Professional Documents
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159᎐169
Special article
S.R. KovacU
Department of Gynecology and Obstetrics, Emory Uni¨ ersity School of Medicine, Atlanta, GA, USA
Received 15 January 2000; received in revised form 7 June 2000; accepted 19 June 2000
Abstract
Objecti¨ e: This study was undertaken to determine if the use of formal guidelines in selecting the route of
hysterectomy would improve medical and economic outcomes. Method: Data from 4595 hysterectomies performed at
a single center in women whose primary diagnosis were unrelated to invasive cancer or pregnancy were analyzed in
terms of mean, uterine weight, costs, length of stay, and complications. Results: When formal guidelines were used to
determine the route of hysterectomy, vaginal hysterectomy was performed in 90% of the patients treated and in
100% of the patients in whom the pathology was confined to the uterus. In comparison, when formal guidelines were
not incorporated in the decision-making process, vaginal hysterectomy was performed in 42% of the patients treated
and in 64% of the patients in whom the pathology was confined to the uterus. Conclusions: Using these or similar
guidelines to assist in clinical decision making would have resulted in a potential savings of US$1 184 000 for every
1000 hysterectomies performed at the institution where this study was undertaken and would have freed up 1020
patient-bed days and reduced complications by approximately 20%. 䊚 2000 International Federation of Gynecology
and Obstetrics All rights reserved.
Keywords: Abdominal hysterectomy, AH; Decision making; Economics; Hysterectomy; Laparoscopically assisted vaginal hysterec-
tomy; LAVH; Vaginal hysterectomy, VH
U Department of Gynecology and Obstetrics, Emory University School of Medicine, 69 Butler Street S.E., Atlanta, GA 30303,
USA. Tel.: q1-404-616-3540; fax: q1-404-521-3589.
E-mail address: pelvicsurg@aol.com ŽS.R. Kovac..
0020-7292r00r$20.00 䊚 2000 International Federation of Gynecology and Obstetrics All rights reserved.
PII: S 0 0 2 0 - 7 2 9 2 Ž 0 0 . 0 0 3 1 6 - 7
160 S.R. Ko¨ ac r International Journal of Gynecology & Obstetrics 71 (2000) 159᎐169
procedure involving laparoscopy, including total cians in the study and coded by medical record
laparoscopic hysterectomy. personnel according to ICD-9 codes. Complica-
Complications were identified on the face sheet tions were then grouped into the following seven
of the medical record by each of the 126 physi- categories using ICD-9 codes:
162 S.R. Ko¨ ac r International Journal of Gynecology & Obstetrics 71 (2000) 159᎐169
163
164 S.R. Ko¨ ac r International Journal of Gynecology & Obstetrics 71 (2000) 159᎐169
Fig. 2. Ž Continued..
S.R. Ko¨ ac r International Journal of Gynecology & Obstetrics 71 (2000) 159᎐169 165
Fig. 2a,b represent detailed diagnostic profiles Among the low-uterine-weight Type II patients,
of the study population. Overall diagnostic pro- the mean charge was lower for the DDH patients
files between the DDH patients and non-DDH compared with the others, resulting in a statisti-
patients were similar. Prolapse, bleeding, fibroids, cally significant Ž P- 0.001. per-case savings of
and adenomyosis were the most prevalent diag- US$1455. Among the high-uterine-weight cases,
noses. the difference in charges for Type I patients was
To assess the medical and economic benefits of also statistically significant Ž Ps 0.001. ŽTable 1..
applying guidelines to determine the surgical ap- The application of formal practice guidelines
proach, the outcomes of the 675 hysterectomies resulted in reduced length of stay. For Type I
in the DDH group were compared with the out- cases in both weight groups, DDH patients re-
comes of the remaining 3920 hysterectomies in quired 0.92᎐1.43 fewer days Ž P- 0.003, Bonferr-
the non-DDH group. Table 1 shows mean uterine oni bound..
weights, mean charges, and mean length of stay Table 2 compares the mean charges and mean
ŽLOS.. Compared with the non-DDH group, the LOS stay for the three types of hysterectomy.
DDH group had a significantly higher percentage Regardless of uterine weight, none of the sur-
of Type I patients in both weight groups. In the geons in either group chose VH as the primary
low-uterine-weight group, the mean uterine surgical decision before laparotomy or laparo-
weight of the DDH group was 13.3 g less than the scopy when they suspected the patient’s condition
weight of the non-DDH patients. Although this extended beyond the confines of the uterus. In
was a statistically significant difference Ž Ps 0.003, the DDH group, all 609 Type I patients under-
ANOVA, Type III F-test., it was not surgically went VH without laparoscopy, regardless of uter-
significant. In the high-uterine-weight group, the ine weight. In comparison, among Type I patients
mean uterine weight of the DDH patients was in the non-DDH group, 1647 Ž64%. women un-
slightly larger than non-DDH cases, although the derwent vaginal hysterectomies, 833 Ž32%. under-
difference was not statistically significant. went abdominal hysterectomies and 88 Ž3%. un-
The charge comparison reveals that the mean derwent LAVH. Among Type II, low-uterine-
charges of the DDH group were significantly less weight patients in the DDH group, 61 Ž96%.
than the mean charges of non-DDH cases, re- underwent laparoscopy to determine the severity
gardless of patient type or uterine weight. Among of their condition before uterine removal, result-
low-uterine-weight Type I patients, the mean ing in reduced charges and LOS when compared
charge was lower for DDH patients compared with the non-DDH group. In addition, in 4% of
with the others, resulting in a statistically signifi- the Type II DDH patients in the low-uterine-
cant Ž P- 0.001. per-case savings of US$1219. weight group, the laparoscope was not indicated
Table 1
Number of cases, mean uterus weight, mean charges, and mean LOS
Table 2
Number of cases, mean charges, and mean LOS for each procedurea
DDH group
Uterus Ib 0 ᎐ ᎐ 0 ᎐ ᎐ 559 4343 2.53
- 280 g IIc 4 6098 3.75 61 4917 2.77 0 ᎐ ᎐
Uterus Ib 0 ᎐ ᎐ 0 ᎐ ᎐ 50 4719 2.26
G 280 g IIc 1 5372 4.00 0 ᎐ ᎐ 0 ᎐ ᎐
Non-DDH group
Uterus Ib 609 6230 4.10 78 7500 2.63 1583 5209 3.23
- 280 g IIc 964 6390 4.13 228 6679 2.92 0 ᎐ ᎐
Uterus Ib 224 6052 3.94 10 8774 2.70 64 5701 2.98
G 280 g IIc 157 6422 3.92 3 8394 3.00 0 ᎐ ᎐
a
Abbre¨ iations: AH, abdominal hysterectomy; LAVH, laparoscopically assisted vaginal hysterectomy; VH, vaginal hysterectomy.
b
Type I patients displayed pathology confined to the uterus.
c
Type II patients displayed pathology extending beyond the confines of the uterus and, in most cases, Type I conditions.
because the patients exhibited vaginal inaccessi- As shown in Table 3, among the 61 LAVH
bility, which dictated an abdominal hysterectomy. Type II cases in the low-uterine-weight DDH
In comparison, among Type II, low-uterine-weight group, 57 Ž93%. procedures were completed via
patients in the non-DDH group, 228 Ž19%. women the vaginal route following diagnostic laparo-
underwent laparoscopy before uterine removal. scopy. In comparison, among Type II patients in
Among Type I, low-uterine weight patients in the the low-uterine-weight, non-DDH group, 81 Ž36%.
non-DDH group, 78 Ž3%. diagnostic laparo- of 228 LAVH procedures were completed through
scopies were performed at a mean charge of the abdominal route and 147 Ž64%. were com-
US$7500. pleted vaginally.
Table 3
Number of cases, mean charges, and mean LOS when laparoscopy was used a
Table 4
Complications Ž% of cases. a
Because of small sample sizes, it was not possi- 0.003., urinary complications Ž P- 0.003. and the
ble to compare the complication rates reported overall complication rates Ž P- 0.002. ŽTable 4..
for DDH and non-DDH patients. In order to Table 5 converts the findings into potential
compare the complication rate for AH and VH, savings per 1000 hysterectomies among patients
the rates for the DDH and non-DDH groups with uterine weights less than 280 g. The savings
were combined. Significant differences in favor of were most dramatic. Incorporating the guidelines
VH were detected for post-operative fever or and performing vaginal hysterectomy for all
infection Ž P- 0.005., intestinal obstruction Ž P- Type I patients with vaginal accessibility would
Table 5
Impact of applying the decision rule a
Diagnostic type Outcomes associated with Savings per case Savings per
and outcome Current Recommended Mean Ž%. 1000 cases
surgery surgery
Type Ib AH VH
Charges ŽUS$. 6182 4998 1184 19.2% 1 184 000
LOS Ždays. 4.05 3.03 1.02 25.2% 1020 days
Complications 9.1% 7.4% 1.7% 18.9% 17 cases wro complications
have resulted in savings of US$1 184 000 for every to extend outside of the uterus. In the DDH
1000 procedures performed at the study hospital. group, the laparoscope was employed in 96% of
Applying the guidelines would free 1020 patient- such cases and, after documenting the absence of
bed days and result in approximately a 20% re- pathologic contraindications, 93% of those diag-
duction in complications. nostic laparoscopy cases were completed vagi-
nally. In comparison, in the non-DDH group,
physicians performed diagnostic laparoscopy in
5. Discussion only 3% of Type II patients and completed 36%
of these diagnostic laparoscopy cases abdomi-
Two outcome-based studies have shown that by nally. The limited use of the laparoscope by
using a formal decision process, such as the one physicians in the non-DDH group may reflect
presented here, physicians can perform VH in they were confident enough in their diagnostic
approximately 77᎐89% of their patients w3,10x. skills that they did not require laparoscopic evi-
The results of the current study support these dence to confirm the severity of the disease or
findings and also show that economic outcomes they were convinced that AH is required when-
ᎏ hospital charges and length of stay ᎏ and ever the pathologic condition is suspected to ex-
medical outcomes, specifically complication rates, tend beyond the uterus. However, since both the
are significantly improved when the surgeon uses
DDH and non-DDH groups were similar, one can
formal guidelines to select the appropriate hys-
assume that had the severity of the disease been
terectomy route.
confirmed laparoscopically, more women would
The economic benefits of using a formal deci-
have undergone VH.
sion process were especially apparent among
Traditionally, the history, physical examination,
women whose conditions were confined to the
and imaging techniques, such as ultrasound and
uterus. The guidelines recommend VH when the
X-ray studies, have been used to determine
disease is confined to the uterus, as in the case of
whether pathology extended beyond the uterus.
prolapse, small symptomatic leiomyomata, ade-
nomyosis, recurrent or severe dysfunctional uter- However, several investigators have proven that
ine bleeding, or carcinoma in situ of the cervix. these techniques are not sufficiently accurate to
Thus, in the DDH group, VH was performed in adequately document the severity of conditions
all 609 women with disease confined to the uterus such as endometriosis, adnexal pathology, chronic
ŽType I patients. at a mean charge of US$4343 or pelvic pain, and pelvic inflammatory disease
US$4719, depending on uterine weight. Contrast w3,11,12x. As this analysis shows, judicious use of
this with the non-DDH group, where both AH the laparoscope to precisely document the sever-
and LAVH were performed at mean charges of ity of the disease process when indicated yields
US$6230 and US$7500, respectively, in some significantly improved medical and economic out-
low-uterine-weight Type I patients. Had physi- comes.
cians used a formal decision process to direct The data on complications reported in this
these women to the clinically appropriate VH study for AH and VH were statistically different
route a mean savings per case of US$1184 would and support the results of previous studies
have been realized, and the complications and showing that the vaginal route is associated with
higher hospital charges associated AH and LAVH fewer complications. Overall complication rates
could have been avoided. for the surgeons in this study, however, were
For patients with disease suspected to extend similar regardless of whether the surgeon used
beyond the confines of the uterus ŽType II., the formal guidelines presented here or another, less
benefits of the guidelines were reflected in the formal process to determine the route of hys-
frequency of diagnostic laparoscopy and the con- terectomy. This was to be expected because gyne-
version to VH. The guidelines recommend la- cologic surgeons choose procedures in which they
paroscopic examination when pathology appears are experienced and have surgical competence.
S.R. Ko¨ ac r International Journal of Gynecology & Obstetrics 71 (2000) 159᎐169 169
At the teaching hospital where this study was is cost-effective and meets the standard of quality
conducted, the ratio of AH to VH was approxi- care.
mately 1.2:1, much lower than the national ratio
of 2.06:1, which demonstrated that the surgeons
in this study were highly skilled in VH techniques. Acknowledgments
However, with the application of the formal
guidelines presented here, the VH rate increased
Statistical analysis was supported in part by an
even more.
unrestricted educational grant from Ethicon
This study is not without its weaknesses. The
Endo-Surgery, Cincinnati, Ohio.
effect of confounding variables, such as age dif-
ferences, preexisting medical conditions, and con-
comitant surgeries, including oophorectomy, vagi- References
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