AMYA POLYTECHNIC COLLEGE INC.

Tulip Drive, Corner Casiana Villa Abrille St, Davao City

College Department
BS PHARMACY

Clinical Pharmacy and Pharmacotherapeutics 2

Understanding Renal Disorders

ASSIGNMENT 2

_________________________________________________________________________________________
Name:___________________________________ Date:________

1. A 59-year-old mother with a history of hypertension and type 2 diabetes presents with
fatigue, pedal edema, and elevated serum creatinine levels.
Case Discussion:
a. Explore the stages of CKD (Chronic Kidney Disease (CKD)
b. Risk factors
c. Complications
d. Discuss the importance of:
I. Blood pressure control and the medications commonly used in this case.
And why?
II. Blood sugar control and its pharmacotherapy regimen. And why?
e. Review management strategies, including lifestyle modifications and
pharmacotherapy.

2. A male in his mid-forty admitted with sepsis develops oliguria, elevated serum urea and
creatinine levels, and fluid overload.
Case Discussion:
a. Examine the etiology and pathophysiology of AKI (Acute Kidney Injury) including
pre-renal, intrinsic, and post-renal causes.
b. Discuss the RIFLE (Risk, Injury, Failure, Loss, End-stage kidney disease) criteria
for AKI staging and management approaches, such as fluid resuscitation,
diuretics, and renal replacement therapy.

3. A 10-year-old girl presents with periorbital edema, proteinuria, hypoalbuminemia, and

hyperlipidemia.
Case Discussion:
a. Understand the underlying renal pathology in nephrotic syndrome, including minimal
change disease, membranous nephropathy, and focal segmental glomerulosclerosis.
b. Discuss diagnostic tests (e.g., urinalysis, renal biopsy) and treatment options, including
corticosteroids, immunosuppressive agents, and dietary management.