Quais são algumas das plantas medicinais do Cerrado brasileiro que foram estudadas por

suas propriedades antioxidantes e anticancerígenas?

Como esses antioxidantes naturais matam as células tumorais e protegem as células

saudáveis dos danos da quimioterapia?

Quais são algumas aplicações potenciais dessas plantas medicinais na terapia do câncer?

Resume: Several medicinal plants from the Brazilian Cerrado have been studied for
their antioxidant and anticancer properties. Some of these plants include: 1.
Stryphnodendron adstringens (barbatimão): Studied for its antiulcerogenic and
antifungal effects 1. 2. Campomanesia adamantium (Guavira): Investigated for its
antidiabetic properties, anti-inflammatory, and diuretic actions 1. 3. Senna velutina:
Studied for its antitumour activity in a leukaemia cell lineage 1. 4. Jacaranda and
Harconia genera: Other examples of medicinal plants from the Cerrado commonly
used in folk medicine 1. These plants have shown potential in exhibiting antioxidant
and anticancer properties, making them valuable candidates for further research
and potential therapeutic applications.

Several medicinal plants from the Brazilian Cerrado have been studied for their
antioxidant and anticancer properties. Some of these plants include: 1.
Stryphnodendron adstringens (barbatimão): Studied for its antiulcerogenic and
antifungal effects 1. 2. Campomanesia adamantium (Guavira): Investigated for its
antidiabetic properties, anti-inflammatory, and diuretic actions 1. 3. Senna velutina:
Studied for its antitumour activity in a leukaemia cell lineage 1. 4. Jacaranda and
Harconia genera: Other examples of medicinal plants from the Cerrado commonly
used in folk medicine 1. These plants have shown potential in exhibiting antioxidant
and anticancer properties, making them valuable candidates for further research
and potential therapeutic applications.

Resume: Natural antioxidants protect cells from damage induced by reactive

oxidative species (ROS) such as superoxide anion (O2•−) and hydrogen peroxide
(H2O2) 1. ROS are involved in various cellular processes, but if they are not properly
regulated by the antioxidant system, they may cause the oxidation of biomolecules,
leading to deleterious effects 2. Studies have shown that medicinal plants from the
Brazilian Cerrado have the potential to induce antioxidant response element (ARE)
activation in cells, which encodes protective proteins such as phase II detoxification
enzymes and antioxidant enzymes 10. These protective proteins can help kill
tumour cells and protect healthy cells from chemotherapy damage 1. Additionally,
some medicinal plants from the Cerrado have been found to have anti-
inflammatory and anti-tumour properties, which can also contribute to their ability
to kill tumour cells and protect healthy cells 1. Overall, the natural antioxidants
found in medicinal plants from the Brazilian Cerrado have the potential to regulate
ROS and protect cells from damage, making them valuable candidates for further
research in cancer therapy.
Natural antioxidants found in medicinal plants from the Brazilian Cerrado protect
cells from damage induced by reactive oxidative species (ROS) such as superoxide
anion (O2•−) and hydrogen peroxide (H2O2) 1. ROS are involved in various cellular
processes, but if not properly regulated by the antioxidant system, they may cause
the oxidation of biomolecules, leading to deleterious effects 10. Studies have shown
that medicinal plants from the Brazilian Cerrado have the potential to induce
antioxidant response element (ARE) activation in cells, which encodes protective
proteins such as phase II detoxification enzymes and antioxidant enzymes [T10].
These protective proteins can help kill tumour cells and protect healthy cells from
chemotherapy damage 1. Moreover, some medicinal plants from the Cerrado have
been found to have anti-inflammatory and anti-tumour properties, which can also
contribute to their ability to kill tumour cells and protect healthy cells 1. In summary,
the natural antioxidants found in medicinal plants from the Brazilian Cerrado have
the potential to regulate ROS and protect cells from damage, making them valuable
candidates for further research in cancer therapy.

Resume: The medicinal plants from the Brazilian Cerrado have several potential
applications in cancer therapy, including:
1. Antioxidant and Anticancer Activity: These plants have shown antioxidant and
anticancer properties, indicating their potential use as sources of effective
pharmacological compounds for cancer therapy 1.
2. Protection Against Chemotherapy Toxicity: The natural antioxidants found in
these plants have the potential to protect healthy cells from the damage caused by
chemotherapy, thereby improving the clinical response to chemotherapy and
reducing its toxic side effects 10, 7.
3. Development of New Drugs: The identification of effective pharmacological
compounds from these plants may facilitate the development of alternative
therapeutic strategies and the design and selection of new drugs for cancer therapy
1.
4. Future Therapeutic Approaches: Insights into the cell death profile induced by
extracts from Cerrado plants provide perspectives for future therapeutic approaches
in cancer treatment 1. In summary, the medicinal plants from the Brazilian Cerrado
hold promise for various applications in cancer therapy, ranging from their
antioxidant and anticancer activities to their potential in protecting against
chemotherapy toxicity and contributing to the development of new therapeutic
approaches.
The medicinal plants from the Brazilian Cerrado have several potential applications
in cancer therapy, including their antioxidant and anticancer properties, their
potential to protect healthy cells from chemotherapy toxicity, their contribution to
the development of new drugs for cancer therapy, and their prospects for future
therapeutic approaches in cancer treatment 1, [T7], [T10]. These plants have shown
promise in exhibiting antioxidant and anticancer properties, making them valuable
candidates for further research and potential therapeutic applications.