Scribd Logo
Upload

Welcome to Scribd!

  • Inflammatory Breast Cancer

    Uploaded by

    ashentaxpayee
    3 views1 page
    Inflammatory breast cancer is treated similarly to locally advanced breast cancer, with initial chemotherapy including anthracycline and taxane, plus trastuzumab and pertuzumab if HER2 positive. The response is then checked, and if positive, mastectomy and clearance is followed by radiation and reconstruction before adjuvant therapy including completing chemotherapy, and hormone therapy if receptors are positive, as well as trastuzumab and pertuzumab for one year. If no initial response, additional chemotherapy and radiation is considered.

    Original Description:

    Original Title

    8. Inflammatory Breast Cancer

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Inflammatory breast cancer is treated similarly to locally advanced breast cancer, with initial chemotherapy including anthracycline and taxane, plus trastuzumab and pertuzumab if HER2 positive. The response is then checked, and if positive, mastectomy and clearance is followed by radiation and reconstruction before adjuvant therapy including completing chemotherapy, and hormone therapy if receptors are positive, as well as trastuzumab and pertuzumab for one year. If no initial response, additional chemotherapy and radiation is considered.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    3 views1 page

    Inflammatory Breast Cancer

    Uploaded by

    ashentaxpayee
    Inflammatory breast cancer is treated similarly to locally advanced breast cancer, with initial chemotherapy including anthracycline and taxane, plus trastuzumab and pertuzumab if HER2 positive. The response is then checked, and if positive, mastectomy and clearance is followed by radiation and reconstruction before adjuvant therapy including completing chemotherapy, and hormone therapy if receptors are positive, as well as trastuzumab and pertuzumab for one year. If no initial response, additional chemotherapy and radiation is considered.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    INFLAMMATORY BREAST CANCER

    • Same as Locally advanced breast cancer management


    • Same work up
    • Initial management is with chemotherapy
    ◦ Antrhacycline + Taxane preferred
    ◦ If HER2 positive → Trastuzumab + Pertuzumab both should ideally be given
    • Check response
    • If responded
    ◦ Mastectomy + Axillary clearance
    ◦ Followed by radiation to chest wall, supraclavicular area + internal mammary nodes if they are
    involved
    ◦ Delayed breast reconstruction
    ◦ Then proceed to adjuvant
    ‣ Complete planned chemotherapy regimen
    ‣ Endocrine therapy if ER/PR +ve to be given sequentially after CT is over
    ‣ Trastuzumab + Pertuzumab to be completed for a period of 1 year
    • If no response
    ◦ Consider addition chemo + RT
    ◦ If responded → above management
    ◦ If no response → individualized management

    You might also like