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ETD HKL SPLIT DUO-MECHANICAL VENTILATION

This method of mechanical ventilation is a mitigation strategy to accommodate a sudden large influx of patient’s surge in need to support
mechanical ventilation in disaster incidence and only to be considered as a last resort once all available resources have been exhausted, goals of
care and options for palliation have been discussed with family , and the probability of survival is reasonable if shared ventilation is provided.

Patient Selection
•Similar ABW & lung mechanics (PEEP & FiO2 requirements)
•DO NOT use it for obstructive/ restrictive lungs
•Hemodynamically stable
•Non-respiratory infected patients.

Initial FiO2 and PEEP requirements may be similar, but the


lungs may recover at different rates.

Adjustments of the setting must be tailored to each individual


lungs.

Equipment
•Viral filters and one-way valve connectors to prevent cross
contamination
•ETCO2 monitoring placed in-line-> helps to monitor
ventilation efficacy
•Consider to add inline PEEP valve in patient with different
requirement

Why use pressure mode in multiple patient


Ventilator Setting ventilation using one ventilator?

Parameter Recommended Range Parameter Recommended Range Volume-mode Pressure-mode


Mode CMV/ PCV RR 12-30 per min
ventilation ventilation

TV 6-8ml/kg iTime 0.6-1.0s Guaranteed TV, however Guaranteed limitation of


multiple patients the Ppeak-> control over
IP 30cmH20 FiO2 21-100% provide no control over the maximal airway
the TV of any patient. pressure & the driving P.
PEEP 5-16cmH20 Driving P 5-18cmH20

Increase the ventilator Lack of control over Lack of control over TV


Low volume alarm. Set trigger threshold to Ppeak -> No control on but can be compensated
Alarm based on VTe of the Trigger lock out the ventilator the maximal airway with above lung-
least compliant lung. to prevent triggering of pressure. protective mechanism.
breaths.

Possible deleterious Possible deleterious


interactions between interactions between
Monitoring patients: patients can be avoided.

•Patients must remain sedated +/- paralyzed during shared Example: Example:
ventilation. • Patient 1 has a • Patient 1 has a
•Target pH 7.25-7.45: If one patient is markedly acidemic and kinked ETT-> kinked ETT->
other is alkalemia; treat acidemia with conventional Reduction in TV due Reduction in TV due
ventilator changes while alkalemia by adding dead space to to increase in to increase in airway
ventilator circuit (to induced hypercapnia). airway R. R.
• Patient 2 will • Patient 2 will not be
•Patients cannot be weaned from shared ventilation and must
receive larger TV-> affected.
be transferred to a single ventilator when available.
Risk of volutrauma.

Pearls & Pitfalls

1. Risk of inadequate ventilation: TV will be difficult to track & optimize, while FiO2, RR and I:E ratio cannot be individualized.
2. Risk of hypercapnia-> connections and tubing will increase dead space.
3. Risk of cross contamination.
4. The alarms systems are limited since the ventilator is reading combined VTe thus delaying recognition of events like obstruction of ETT
(hence it is important to carefully set the tidal volume alarm).
5. Requirement for monitoring of patients, which may be difficult given the shortage of staff with ventilation expertise.
6. Prolonged ICU stay and risk of ICU AW– patient’s withdrawal due to high requirements of sedation+ paralytics.

• Lewis et al. 2007 Definitive Care for the Critically Ill During a Disaster: Medical Resources for
• Branson RD1, Blakeman TC, Robinson BR, Johannigman JA. 2012 Use of a single ventilator to • Pearson SD, Hall JB, Parker WF Two for one with split- or co-ventilation at the peak of the Surge Capacity: From a Task Force for Mass Critical Care Summit Meeting, January 26–27,
support 4 patients: laboratory evaluation of a limited concept. Respir Care. 2012 Covid-19 tsunami: is there any role for communal care when the resources for personalised 2007, Chicago, IL Chest 2008;133(5):32S-50S
Mar;57(3):399-403. medicine are exhausted? Thorax Published Online First: 23 April 2020. doi: 10.1136/thoraxjnl- • Matthay MA, Aldrich M and Gotts JE 2020 Treatment for severe acute respiratory distress
• Chatburn RL, Branson RD and Hatipoglu U 2020 Multiplex Ventilation: A Simulation-based 2020-214929 syndrome from COVID-19. Lancet 2020. https://doi.org/10.1016/S2213-2600(20)30127-2
Study of Ventilating Two Patients with One Ventilator. RESPCARE 2020; • Siderits and Neyman Experimental 3D Printed 4-Port Ventilator Manifold for Potential Use in • Merritt, D. R.; Weinhaus, F. The Pressure Curve for a Rubber Balloon", American Journal of
10.4187/respcare.07882 Disaster Surges. Open Journal of Emergency Medicine, 2014;2:46-48 Physics, 1978;46(10). https://doi.org/10.1119/1.11486
• Clarke AL, Stephens AF, Liao S, Byrne TJ and Gregory SD 2020 Coping with COVID-19: ventilator • Smith R og Brown JM Simultaneous ventilation of two healthy subjects with a single ventilator. • Neyman G and Irvin CB 2006 A Single Ventilator for Multiple Simulated Patients to Meet
splitting with differential driving pressures using standard hospital equipment. Anaesthesia. Letter to the Editor. Resuscitation. 2009;80:1087. Disaster Surge. Academic Emergency Medicine 2006; 13:1246–1249
2020 Apr 09 [Online ahead of print] • Tonetti T, Zanella A, Pizzilli G, et alOne ventilator for two patients: feasibility and • International working group on differential multiventilation (www.differentialmultivent.org).
• Han et al 2020 Personalized Ventilation to Multiple Patients Using a Single Ventilator: considerations of a last resort solution in case of equipment shortageThorax Published Online • Paladino L et al. 2008 Increasing ventilator surge capacity in disasters: Ventilation of four
Description and Proof of Concept. Critical Care Explorations: May 2020 - Volume 2 - Issue 5 - p First: 23 April 2020. doi: 10.1136/thoraxjnl-2020-214895 adult-human- sized sheep on a single ventilator with a modified circuit Resuscitation Volume
e0118 • World Health Organization. Clinical management of severe acute respiratory infection (SARI) 77, Issue 1, April 2008, Pages 121-126
• Herrmann J, Fonseca da Cruz A, Hawley ML, Brandon RD and Kaczka DW Shared Ventilation in when COVID-19 disease is suspected Interim guidance 13 March 2020. • Branson 2008 Resuscitation 2008;79:171-172
the Era of COVID-19: A Theoretical Consideration of the Dangers and Potential Solutions. https://www.who.int/docs/default- source/coronaviruse/clinical-management-of-novel-
Respiratory Care May 2020, respcare.07919; DOI: https://doi.org/10.4187/respcare.07919 cov.pdf

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