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  • CBL 1st Year MBBS 27-03-24

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    Junaid Shah
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    A 35-year-old pregnant woman was brought to the hospital unconscious after 12 hours. She had a history of hypertension for 5 years but had only been on safe anti-hypertensive drugs for the past 3 months of her pregnancy. A CT scan revealed a blood clot in a major cerebral artery. The consultant diagnosed a major thromboembolism and recommended immediate intravenous therapy with an anti-coagulant glycosaminoglycan to dissolve the clot from the artery.

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    CBL 1st year MBBS 27-03-24

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    A 35-year-old pregnant woman was brought to the hospital unconscious after 12 hours. She had a history of hypertension for 5 years but had only been on safe anti-hypertensive drugs for the past 3 months of her pregnancy. A CT scan revealed a blood clot in a major cerebral artery. The consultant diagnosed a major thromboembolism and recommended immediate intravenous therapy with an anti-coagulant glycosaminoglycan to dissolve the clot from the artery.

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    3 views1 page

    CBL 1st Year MBBS 27-03-24

    Uploaded by

    Junaid Shah
    A 35-year-old pregnant woman was brought to the hospital unconscious after 12 hours. She had a history of hypertension for 5 years but had only been on safe anti-hypertensive drugs for the past 3 months of her pregnancy. A CT scan revealed a blood clot in a major cerebral artery. The consultant diagnosed a major thromboembolism and recommended immediate intravenous therapy with an anti-coagulant glycosaminoglycan to dissolve the clot from the artery.

    Copyright:

    © All Rights Reserved
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    of 1

    Liaquat University of

    DEPARTMENT OF BIOCHEMISTRY
    Medical & Health “SAY NO TO CORRUPTION”
    Sciences Jamshoro

    CBL for 1st Year MBBS


    Theme: Cerebral Embolism
    Sub theme: Role of Heteropolysaccharides in management of
    thromboembolism
    Clinical Scenario:

    A 35-year-old pregnant lady referred to hospital due to unconsciousness since 12


    hours. On medical history from her family, they told she already suffering from
    hypertension since last five years but due to pregnancy anti-hypertensive drugs
    stopped and only safe group is giving from last three months. On physical
    examination her systolic blood pressure was 160 mmHg & diastolic B.P was
    120mmHg, CT scan brain reveals there was blood clot present at major cerebral
    artery. Consultant decided there is major thromboembolism in cerebral artery. For
    her treatment they recommended immediate intravenous therapy of anti-coagulant
    which is basically major glycosaminoglycan to resolve the embolism from major
    artery.

    Point to be discussed:

    Q1: Define Glycosaminoglycan’s?


    Q2: What is the most common glycosaminoglycan?
    Q3: Which glycosaminoglycan act as ant coagulant?
    Q4: What is the function of glycosaminoglycan?
    Q5: What is the difference between GAGs and proteoglycans?
    Q6: What are glycosaminoglycan in skin?

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