Peer ru Bela Mee) 1 aaa ae lee Bl nl eo Penn RR aot ae oa aoe Dee aun Pac ae ay suspicion of excessive mineralocorticoid secretion. See eee on a Paes See ae ata ROU eyCe ed Dee ese Lite eo De Re ae department complaining of chest discomfort, dizziness and Peer tO eet Rees medication for last 2 years but does not know the name of a A ee aa Re eer O/E- His blood pressure is 150/75 mm Hg with a pulse of coas ee Seer een ad + Cardiac marker: serum CK-MB, Troponin T= normal eee ee Ue eR aed Pa aedCe ed ry D 13) Se ees ns Cardiac Markers\ Cardiac Eneymes\ Marker of Myocardial damage 5 @ UProteins/enzymes which are released into blood and used to es ies Coe Cs ‘ Coram a i) Pee er ae cel + Released in cardiac injury. a ete acai) * ¥ Other conditions affecting cardiac muscle 7 (trauma, cardiac surgery, myocarditis etc.) ) an See ete eee om fone 7 Sy (kt 2d ad OE os OneCe ed B * Pementeen ars e @ aoe porn Per oat fa) eh ee aR) B een Pa re ori . essen ee ey S we eee ae oe oy ox DRC tacd Sena z * lk add notesCe ed ko 2d ee + Low mol. wt. heme. containing protein found in both skeletal ‘and cardiac muscle. De ae ee De oe Rae eee ee See ee ue ed Pe aes Oe Rese fs Pac aatyry rN CPK (CK) O 208. ATE : oe ere 2) [ Dimer which consist of 2 subunits: M (muscle) Pore Poe x ac) See ee es a re Seay & i ¥ CPKS- MM par ee SR ed after MI at about 4-8 hours, reaches a peak at approximately 24 hours, and returns 10 baseline after 48 to 72 hours. 6: rs pee lems Z2e@eea0€ OranCPK (CK) Cont, a an ery Sasa Paral} moe ee a Pesta eae Sas Pease ear a eee ee ee ae Re Dea LePee ee ea ads Re LR [oe Ce CER ea ad ¥ Cardiac specific troponin are net detected in normal healthy individuals. Ane gee hot eee irs ‘AMI and cTnT level may remain elevated for up to 10-14 days. Therefore, it is late marker of myocardial infarction Clidcto add notes Leer eee eae eg ‘amount of LDH-1. Patient with AMI have more LDH-1 than aed eee a BRB na ne myocardial infarction, peak in 2 days and return to normal in er d notesBiochemical Investigation in Hypertension- beers aeLier ee eS ee Pheer tplee (Gickto add notesDee RS eCuNLy Soe terete MNT allen Nasa mt Re tera essential hypertension, although they are important in: ee iad nce eek ul 7 + Complication of hypertension (eg- renal impairment). eee ee ene an at ee aa either for the specific cause or as part of overall en oeet eee eas ey Tt depend on intensity and duration of exercise.