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MD SKIN
SOLUTIONS
LABORATORIES
AT A GLANCE
2nd Generation Family Business
12 13M
years Treatments
70
countries
4 Pluryal Mesoline Pluryal Mesoline 5
PRODUCT 3 ACTIONS
OVERVIEW 9 PRODUCTS
Pluryal Mesoline Skin - Body - Hair
Pluryal Mesoline are safe, highly concentrated and innovative Sterile Serums: Regenerate
Developed to allow aesthetic medical practitioners to improve the condition of the skin Pluryal Mesoline Refresh
(face and body) and hair. Pluryal Mesoline Hair
Featuring textures and compositions which are carefully developed to allow an optimal
penetration of the formulas into the skin or scalp.
Offering the widest range of ready-for-use formulations targeting all indications that
aesthetic practitioners face in their daily practice. Regulate
Pluryal Mesoline Shine
Pluryal Mesoline Antiox
Pluryal Mesoline Clear
Reshape
Pluryal Mesoline Tight
Pluryal Mesoline Facecontour
Pluryal Mesoline Bodyfirm
Pluryal Mesoline Bodycontour
6 Pluryal Mesoline Pluryal Mesoline 7
WHY
CHOOSE
PLURYAL
MESOLINE? GREEN SERUMS
Sterile serums with no added preservatives are used, in respect
with the “green beauty” philosophy. Vegetable components are
also present in many variants of the product to bring natural
benefits in the skin.
EFFICIENT SERUMS
The “Pluryal mesoline” sterile serums are manufactured in accordance with the Thousands of satisfied users and more than 10 million treatments
“GECISS SERUMS” technology. sold are the proofs of the products’ excellent results.
CONCENTRATED SERUMS
Main actives ingredients are highly concentrated, for a greater
efficacy and a better skin penetration during the treatment.
INNOVATIVE SERUMS
The R&D department focused on innovative associations of the
actives ingredients, in the most stable forms, in order to enhance
the performance of the products.
SHORT SERUMS
Each formula uses few ingredients for a greater efficacy of the
peculiar characteristics brought by each component.
SAFE SERUMS
The manufacturing process is in compliance with the highest safety
and compliance standards, operating in a certified full quality
system under ISO 22716 and GMP certifications.
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01 PRO-AGING
CARE
PLURYAL
elasticity and stretch-resistance properties.
Salmon DNA 10mg
Because of its restorative effects on proteins, Salmon DNA acts against collagen
MESOLINE destruction by sun rays, oxidative stress and tobacco (free radicals’ damages).
Vitamins (A, B5/B6/B3)
REFRESH
A careful selection of vitamins for their skin benefits:
Vitamin B5: strong hydrating effect
Vitamin A: anti-wrinkle effect
Vitamins B3 & B6: skin protective effect
Revitalising Action
Indications
The natural production of hyaluronic acid, collagen and elastin reduces with age and under Loss of glow and loss of elasticity in the sun exposed areas | As a preparation cure for
the influence of several external factors. As a result, wrinkles appear; the skin starts to the skin, before applying dermal fillers or botulinum toxin, to give more natural and
look tired due to a lack of tonicity and glow. harmonious results.
Hyaluronic acid used in a very high concentration, boosted by the regenerating action of
plant stem cells, salmon DNA and vitamins, can effectively combat these symptoms. Focus areas
Face | Neck | Décolletage | Dorsum of the hands
Advantages
Double hydration: the highest concentration of hyaluronic acid on the market (50mg)
combined to a high concentration of panthenol (vitamin B5)
Triple effect:
Hydrating
Plumping: the regeneration of collagen and elastic fibers thanks to the presence of plant
stem cells and salmon DNA.
Protective: presence of key vitamins
Clinically tested***
Composition
Panthenol
PLURYAL Excellent moisturizer, panthenol has been effectively used to treat sunburns, irritations,
dryness and other minor skin disorders. Helps diminishing wrinkles by infusing moisture
MESOLINE
into the deeper layers of the skin.
Ferulic acid
Ferulic acid acts like other antioxidants in that it helps to slow the aging process by
TIGHT reducing the effects of damaging free radicals on the skin. It is also thought to protect
against sun damage, as well as assisting in skin’s regeneration functions to tackle skin that
has already been over-exposed.
Lifting Action Minerals (copper, zinc, magnesium and manganese)
Skin regeneration, regulation and protection.
Indications
External aggravation, losses of structure and gravity help to create a lack of firmness in the
skin. The silicium-enriched DMAE and the protective action of the antioxidants Flaccid skin | Acne scars | Dilated pores | Stretch marks
enable the skin to be restructured and for the firmness of the skin to be improved.
Focus areas
Face contours | Décolletage | Stretch marks
Advantages
Collagen boosting effect thanks to the synergic action of Silicium, DMAE and minerals.
Protective effect preventing future damage thanks to the presence of a strong
antioxidant: Ferulic acid.
Clinically tested*.
Composition
Before After
DMAE
Several studies have proven that DMAE (dimethylaminoethanol) increases the dermal The treatment is carried out using Pluryal BOOSTER and Pluryal CLASSIC injections, then Pluryal
thickness of the skin leading to a lifting effect. mesoline TIGHT administered with a 1mm Pluryal mesoline Roller.
Courtesy of Dr. Vladlena AVERINA, Ukraine
Silicium
Silicium is important for optimal synthesis of collagen and for activating the hydroxylation *S. Boisnic, B. Slama published study on Pluryal Mesoline Refresh and Tight.
enzymes, playing a major role in the formation of collagen network, improving skin
strength and elasticity. It is also associated with the synthesis of glycosaminoglycans.
14 Pluryal Mesoline Pluryal Mesoline 15
Phytic acid
Currently, phytic acid is largely used as a depigmenting agent, acting through the
PLURYAL inhibition (by chelating copper and iron ions) of tyrosinase and also acting as an
antioxidant in bleaching hyperchromic spots.
MESOLINE
Pyruvic acid
Pyruvic acid has been used since years for the treatment of moderately photodamaged
skin or for skin lightening.
Focus areas
Face | Dorsum of the hands
Advantages
The only sterile serum product composed of Vitamin C+ 4 tyrosinase inhibitors.
Free from hydroquinone = compliant with EU regulations (hydroquinone is
prohibited in Europe).
Easy treatment, without social eviction.
Composition
Gingko Biloba
Anti-acne, anti-aging and antioxidant effects are clinically proven. Extracts from
PLURYAL
the seeds of the Ginkgo biloba tree have shown antibacterial activity on pathogens
that can cause skin infections such as acne by inhibiting the growth of Cutibacterium
acnes, Staphylococcus aureus and Streptococcus pyogenes.
CLEAR
clinical investigations which showed a significant improvement of acne lesions, by
minimal side effects.
Hyaluronic acid 10mg + Vitamin Complex (B5, B3, B8 & E)
Hyaluronic acid and panthenol maintain hydration, reducing the transfer of melanin,
Clarifying Action controlling the possibility of post inflammatory hyperpigmentation.
Niacinamide and tocopherol have an anti-inflammatory effect regulating the
redness caused by acne. In addition, the niacinamide regulates the amount of acne-
causing oil being produced by the glands in the skin.
Acne-prone skin also ages and requires a special treatment which can both control the
sebum secretion of the skin whilst maintaining its moisture level. The choice of
anti-inflammatories combined with a complex containing a high concentration of
Indications
hyaluronic acid as well as vitamins provides this double action.
Young adults with acne prone skin, blackheads, whiteheads and dilated pores.
Aging patients with acne prone skin presenting dilated pores, acne scars, pimples in the
T-zone area.
Focus areas
Face | Back
Advantages
The first and only care for treating aging acne-prone skin.
Regulates the sebum activity in the skin while preserving its hydration.
Composition
Mannitol 25mg
Protects the hyaluronic acid from being attacked by hydroxyl radicals (when an
MESOLINE
NAC stimulates glutathione biosynthesis, promotes detoxification, and acts directly as a
scavenger of free radicals.
Amino acids (taurine, proline, cysteine, cystine)
ANTIOX Amino acids help build dermal density, increase skin brightness, provide defenses from
environmental hazards and improve skin hydration. They contribute to collagen synthesis.
Zinc
Antioxidant Action Regulates the sebum secretion in the skin and stimulates the elastin synthesis.
Indications
Despite the presence of the cells’ antioxidant defense system to counteract the effects
of ROS (reactive oxygen species), oxidative damage accumulates over a lifespan and has
Dull skin (smokers, stressed patients, patients with imbalanced diet) | Young adult with
been implicated in aging as well as a number of age-related diseases. In addition, under
diet imbalances | Patients with aggressed skin: after skin trauma, surgery, sunburns, etc |
conditions which promote oxidative stress, e.g. inflammation or surgical procedures,
Highly recommended to perform a cure before dermal fillers injections to prolong and
endogenous antioxidants may not be sufficient to counteract the effects of ROS,
optimize the dermal fillers effects.
particularly as we age and endogenous antioxidative mechanisms and repair processes
become less effective.
Focus areas
Face (including dark circles) | Scalp
Advantages
A unique product to regulate the functions of “damaged” or aggressed skin or scalp.
Dual use: skin and scalp.
Protects against fast degradation of hyaluronic acid thanks to the presence of mannitol.
Composition
Before After
Glutathione 37.5mg & Alpha Lipoic acid
Before and after 2 treatment sessions with Pluryal Mesoline ANTIOX at 10-day intervals.
Powerful antioxidants, glutathione and alpha lipoic acid fight free radicals. They
increase the levels of Vitamins C & E in the body. Courtesy of Dr. Zara KHOUDAVERDYAN, Armenia.
Alpha Lipoic acid increases the level of glutathione in the body.
Glutathione has a clinically proven antiaging effect since it improves the
elasticity of the skin and reduces the wrinkles. It has in addition a whitening
effect described in various studies.
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02 HAIR
CARE
mixture extracted from pea (vegetal origin) to activate stem cells in the hair follicle,
promoting hair growth by its stimulatory effects on follicle stem cell growth, migration and
PLURYAL differentiation.
Vitamin B complex + Amino acids + Hyaluronic acid
MESOLINE Vitamins, amino acids and hyaluronic acid have all a positive effect on the hair.
Vitamin B6 (pyridoxine), Vitamin B5 (panthenol) and Vitamin B3 (niacin) promote healthy
HAIR
hair and hair growth.
Arginine and lysine (amino acids) have a positive effect on hair growth since hair is
composed of protein made up of linear amino acid chains.
Hyaluronic acid intensively moisturizes hair follicles, stimulates fibroblasts, and acts as
Hair Repair Action protection from antioxidants.
Caffeine
Caffeine promotes blood circulation of the scalp. As a result, hair becomes thicker and its
growth is stimulated.
Pluryal mesoline Hair features ingredients which are able to stop hair loss, promote hair
growth and improve the hair quality. Indications
This product is the best-seller of the range and number one treatment for haircare in
many countries.
Androgenic alopecia in men and women | Hair thinning | Telogen effluvium
(in association with Pluryal mesoline Antiox) | Post hair transplantation to activate
faster growth.
Focus areas
Scalp
Advantages
Triple effect:
Stops hair loss, stimulates hair growth and improves hair quality.
Provides an alternative to drugs prescribed for treating androgenic alopecia which often
have side effects or should be used continuously.
Fast results (after 6 / 8 sessions)
Composition
03 REMODELLING
CARE
Pluryal has
Genetics, bad eating habits and
developed 3
aging can have consequences on the
shape and the skin of the submental products which
and body areas. answer in a
targeted manner
Unwanted fat can be located in the these changes
submental area (the so-called double chin) and restore
or in some “body” areas such as thighs,
buttocks, abdomen, flanks, knees and even the patients’
inner arms. These localized fat deposits are confidence in their
often resistant to diet and exercise.
look.
Orange peel effect (cellulite) affects
the women more than men due to the
different fat, muscle, and connective tissue Facecontour | Bodycontour | Bodyfirm
distribution. It’s thought to affect 80 to 90
Every product taken alone
percent of women in varying degrees.
or used in combination
with others will give a
Body Skin slackening, often associated
with cellulite, can also occur after targeted action to remodel
pregnancy, after weight loss or simply with the targeted area.
aging.
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FLAVONOIDS
Aesculus Hippocastanum
PLURYAL Seeds from horse chestnut trees known for their action in reducing inflammation
and swelling.
FACECONTOUR
strengthen and regenerate skin tissue. Thanks to its high levels of silica, it is used to
heal wounds.
Ginkgo Biloba
It is rich in flavonoids and is a potent antioxidant that protects skin from the harmful
Shaping Action effects of free radicals that accelerate aging.
Indications
Submental fat represents an aesthetic problem in both younger and older male and
female patients. It can occur regardless of body mass. It is a major aesthetic concern Submental fat
because it is noticeable. Until recently, the treatment of submental fat has been limited
to invasive procedures which are associated with the risks of anesthesia, bleeding, Focus areas
bruising and scarring. Deoxycholic acid offers an innovative, clinically proven efficient
and easy solution for treating the submental fat.
Double chin
Advantages
Proven efficient in fat melting (hundreds of publications available on deoxycholic acid)
Presence of three flavonoids to neutralize the swelling reaction associated with
deoxycholic acid administration.
Before After
Composition
Before and after 3 sessions of Pluryal Mesoline FACECONTOUR in the lower third of the face, at
2-week intervals.
DEOXYCHOLIC ACID 1% Courtesy of Dr. Serine El ALI, Jordan
It is a bile acid which emulsifies and solubilizes dietary fats in the intestine. It
disrupts cell membranes in adipocytes and destroys fat cells in that tissue.
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PLURYAL
MESOLINE
BODYCONTOUR Deoxycholic acid
It is a bile acid which emulsifies and solubilizes dietary fats in the intestine. It disrupts cell
Shaping Action membranes in adipocytes and destroys fat cells in that tissue.
Indications
Aging, weight-gain or a hormonal disorder are the main factors responsible for Localized fat in the body area
the presence of fat in certain parts of the body (saddlebags on outer thighs, knees,
abdomen). A formulation composed of phosphatidylcholine and deoxycholic acid has Focus areas
been clinically proven to effectively treat these localized fat deposits. It is a highly
interesting alternative to invasive treatments such as liposuction especially for small fat Abdomen | Thighs | Buttocks | Hips | Knees
deposits.
Advantages
Clinically proven formulation efficient in fat melting.
Hundreds of publications confirmed the efficacy of the association of
phosphatidylcholine and deoxycholic acid in reducing the localized fat deposits.
Contains two main ingredients which have been extensively researched and
successfully used for fat emulsion.
Composition
PLURYAL
MESOLINE L-carnitine
Helps transport fat into the mitochondria of cells. Once there, they can be to generate
BODYFIRM
oxidized adenosine triphosphate, or ATP.
Centella asiatica
Normalizes the metabolism occurring in the cells of the connective tissue, shows anti-
inflammatory and draining activity and regulates microcirculation.
Smoothing Action Silicium
Stimulates the collagen synthesis and hence improves the skin’s firmness.
Ruscus aculeatus
It is a potent venous vasoconstrictor. It has flavonoids that enhance capillary resistance
Treating cellulite or “orange peel” requires a comprehensive approach to tackling and decrease vascular permeability and edema, which leads to an improvement in
its causes: swelling of the fat cells, a lack of firmness and venous insufficiency and lymphatic drainage.
circulatory failure. Pluryal Mesoline Bodyfirm features ingredients which have lipolytic,
draining and firming actions, to smooth out evenly the skin.
Indications
Cellulite (orange peel effect) | Skin slackening in the arms, legs and buttocks | Heavy legs
Focus areas
Legs | Thighs | Buttocks | Inner arms
Advantages
A strong formula dealing with the causes of orange peel effect globally.
Easy treatment with fast results.
Triple effect: tightening, draining and smoothing.
Composition
Caffeine
Caffeine is used for treating cellulite as it is involved in lipogenesis, lipolysis and Before After
the transport of glucose. LipoProtein Lipase which synthetize triglycerides is
inhibited by caffeine. Before and after 3 treatment sessions with Pluryal mesoline BODYFIRM at 1-week intervals.
Courtesy of Dr. Marina LEKOMTSEVA, Russia
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MESOLINE
COMBOS
HOW TO COMBINE
THE PRODUCTS?
Bodycontour +
Bodyfirm
Facecontour + Tight Localized fat and
Lower third of the face (submental fat): slackened skin /
Dissolve the fat orange peel
Tighten the skin Dissolve the fat
Smooth and tighten
Refresh + Shine the skin
Menopause patients
Antiox + Hair
Regenerate the skin
Telogen effluvium
Treat the pigmentary disorders
Neutralize free
radicals
Tight + Clear
Stimulate the hair
Oily skin with dilated pores or acne scars
growth
Regenerate the collagen and reduce
acne scars / dilated pores.
Refresh + Antiox
Regulate the excessive sebum secretion Dull skin of smokers
Regenerate the skin
Neutralize free
radicals
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PRODUCT REFRESH TIGHT SHINE CLEAR ANTIOX HAIR FACECONTOUR BODYCONTOUR BODYFIRM
ACTION REVITALIZING LIFTING BRIGHTENING CLARIFYING ANTIOXIDANT HAIR REPAIR SHAPING SHAPING SMOOTHING
Composition Hyaluronic acid DMAE Vitamin C Vitamin A Glutathione Copper peptide Deoxycholic acid 1% Phosphatidylcholine L-carnitine
50mg Silicium Kojic acid Ginkgo biloba Mannitol Plant stem cells Flavonoids: Deoxycholic acid Caffeine
Plant stem cells Panthenol Phytic acid Salicylic acid N-acetyl-cysteine Caffeine Aesculus Centella asiatica
Hippocastanum
Salmon DNA Ferulic acid Pyruvic acid Hyaluronic Alpha Lipoic acid Hyaluronic acid Equisetum Artichoke
acid 10mg arvense
Vitamins Minerals Morus alba extracts 4 Amino acids Amino acids Ruscus aculeatus
B vitamins Ginkgo biloba
Zinc B vitamins
Focus areas Face Face contours Face Face Face Scalp Double chin Abdomen Legs
Neck Décolletage Dorsum of the Back Dark circles Thighs Thighs
hands
Décolletage Stretch marks Scalp Buttocks Buttocks
Hands Hips Inner arms
Knees
Indications Loss of glow and Flaccid skin Melasma Acne prone skin in Dull skin Androgenic Submental fat Localized fat in Cellulite
loss of elasticity in young and aging alopecia in men the body (orange peel effect)
Acne scars Sun spots Aggressed skin
the sun exposed patients: and women
(trauma, surgery, Skin slackening in
areas Dilated pores Post-inflammatory
Blackheads sunburns) Hair Thinning the arms, legs and
hyperpigmentation
To prepare the skin Stretch marks To correct diet Telogen effluvium
buttocks
to aesthetic Whiteheads
imbalances Heavy legs
medical procedures Dilated pores Post hair
To prepare the transplantation to
skin to aesthetic activate faster
medical procedures growth
Content 5 x 5ml 5 x 5ml 5 x 5ml 5 x 5ml 5 x 5ml 5 x 5ml 5 x 5ml 10 x 5ml 10 x 5ml
PM_BRO_PRO_EN_RevD