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Application of Artificial intelligence on water testing

laboratory production processes

Ndala Yves Mulongo Jwalane Elizabeth Bosae


Faculty of Engineering and The Faculty of Enginnering and The
Built Enviroment Built Enviroment
University of Johannesburg University of Johannesburg
South Africa South Africa

Abstract— This study investigates the application of Artificial possible benefits to change the character of some duties in the
Intelligence in laboratory processes. The role of water testing industrial production processes. The advantages of integrating
laboratories is to perform water quality analysis to provide a level AI into production processes are numerous, and it can have a
of confidence to consumers that the product is safe to consume. big impact on those processes since it enables businesses to
Testing laboratory production processes can be complex and is
however time consuming, labour intensive, and prone to human
expand operations, increase efficiency, lower costs, and
errors. Thus, the implementation of AI systems in the laboratory improve quality. Predictive maintenance is made possible and
production processes may allow laboratories to be flexible in the downtime is decreased by AI's ability to automate repetitive
ever-changing demands of its customers. This study highlight the activities, monitor equipment performance, and spot anomalies
advantages and difficulties that laboratories encountered when in real time.
implementing the AI in the laboratory production processes. The
effectiveness and productivity of laboratory procedures are In addition, by predicting demand and adjusting inventory
likewise impacted by the installation of these AI systems. A levels accordingly, it helps improve supply chain operations.
PRISMA approach methodology was used to identify studies of Production processes can become more adaptable and sensitive
concern. The outcome of this study offer a platform for the
decision makers on opportunities and challenges of implementing
to shifting client demands thanks to AI. AI may assist
AI systems within laboratory processes to improve productivity businesses in identifying prospects for new products or
and customer satisfaction levels in testing laboratories. The services, optimizing pricing strategies, and enhancing the
present paper also contributes to the knowledge base over the customer experience by evaluating data from consumer
effect of Artificial Intelligence on productivity and customer interactions and market trends. This can assist businesses in
satisfaction in laboratory production processes. remaining competitive and better meeting the changing needs
of their clients.
Keywords—Artificial Intelligence, water testing, South Africa

I. INTRODUCTION The purpose of water quality analysis performed by testing


laboratories is to give customers some assurance that a product
Artificial Intelligence has emerged as one of the most is safe to use/consume. Customers of the laboratory anticipate
significant technologies of our tie, promising to transform every that information relevant to them and the findings of their
aspect of our lives. AI methods are used in various applications, samples will be managed in confidence. This is especially true
from health care to finance, transportation, and entertainment. now that South Africa has adopted the POPIA Act 2013, which
AI systems typically have elements of planning, learning, supports the protection of personal information processed by
control, logic, and perception. Machine learning, including both public and private organisations. This implies that
supervised and unsupervised learning, is one of the methods laboratories have a much bigger duty to implement IA systems
and tools that make up an AI system (UNESCO, 2020). that include the act. A study by Wirtz et al (2018) spoke on the
ability of AI in processing data and analysis many times over,
Advanced AI systems can benefit South Africa's current and how AI has served as a great improvement in managing
economic situation. AI systems might offer a way to mitigate public data.. It can be understood that the progressive
the problems brought on by load-shedding and Covid-19 implementation of AI in working environments can improve the
lockout incidents, as well as improve the unemployment rate production rates and thus the efficiency of laboratory
and corporate growth. Although some people in South Africa operations. Yahyaomi et al., 2023 discovered that an AI auto
are a little afraid of the introduction of AI since they believe verification system improved the efficiency of medical
that these systems would replace workers in certain areas. Yet, laboratories. A water testing laboratory based in Gauteng South
it does not particularly address the employment but rather Africa has been experiencing delays in the sampling activities
within their production workflow which leaves its customers waste. The results from the use of machine algorithm in a
frustrated. The productivity and efficiency levels of this kidney stone analysis offered a promising approach to
laboratory have also dropped significantly. Therefore, this improving the accuracy and efficiency of clinical laboratory
research study seeks to address the impact of AI in lab testing, while providing high quality results (Day, 2020). With
production processes mitigating challenges that affect the use of quality control in production processes, data fed to
sampling, sample analysis, reporting of results, authorization of the machines can be analysed and any abnormalities identified
results, and customer report generation. be corrected or removed. In another study, the use of
Laboratory Information Systems (LIMS) which contained
algorithms for quality control measures ensured that the
accuracy and reliability of laboratory results (Marescotti,
II. LITERATURE 2021).
Artificial intelligence is transforming the world in a
variety of ways, including production processes. In the past few • Production optimization
years, the application of AI has grown significantly in different
industries, including the laboratory sector. The literature review Production optimization through Artificial Intelligence could
will discuss AI and its impact on production processes. be employed to optimize production processes, identify
Artificial Intelligence integrates the capabilities that require inefficiencies, and improving output. The use of advanced
human intervention and can be performed by a machine. The computational tools and ML algorithms can analyse large
capabilities that AI computer systems possess, are those of amounts of data generated during bioprocessing and identify
problem solving, decision making, data analysis, human patterns and trends that can be used to optimize process
cognition, emotions and thinking (Nishant et al.,2020). performance (Fern ́andez-Lucas et al., 2021). In the
Machine Learning (ML) is the ability of a machine to act in a optimization of production processes, the integration of tasks
human intelligent manner without being explicitly programmed promotes productivity.
(Chopra & Khurana, 2018). Machine learning is then divided
into three divisions namely supervised, unsupervised, and
b. AI in laboratory production processes/ tools of AI in
reinforcement learning. It can be said that adopting AI and ML
production processes
in processes can enhance efficiency and productivity
(Ramachandran et al., 2021).
The application of AI in laboratory production processes has a
a. AI techniques Applications potential of transforming production processes. AI application
AI has numerous applications that can assist with the efficiency can improve efficiency, reduce costs, and produce better data
of processes in production. Through ML, Cognitive computing, quality (Hase et al., 2019; Wang et al., 2019). Its application
NLP and IOT, some common applications in production could be broken down into two categories namely automation
processes can be used in preventative maintenance, quality and decision-making.
control, and process optimization (Day, 2020; Li et al., (2020)
; Fern ́andez-Lucas et al., (2021)). It can be said that the use of • Automation
these applications leads to an improvement in customer
experience, increased efficiency, and cost savings in service Automation involves using machines to perform tasks that are
operations Wang et al., 2022. repetitive, time consuming or dangerous to humans. AI can
automate production processes by using robotics , machine
• Predictive maintenance/ Preventative maintenance vision, and ML e.g., Robots being used for repetitive tasks in a
laboratory for sample preparation, pipetting, and data entry.
As production processes become more automated, there is a O’Neill, 2021 argued that automating repetitive tasks may free
growing need to deal with predictive maintenance on those up the researchers to focus on more complex work. A study by
processes. Predictive maintenance AI tools can be used to (Jarvi et al., 2023) describes how drones were used to improve
monitor equipment performance and predict when the the process of measuring air pollution in a street canyon
maintenance is required. A study by (Li et al., 2020) showed network, as the readings were limited due to the size and shape
that with the use of AI predictive maintenance in a chemical of the street canyons and couldn’t accommodate mobile
plant there was a reduction of maintenance costs by 25% and laboratory used for the collection of air pollutants. Another
increased equipment efficiency by 20%. Through predictive study by (Pasquier et al., 2021) found that the use of aquatic
analysis benefits of proper planning, reducing downtime, and drones significantly reduced the time and effort required to
enhanced productivity can be achieved. collect samples from variety of surface water bodies, including
rivers, lakes, and ponds.
• Quality Control
• Decision making
Quality control AI can be used to in monitoring the product
quality in real time while identifying defects and reducing
AI can be used to support decision making in laboratory it is also important to note the challenges and limitations they
production processes. It can be used to analyse data whilst impose.
identifying patterns or variances which employees may miss.
AI can also be used to optimize production processes by
identifying the most efficient parameters for a given III. METHODOLOGY
experiment. Decision making applications improve the
AI systems typically have elements of planning,
efficiency and quality of processes. (Wang et al., 2019) showed
learning, control, logic, and perception. Machine learning
that the use of image analysis in histopathology led to higher
applications are based on ideas/data given to the machines so
accuracy and faster processing times compared to manual
that the machines may function on their own with little human
analysis. The use of human collaboration robots enhances the
interaction. Testing laboratory production processes could be
safety of humans by delegating hazardous and repetitive tasks
complex, and labour intensive.. Thus, the implementation of AI
to robots , allows for flexibility and adaptability to changes in
systems in the laboratory production processes allows
production demands (Hirata & Hirano, 2019).
laboratories to be flexible in the ever-changing demands of its
customers. This study seeks to address the impact of AI in lab
c. Benefits, challenges/limitations of AI in production production processes mitigating challenges that affect
processes sampling, sample analysis, reporting of results, authorization of
results, and customer report. A testing laboratory based in
Gauteng South Africa experiences delays in its daily activities
• Benefits within their production workflow which leaves its customers
frustrated. The productivity and efficiency levels of this
There are multiple benefits pertaining to the employment of laboratory have also dropped significantly. The main goal of
Artificial Intelligence in production processes as described in this paper is to review AI applications in laboratory setting and
the above sections. Research studies indicate that with AI how they impact the efficiency of laboratory operations,
implementation in production processes there will be increased performance of the laboratory and the customer satisfaction.
efficiency, reduced costs, improved quality. Thus, improving The outcome of this review will setting provide literature on the
the capabilities of organizations while achieving a competitive opportunities of and challenges of AI application in laboratory
advantage . AI systems can produce better quality data at setting. This review will also provide recommendations for
reduced costs (Hase et al., 2019). Through IOT there is better future research on AI in laboratory processes.
collaboration and data sharing (Denny-Gouldson, 2018).
PRISMA approach methodology was used to collect, analyse,
• AI challenges/limitations and interpret published literature on the impact of AI in
laboratory production processes. PRISMA methodology is
Although there are several benefits to the implementation of AI defined as a systematic methodology PRISMA methodology
in production processes, research has also argued on the used to review published information on a subject matter for
challenges and limitations of the use of the technology. With knowledge gaps, through scanning of the literature using
the use of AI to deal with big data there is also a concern over inclusion and exclusion criteria and making use of statistical
the privacy and security over intellectual property, confidential method for the interpretation of results (Selçuk, 2019). The use
information and generated data, the data needs to be protected of a twenty-seven checklist can be followed to formulate the
from unauthorized access and breaches (Hase et al., 2019; systematic review on AI impact in production processes. A
Denny-Gouldson, 2018; Wang et al., 2019). The use of AI in PRISMA methodology was then used to address the question
production processes the safety of human beings may be “What is the impact of AI on the Accuracy, efficiency of
compromised with the use of robots in shared workspaces laboratory processes”.
(Hirata & Hirano, 2019). The implementation costs of AI
technologies and systems can also be severe (O’Neill, 2021). A multiple search was conducted on studies relevant to the
Researchers argue that AI technologies may not fully replace topic. The search was performed in the following databases
human judgement(Mullin, 2018). Some industries may be namely, Web of Science, Science Direct, and the EBSCO host.
restricted in terms of regulations pertaining to cloud The following terms were applied to the search engine; (AI OR
infrastructure (Denny-Gouldson, 2018). AI systems are also as Artificial Intelligence) AND (Production processes OR
good as the data it has been trained on (O’Neill, 2021), therefore laboratory processes ) AND (operational efficiency OR
these systems may be susceptible to bias and raises a question Accuracy) . The different terms were used to produce a larger
of ethics. In smaller organizations it can become costly to search of published articles. The articles were refined with the
implement these Artificial Intelligence systems. AI based inclusion criteria of articles from 2013-2023, academic
inspection systems may require periodic updates to maintain its journals, peer reviewed articles. The exclusion criteria were
accuracy and effectiveness, which can become costly and time applied to articles that were not published in English,
consuming (Goffin, 2022). The application of AI technologies Documents which were not academic journals , were publisher
in production processes can revolutionize processes however, over the 10-year period. Due to the time constraint on the study
where data collection involved screening of the articles and
they were screened for specifics on laboratory setting, technologies to ensure the effective adoption of these
laboratory tests/analysis involving AI . technologies.

The article by Ayres et al., 2021 outlines the applications of AI


IV. FINDINGS in the analytical chemistry sector. The authors argue that AI has
the potential to process data, recognize patterns in the data,
The article by (Fantke et al.,2021) reviews the current AI data provide predicted results, and optimize processes in analytical
driven approaches, computational approaches, and process chemistry. ML algorithms can be applied to data, such as
modelling technologies in the chemical space which assist in chromatographic data, Mass Spectrometric data, Spectroscopic
the optimization of chemical processes. The author also data, and overall improve the efficiency of solving complex
discusses the how AI tools transition the world of chemistry R& problems. The limitations identified in the study is the
D through use of Machine learning, Natural language challenges regarding data quality, interpretability, and
processing, robotics which can contribute to waste reduction generalization. As the manner in which data is handled will
and reduced accidents in the workspace , processing of large affect the end result. Future research can look into the
data. The AI digital tools can assist in decision making, standardization and reproducibility of AI in analytical
increasing the efficiency of processes and increasing chemistry, also the need for developed algorithms.
performance. Limitations of employing these technologies in
the chemistry Research & Development is the need for skilled The study of Gruson et al., 2021 discusses the potential and
personnel to manage and interpret digital data, challenges with issues of utilising data science, AI and ML in the medicine
phasing in the digital tools into existing workflows or the laboratories but also discusses the importance of regulating the
system. Therefore, there is a gap in the standardization of employing AI. With the utilisation of the AI and ML
approaches in data collection, analysis, and interpretation. technologies there can be improvements in patient care,
improved diagnostics, data analysis, personalized medication.
The article by (Baccolo et al.,2021) discusses the use of an Challenges of fairness, biasness, data quality and interpretation
automated untargeted Gas Chromatography-Mass of AI models. The authors support that future research can
Spectrometry(GC-MS) in the analysis of a chemical sample. cover the protocols of implementing the AI technologies,
The authors discuss how samples are analysed by the GC-MS standardizing the format of the data, Validation of the
which contains AI algorithms that assist with the data analysis. implementation of the AI.
The study involved machine learning algorithms that were
trained to identify certain peaks. This type of AI technology can Bai et al., 2022 discuss the evolution of automation in
improve the accuracy and time it takes to perform the task. The laboratories. Laboratory automation evolved from
limitation identified in the study relates to the data entering, and implementation of hardware and software into the laboratory
the model interpretation. Thus, the Authors identifies a need for processes. These technologies saw the improvement in the
further research in areas of interpretability, generalization, productivity of laboratory processes. Then automation systems
transferability of the data. included data driven methods such as Machine Learning and
Artificial Intelligence, to optimize and improve the laboratory
The study by (Naugler & Church, 2019) discusses the current processes. Machine learning and Artificial Intelligence also
and potential automation and Artificial Intelligence (AI) improved the laboratory processes with the decision-making
technologies within the clinical laboratories. The author tasks. Knowledge graphs can also be used to identify the
indicates that with automation there are multiple benefits such relationship between substances and their properties.
as efficiency, improved accuracy of results, cost effectiveness Knowledge graphs enable data integration, and advanced
in laboratory processes. Processes such as sample preparation, analytics, improves data management and decision-making
testing of the samples, and the reporting of the produced results tasks. It can be noted that there are challenges with
may be enhanced with the use of AI technologies . AI also has standardization, the quality of data, and the implementation of
the potential to assist with the data analysis process by means knowledge graphs in laboratories.
of machine learning (ML) algorithms, predictive analysis, and
decision support systems. The limitations of the study were The article (Abolhasani & Kumacheva, 2023) provides a
over the concern over data security and privacy of information. perspective on the rise of self-driving laboratories in the
Challenges of integrating the AI systems into laboratory chemical and material science sector. Self-driving laboratories
processes. Thus, the Authors see a gap for future research in the utilize automation and Artificial intelligence to improve the
cost effectiveness of the AI and automation technologies, as process of discovery of chemical and materials. The author
well as the impact of AI and automation on the laboratory staff reports on the benefits of AI as increased process efficiency,
and the patients. Future research can also address the need for reproducibility of produced data. The limitations of this study
regulatory guidelines and ethical considerations with the were that self-driving laboratories are still relatively new;
application of AI and Automation. Future research needs to therefore, more research is needed to optimize their
look into the validation and standardization of implementing AI performance. The article suggest that future research look into
the cost and accessibility of the chemicals or materials. Another
factor that may be considered is the implementation of the self- make recommendations from its analysis of the laboratory
driving laboratories in different geographical regions. The bias processes and effectively optimize the operations, improving
of data selection and interpretation of the data are proposed for the efficiency of laboratory processes. There was no
future research. comparison done on the traditional method workflows to prove
that the AI system can be more efficient. The future research
Mateescu & Suba, 2013 discuss an AI Decision Supporting can address the algorithm bias in the AI workflow system,
Tool(DST) that assist laboratories in making informed investigate the data security and the data privacy of the AI
decisions about the testing procedures. The authors discuss the workflow system.
4 types of criteria to be considered when making informed
decisions with regards to selection of methods and allocation of A study by (Fedderson et al, 2023) involves an AI assisted
resources. The 4 types of criteria’s being related to technical digital metaphase chromosome workflow. A traditional
criteria, economic criteria, operational, environmental criteria. workflow requires manual labour and time consuming, thus in
The DST tool can assist laboratory management in scheduling event where there are staff shortages, the pressure in the
and improving processes of the laboratory. The right number of chromosome workflow becomes high. The study evaluated the
staff members, equipment needed and turnaround time effectiveness of using the Artificial Intelligence (AI) in a digital
calculation call all be done through the DST tool. The study analysis within a cytogenetics laboratory. A digital metaphase
proves that the DST tool can be regarded as a tool that can chromosome analysis workflow was used in conjunction with
ultimately improve the performance of the laboratory. The deep neural network (DNN) algorithms in the process of
limitation of this study is that the DST tool was conducted on a separating chromosomes and karyogram preparation. The
single case study, which makes the results of this study biased. implementation of DNN algorithms in the workflow showed
Future research can be conducted to test the DST in different improved efficiency and accuracy in the karyotype preparation
laboratories, to validate the effectiveness of the tool. process. Thus, freeing up the staff time to focus on other
responsibilities. Future studies may investigate the validation
Wang et al., 2019 discusses the use of AI technology to identify and optimization of the AI system in other areas.
drug designs by the analysis of large data sets. The benefits of
using AI in drug designs are that AI can reduce the cost of a The article by Keisuke et al., 2023 argue that laboratory
clinical trial, provide efficiency to the drug processes, processes such as , workflows, data handling and interpretation
determine the drugs toxicity. One of the studies the author has are fast being digitized. Traditional processes should either be
commented is where AI was successful in predicting the increased to keep up with the AI technologies or be replaced
toxicity of a compound in a drug, the compound aimed at altogether by AI technologies. The Authors also discuss the
targeting cancer. Also, AI in the study being deployed to benefits of implementing AI technologies in laboratory space
critically assess huge set of information to successfully identify such as it can assist with the making up for staff shortages and
new biomarkers for disease diagnosis and treatment. The AI process efficiencies. However, they also note that AI methods
algorithms are used can be trained to identify patterns in the bring various challenges in the laboratory space. Challenges
data making the diagnosis process efficient. The results of the over data privacy and security, biasness of the AI algorithms.
study are constrained because they were based on a literature The article also discusses the influence of AI adoption on
assessment of earlier studies, thus they are not presented as new technological, legal, societal factors, and clinical factors. It is
research findings. Use of AI in drug design applications is also apparent that AI may also remove the expertise of pathologists
relatively new and the data on the performance of it is limited. in areas they specialize in leading to burnout. The article
Future research may look into the biasness of the selection of reviews studies that evaluated the performance of the
data, the cost implications. Future research can also look into algorithms. Limitations noted in these studies is the small
the validation and calibration of the AI technologies. sample size and lack of the population diversity. Future
research should investigate more on the performance of
The article by Marescotti et al, 2022 discusses the how algorithms in larger populations, evaluate the AI algorithms
Artificial Intelligence (AI) was used to assist with the that can detect and remove biases in existing data.
optimization of laboratory workflow during the Covid-19
pandemic. Since laboratory processes make it challenging to The article by (Steiner et al., 2020) discusses the potential of
implement social distancing measures AI can be used in the Artificial Intelligence (AI) of improving the accuracy
laboratory processes. The implementation of AI workflow reproducibility and efficiency of the process of diagnoses in
system done, the system utilised machine learning algorithms pathology. The review discusses the widespread of AI
in analysing data form the different processes. The authors applications in pathology laboratories and the authors argue that
argue that with the implementation of the AI system the the AI applications still have a gap in the translation
laboratory was able to achieve quicker turnaround times which applications in the laboratory space. Recent applications of AI’s
ultimately correlates with customer satisfaction. The workflows ability to digitalize pathology images has seen significant
were optimized and resources used effectively. With the use of improvements in the laboratory workflow. Expert level
the system, it was able to identify bottlenecks within the performance has also been observed with the utilisation of ML
processes and they could be resolved. Th use of this system can tools within the different clinical laboratory disciplines. AI has
also benefitted this pace by increasing the productivity levels of studies’ PRISMA methodology to acquire data. The project’s
in the operation processes, ultimately assisting with the staff findings demonstrate the potential of AI to enhance laboratory
shortage . AI algorithms implemented in this space can assist procedures. The literature demonstrated several AI
with filtering of out negative biopsies and automating routine applications, such as automation, ML, knowledge graphs, and
tasks such as mitosis counting. With the use of the AI the review DST, which improved laboratory workflows’ productivity,
indicated that it is also important to note the potential biasness accuracy, and decision-making. The AI technologies and
in the quality of data. Future research can investigate the systems helped with process optimization, resource allocation,
standardization and regulation of the data and algorithms. and bottleneck detection, which increased efficiency and sped
up the turnaround times. Additionally, the research’ AI
The article by Derbenev et al., 2022 reviews software tools and algorithms demonstrated the capacity to large data, forecast
their use in research laboratories. The review is based on a outcomes, and support decision-making processes. The study
software designed to assist with the planning and performing of was conducted with the aim of addressing the difficulties
chemical experiments. Increase in digitalization opens up an testing laboratory face, and how such difficulties may affect lab
opportunity of using the computational tools to streamline operations. The study’s goal was to offer insights that help
routine work in laboratories. The authors further discuss the guide decision-making and aid in the deployment of AI
scope of the software tools. Reaction prediction tools use technologies to address problems, enhance productivity,
machine learning algorithms to predict chemical reactions. improve customer satisfaction. It was done by investigating
Optimization of reactions can also be achieved through how AI has affected laboratory production processes.
simulation of chemical processes. The study indicates that Recommendations can be made considering the finding. The
software tools improve the efficiency of chemical processes, validation and optimization of AI system algorithms in different
and that these tools also have their limitations which indicate laboratory environments to ensure they are effective across all
the lack in standardization and validation of the algorithms. different applications. Also, efforts should be made to address
Future research can address the validation and standardization challenges related to data standardization, algorithm bias ,
of the algorithms, bias and errors of the algorithms that can algorithm interpretability, and privacy and security in AI
promote green and sustainable chemistry. applications in laboratory processes. Future efforts should also
be made to include larger and diverse populations in AI
The study by (Grady et al., 2020) Technologies discussed in the applications to ensure that algorithms perform effectively.
review include optical sensors, biological sensors, Researchers and scientists should collaborate more to promote
electrochemical sensors ,remote sensing technologies. The knowledge sharing, best practices and the development of AI
benefit and limitations of each of the technologies is discussed driven solutions specific to the needs of laboratory production
by the authors. Optical sensors may be used to measure the processes.
absorbing and scattering of light particles found in the water,
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