SwissTa

Target Common name

Integrin alpha-4/beta-1 ITGB1 ITGA4
Aldose reductase AKR1B1
Carbonic anhydrase II CA2
Carbonic anhydrase I CA1
Mu opioid receptor (by homology) OPRM1
AMP deaminase 3 AMPD3
Tyrosinase TYR
Hydroxycarboxylic acid receptor 2 HCAR2
Bone morphogenetic protein 1 BMP1
Lysine-specific demethylase 4C KDM4C
Leukocyte adhesion molecule-1 SELL
Selectin E SELE
P-selectin SELP
Delta opioid receptor (by homology) OPRD1
Casein kinase II alpha CSNK2A1
G protein-coupled receptor 44 PTGDR2
Hepatocyte growth factor receptor MET
Purine nucleoside phosphorylase (by homology) PNP
Serine/threonine-protein kinase WEE1 WEE1
Lysosomal protective protein CTSA
Fatty acid binding protein adipocyte FABP4
Phosphodiesterase 5A PDE5A
c-Jun N-terminal kinase 1 MAPK8
Solute carrier family 22 member 12 SLC22A12
Dihydrofolate reductase DHFR
Tyrosine-protein kinase FYN FYN
Transthyretin TTR
Low molecular weight phosphotyrosine protein phosphatase ACP1
Lysine-specific demethylase 3A KDM3A
Thyroid hormone receptor alpha THRA
Thyroid hormone receptor beta-1 THRB
Aldehyde dehydrogenase ALDH2
Sodium channel protein type X alpha subunit (by homology) SCN10A
PI3-kinase p110-alpha subunit PIK3CA
Leukotriene A4 hydrolase LTA4H
Thymidylate synthase (by homology) TYMS
Tyrosyl-tRNA synthetase YARS
MAP kinase signal-integrating kinase 2 MKNK2
AMP deaminase 2 AMPD2
Neprilysin MME
Serotonin 2b (5-HT2b) receptor HTR2B
ADAMTS4 ADAMTS4
Tubulin--tyrosine ligase TTL
CREB-binding protein/p53 CREBBP
Integrin alpha-4/beta-7 ITGB7 ITGA4
Liver glycogen phosphorylase PYGL
AMP deaminase 1 AMPD1
Poly [ADP-ribose] polymerase-1 PARP1
P2X purinoceptor 3 P2RX3
Carbonic anhydrase XIV CA14
Carbonic anhydrase IV CA4
Carbonic anhydrase XIII (by homology) CA13
Carbonic anhydrase VA CA5A
Lysine-specific demethylase 4A KDM4A
Angiotensin-converting enzyme (by homology) ACE
Protein-arginine deiminase type-1 PADI1
Protein-arginine deiminase type-2 PADI2
Protein-arginine deiminase type-3 PADI3
ATP-citrate synthase ACLY
Egl nine homolog 1 EGLN1
Protein-arginine deiminase type-4 PADI4
Transitional endoplasmic reticulum ATPase VCP
GAR transformylase GART
Mitogen-activated protein kinase kinase kinase 14 MAP3K14
Serine/threonine-protein kinase PIM1 PIM1
Inosine-5'-monophosphate dehydrogenase 2 IMPDH2
Transketolase TKT
Phosphodiesterase 4B PDE4B
Phosphodiesterase 4D PDE4D
Epidermal growth factor receptor erbB1 EGFR
Cathepsin (H and K) CTSH
Beta amyloid A4 protein APP
Calpain 1 CAPN1
Aldo-keto reductase family 1 member B10 AKR1B10
Adenosine kinase ADK
Dihydroorotate dehydrogenase DHODH
Inosine-5'-monophosphate dehydrogenase 1 IMPDH1
Myeloperoxidase MPO
Serine/threonine-protein kinase Chk1 CHEK1
Estrogen receptor alpha ESR1
Cyclooxygenase-1 PTGS1
Estrogen receptor beta ESR2
Dual-specificity tyrosine-phosphorylation regulated kinase 2 DYRK2
Dual-specificity tyrosine-phosphorylation regulated kinase 1A DYRK1A
Serine/threonine-protein kinase PIM2 PIM2
Sodium/glucose cotransporter 1 SLC5A1
Integrin alpha-V/beta-3 ITGAV ITGB3
Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta- ITGAL ICAM1 ITGB2
Integrin alpha-V/beta-5 ITGB5 ITGAV
Integrin alpha-V/beta-1 ITGAV ITGB1
Matrix metalloproteinase 12 MMP12
Rho-associated protein kinase 1 ROCK1
Urokinase-type plasminogen activator PLAU
Caspase-6 CASP6
Matrix metalloproteinase 10 MMP10
DNA topoisomerase I TOP1
Prostanoid EP4 receptor (by homology) PTGER4
Prostanoid EP2 receptor (by homology) PTGER2
Nuclear factor NF-kappa-B p105 subunit NFKB1
Coagulation factor VII F7
 SwissTargetPrediction
Uniprot ID ChEMBL ID Target Class
P05556 P13612 CHEMBL1907599 Membrane receptor
P15121 CHEMBL1900 Enzyme
P00918 CHEMBL205 Lyase
P00915 CHEMBL261 Lyase
P35372 CHEMBL233 Family A G protein-coupled receptor
Q01432 CHEMBL2912 Enzyme
P14679 CHEMBL1973 Oxidoreductase
Q8TDS4 CHEMBL3785 Family A G protein-coupled receptor
P13497 CHEMBL3898 Protease
Q9H3R0 CHEMBL6175 Eraser
P14151 CHEMBL3161 Adhesion
P16581 CHEMBL3890 Adhesion
P16109 CHEMBL5378 Adhesion
P41143 CHEMBL236 Family A G protein-coupled receptor
P68400 CHEMBL3629 Kinase
Q9Y5Y4 CHEMBL5071 Family A G protein-coupled receptor
P08581 CHEMBL3717 Kinase
P00491 CHEMBL4338 Enzyme
P30291 CHEMBL5491 Kinase
P10619 CHEMBL6115 Protease
P15090 CHEMBL2083 Fatty acid binding protein family
O76074 CHEMBL1827 Phosphodiesterase
P45983 CHEMBL2276 Kinase
Q96S37 CHEMBL6120 Electrochemical transporter
P00374 CHEMBL202 Oxidoreductase
P06241 CHEMBL1841 Kinase
P02766 CHEMBL3194 Secreted protein
P24666 CHEMBL4903 Phosphatase
Q9Y4C1 CHEMBL1938209 Eraser
P10827 CHEMBL1860 Nuclear receptor
P10828 CHEMBL1947 Nuclear receptor
P05091 CHEMBL1935 Oxidoreductase
Q9Y5Y9 CHEMBL5451 Voltage-gated ion channel
P42336 CHEMBL4005 Enzyme
P09960 CHEMBL4618 Protease
P04818 CHEMBL1952 Transferase
P54577 CHEMBL3179 Enzyme
Q9HBH9 CHEMBL4204 Kinase
Q01433 CHEMBL2997 Enzyme
P08473 CHEMBL1944 Protease
P41595 CHEMBL1833 Family A G protein-coupled receptor
O75173 CHEMBL2318 Protease
Q8NG68 CHEMBL5549 Enzyme
Q92793 CHEMBL5747 Writer
P26010 P13612 CHEMBL2095184 Membrane receptor
P06737 CHEMBL2568 Enzyme
P23109 CHEMBL2869 Enzyme
P09874 CHEMBL3105 Enzyme
P56373 CHEMBL2998 Ligand-gated ion channel
Q9ULX7 CHEMBL3510 Lyase
P22748 CHEMBL3729 Lyase
Q8N1Q1 CHEMBL3912 Lyase
P35218 CHEMBL4789 Lyase
O75164 CHEMBL5896 Eraser
P12821 CHEMBL1808 Protease
Q9ULC6 CHEMBL1909486 Enzyme
Q9Y2J8 CHEMBL1909487 Enzyme
Q9ULW8 CHEMBL1909488 Enzyme
P53396 CHEMBL3720 Enzyme
Q9GZT9 CHEMBL5697 Oxidoreductase
Q9UM07 CHEMBL6111 Enzyme
P55072 CHEMBL1075145 Primary active transporter
P22102 CHEMBL3972 Ligase
Q99558 CHEMBL5888 Kinase
P11309 CHEMBL2147 Kinase
P12268 CHEMBL2002 Oxidoreductase
P29401 CHEMBL4983 Enzyme
Q07343 CHEMBL275 Phosphodiesterase
Q08499 CHEMBL288 Phosphodiesterase
P00533 CHEMBL203 Kinase
P09668 CHEMBL2225 Protease
P05067 CHEMBL2487 Membrane receptor
P07384 CHEMBL3891 Protease
O60218 CHEMBL5983 Enzyme
P55263 CHEMBL3589 Enzyme
Q02127 CHEMBL1966 Oxidoreductase
P20839 CHEMBL1822 Oxidoreductase
P05164 CHEMBL2439 Enzyme
O14757 CHEMBL4630 Kinase
P03372 CHEMBL206 Nuclear receptor
P23219 CHEMBL221 Oxidoreductase
Q92731 CHEMBL242 Nuclear receptor
Q92630 CHEMBL4376 Kinase
Q13627 CHEMBL2292 Kinase
Q9P1W9 CHEMBL4523 Kinase
P13866 CHEMBL4979 Electrochemical transporter
P06756 P05106 CHEMBL1907598 Membrane receptor
P20701 P05362 P05107 CHEMBL2096661 Membrane receptor
P18084 P06756 CHEMBL2096675 Membrane receptor
P06756 P05556 CHEMBL2111407 Membrane receptor
P39900 CHEMBL4393 Protease
Q13464 CHEMBL3231 Kinase
P00749 CHEMBL3286 Protease
P55212 CHEMBL3308 Protease
P09238 CHEMBL4270 Protease
P11387 CHEMBL1781 Isomerase
P35408 CHEMBL1836 Family A G protein-coupled receptor
P43116 CHEMBL1881 Family A G protein-coupled receptor
P19838 CHEMBL3251 Other cytosolic protein
P08709 CHEMBL3991 Protease
Probability* Known actives (3D/2D)
0.0972399887602 146 / 86
0.0972399887602 144 / 0
0.0972399887602 259 / 0
0.0972399887602 176 / 0
0.0972399887602 112 / 155
0.0972399887602 20 / 0
0.0972399887602 14 / 0
0.0972399887602 114 / 0
0.0972399887602 11 / 0
0.0972399887602 22 / 0
0.0972399887602 16 / 0
0.0972399887602 12 / 0
0.0972399887602 22 / 0
0.0972399887602 138 / 206
0.0972399887602 56 / 0
0.0972399887602 156 / 0
0.0972399887602 8 / 0
0.0972399887602 22 / 0
0.0972399887602 6 / 0
0.0972399887602 27 / 0
0.0972399887602 5 / 0
0.0972399887602 28 / 0
0.0972399887602 22 / 0
0.0972399887602 5 / 0
0.0972399887602 132 / 0
0.0972399887602 4 / 0
0.0972399887602 8 / 0
0.0972399887602 2 / 0
0.0972399887602 4 / 0
0.0972399887602 132 / 0
0.0972399887602 145 / 0
0.0972399887602 5 / 0
0.0972399887602 14 / 0
0.0972399887602 47 / 0
0.0972399887602 40 / 0
0.0972399887602 273 / 0
0.0972399887602 11 / 0
0.0972399887602 15 / 0
0.0972399887602 14 / 0
0.0972399887602 206 / 52
0.0972399887602 2 / 0
0.0972399887602 7 / 0
0.0972399887602 4 / 0
0.0972399887602 3 / 0
0.0972399887602 33 / 10
0.0972399887602 62 / 0
0.0972399887602 2 / 0
0.0972399887602 18 / 0
0.0972399887602 17 / 0
0.0972399887602 26 / 0
0.0972399887602 11 / 0
0.0972399887602 4 / 0
0.0972399887602 4 / 0
0.0972399887602 11 / 0
0.0972399887602 209 / 96
0.0972399887602 3 / 0
0.0972399887602 2 / 0
0.0972399887602 2 / 0
0.0972399887602 22 / 0
0.0972399887602 38 / 0
0.0972399887602 3 / 0
0.0972399887602 2 / 0
0.0972399887602 39 / 0
0.0972399887602 2 / 0
0.0972399887602 49 / 0
0.0972399887602 47 / 0
0.0972399887602 8 / 0
0.0972399887602 14 / 0
0.0972399887602 8 / 0
0.0972399887602 45 / 0
0.0972399887602 1 / 0
0.0972399887602 8 / 0
0.0972399887602 11 / 0
0.0972399887602 4 / 0
0.0972399887602 4 / 0
0.0972399887602 22 / 0
0.0972399887602 22 / 0
0.0972399887602 1 / 0
0.0972399887602 8 / 0
0.0972399887602 32 / 0
0.0972399887602 14 / 0
0.0972399887602 13 / 0
0.0972399887602 8 / 0
0.0972399887602 8 / 0
0.0972399887602 21 / 0
0.0972399887602 18 / 0
0.0972399887602 209 / 0
0.0972399887602 6 / 0
0.0972399887602 54 / 0
0.0972399887602 18 / 0
0.0972399887602 35 / 0
0.0972399887602 1 / 0
0.0972399887602 32 / 0
0.0972399887602 18 / 0
0.0972399887602 3 / 0
0.0972399887602 17 / 0
0.0972399887602 149 / 0
0.0972399887602 139 / 0
0.0972399887602 1 / 0
0.0972399887602 8 / 0