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17:34:18.098 10/26/2022 Worker-0 [MuleRuntime].uber.

87: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5045bfe0-5526-11ed-94e0-06f2446467c7 ### skip sftp ###
17:34:33.610 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].hl7-order-map-flow.CPU_LITE @126add94 INFO
event:5aa081a0-5526-11ed-94e0-06f2446467c7 Received HL7 order from EMR partner :
MSH|^~\&|Epic|GHONCLAB|MuleSoft|GHONCLAB|20221026050432|INTF334379|ORM^O01|358|T|
2.5.1
PID|1||2000000118^^^EPI^MR||SITTHIRTEEN^ONCOLOGY^^^^^L||19880808|F|||7869 LAKER
RD^^LANSING^MI^48917^US^P^^EATON|EATON|(235)215-
2154^P^M^^^235^2152154~^NET^Internet^test@example.com|||||33941||||||||||||N
PV1||OP|^^^^^^^^GUARDANT ONCOLOGY LAB^^||||
1100199995^INPATIENT^ATTENDING^PHYSICIAN^^^^^NPI^^^^NPI||||||||||||33941
GT1||2827|SITTHIRTEEN^ONCOLOGY||7869 Laker Rd^^LANSING^MI^48917^US|||19880808|F|
1^Personal/Family|15^Self|198-49-8748
ORC|NW|1040264^EPC||33941|||^^^^^R^^||20221026050357|
INTF334379^INTERFACE^WORLDWISE^ORDERS IN^|||^^^^^^^^GUARDANT ONCOLOGY
LAB||||||||||||||||O
OBR|1|1040264^EPC|1000000872^Beaker|G360^GUARDANT360^GHEAP||20221026050357|||||
L|||||||||1.2.840.114350.1.13.0.1.7.2.798268_1161122||||Lab|||^^^^^R^^
NTE|1||Medical Consent: |OC
NTE|2||My signature constitutes a Certification of Medical Necessity, and I hereby
authorize and order Guardant Health, Inc. (GH) to perform Guardant360 testing and
curation for this patient as indicated on this requisition. If no test is selected,
this indicates an order for Guardant360 CDx. I have reviewed the medical consent on
the back of this form and will provide test interpretation to the patient as
appropriate. |OC
NTE|3||As may be required by applicable state laws and regulations, I have informed
the patient regarding somatic genomic testing, and the patient has consented for
the tests ordered. I understand that GH is relying on the diagnosis or diagnosis
code I have provided on the test requisition form in providing information about
potential therapeutic options and clinical trials associated with the reported
testing results, and that an incorrect diagnosis or diagnosis code would adversely
affect the relevance of the information provided by GH. I understand that I remain
free in my medical decisions on how to use the results of any Guardant Health
product(s) in my management of this patient. I have obtained the patient's written
consent to transmit the health data on this requisition form for the purpose of
processing this order and performing all ordered Guardant Health tests. I authorize
GH to request and obtain patient tissue samples when the tissue test is ordered and
follow-up with the patient to obtain a subsequent blood sample if a Guardant360
Response test is ordered. I understand that PD-L1 immunohistochemical testing is
performed using the 22C3 antibody according to manufacturer guidelines. I authorize
GH to select the most appropriate test (pursuant to the description in the GH
Annual Notice to Physicians: www.GuardantHealth.com/AnnualNotice). By submitting
this request you acknowledge and agree to our privacy policy
(www.GuardantHealth.com/contact/privacy-policy).|OC
NTE|4||I hereby authorize GH to release test results and relevant medical
information to the patient's insurance carrier for reimbursement purposes. I have
obtained the patient's consent for GH to submit and, if necessary, appeal claims on
the patient's behalf, as well as for GH to receive payment directly from the
patient's insurance carrier. I understand that Medicare will only pay for tests
that meet the Medicare coverage criteria and are reasonable and necessary to treat
or diagnose an individual patient. With respect to tests reimbursed by Medicare,
Medicaid or other third party payers, I attest that all ordered Guardant Health
tests are medically necessary and the results will be used in the management of the
patient's condition. I agree to provide a copy of relevant clinical history and
medical records in order to support a request from a health plan, at no cost to
Guardant Health. I acknowledge that patients who are United States residents may be
enrolled in Guardant Access, GH's Financial Assistance Program if eligibile and
only upon signing the assignment of benefits form.|OC
NTE|5||====Department Info====|OC
NTE|6||Department: EMH MED SURG [10101102]|OC
NTE|7||Location: EHS HOSPITAL [10101]|OC
NTE|8||Address Line 1: 123 Anywhere Street|OC
NTE|9||Address Line 2: Verona Wisconsin 53593-9179|OC
NTE|10||Phone: Dept: 555-555-5555|OC
NTE|11||Fax: Dept Fax: 555-555-5555|OC
NTE|12||====Department Info====|OC
NTE|13||====Visit Info====|OC
NTE|14||CSN: 45176|OC
NTE|15||====Visit Info====|OC
PRT|1|SP||OPO||||App Orchard Current
PRD^^urn:epic:apporchard.curprod^^^EPC^XX^^^urn:epic:apporchard.curprod
PRT|2|SP||Authorizing|1100199995^INPATIENT^ATTENDING^PHYSICIAN^^^^^NPI^^^^NPI||||
^^^^^^^^GUARDANT ONCOLOGY LAB^^|||||123 ANYWHERE STREET^^VERONA^WI^53593-
9179^US^^^DANE|(555)555-5555^^W^^^555^5555555~(555)555-5555^^FAX^^^555^5555555
DG1|1|I10|C40.01^Malignant neoplasm of scapula and long bones of right upper
limb^I10|Malignant neoplasm of scapula and long bones of right upper limb||^180;ORD
OBX|1|ST|3001010009^Advanced Cancer (Stage IIIB/IV-NSCLC, Stage III/IV-other cancer
types)^GHLQL||No||||||F|||20221026050429|||||||||||||||QST
OBX|2|ST|3001010010^Currently on Therapy? If yes, please list below.^GHLQL||
Targeted Therapy||||||F|||20221026050429|||||||||||||||QST
OBX|3|DT|3001010011^Date of Therapy Initation^GHLQL||20221022||||||F|||
20221026050429|||||||||||||||QST
OBX|4|ST|3001010014^The patient is seeking further treatment and is:^GHLQL||Newly
diagnosed (Stage III/IV)||||||F|||20221026050429|||||||||||||||QST
OBX|5|ST|3001010015^Has the patient received a Guardant360 or Guardant360 CDx
report since their most recent progression?^GHLQL||Yes||||||F|||
20221026050429|||||||||||||||QST
OBX|6|ST|3001010016^Is tissue-based comprehensive genomic profiling (CGP) from a
recent biopsy feasible?^GHLQL||Yes||||||F|||20221026050429|||||||||||||||QST
OBX|7|ST|3001010017^Has tissue-based CGP from a recent biopsy been performed with a
non-QNS result?^GHLQL||Yes||||||F|||20221026050429|||||||||||||||QST
OBX|8|ST|3001010018^Has tissue-based CGP from a recent biopsy already returned an
actionable result?^GHLQL||Yes||||||F|||20221026050429|||||||||||||||QST
SPM|1|^22G-299O0009&Beaker||Blood^Blood||||Blood, Venou^Blood, Venous||||||||||||Y
17:34:33.621 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.CPU_LITE @44f09436 INFO
event:5aa081a0-5526-11ed-94e0-06f2446467c7 Hl7 Order routed to epic flow - EMR
messageId : INTF334379
17:34:33.628 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present for component GT1-10: 'Guarantor Type' at segment 4 (GT1) of message
358
17:34:33.635 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present for component DG1-06: 'Diagnosis Type' at segment 24 (DG1) of
message 358
17:34:33.636 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present past end of segment (defined length 25) at segment 25 (OBX) of
message 358
17:34:33.636 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present past end of segment (defined length 25) at segment 26 (OBX) of
message 358
17:34:33.637 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present past end of segment (defined length 25) at segment 27 (OBX) of
message 358
17:34:33.638 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present past end of segment (defined length 25) at segment 28 (OBX) of
message 358
17:34:33.639 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present past end of segment (defined length 25) at segment 29 (OBX) of
message 358
17:34:33.640 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present past end of segment (defined length 25) at segment 30 (OBX) of
message 358
17:34:33.640 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present past end of segment (defined length 25) at segment 31 (OBX) of
message 358
17:34:33.641 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b WARN
event:5aa081a0-5526-11ed-94e0-06f2446467c7 recoverable message error: too many
values present past end of segment (defined length 25) at segment 32 (OBX) of
message 358
17:34:33.820 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.CPU_INTENSIVE @76759278 INFO
event:5aa081a0-5526-11ed-94e0-06f2446467c7 {
"Id": "ACK",
"Name": "ACK",
"MSH": {
"MSH-10": "358",
"MSH-11": {
"PT-01": "T"
},
"MSH-12": {
"VID-01": "2.5.1"
},
"MSH-03": {
"HD-01": "MuleSoft"
},
"MSH-04": {
"HD-01": "GHONCLAB"
},
"MSH-05": {
"HD-01": "Epic"
},
"MSH-06": {
"HD-01": "GHONCLAB"
},
"MSH-07": {
"TS-01": "20221026050432"
},
"MSH-08": "INTF334379",
"MSH-09": {
"MSG-03": "ACK",
"MSG-02": "O01",
"MSG-01": "ACK"
}
},
"Data": {
"ACK": {
"MSH": {
"MSH-10": "358",
"MSH-11": {
"PT-01": "T"
},
"MSH-12": {
"VID-01": "2.5.1"
},
"MSH-03": {
"HD-01": "MuleSoft"
},
"MSH-04": {
"HD-01": "GHONCLAB"
},
"MSH-05": {
"HD-01": "Epic"
},
"MSH-06": {
"HD-01": "GHONCLAB"
},
"MSH-07": {
"TS-01": "20221026050432"
},
"MSH-08": "INTF334379",
"MSH-09": {
"MSG-03": "ACK",
"MSG-02": "O01",
"MSG-01": "ACK"
}
},
"MSA": {
"MSA-02": "358",
"MSA-01": "AA"
}
}
}
}
17:34:33.826 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].hl7-epic-implementation-flow.BLOCKING @7d21f58b INFO
event:5aa081a0-5526-11ed-94e0-06f2446467c7 "MSH|^~\\'|MuleSoft|GHONCLAB|Epic|
GHONCLAB|20221026050432|INTF334379|ACK^O01^ACK|358|T|2.5.1\rMSA|AA|358\r"
17:34:37.490 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "START: Process Order",
"tracePoint" : "START",
"priority" : "INFO",
"elapsed" : 622,
"locationInfo" : {
"lineInFile" : "332",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "order-flow"
},
"timestamp" : "2022-10-26T12:04:37.488Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"deliveryCount" : 1
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.88: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:37.510 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "START: Invoking LIMS Order Endpoint",
"tracePoint" : "START",
"priority" : "INFO",
"elapsed" : 639,
"locationInfo" : {
"lineInFile" : "454",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "lims-order-subflow"
},
"timestamp" : "2022-10-26T12:04:37.505Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7"
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.88: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:37.521 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "START: Getting LIMS Connection Token",
"tracePoint" : "START",
"priority" : "INFO",
"elapsed" : 647,
"locationInfo" : {
"lineInFile" : "756",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "get-lims-token-subflow"
},
"timestamp" : "2022-10-26T12:04:37.513Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7"
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.88: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:37.823 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "INFO: Retrieved new LIMS Token",
"tracePoint" : "FLOW",
"priority" : "INFO",
"elapsed" : 954,
"locationInfo" : {
"lineInFile" : "787",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "get-lims-token-subflow"
},
"timestamp" : "2022-10-26T12:04:37.820Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"limsToken" : {
"code" : 201,
"message" : "Connection labvantage|@mulesoftwebservice06038467531478
created",
"connections" : {
"connectionid" : "labvantage|@mulesoftwebservice06038467531478"
},
"status" : "Created"
}
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.88: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:37.826 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "END: Getting LIMS Connection Token",
"tracePoint" : "END",
"priority" : "INFO",
"elapsed" : 958,
"locationInfo" : {
"lineInFile" : "822",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "get-lims-token-subflow"
},
"timestamp" : "2022-10-26T12:04:37.824Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7"
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.87: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:38.368 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "START: Delete LIMS Token",
"tracePoint" : "START",
"priority" : "INFO",
"elapsed" : 1500,
"locationInfo" : {
"lineInFile" : "832",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "delete-lims-token-subflow"
},
"timestamp" : "2022-10-26T12:04:38.366Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7"
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.88: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:38.439 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "INFO: Deleted LIMS Token",
"tracePoint" : "FLOW",
"priority" : "INFO",
"elapsed" : 1569,
"locationInfo" : {
"lineInFile" : "854",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "delete-lims-token-subflow"
},
"timestamp" : "2022-10-26T12:04:38.435Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"limsToken" : {
"code" : 200,
"message" : "Connection labvantage|@mulesoftwebservice06038467531478
cleared",
"status" : "OK"
}
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.87: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:38.442 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "END: Delete LIMS Token",
"tracePoint" : "END",
"priority" : "INFO",
"elapsed" : 1574,
"locationInfo" : {
"lineInFile" : "872",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "delete-lims-token-subflow"
},
"timestamp" : "2022-10-26T12:04:38.440Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7"
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.88: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:38.451 10/26/2022 Worker-0 [MuleRuntime].uber.88: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
"message" : "END: Invoking LIMS Order Endpoint",
"tracePoint" : "END",
"priority" : "INFO",
"elapsed" : 1582,
"locationInfo" : {
"lineInFile" : "535",
"component" : "json-logger:logger",
"fileName" : "process-order.xml",
"rootContainer" : "lims-order-subflow"
},
"timestamp" : "2022-10-26T12:04:38.448Z",
"content" : {
"message" : "5c9350f0-5526-11ed-94e0-06f2446467c7"
},
"applicationName" : "{project.artifactId}",
"applicationVersion" : "{project.version}",
"environment" : "val",
"threadName" : "[MuleRuntime].uber.88: [ent-epic-emr-gateway-exp-svc].order-
flow.BLOCKING @75e78e40"
}
17:34:38.454 10/26/2022 Worker-0 [MuleRuntime].uber.87: [ent-epic-emr-
gateway-exp-svc].order-flow.BLOCKING @75e78e40 INFO
event:5c9350f0-5526-11ed-94e0-06f2446467c7 {
"correlationId" : "5c9350f0-5526-11ed-94e0-06f2446467c7",
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