Title: The Challenges of Crafting a Thesis on Ventilator-Associated Pneumonia

Crafting a thesis on Ventilator-Associated Pneumonia (VAP) can be an intricate and challenging

task, requiring in-depth research, comprehensive analysis, and a nuanced understanding of medical
concepts. As one delves into the complexities of this critical healthcare issue, several difficulties
emerge, making the assistance of specialized services invaluable.

One of the primary challenges faced by individuals undertaking a thesis on VAP is the need for a
profound grasp of medical literature and research. Navigating through a plethora of scholarly
articles, clinical studies, and medical databases demands both time and expertise. Furthermore, the
evolving nature of medical knowledge necessitates staying abreast of the latest advancements in the
field, adding an additional layer of complexity.

The technical nature of the subject matter poses another obstacle. Understanding the intricate details
of ventilator-associated pneumonia, including its etiology, risk factors, preventive measures, and
treatment modalities, requires a high level of medical proficiency. Translating this knowledge into a
coherent and comprehensive thesis adds an extra layer of difficulty.

Moreover, the research process itself can be time-consuming, with the compilation and analysis of
vast amounts of data, statistics, and case studies. The synthesis of this information into a well-
structured and cohesive thesis demands not only dedication but also a keen eye for detail.

Recognizing these challenges, individuals seeking to overcome the hurdles of thesis writing on VAP
may find solace in the services provided by ⇒ HelpWriting.net ⇔. This specialized platform offers
expert assistance in crafting well-researched and professionally written theses on Ventilator-
Associated Pneumonia. By entrusting their academic endeavors to experienced professionals,
individuals can ensure the quality and depth of their work, allowing them to focus on other aspects
of their academic journey.

In conclusion, writing a thesis on Ventilator-Associated Pneumonia is undoubtedly a formidable task,

requiring a blend of medical expertise, research skills, and time commitment. For those navigating
the complexities of this subject, seeking assistance from ⇒ HelpWriting.net ⇔ can prove to be a
valuable investment, providing the support needed to produce a scholarly and insightful thesis.
The bacteriologic strategy uses quantitative cultures of lower. Categorical variables were compared
with the Chi-square or Fisher’s exact tests. Comparison of ventilator-associated pneumonia (VAP)
rates publically reported in the United States with those in European and other comparable nations.
NationalLatest Updates to the Canadian VAP Guidelines - What's New. We discuss recent changes
in VAP surveillance nomenclature incorporating ventilator-associated conditions and ventilator-
associated events, terms recently proposed by the Centers for Disease Control. Wan Ahmad Asyraf
bin Wan Md Adnan Moderator: Dr Nik Azman bin Nik Adib. This article is an open access article
distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (
). Nosocomial Infections Not present or incubating upon admission to the hospital (48hr rule). Initial
empiric therapy should be adapted to local patterns. Diagnosis of ventilator-associated pneumonia:
controversies and working toward a gold standard. Moreover, all patients had at least one lower
respiratory tract sample processed for culture at onset of pneumonia, and the frequency and type of
previous antibiotic treatment is reported, without differences related to severity of oxygenation in
both variables. Combined dysfunctions of immune cells predict nosocomial infection in critically ill
patients. Decreases the VAP rate but increases the risk of GI bleeding by 4%. Journal of
Pharmaceutical and BioTech Industry (JPBI). Journal intensive care medicine. 2009; 24 (1):54-62.
Bacteria can colonize in the oropharyngeal area, and these pathogens can be aspirated into the lungs,
causing infection. By: Erika Rodriguez RN, BSc Shanay Jackson RN Stephen Jaime RN, BSc
Mykell Johnston RN, BSc Ashley Valencia RN, BSc Mayra Valenzuela RN, BSc. Journal intensive
care medicine. 2009; 24 (1):54-62 Selected References. The use of oxygenation has been proposed in
many diseases as a criterion for diagnosis. Economic burden of ventilator-associated pneumonia
based on total resource utilization. HKSCCM Annual Scientific Meeting 2013 Dr Arthur Chun-Wing
Lau Associate Consultant, ICU, Pamela Youde Nethersole Eastern Hospital 8 th December, 2013.
High incidence of Ventilator Associated Pneumonia September 2007-August 2008 11 cases.
Challenge:. What We Did. Feature papers are submitted upon individual invitation or
recommendation by the scientific editors and must receive. When fever, leukocytosis, purulent
sputum, and a positive. It is one of the most important nosocomial infections encountered in the
intensive care unit (ICU). TREATMENT- Antibiotics,zantac, iron folic acid, clexan and supportive
treatment NGT. Importantly, the aetiology of hypoxemia is not part of this definition. Chesley
Richards, MD, MPH Deputy Director Division of Healthcare Quality Promotion National Center for
Infectious Disease Centers for Disease Control and Prevention. A ventilator is a device used to
provide assisted respiration and positive-pressure breathing. Therefore, until more specific diagnostic
criteria are available, initiation of antimicrobial treatment should still be based on the clinical signs of
infection together with radiographic criteria.
Quantitative versus qualitative cultures of respiratory secretions for clinical outcomes in patients with
ventilator-associated pneumonia. HKSCCM Annual Scientific Meeting 2013 Dr Arthur Chun-Wing
Lau Associate Consultant, ICU, Pamela Youde Nethersole Eastern Hospital 8 th December, 2013.
Decreases the VAP rate but increases the risk of GI bleeding by 4%. Incidence of and risk factors for
ventilator-associated pneumonia in critically ill patients. Find support for a specific problem in the
support section of our website. Chlorhexidine, toothbrushing, and preventing ventilator associated
pneumonia in critically ill adults. Expand 33 PDF Save Impact of previous antimicrobial therapy on
the etiology and outcome of ventilator-associated pneumonia. Monotherapy is also the standard
when gram-positive. NOTE: We only request your email address so that the person you are
recommending the page to knows that you wanted them to see it, and that it is not junk mail. Finally,
there has been significant evolution for the surveillance of VAP. Cochrane Database Syst Rev.
2011;10, CD007577. PubMed. By: Erika Rodriguez RN, BSc Shanay Jackson RN Stephen Jaime
RN, BSc Mykell Johnston RN, BSc Ashley Valencia RN, BSc Mayra Valenzuela RN, BSc. There
was no statistically significant difference in the rates of VAP in these two treatment groups,
suggesting that pre-treatment with chlorhexidine is ineffective at preventing VAP and that the
clinician should focus on more important tasks during intubation. An official multi-society statement:
ventilator-associated events: the new definition. Journal of Otorhinolaryngology, Hearing and
Balance Medicine (JOHBM). This material may not be published, broadcast, rewritten or
redistributed in any form without prior authorization. Jordi Rello Vicenc Ausino M. Ricart J. Castella
Guillem Prats Medicine Chest 1993 OBJECTIVE. Diagnostic techniques that identify etiologic
pathogens on the basis of. Bela Patel, MD Tammy Campos, RN, MSN Ruth Siska, RN. It also
reviews key players involved in the therapeutic development for Ventilator Associated Pneumonia
(VAP) and special features on late-stage and discontinued projects. Soluble triggering receptor
expressed on myeloid cells and the diagnosis of pneumonia. Given that this is a simple intervention,
it is worth implementing unless there are contraindications in the specific patient. In many
institutions where there is significant antibiotic resistance, to ensure that the empiric coverage is
appropriate, double antipseudomonal coverage is required to ensure that all the responsible
pathogens are susceptible to a least one of the antibiotics. Ferrer, Miquel, Telma Sequeira, Catia
Cilloniz, Cristina Dominedo, Gianluigi Li Bassi, Ignacio Martin-Loeches, and Antoni Torres.
Introduction. Most patients who receive mechanical ventilatory support for a protracted period
develop microbial colonisation of the airway A subset of these patients develops invasive infection
requiring antibiotics. Subglottic secretion drainage for the prevention of ventilator-associated
pneumonia: a systematic review and meta-analysis. Digestants and Carminatives.pdf Digestants and
Carminatives.pdf Target pain receptors with essential oils Target pain receptors with essential oils
Cell cytoskeleton and molecular motors.pdf Cell cytoskeleton and molecular motors.pdf Bursitis is
inflammation or irritation of a bursa sac. A diagnostic thoracentesis to rule out a complicating
empyema. In their own words: Patients and families define high-quality palliative care in the
intensive care unit Critical Care Medicine. 38(3):808-818, March 2010. 2. To the extent possible, we
rely predominantly on data from randomized control trials (RCTs) and meta-analyses.
To the extent possible, we rely predominantly on data from randomized control trials (RCTs) and
meta-analyses. By: Erika Rodriguez RN, BSc Shanay Jackson RN Stephen Jaime RN, BSc Mykell
Johnston RN, BSc Ashley Valencia RN, BSc Mayra Valenzuela RN, BSc. Previous Article in Special
Issue Impact of Cefotaxime Non-susceptibility on the Clinical Outcomes of Bacteremic
Pneumococcal Pneumonia. Journal of Pharmaceutical and BioTech Industry (JPBI). Microbial profile
of early and late onset ventilator associated pneumonia in the intensive care unit of a tertiary care
hospital in Bangalore, India. They are advantageous in that they are objective, are easier to collect
and can be tracked and quantified using electronic medical records. Bursitis is inflammation or
irritation of a bursa sac. Journal of Low Power Electronics and Applications (JLPEA). CDC
Guidelines for Preventing Healthcare Associated Pneumonia, 2003. Soluble triggering receptor
expressed on myeloid cells-1 (sTREM-1) as a diagnostic marker of ventilator-associated pneumonia.
Increase rate of VAP by increasing gastric Ph leading to colonization of. A ventilator is a device used
to provide assisted respiration and positive-pressure breathing. The Kaplan-Meier curves were used
to compare survival in the two groups. Potentially resistant microorganisms in intubated patients with
hospital-acquired pneumonia: the interaction of ecology, shock and risk factors. High incidence of
Ventilator Associated Pneumonia September 2007-August 2008 11 cases. Challenge:. What We Did.
Using this threshold may underestimate the incidence of VAP. Comparison of the bacterial etiology
of early-onset and late-onset ventilator-associated pneumonia in subjects enrolled in 2 large clinical
studies. Feature papers are submitted upon individual invitation or recommendation by the scientific
editors and must receive. Introduction. Most patients who receive mechanical ventilatory support for
a protracted period develop microbial colonisation of the airway A subset of these patients develops
invasive infection requiring antibiotics. HKSCCM Annual Scientific Meeting 2013 Dr Arthur Chun-
Wing Lau Associate Consultant, ICU, Pamela Youde Nethersole Eastern Hospital 8 th December,
2013. In institutions or ICUs with high rates of MRSA or where there are risk factors for MRSA,
gram-positive coverage should include either vancomycin or linezolid. VAT is characterized by signs
of respiratory infection. A number of evidence based strategies have been described for the
prevention of ventilator associated pneumonia, and its incidence can be reduced by combining
several in a care bundle. 4 The purpose of this review is to update readers on the diagnosis,
management, and prevention of this serious infection. Tropical Medicine and Infectious Disease
(TropicalMed). Economic burden of ventilator-associated pneumonia based on total resource
utilization. Noninvasive positive-pressure ventilation as a weaning strategy for intubated adults with
respiratory failure. A diagnostic thoracentesis to rule out a complicating empyema. Chesley Richards,
MD, MPH Deputy Director Division of Healthcare Quality Promotion National Center for Infectious
Disease Centers for Disease Control and Prevention. Ventilator-associated pneumonia (VAP) occurs
in 10-20% of intubated patients. Quantitative continuous variables were compared using the
unpaired Student’s t -test or the Mann-Whitney test for normally and not normally distributed
variables, respectively.
Aerosolized antibiotics have not been proven to have value in. Microbial profile of early and late
onset ventilator associated pneumonia in the intensive care unit of a tertiary care hospital in
Bangalore, India. Short-course versus prolonged-course antibiotic therapy for hospital-acquired
pneumonia in critically ill adults. Assessment of intraoperative microaspiration: does a modified cuff
shape improve sealing. Only 1 mL of BAL aspirate is required for culture and. Attributable mortality
of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised
prevention studies. Chlorhexidine, toothbrushing, and preventing ventilator associated pneumonia in
critically ill adults. Previous Article in Special Issue Impact of Cefotaxime Non-susceptibility on the
Clinical Outcomes of Bacteremic Pneumococcal Pneumonia. Bursitis is inflammation or irritation of
a bursa sac. The administration of empiric antimicrobial therapy should therefore be initiated as early
as possible when VAP is suspected. Craven Medicine 2016 TLDR V VAT was a risk factor for
increased ventilator days, longer length of ICU and hospital stay, and the time window from VAT to
VAP allowed physicians to identify the pathogens and sensitivity profile needed to treat VAT with
appropriate antibiotics. Journal of Cardiovascular Development and Disease (JCDD). CDC
Guidelines for Preventing Healthcare Associated Pneumonia, 2003. This report provides
comprehensive information on the therapeutic development for Ventilator Associated Pneumonia
(VAP), complete with comparative analysis at various stages, therapeutics assessment by drug target,
mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest
updates, and featured news and press releases. Antimicrob Resist Infect Control. 2012;1(1):28.
Article. High incidence of Ventilator Associated Pneumonia September 2007-August 2008 11 cases.
Challenge:. What We Did. Data were prospectively collected from 2007 to 2017. Surveillance for
VAE has not been shown to improve patient outcomes and further study is required. HKSCCM
Annual Scientific Meeting 2013 Dr Arthur Chun-Wing Lau Associate Consultant, ICU, Pamela
Youde Nethersole Eastern Hospital 8 th December, 2013. For more information on the journal
statistics, click here. Cilloniz is the recipient of a Postdoctoral Grant (Strategic Plan for Research and
Innovation in Health-PERIS 2016-2020). Visit our dedicated information section to learn more about
MDPI. There was, however, no statistically significant difference between the two cohorts in
mortality, length of ICU stay and duration of mechanical ventilation. Expand 97 Save New
diagnostic methods for pneumonia in the ICU I. To present a clinical case illustrating the problem of
ventilator-associated pneumonia (VAP)To discuss the diagnosis and management of VAP, along with
a review of the evidenceTo highlight controversies in dealing with VAP. What's hot ( 20 ) VAP
BUNDLE, VENTILATOR ASSOCIATED PNEUMONIA BUNDLE VAP BUNDLE,
VENTILATOR ASSOCIATED PNEUMONIA BUNDLE ventilator Associated Pneumonia -By
Dr.Tinku Joseph ventilator Associated Pneumonia -By Dr.Tinku Joseph Prevention of ventilator
associated pneumonia Prevention of ventilator associated pneumonia Ventilator associated
pneumonia in the icu Ventilator associated pneumonia in the icu NationalLatest Updates to the
Canadian VAP Guidelines - What's New. GERIATRIC PHARMACOLOGY Geriatric pharmacology
is a specialized field focusing. Unfortunately, a reference standard for VAP remains elusive, and
further advances in rapid, definitive diagnosis may lie in the use of biomarkers from the serum or
BALF although this will not occur in the near future. We hypothesized that patients with more
impaired oxygenation would have more frequently etiologic diagnosis and therefore they would be
considered as definitive VAP episodes. In contrast, patients not at risk for infection with MDR
organisms had higher rates of MSSA, S.
Comparison of methicillin-resistant and methicillin-sensitive episodes. There are many preventative
modalities which have been demonstrated to be effective. Treatment Bacteriology Strategy for
Antibiosis Duration of Therapy 4. Ideally, the prevention of VAEs, as for traditional VAP, could
ultimately improve patient outcomes and decrease health care cost; however, at this point, it is
unknown if this will happen and studies are needed to determine this. All patients with suspected
VAP should have blood cultures. Clinical outcomes of linezolid vs vancomycin in methicillin-
resistant Staphylococcus aureus ventilator-associated pneumonia: retrospective analysis. Higher
clinical success in patients with ventilator-associated pneumonia due to methicillin-resistant
Staphylococcus aureus treated with linezolid compared with vancomycin: results from the IMPACT-
HAP study. Crit Care. 2014;18(3):R118. Article. Ventilator-associated pneumonia (VAP) occurs in
10-20% of intubated patients. After at least 3 days of mechanical ventilation and within 2 days of. A
biomarker panel (Bioscore) incorporating monocytic surface and soluble TREM-1 has high
discriminative value for ventilator-associated pneumonia: a prospective observational study. PLoS
ONE. 2014;9(10), e109686. Article. International Journal of Environmental Research and Public
Health (IJERPH). Please note that many of the page functionalities won't work as expected without
javascript enabled. Impact of inappropriate antibiotic therapy on mortality in patients with ventilator-
associated pneumonia and blood stream infection: a meta-analysis. It is one of the most important
nosocomial infections encountered in the intensive care unit (ICU). - PowerPoint PPT Presentation.
These include the utilization of NIPPV, oral hygiene measures, modification of ETTs (subglottic
secretion drainage or silver-coated) and positioning. In the absence of demonstrated superiority of
one technique over another, the relative invasiveness of bronchoscopy and its requirement for
specialized expertise and equipment, endotracheal aspirates are the preferred method of respiratory
tract sampling for microbiology. Expand 97 Save New diagnostic methods for pneumonia in the ICU
I. National Healthcare Safety Network report, data summary for 2011, device-associated module.
Ventilator-associated pneumonia (VAP) occurs in 10-20% of intubated patients. Definition of
abbreviations: IL: interleukin; TNF: tumor necrosis factor; MR-proADM: mid-regional pro-
adrenomedullin. TREATMENT-Aspirin, Plavix, Clexan, Captopril, Zocar, Amiodarone. The
administration of empiric antimicrobial therapy should therefore be initiated as early as possible
when VAP is suspected. Attributable mortality of ventilator-associated pneumonia: a meta-analysis
of individual patient data from randomised prevention studies. In order to be human-readable, please
install an RSS reader. The decision on the antimicrobial management of VAP is a multifaceted that
begins with consideration of the duration of ventilation; risk factors for infection with MDR
organisms; and the potential causative microorganisms based on institutional factors, prior cultures
and any screening that has taken place. Comparison of ventilator-associated pneumonia (VAP) rates
publically reported in the United States with those in European and other comparable nations.
Clinical and economic consequences of ventilator-associated pneumonia: a systematic review. Journal
intensive care medicine. 2009; 24 (1):54-62 Selected References. Clinical and economic
consequences of ventilator-associated pneumonia: a systematic review. Bacteria can colonize in the
oropharyngeal area, and these pathogens can be aspirated into the lungs, causing infection.