrest
Pulses Delayed CRT Lactate BP
rSO2 Color  Cold Extremities Metabolic Acidosis Oliguria Creatinine
Increased risk of irreversible cell/tissue damage
Courtesy of WIlliam I. Douglas, M.D.
Noninvasively
track brain and
tissue perfusion.
The INVOS™ System enables
placement of up to four sensors
for monitoring of cerebral and
somatic tissues most critical to
the management of your patient.
This allows you to track stability of
cerebral and peripheral circulations
and help ensure adequate perfusion in
specific vascular beds. The INVOS™
monitor gives you immediate and
continuous regional oxygen saturation
data to enhance the assessment and
management of perfusion problems.
Protecting infants and
neonates in your care.
• Only device to provide noninvasive, simultaneous
cerebral/somatic oximetry
• Reflects venous reserve; the surplus of O2 remaining
after tissues have taken what they need
• Detects site-specific changes in blood oxygenation
• Often provides earlier warning than traditional
measures such as MAP, SpO2, ABGs and lactates1-3
• Helps clinicians detect and correct oxygenation
issues such as those associated with:
- Low cardiac output4
- Shock5 and seizures6
- Renal failure7
- Neurologic damage8-9
• Transforms subjective, intangible factors into
concrete, actionable data
• Regional, not systemic
• Noninvasive, real-time and continuous
• Helps determine need for and effects
of interventions
References
1. Hoffman GM, et al. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2005, pp 12-21.
2. Tobias JD. J. Intensive Care Med. 2008;23:384-8.
3. Simsic JM. INVOS Cerebral Oximeter Clinical White Paper Series. 2005;412(1): 1-4.
4. Chakravarti SB, et al. J Cardiothorac Vasc Anesth. 2009;23(5):663-667.
nirs™* in the nicu
5. Kaufman J, et al. Pediatr Crit Care Med. 2008;9(1):62-68.
6. Arca Diaz G, et al. Eur J Paediatr Neurol. 2006;10(1):19-21.
7. Hoffman GM, et al. Anesthesiology. 2005;103:A1327.
8. Dent CL, et al. J Thorac Cardiovasc Surg. 2005;130(6):1523-1530.
9. Kussman BD, et al. Circulation. 2010 20;122(3):245-254.
10. FDA 510k #K082327.
Distal Detector 11. Janelle GM, et al. Anesthesiology. 2002;96:1263-65.
12. Gottlieb EA, et al. Paediatr Anaesth. 2006;16(7):787-89.
13. Blas M, et al. J Cardiothorac Vasc Anesth. 1999;13:244-45.
Proximal Detector 14. Tobias JD. J Intensive Care Med. 2008;23:384-8.
LED Emitter
COVIDIEN, COVIDIEN with logo, Covidien logo and positive results for life are U.S. and internationally
INVOS™ Cerebral/Somatic Oximeter
registered trademarks of Covidien AG. Other brands are trademarks of a Covidien company.
™* and ®* are trademarks of their respective owners. ©2010, 2011 Covidien. All rights reserved.
Reflects Site-Specific Tissue Perfusion Noninvasively
Two depths of light penetration are used to subtract 11-PM-0258 MN21410
out data from the skin and skull, resulting in a brain
oxygenation value. The same concept holds for somatic
rSO2 values which capture the oxygenation of deeper tissue 6135 Gunbarrel Avenue
beneath the sensor. Boulder, CO
80301
www.covidien.com
800-635-5267 www.somanetics.com
Noninvasively
track brain and
tissue perfusion.
The INVOS™ System enables
placement of up to four sensors
for monitoring of cerebral and
somatic tissues most critical to
the management of your patient.
This allows you to track stability of
cerebral and peripheral circulations
and help ensure adequate perfusion in
specific vascular beds. The INVOS™
monitor gives you immediate and
continuous regional oxygen saturation
data to enhance the assessment and
management of perfusion problems.
Protecting infants and
neonates in your care.
• Only device to provide noninvasive, simultaneous
cerebral/somatic oximetry
• Reflects venous reserve; the surplus of O2 remaining
after tissues have taken what they need
• Detects site-specific changes in blood oxygenation
• Often provides earlier warning than traditional
measures such as MAP, SpO2, ABGs and lactates1-3
• Helps clinicians detect and correct oxygenation
issues such as those associated with:
- Low cardiac output4
- Shock5 and seizures6
- Renal failure7
- Neurologic damage8-9
• Transforms subjective, intangible factors into
concrete, actionable data
• Regional, not systemic
• Noninvasive, real-time and continuous
• Helps determine need for and effects
of interventions
References
1. Hoffman GM, et al. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2005, pp 12-21.
2. Tobias JD. J. Intensive Care Med. 2008;23:384-8.
3. Simsic JM. INVOS Cerebral Oximeter Clinical White Paper Series. 2005;412(1): 1-4.
4. Chakravarti SB, et al. J Cardiothorac Vasc Anesth. 2009;23(5):663-667.
nirs™* in the nicu
5. Kaufman J, et al. Pediatr Crit Care Med. 2008;9(1):62-68.
6. Arca Diaz G, et al. Eur J Paediatr Neurol. 2006;10(1):19-21.
7. Hoffman GM, et al. Anesthesiology. 2005;103:A1327.
8. Dent CL, et al. J Thorac Cardiovasc Surg. 2005;130(6):1523-1530.
9. Kussman BD, et al. Circulation. 2010 20;122(3):245-254.
10. FDA 510k #K082327.
Distal Detector 11. Janelle GM, et al. Anesthesiology. 2002;96:1263-65.
12. Gottlieb EA, et al. Paediatr Anaesth. 2006;16(7):787-89.
13. Blas M, et al. J Cardiothorac Vasc Anesth. 1999;13:244-45.
Proximal Detector 14. Tobias JD. J Intensive Care Med. 2008;23:384-8.
LED Emitter
COVIDIEN, COVIDIEN with logo, Covidien logo and positive results for life are U.S. and internationally
INVOS™ Cerebral/Somatic Oximeter
registered trademarks of Covidien AG. Other brands are trademarks of a Covidien company.
™* and ®* are trademarks of their respective owners. ©2010, 2011 Covidien. All rights reserved.
Reflects Site-Specific Tissue Perfusion Noninvasively
Two depths of light penetration are used to subtract 11-PM-0258 MN21410
out data from the skin and skull, resulting in a brain
oxygenation value. The same concept holds for somatic
rSO2 values which capture the oxygenation of deeper tissue 6135 Gunbarrel Avenue
beneath the sensor. Boulder, CO
80301
www.covidien.com
800-635-5267 www.somanetics.com