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Nejmc 2001468
Nejmc 2001468
C or r e sp ondence
Flight to
China
Visit to Germany Symptoms
Index Patient
Attended business
meetings Positive PCR
Positive PCR
Attended business Symptoms
Patient 1
meetings
Positive PCR
Attended business Symptoms
Patient 2
meetings
Positive PCR
Symptoms
Patient 3 C C
Positive PCR
Symptoms
Patient 4 C C C C
Jan. Jan. Jan. Jan. Jan. Jan. Jan. Jan. Jan. Jan. Jan.
19 20 21 22 23 24 25 26 27 28 29
Date
Figure 1. Timeline of Exposure to Index Patient with Asymptomatic 2019-CoV Infection in Germany.
the influenza season in the northern hemi- Michael Hoelscher, M.D., Ph.D.
sphere — research is needed to determine University Hospital LMU Munich
whether such patients can be treated with ap- Munich, Germany
propriate guidance and oversight outside the Disclosure forms provided by the authors are available with
the full text of this letter at NEJM.org.
hospital.
Camilla Rothe, M.D. This letter was published on January 30, 2020, and updated on
February 6, 2020, at NEJM.org.
Mirjam Schunk, M.D.
Peter Sothmann, M.D. 1. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from
Gisela Bretzel, M.D. patients with pneumonia in China, 2019. N Engl J Med 2020;382:
Guenter Froeschl, M.D. 727-33.
2. Corman V, Bleicker T, Brünink S, et al. Diagnostic detec-
Claudia Wallrauch, M.D. tion of Wuhan coronavirus 2019 by real-time RT-PCR. Geneva:
Thorbjörn Zimmer, M.D. World Health Organization, January 13, 2020 (https://www
Verena Thiel, M.D. .who.int/docs/default-source/coronaviruse/wuhan-virus-assay
-v1991527e5122341d99287a1b17c111902.pdf).
Christian Janke, M.D. 3. Callaway E, Cyranoski D. China coronavirus: six questions
University Hospital LMU Munich scientists are asking. Nature 2020;577:605-7.
Munich, Germany
rothe@lrz.uni-muenchen.de DOI: 10.1056/NEJMc2001468