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    Group 1 was assigned to explain the basic principles by which changes in the subcellular localization of signaling proteins can be used as a mechanism to transmit information. Group 2 was asked how a protein localized mostly in the nucleus can respond to signaling changes in the cytosol or plasma membrane. Group 3's question was about the different mechanisms by which phosphorylation can regulate the nuclear–cytoplasmic localization of a protein. Group 4's question regarded how internalization of a membrane-bound receptor can affect signaling pathways involving that receptor. Group 5 was asked to explain what receptor desensitization means. Group 6 was assigned to discuss how a protein's signaling properties could differ depending on its subcellular localization.

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    Group 1 was assigned to explain the basic principles by which changes in the subcellular localization of signaling proteins can be used as a mechanism to transmit information. Group 2 was asked how a protein localized mostly in the nucleus can respond to signaling changes in the cytosol or plasma membrane. Group 3's question was about the different mechanisms by which phosphorylation can regulate the nuclear–cytoplasmic localization of a protein. Group 4's question regarded how internalization of a membrane-bound receptor can affect signaling pathways involving that receptor. Group 5 was asked to explain what receptor desensitization means. Group 6 was assigned to discuss how a protein's signaling properties could differ depending on its subcellular localization.

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    5 views1 page

    Tema5-SC Questions

    Uploaded by

    alex
    Group 1 was assigned to explain the basic principles by which changes in the subcellular localization of signaling proteins can be used as a mechanism to transmit information. Group 2 was asked how a protein localized mostly in the nucleus can respond to signaling changes in the cytosol or plasma membrane. Group 3's question was about the different mechanisms by which phosphorylation can regulate the nuclear–cytoplasmic localization of a protein. Group 4's question regarded how internalization of a membrane-bound receptor can affect signaling pathways involving that receptor. Group 5 was asked to explain what receptor desensitization means. Group 6 was assigned to discuss how a protein's signaling properties could differ depending on its subcellular localization.

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    © All Rights Reserved
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    Cada grup respon la pregunta assignada al seu grup

    Grup
    Explain the basic principles by which changes in the subcellular localization of signaling proteins can be used as a 1
    mechanism to transmit information
    In your studies of how a cell responds to stimulation by a specific extra-cellular growth factor, you discover that a 2
    downstream protein translocates from the nucleus to the cytoplasm upon stimulation. How is it possible for a
    protein localized mostly in the nucleus to respond to signaling changes in the cytosol or plasma membrane?
    What are the different mechanisms by which phosphorylation can regulate the nuclear–cytoplasmic localization of 3
    a protein?

    In what ways can internalization of a membrane-bound receptor affect signaling pathways involving that receptor, 4
    and the dynamics of the response?

    What does mean desensitization of a receptor? 5


    How could the signalling properties of a protein differ depending on its subcellular localization? 6

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